Project acronym 3D-FABRIC
Project 3D Flow Analysis in Bijels Reconfigured for Interfacial Catalysis
Researcher (PI) Martin F. HAASE
Host Institution (HI) UNIVERSITEIT UTRECHT
Call Details Starting Grant (StG), PE8, ERC-2018-STG
Summary The objective of this proposal is to determine the unknown criteria for convective cross-flow in bicontinuous interfacially jammed emulsion gels (bijels). Based on this, we will answer the question: Can continuously operated interfacial catalysis be realized in bijel cross-flow reactors? Demonstrating this potential will introduce a broadly applicable chemical technology, replacing wasteful chemical processes that require organic solvents. We will achieve our objective in three steps:
(a) Control over bijel structure and properties. Bijels will be formed with a selection of functional inorganic colloidal particles. Nanoparticle surface modifications will be developed and extensively characterized. General principles for the parameters determining bijel structures and properties will be established based on confocal and electron microscopy characterization. These principles will enable unprecedented control over bijel formation and will allow for designing desired properties.
(b) Convective flow in bijels. The mechanical strength of bijels will be tailored and measured. With mechanically robust bijels, the influence of size and organization of oil/water channels on convective mass transfer in bijels will be investigated. To this end, a bijel mass transfer apparatus fabricated by 3d-printing of bijel fibers and soft photolithography will be introduced. In conjunction with the following objective, the analysis of convective flows in bijels will facilitate a thorough description of their structure/function relationships.
(c) Biphasic chemical reactions in STrIPS bijel cross-flow reactors. First, continuous extraction in bijels will be realized. Next, conditions to carry out continuously-operated, phase transfer catalysis of well-known model reactions in bijels will be determined. Both processes will be characterized in-situ and in 3-dimensions by confocal microscopy of fluorescent phase transfer reactions in transparent bijels.
Summary
The objective of this proposal is to determine the unknown criteria for convective cross-flow in bicontinuous interfacially jammed emulsion gels (bijels). Based on this, we will answer the question: Can continuously operated interfacial catalysis be realized in bijel cross-flow reactors? Demonstrating this potential will introduce a broadly applicable chemical technology, replacing wasteful chemical processes that require organic solvents. We will achieve our objective in three steps:
(a) Control over bijel structure and properties. Bijels will be formed with a selection of functional inorganic colloidal particles. Nanoparticle surface modifications will be developed and extensively characterized. General principles for the parameters determining bijel structures and properties will be established based on confocal and electron microscopy characterization. These principles will enable unprecedented control over bijel formation and will allow for designing desired properties.
(b) Convective flow in bijels. The mechanical strength of bijels will be tailored and measured. With mechanically robust bijels, the influence of size and organization of oil/water channels on convective mass transfer in bijels will be investigated. To this end, a bijel mass transfer apparatus fabricated by 3d-printing of bijel fibers and soft photolithography will be introduced. In conjunction with the following objective, the analysis of convective flows in bijels will facilitate a thorough description of their structure/function relationships.
(c) Biphasic chemical reactions in STrIPS bijel cross-flow reactors. First, continuous extraction in bijels will be realized. Next, conditions to carry out continuously-operated, phase transfer catalysis of well-known model reactions in bijels will be determined. Both processes will be characterized in-situ and in 3-dimensions by confocal microscopy of fluorescent phase transfer reactions in transparent bijels.
Max ERC Funding
1 905 000 €
Duration
Start date: 2019-06-01, End date: 2024-05-31
Project acronym 4D
Project Designing Devices by Doping on Demand
Researcher (PI) Arjan HOUTEPEN
Host Institution (HI) TECHNISCHE UNIVERSITEIT DELFT
Call Details Proof of Concept (PoC), ERC-2018-PoC
Summary Electronic doping, the control over the charge carrier density, is at the heart of the success of the semiconductor industry. Promising new semiconductor materials like conductive polymers, fullerenes and quantum dots cannot be doped by traditional doping methods. The applicant and his group have developed a general method to dope these materials on demand with an electrochemical method, combined with photopolymerization of the solvents and electrolyte ions. This methods allows to precisely control the charge density in these new semiconductor materials and also allows patterning of the doping density via methods akin to photolithography used in the semiconductor industry. This enable the design of new device geometries, such as lateral pn junctions that could allow easy on chip integration of e.g. solution processable LEDs. The goal of this proof-of-concept application is to investigate the application potential of this newly developed technology. In particular it involves the development of demonstrator devices to showcase the technique’s potential, to investigate and protect the intellectual property and to analyze the interest from key industrial stakeholders in this technology. When successful, this technology has the potential to revolutionize the semiconductor industry. It could be of great economic potential and in addition may contribute to achieving sustainability goals by reducing energy consumption of lamps and displays and by offering new and improved means to harvest solar via highly efficient solution processable solar cells.
Summary
Electronic doping, the control over the charge carrier density, is at the heart of the success of the semiconductor industry. Promising new semiconductor materials like conductive polymers, fullerenes and quantum dots cannot be doped by traditional doping methods. The applicant and his group have developed a general method to dope these materials on demand with an electrochemical method, combined with photopolymerization of the solvents and electrolyte ions. This methods allows to precisely control the charge density in these new semiconductor materials and also allows patterning of the doping density via methods akin to photolithography used in the semiconductor industry. This enable the design of new device geometries, such as lateral pn junctions that could allow easy on chip integration of e.g. solution processable LEDs. The goal of this proof-of-concept application is to investigate the application potential of this newly developed technology. In particular it involves the development of demonstrator devices to showcase the technique’s potential, to investigate and protect the intellectual property and to analyze the interest from key industrial stakeholders in this technology. When successful, this technology has the potential to revolutionize the semiconductor industry. It could be of great economic potential and in addition may contribute to achieving sustainability goals by reducing energy consumption of lamps and displays and by offering new and improved means to harvest solar via highly efficient solution processable solar cells.
Max ERC Funding
150 000 €
Duration
Start date: 2019-06-01, End date: 2020-11-30
Project acronym ActionContraThreat
Project Action selection under threat: the complex control of human defense
Researcher (PI) Dominik BACH
Host Institution (HI) UNIVERSITAT ZURICH
Call Details Consolidator Grant (CoG), SH4, ERC-2018-COG
Summary Run away, sidestep, duck-and-cover, watch: when under threat, humans immediately choreograph a large repertoire of defensive actions. Understanding action-selection under threat is important for anybody wanting to explain why anxiety disorders imply some of these behaviours in harmless situations. Current concepts of human defensive behaviour are largely derived from rodent research and focus on a small number of broad, cross-species, action tendencies. This is likely to underestimate the complexity of the underlying action-selection mechanisms. This research programme will take decisive steps to understand these psychological mechanisms and elucidate their neural implementation.
To elicit threat-related action in the laboratory, I will use virtual reality computer games with full body motion, and track actions with motion-capture technology. Based on a cognitive-computational framework, I will systematically characterise the space of actions under threat, investigate the psychological mechanisms by which actions are selected in different scenarios, and describe them with computational algorithms that allow quantitative predictions. To independently verify their neural implementation, I will use wearable magnetoencephalography (MEG) in freely moving subjects.
This proposal fills a lacuna between defence system concepts based on rodent research, emotion psychology, and clinical accounts of anxiety disorders. By combining a stringent experimental approach with the formalism of cognitive-computational psychology, it furnishes a unique opportunity to understand the mechanisms of action-selection under threat, and how these are distinct from more general-purpose action-selection systems. Beyond its immediate scope, the proposal has a potential to lead to a better understanding of anxiety disorders, and to pave the way towards improved diagnostics and therapies.
Summary
Run away, sidestep, duck-and-cover, watch: when under threat, humans immediately choreograph a large repertoire of defensive actions. Understanding action-selection under threat is important for anybody wanting to explain why anxiety disorders imply some of these behaviours in harmless situations. Current concepts of human defensive behaviour are largely derived from rodent research and focus on a small number of broad, cross-species, action tendencies. This is likely to underestimate the complexity of the underlying action-selection mechanisms. This research programme will take decisive steps to understand these psychological mechanisms and elucidate their neural implementation.
To elicit threat-related action in the laboratory, I will use virtual reality computer games with full body motion, and track actions with motion-capture technology. Based on a cognitive-computational framework, I will systematically characterise the space of actions under threat, investigate the psychological mechanisms by which actions are selected in different scenarios, and describe them with computational algorithms that allow quantitative predictions. To independently verify their neural implementation, I will use wearable magnetoencephalography (MEG) in freely moving subjects.
This proposal fills a lacuna between defence system concepts based on rodent research, emotion psychology, and clinical accounts of anxiety disorders. By combining a stringent experimental approach with the formalism of cognitive-computational psychology, it furnishes a unique opportunity to understand the mechanisms of action-selection under threat, and how these are distinct from more general-purpose action-selection systems. Beyond its immediate scope, the proposal has a potential to lead to a better understanding of anxiety disorders, and to pave the way towards improved diagnostics and therapies.
Max ERC Funding
1 998 750 €
Duration
Start date: 2019-10-01, End date: 2024-09-30
Project acronym ALEX
Project ALgorithms EXposed. Investigating Automated Personalization and Filtering for Research and Activism
Researcher (PI) Stefania MILAN
Host Institution (HI) UNIVERSITEIT VAN AMSTERDAM
Call Details Proof of Concept (PoC), ERC-2018-PoC
Summary Personalization algorithms—filtering content on the basis of someone's profile—increasingly mediate the web experience of users. By forging a specific reality for each individual, they silently shape customized 'information diets': in other words, they determine which news, opinions and rumors users are exposed to. Restricting users’ possibilities, they ultimately infringe on their agency. As exposed by the recent Cambridge Analytica scandal, they are supported by questionable data sharing practices at the core of the business models of the social media industry. Yet, personalization algorithms are proprietary and thus remain inaccessible to end users. The few experiments auditing these algorithms rely on data provided by platform companies themselves. They are highly technical, hardly scalable, and fail to put social media users in the driver seat. The ALgorithms EXposed (ALEX) project aims at unmasking the functioning of personalization algorithms on social media platforms, taking Facebook as a test case. It is 'data activism' in practice, as it uses publicly available data for awareness raising and citizen empowerment. ALEX will pursue five goals: 1) software development and stabilization, building on the alpha version of facebook.tracking.exposed (fbtrex), a working prototype of a browser extension analyzing the outcomes of Facebook's News Feed algorithms; 2) the release of two spin-off products building on fbtrex, namely AudIT, enabling researchers to do expert analysis on algorithmic biases, and RealityCheck, allowing users to monitor their own social media consumption patterns; 3) testing the technical feasibility of adapting the ALEX approach to analyze algorithmic personalization on other platforms such as Twitter and Google; 4) the design and organization of data literacy modules on algorithmic personalization, and 5) the launch of a consultancy service to promote tool take-up and the future sustainability of the project.
Summary
Personalization algorithms—filtering content on the basis of someone's profile—increasingly mediate the web experience of users. By forging a specific reality for each individual, they silently shape customized 'information diets': in other words, they determine which news, opinions and rumors users are exposed to. Restricting users’ possibilities, they ultimately infringe on their agency. As exposed by the recent Cambridge Analytica scandal, they are supported by questionable data sharing practices at the core of the business models of the social media industry. Yet, personalization algorithms are proprietary and thus remain inaccessible to end users. The few experiments auditing these algorithms rely on data provided by platform companies themselves. They are highly technical, hardly scalable, and fail to put social media users in the driver seat. The ALgorithms EXposed (ALEX) project aims at unmasking the functioning of personalization algorithms on social media platforms, taking Facebook as a test case. It is 'data activism' in practice, as it uses publicly available data for awareness raising and citizen empowerment. ALEX will pursue five goals: 1) software development and stabilization, building on the alpha version of facebook.tracking.exposed (fbtrex), a working prototype of a browser extension analyzing the outcomes of Facebook's News Feed algorithms; 2) the release of two spin-off products building on fbtrex, namely AudIT, enabling researchers to do expert analysis on algorithmic biases, and RealityCheck, allowing users to monitor their own social media consumption patterns; 3) testing the technical feasibility of adapting the ALEX approach to analyze algorithmic personalization on other platforms such as Twitter and Google; 4) the design and organization of data literacy modules on algorithmic personalization, and 5) the launch of a consultancy service to promote tool take-up and the future sustainability of the project.
Max ERC Funding
149 922 €
Duration
Start date: 2018-12-01, End date: 2020-02-29
Project acronym AMADEUS
Project Advancing CO2 Capture Materials by Atomic Scale Design: the Quest for Understanding
Researcher (PI) Christoph Rüdiger MÜLLER
Host Institution (HI) EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Call Details Consolidator Grant (CoG), PE8, ERC-2018-COG
Summary Carbon dioxide capture and storage is a technology to mitigate climate change by removing CO2 from flue gas streams or the atmosphere and storing it in geological formations. While CO2 removal from natural gas by amine scrubbing is implemented on the large scale, the cost of such process is currently prohibitively expensive. Inexpensive alkali earth metal oxides (MgO and CaO) feature high theoretical CO2 uptakes, but suffer from poor cyclic stability and slow kinetics. Yet, the key objective of recent research on alkali earth metal oxide based CO2 sorbents has been the processing of inexpensive, naturally occurring CO2 sorbents, notably limestone and dolomite, to stabilize their modest CO2 uptake and to establish re-activation methods through engineering approaches. While this research demonstrated a landmark Megawatt (MW) scale viability of the process, our fundamental understanding of the underlying CO2 capture, regeneration and deactivation pathways did not improve. The latter knowledge is, however, vital for the rational design of improved, yet practical CaO and MgO sorbents. Hence this proposal is concerned with obtaining an understanding of the underlying mechanisms that control the ability of an alkali metal oxide to capture a large quantity of CO2 with a high rate, to regenerate and to operate with high cyclic stability. Achieving these aims relies on the ability to fabricate model structures and to characterize in great detail their surface chemistry, morphology, chemical composition and changes therein under reactive conditions. This makes the development of operando and in situ characterization tools an essential prerequisite. Advances in these areas shall allow achieving the overall goal of this project, viz. to formulate a roadmap to fabricate improved CO2 sorbents through their precisely engineered structure, composition and morphology.
Summary
Carbon dioxide capture and storage is a technology to mitigate climate change by removing CO2 from flue gas streams or the atmosphere and storing it in geological formations. While CO2 removal from natural gas by amine scrubbing is implemented on the large scale, the cost of such process is currently prohibitively expensive. Inexpensive alkali earth metal oxides (MgO and CaO) feature high theoretical CO2 uptakes, but suffer from poor cyclic stability and slow kinetics. Yet, the key objective of recent research on alkali earth metal oxide based CO2 sorbents has been the processing of inexpensive, naturally occurring CO2 sorbents, notably limestone and dolomite, to stabilize their modest CO2 uptake and to establish re-activation methods through engineering approaches. While this research demonstrated a landmark Megawatt (MW) scale viability of the process, our fundamental understanding of the underlying CO2 capture, regeneration and deactivation pathways did not improve. The latter knowledge is, however, vital for the rational design of improved, yet practical CaO and MgO sorbents. Hence this proposal is concerned with obtaining an understanding of the underlying mechanisms that control the ability of an alkali metal oxide to capture a large quantity of CO2 with a high rate, to regenerate and to operate with high cyclic stability. Achieving these aims relies on the ability to fabricate model structures and to characterize in great detail their surface chemistry, morphology, chemical composition and changes therein under reactive conditions. This makes the development of operando and in situ characterization tools an essential prerequisite. Advances in these areas shall allow achieving the overall goal of this project, viz. to formulate a roadmap to fabricate improved CO2 sorbents through their precisely engineered structure, composition and morphology.
Max ERC Funding
1 994 900 €
Duration
Start date: 2019-06-01, End date: 2024-05-31
Project acronym AncientAdhesives
Project Ancient Adhesives - A window on prehistoric technological complexity
Researcher (PI) Geeske LANGEJANS
Host Institution (HI) TECHNISCHE UNIVERSITEIT DELFT
Call Details Starting Grant (StG), SH6, ERC-2018-STG
Summary AncientAdhesives addresses the most crucial problem in Palaeolithic archaeology: How to reliably infer cognitively complex behaviour in the deep past. To study the evolution of Neandertal and modern human cognitive capacities, certain find categories are taken to reflect behavioural and thus cognitive complexitye.g. Among these are art objects, personal ornaments and complex technology. Of these technology is best-suited to trace changing behavioural complexity, because 1) it is the least vulnerable to differential preservation, and 2) technological behaviours are present throughout the history of our genus. Adhesives are the oldest examples of highly complex technology. They are also known earlier from Neandertal than from modern human contexts. Understanding their technological complexity is thus essential to resolve debates on differences in cognitive complexity of both species. However, currently, there is no agreed-upon method to measure technological complexity.
The aim of AncientAdhesives is to create the first reliable method to compare the complexity of Neandertal and modern human technologies. This is achieved through three main objectives:
1. Collate the first comprehensive body of knowledge on adhesives, including ethnography, archaeology and (experimental) material properties (e.g. preservation, production).
2. Develop a new archaeological methodology by modifying industrial process modelling for archaeological applications.
3. Evaluate the development of adhesive technological complexity through time and across species using a range of explicit complexity measures.
By analysing adhesives, it is possible to measure technological complexity, to identify idiosyncratic behaviours and to track adoption and loss of complex technological know-how. This represents a step-change in debates about the development of behavioural complexity and differences/similarities between Neanderthals and modern humans.
Summary
AncientAdhesives addresses the most crucial problem in Palaeolithic archaeology: How to reliably infer cognitively complex behaviour in the deep past. To study the evolution of Neandertal and modern human cognitive capacities, certain find categories are taken to reflect behavioural and thus cognitive complexitye.g. Among these are art objects, personal ornaments and complex technology. Of these technology is best-suited to trace changing behavioural complexity, because 1) it is the least vulnerable to differential preservation, and 2) technological behaviours are present throughout the history of our genus. Adhesives are the oldest examples of highly complex technology. They are also known earlier from Neandertal than from modern human contexts. Understanding their technological complexity is thus essential to resolve debates on differences in cognitive complexity of both species. However, currently, there is no agreed-upon method to measure technological complexity.
The aim of AncientAdhesives is to create the first reliable method to compare the complexity of Neandertal and modern human technologies. This is achieved through three main objectives:
1. Collate the first comprehensive body of knowledge on adhesives, including ethnography, archaeology and (experimental) material properties (e.g. preservation, production).
2. Develop a new archaeological methodology by modifying industrial process modelling for archaeological applications.
3. Evaluate the development of adhesive technological complexity through time and across species using a range of explicit complexity measures.
By analysing adhesives, it is possible to measure technological complexity, to identify idiosyncratic behaviours and to track adoption and loss of complex technological know-how. This represents a step-change in debates about the development of behavioural complexity and differences/similarities between Neanderthals and modern humans.
Max ERC Funding
1 499 926 €
Duration
Start date: 2019-02-01, End date: 2024-01-31
Project acronym ANGULON
Project Angulon: physics and applications of a new quasiparticle
Researcher (PI) Mikhail Lemeshko
Host Institution (HI) INSTITUTE OF SCIENCE AND TECHNOLOGYAUSTRIA
Call Details Starting Grant (StG), PE3, ERC-2018-STG
Summary This project aims to develop a universal approach to angular momentum in quantum many-body systems based on the angulon quasiparticle recently discovered by the PI. We will establish a general theory of angulons in and out of equilibrium, and apply it to a variety of experimentally studied problems, ranging from chemical dynamics in solvents to solid-state systems (e.g. angular momentum transfer in the Einstein-de Haas effect and ultrafast magnetism).
The concept of angular momentum is ubiquitous across physics, whether one deals with nuclear collisions, chemical reactions, or formation of galaxies. In the microscopic world, quantum rotations are described by non-commuting operators. This makes the angular momentum theory extremely involved, even for systems consisting of only a few interacting particles, such as gas-phase atoms or molecules.
Furthermore, in most experiments the behavior of quantum particles is inevitably altered by a many-body environment of some kind. For example, molecular rotation – and therefore reactivity – depends on the presence of a solvent, electronic angular momentum in solids is coupled to lattice phonons, highly excited atomic levels can be perturbed by a surrounding ultracold gas. If approached in a brute-force fashion, understanding angular momentum in such systems is an impossible task, since a macroscopic number of particles is involved.
Recently, the PI and his team have shown that this challenge can be met by introducing a new quasiparticle – the angulon. In 2017, the PI has demonstrated the existence of angulons by comparing his theory with 20 years of measurements on molecules rotating in superfluids. Most importantly, the angulon concept allows one to gain analytical insights inaccessible to the state-of-the-art techniques of condensed matter and chemical physics. The angulon approach holds the promise of opening up a new interdisciplinary research area with applications reaching far beyond what is proposed here.
Summary
This project aims to develop a universal approach to angular momentum in quantum many-body systems based on the angulon quasiparticle recently discovered by the PI. We will establish a general theory of angulons in and out of equilibrium, and apply it to a variety of experimentally studied problems, ranging from chemical dynamics in solvents to solid-state systems (e.g. angular momentum transfer in the Einstein-de Haas effect and ultrafast magnetism).
The concept of angular momentum is ubiquitous across physics, whether one deals with nuclear collisions, chemical reactions, or formation of galaxies. In the microscopic world, quantum rotations are described by non-commuting operators. This makes the angular momentum theory extremely involved, even for systems consisting of only a few interacting particles, such as gas-phase atoms or molecules.
Furthermore, in most experiments the behavior of quantum particles is inevitably altered by a many-body environment of some kind. For example, molecular rotation – and therefore reactivity – depends on the presence of a solvent, electronic angular momentum in solids is coupled to lattice phonons, highly excited atomic levels can be perturbed by a surrounding ultracold gas. If approached in a brute-force fashion, understanding angular momentum in such systems is an impossible task, since a macroscopic number of particles is involved.
Recently, the PI and his team have shown that this challenge can be met by introducing a new quasiparticle – the angulon. In 2017, the PI has demonstrated the existence of angulons by comparing his theory with 20 years of measurements on molecules rotating in superfluids. Most importantly, the angulon concept allows one to gain analytical insights inaccessible to the state-of-the-art techniques of condensed matter and chemical physics. The angulon approach holds the promise of opening up a new interdisciplinary research area with applications reaching far beyond what is proposed here.
Max ERC Funding
1 499 588 €
Duration
Start date: 2019-02-01, End date: 2024-01-31
Project acronym ANTHROPOID
Project Great ape organoids to reconstruct uniquely human development
Researcher (PI) Jarrett CAMP
Host Institution (HI) INSTITUT FUR MOLEKULARE UND KLINISCHE OPHTHALMOLOGIE BASEL
Call Details Starting Grant (StG), LS2, ERC-2018-STG
Summary Humans diverged from our closest living relatives, chimpanzees and other great apes, 6-10 million years ago. Since this divergence, our ancestors acquired genetic changes that enhanced cognition, altered metabolism, and endowed our species with an adaptive capacity to colonize the entire planet and reshape the biosphere. Through genome comparisons between modern humans, Neandertals, chimpanzees and other apes we have identified genetic changes that likely contribute to innovations in human metabolic and cognitive physiology. However, it has been difficult to assess the functional effects of these genetic changes due to the lack of cell culture systems that recapitulate great ape organ complexity. Human and chimpanzee pluripotent stem cells (PSCs) can self-organize into three-dimensional (3D) tissues that recapitulate the morphology, function, and genetic programs controlling organ development. Our vision is to use organoids to study the changes that set modern humans apart from our closest evolutionary relatives as well as all other organisms on the planet. In ANTHROPOID we will generate a great ape developmental cell atlas using cortex, liver, and small intestine organoids. We will use single-cell transcriptomics and chromatin accessibility to identify cell type-specific features of transcriptome divergence at cellular resolution. We will dissect enhancer evolution using single-cell genomic screens and ancestralize human cells to resurrect pre-human cellular phenotypes. ANTHROPOID utilizes quantitative and state-of-the-art methods to explore exciting high-risk questions at multiple branches of the modern human lineage. This project is a ground breaking starting point to replay evolution and tackle the ancient question of what makes us uniquely human?
Summary
Humans diverged from our closest living relatives, chimpanzees and other great apes, 6-10 million years ago. Since this divergence, our ancestors acquired genetic changes that enhanced cognition, altered metabolism, and endowed our species with an adaptive capacity to colonize the entire planet and reshape the biosphere. Through genome comparisons between modern humans, Neandertals, chimpanzees and other apes we have identified genetic changes that likely contribute to innovations in human metabolic and cognitive physiology. However, it has been difficult to assess the functional effects of these genetic changes due to the lack of cell culture systems that recapitulate great ape organ complexity. Human and chimpanzee pluripotent stem cells (PSCs) can self-organize into three-dimensional (3D) tissues that recapitulate the morphology, function, and genetic programs controlling organ development. Our vision is to use organoids to study the changes that set modern humans apart from our closest evolutionary relatives as well as all other organisms on the planet. In ANTHROPOID we will generate a great ape developmental cell atlas using cortex, liver, and small intestine organoids. We will use single-cell transcriptomics and chromatin accessibility to identify cell type-specific features of transcriptome divergence at cellular resolution. We will dissect enhancer evolution using single-cell genomic screens and ancestralize human cells to resurrect pre-human cellular phenotypes. ANTHROPOID utilizes quantitative and state-of-the-art methods to explore exciting high-risk questions at multiple branches of the modern human lineage. This project is a ground breaking starting point to replay evolution and tackle the ancient question of what makes us uniquely human?
Max ERC Funding
1 500 000 €
Duration
Start date: 2019-06-01, End date: 2024-05-31
Project acronym APOLLO
Project Advanced Signal Processing Technologies for Wireless Powered Communications
Researcher (PI) Ioannis Krikidis
Host Institution (HI) UNIVERSITY OF CYPRUS
Call Details Consolidator Grant (CoG), PE7, ERC-2018-COG
Summary Wireless power transfer (WPT), pioneered by Tesla, is an idea at least as old as radio communications. However, on the one hand, due to health concerns and the large antenna dimensions required for transmission of high energy levels, until recently WPT has been limited mostly to very short distance applications. On the other hand, recent advances in silicon technology have significantly reduced the energy needs of electronic systems, making WPT over radio waves a potential source of energy for low power devices. Although WPT through radio waves has already found various short-range applications (such as the radio-frequency identification technology, healthcare monitoring etc.), its integration as a building block in the operation of wireless communications systems is still unexploited. On the other hand, conventional radio wave based information and energy transmissions have largely been designed separately. However, many applications can benefit from simultaneous wireless information and power transfer (SWIPT).
The overall objective of the APOLLO project is to study the integration of WPT/SWIPT technology into future wireless communication systems. Compared to past and current research efforts in this area, our technical approach is deeply interdisciplinary and more comprehensive, combining the expertise of wireless communications, control theory, information theory, optimization, and electronics/microwave engineering.
The key outcomes of the project include: 1) a rigorous and complete mathematical theory for WPT/SWIPT via information/communication/control theoretic studies; 2) new physical and cross-layer mechanisms that will enable the integration of WPT/SWIPT into future communication systems; 3) new network architectures that will fully exploit potential benefits of WPT/SWIPT; and 4) development of a proof-of-concept by implementing highly-efficient and multi-band metamaterial energy harvesting sensors for SWIPT.
Summary
Wireless power transfer (WPT), pioneered by Tesla, is an idea at least as old as radio communications. However, on the one hand, due to health concerns and the large antenna dimensions required for transmission of high energy levels, until recently WPT has been limited mostly to very short distance applications. On the other hand, recent advances in silicon technology have significantly reduced the energy needs of electronic systems, making WPT over radio waves a potential source of energy for low power devices. Although WPT through radio waves has already found various short-range applications (such as the radio-frequency identification technology, healthcare monitoring etc.), its integration as a building block in the operation of wireless communications systems is still unexploited. On the other hand, conventional radio wave based information and energy transmissions have largely been designed separately. However, many applications can benefit from simultaneous wireless information and power transfer (SWIPT).
The overall objective of the APOLLO project is to study the integration of WPT/SWIPT technology into future wireless communication systems. Compared to past and current research efforts in this area, our technical approach is deeply interdisciplinary and more comprehensive, combining the expertise of wireless communications, control theory, information theory, optimization, and electronics/microwave engineering.
The key outcomes of the project include: 1) a rigorous and complete mathematical theory for WPT/SWIPT via information/communication/control theoretic studies; 2) new physical and cross-layer mechanisms that will enable the integration of WPT/SWIPT into future communication systems; 3) new network architectures that will fully exploit potential benefits of WPT/SWIPT; and 4) development of a proof-of-concept by implementing highly-efficient and multi-band metamaterial energy harvesting sensors for SWIPT.
Max ERC Funding
1 930 625 €
Duration
Start date: 2019-07-01, End date: 2024-06-30
Project acronym aQUARiUM
Project QUAntum nanophotonics in Rolled-Up Metamaterials
Researcher (PI) Humeyra CAGLAYAN
Host Institution (HI) TAMPEREEN KORKEAKOULUSAATIO SR
Call Details Starting Grant (StG), PE7, ERC-2018-STG
Summary Novel sophisticated technologies that exploit the laws of quantum physics form a cornerstone for the future well-being, economic growth and security of Europe. Here photonic devices have gained a prominent position because the absorption, emission, propagation or storage of a photon is a process that can be harnessed at a fundamental level and render more practical ways to use light for such applications. However, the interaction of light with single quantum systems under ambient conditions is typically very weak and difficult to control. Furthermore, there are quantum phenomena occurring in matter at nanometer length scales that are currently not well understood. These deficiencies have a direct and severe impact on creating a bridge between quantum physics and photonic device technologies. aQUARiUM, precisely address the issue of controlling and enhancing the interaction between few photons and rolled-up nanostructures with ability to be deployed in practical applications.
With aQUARiUM, we will take epsilon (permittivity)-near-zero (ENZ) metamaterials into quantum nanophotonics. To this end, we will integrate quantum emitters with rolled-up waveguides, that act as ENZ metamaterial, to expand and redefine the range of light-matter interactions. We will explore the electromagnetic design freedom enabled by the extended modes of ENZ medium, which “stretches” the effective wavelength inside the structure. Specifically, aQUARiUM is built around the following two objectives: (i) Enhancing light-matter interactions with single emitters (Enhance) independent of emitter position. (ii) Enabling collective excitations in dense emitter ensembles (Collect) coherently connect emitters on nanophotonic devices to obtain coherent emission.
aQUARiUM aims to create novel light-sources and long-term entanglement generation and beyond. The envisioned outcome of aQUARiUM is a wholly new photonic platform applicable across a diverse range of areas.
Summary
Novel sophisticated technologies that exploit the laws of quantum physics form a cornerstone for the future well-being, economic growth and security of Europe. Here photonic devices have gained a prominent position because the absorption, emission, propagation or storage of a photon is a process that can be harnessed at a fundamental level and render more practical ways to use light for such applications. However, the interaction of light with single quantum systems under ambient conditions is typically very weak and difficult to control. Furthermore, there are quantum phenomena occurring in matter at nanometer length scales that are currently not well understood. These deficiencies have a direct and severe impact on creating a bridge between quantum physics and photonic device technologies. aQUARiUM, precisely address the issue of controlling and enhancing the interaction between few photons and rolled-up nanostructures with ability to be deployed in practical applications.
With aQUARiUM, we will take epsilon (permittivity)-near-zero (ENZ) metamaterials into quantum nanophotonics. To this end, we will integrate quantum emitters with rolled-up waveguides, that act as ENZ metamaterial, to expand and redefine the range of light-matter interactions. We will explore the electromagnetic design freedom enabled by the extended modes of ENZ medium, which “stretches” the effective wavelength inside the structure. Specifically, aQUARiUM is built around the following two objectives: (i) Enhancing light-matter interactions with single emitters (Enhance) independent of emitter position. (ii) Enabling collective excitations in dense emitter ensembles (Collect) coherently connect emitters on nanophotonic devices to obtain coherent emission.
aQUARiUM aims to create novel light-sources and long-term entanglement generation and beyond. The envisioned outcome of aQUARiUM is a wholly new photonic platform applicable across a diverse range of areas.
Max ERC Funding
1 499 431 €
Duration
Start date: 2019-01-01, End date: 2023-12-31