Project acronym LONGWOOD
Project Long-term woodland dynamics in Central Europe: from estimations to a realistic model
Researcher (PI) Péter Szabó
Host Institution (HI) BOTANICKY USTAV AV CR, V.V.I.
Call Details Starting Grant (StG), PE10, ERC-2011-StG_20101014
Summary The vegetation of Central Europe has been directly influenced by humans for at least eight millennia; the original forests have been gradually transformed into today’s agricultural landscape. However, there is more to this landscape change than the simple disappearance of woodland. Forests have been brought under various management regimes, which profoundly altered their structure and species composition. The details of this process are little known for two main reasons. The greatest obstacle is the lack of cooperation among the disciplines dealing with the subject. The second major problem is the differences in spatio-temporal scaling and resolution used by the individual disciplines. Existing studies either concern smaller territories, or cover large areas (continental to global) with the help of modelling-based generalizations rather than primary data from the past. Using an extensive range of primary sources from history, historical geography, palaeoecology, archaeology and ecology, this interdisciplinary project aims to reconstruct the long-term (Neolithic to present) patterns of woodland cover, structure, composition and management in a larger study region (Moravia, the Czech Republic, ca. 27,000 km2) with the highest spatio-temporal resolution possible. Causes for the patterns observed will be analyzed in terms of qualitative and quantitative factors, both natural and human-driven, and the patterns in the tree layer will be related to those in the herb layer, which constitutes the most important part of plant biodiversity in Europe. This project will introduce woodland management as an equal driving force into long-term woodland dynamics, thus fostering a paradigm shift in ecology towards construing humans as an internal, constitutive element of ecosystems. By integrating sources and methods from the natural sciences and the humanities, the project will provide a more reliable basis for woodland management and conservation in Central Europe.
Summary
The vegetation of Central Europe has been directly influenced by humans for at least eight millennia; the original forests have been gradually transformed into today’s agricultural landscape. However, there is more to this landscape change than the simple disappearance of woodland. Forests have been brought under various management regimes, which profoundly altered their structure and species composition. The details of this process are little known for two main reasons. The greatest obstacle is the lack of cooperation among the disciplines dealing with the subject. The second major problem is the differences in spatio-temporal scaling and resolution used by the individual disciplines. Existing studies either concern smaller territories, or cover large areas (continental to global) with the help of modelling-based generalizations rather than primary data from the past. Using an extensive range of primary sources from history, historical geography, palaeoecology, archaeology and ecology, this interdisciplinary project aims to reconstruct the long-term (Neolithic to present) patterns of woodland cover, structure, composition and management in a larger study region (Moravia, the Czech Republic, ca. 27,000 km2) with the highest spatio-temporal resolution possible. Causes for the patterns observed will be analyzed in terms of qualitative and quantitative factors, both natural and human-driven, and the patterns in the tree layer will be related to those in the herb layer, which constitutes the most important part of plant biodiversity in Europe. This project will introduce woodland management as an equal driving force into long-term woodland dynamics, thus fostering a paradigm shift in ecology towards construing humans as an internal, constitutive element of ecosystems. By integrating sources and methods from the natural sciences and the humanities, the project will provide a more reliable basis for woodland management and conservation in Central Europe.
Max ERC Funding
1 413 474 €
Duration
Start date: 2012-01-01, End date: 2016-12-31
Project acronym microCODE
Project Microfluidic Combinatorial On Demand Systems: a Platform for High-Throughput Screening in Chemistry and Biotechnology
Researcher (PI) Piotr Garstecki
Host Institution (HI) INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK
Call Details Starting Grant (StG), PE4, ERC-2011-StG_20101014
Summary This proposal addresses an important opportunity in the rapidly developing art of microfluidics. On one hand vast expertise is available on automation of single phase flows via microvalves or electrokinetics and on flow of drops on planar electrodes. These systems are perfectly suited for a range of applications but are inherently inefficient in handling massively large numbers of processes due to correspondingly large number of input/output controls that at best scales logarithmically in the number of processes. On the other hand conducting reactions in thousands micro droplets embodies many of the most acclaimed promises of microfluidics – ultra-miniaturisation, speed, rapid mixing and extensive control of physical conditions. Demonstrations of incubation of cells, in-vitro translation and directed evolution confirm that these techniques can reduce the cost and time of existing processes by orders of magnitude. Droplet microfluidics is at the moment, however, almost (except sorting) completely passive.
We recently demonstrated the use of external valves to automate formation and motion of droplets on simple disposable chips and screening up to 10000 compositions per hour. We propose to develop externally controlled programmable modules for i) multiplexed, on-demand generation of multiple emulsions, ii) aspiration of libraries of samples and multiplexing linear libraries into full cross matrices, iii) splitting drops into two, few and large numbers (e.g. 10000) drops, iv) optical monitoring of presence and content of droplets, v) counting cells inside the drops, vi) circulating drops, vii) titration, viii) holding paramagnetic beads in drops. Our design rules will allow to integrate these modules into externally controlled systems for research on i) combinatorial synthesis, ii) material science, iii) role of noise in metabolic networks, iv) evolution of bacteria, v) inexpensive multiplexed diagnostics systems, including cytometry, PCR and ELISA assays in drops.
Summary
This proposal addresses an important opportunity in the rapidly developing art of microfluidics. On one hand vast expertise is available on automation of single phase flows via microvalves or electrokinetics and on flow of drops on planar electrodes. These systems are perfectly suited for a range of applications but are inherently inefficient in handling massively large numbers of processes due to correspondingly large number of input/output controls that at best scales logarithmically in the number of processes. On the other hand conducting reactions in thousands micro droplets embodies many of the most acclaimed promises of microfluidics – ultra-miniaturisation, speed, rapid mixing and extensive control of physical conditions. Demonstrations of incubation of cells, in-vitro translation and directed evolution confirm that these techniques can reduce the cost and time of existing processes by orders of magnitude. Droplet microfluidics is at the moment, however, almost (except sorting) completely passive.
We recently demonstrated the use of external valves to automate formation and motion of droplets on simple disposable chips and screening up to 10000 compositions per hour. We propose to develop externally controlled programmable modules for i) multiplexed, on-demand generation of multiple emulsions, ii) aspiration of libraries of samples and multiplexing linear libraries into full cross matrices, iii) splitting drops into two, few and large numbers (e.g. 10000) drops, iv) optical monitoring of presence and content of droplets, v) counting cells inside the drops, vi) circulating drops, vii) titration, viii) holding paramagnetic beads in drops. Our design rules will allow to integrate these modules into externally controlled systems for research on i) combinatorial synthesis, ii) material science, iii) role of noise in metabolic networks, iv) evolution of bacteria, v) inexpensive multiplexed diagnostics systems, including cytometry, PCR and ELISA assays in drops.
Max ERC Funding
1 749 600 €
Duration
Start date: 2012-01-01, End date: 2016-12-31
Project acronym OGLEIV
Project Optical Gravitational Lensing Experiment: New Frontiers in Observational Astronomy
Researcher (PI) Andrzej Udalski
Host Institution (HI) UNIWERSYTET WARSZAWSKI
Call Details Advanced Grant (AdG), PE9, ERC-2009-AdG
Summary We apply for financial support for the new, fourth phase of the Optical Gravitational Lensing Experiment (OGLE-IV) - one of the largest scale sky surveys worldwide, operating continuously since 1992. During its operation the OGLE project contributed significantly to many fields of modern astrophysics including gravitational microlensing, extrasolar planets searches, stellar astrophysics, Galactic structure and many others. The main scientific goal of the OGLE-IV phase will be the second generation planetary microlensing survey. It should result in top rank discoveries of the Earth mass planets and should provide the full census of planets down to Earth masses orbiting their hosts at 1-5 AU orbits. This parameter space is only accessible to the microlensing technique. Complementary census of planets orbiting at the distances smaller that 1 AU is to be made by space missions using transit technique. OGLE-IV survey will also conduct research in many other top rank astrophysical topics like the search for Pluto size dwarf planets from the Kuiper Belt, search for free-floating black holes, microlensing in the Magellanic Clouds and Galactic disk. Hundreds of new discoveries in the variable star field are also guaranteed. Moreover, OGLE-IV will operate on-line services providing real time photometry of variable objects of many types. The OGLE-IV data will be placed in public domain and available to the astronomical community.
Summary
We apply for financial support for the new, fourth phase of the Optical Gravitational Lensing Experiment (OGLE-IV) - one of the largest scale sky surveys worldwide, operating continuously since 1992. During its operation the OGLE project contributed significantly to many fields of modern astrophysics including gravitational microlensing, extrasolar planets searches, stellar astrophysics, Galactic structure and many others. The main scientific goal of the OGLE-IV phase will be the second generation planetary microlensing survey. It should result in top rank discoveries of the Earth mass planets and should provide the full census of planets down to Earth masses orbiting their hosts at 1-5 AU orbits. This parameter space is only accessible to the microlensing technique. Complementary census of planets orbiting at the distances smaller that 1 AU is to be made by space missions using transit technique. OGLE-IV survey will also conduct research in many other top rank astrophysical topics like the search for Pluto size dwarf planets from the Kuiper Belt, search for free-floating black holes, microlensing in the Magellanic Clouds and Galactic disk. Hundreds of new discoveries in the variable star field are also guaranteed. Moreover, OGLE-IV will operate on-line services providing real time photometry of variable objects of many types. The OGLE-IV data will be placed in public domain and available to the astronomical community.
Max ERC Funding
2 498 000 €
Duration
Start date: 2010-01-01, End date: 2014-12-31
