ERC FUNDED PROJECTS

Biofilms are antibiotic-resistant, sessile bacterial communities that occupy most moist surfaces on Earth and represent a major mode of bacterial life. Another common feature of bacterial life is exposure to viral parasites (termed phages), which are a dominant force in bacterial population control throughout nature. Surprisingly, almost nothing is known about the interactions between biofilm-dwelling bacteria and phages. This proposal is designed to fill this gap using a combination of novel methodology, experimental systems, and mathematical modeling. We have recently developed a new microscopic imaging technique that allows us to image and track all individual cells and their gene expression inside biofilms. First, we will use this technique for tracking the population dynamics of bacteria and phages within biofilms at single cell resolution. By genetically manipulating bacterial hosts and their phages, and by varying environmental conditions, we will investigate the fundamental biological and physical determinants of phage spread within biofilm communities. Second, we will study how biofilms respond to phage attack on both intra-generational and evolutionary time scales, focusing in particular on proximate response mechanisms and the population dynamics of phage-resistant and phage-susceptible cells as a function of biofilm spatial structure. Lastly, we will combine our novel insights to engineer phages that manipulate the composition of biofilm communities, either by subtraction of particular bacterial species or by addition of novel phenotypes to existing biofilm community members. Altogether, the proposed research promises to uncover the major mechanistic and evolutionary elements of biofilm-phage interactions. This combined work will greatly enrich our knowledge of microbial ecology and motivate novel strategies for bacterial biofilm control, an increasingly urgent priority in light of widespread antibiotic resistance.

1 494 963 €

Start date: 2017-01-01, End date: 2021-12-31

EMTECH analyzes the relationship between aesthetic works on human-robot interaction in Japan and cutting-edge advances in robotics and artificial intelligence. Its central hypothesis argues that a tradition of literary, artistic, and other media forms of cultural production on human-robot relationships particular to Japan is currently being built into emotionally-intelligent companion robots with the ability to understand, record, and elicit emotions in its users, consequently expanding the capacities for humans to create affective bonds with machines and transforming structures of intimacy that sustain traditional social institutions. In its most ambitious claim, EMTECH argues that this cultural tradition has played a primary role in inspiring the recently-emerging mass production of domestic robots with technology that can register and record facial expressions, heart rate, skin conductance, and other signs of affect not consciously recognized by humans, thus generating new kinds of scientific data on human affect that fundamentally challenges previous understandings of emotion. Through the textual analysis of literary work on robot imaginaries and ethnographic fieldwork on human-robot interaction in homes, palliative care centers, and engineering laboratories, EMTECH’s purpose is to collect qualitative data on new technologies of emotion management in order to advance literary and cultural theory’s contributions to the affective sciences, as well as to inform public discussions on issues of data collection, privacy, and other ethical concerns raised by the adoption of emotionally-intelligent robots in the home. Leveraging research in the humanities to critique emotional models employed by robotics engineers and designers, and implementing novel research methods such as the use of robots in both literary critique and ethnographic fieldwork, EMTECH promises to yield groundbreaking data of both theoretical and methodological application across the human sciences.

1 489 919 €

Start date: 2017-08-01, End date: 2022-07-31

This project concerns the creative agency of religious minorities in the transformation of Central and Eastern Europe societies in the 20th century. It constitutes the first comparative research on the secret police archives in the region from the perspective of the history and anthropology of religion and offers a radical perspectival shift on the value and uses of the secret police archives away from questions of justice and truth to questions of creative agency and cultural patrimony. Interdisciplinary in nature it combines archival, anthropological and cultural studies approaches to provide a re-examination and re-contextualization of the holdings of secret police archives in three states; Romania, Moldova and Hungary. The secret police archives, in addition to containing millions of files on individuals monitored by the state, also constitute a hidden repository of confiscated religious art and publications of religious minorities that were persecuted in the 20th century under fascism and communism. The investigation of these materials will be complemented by ethnographic research and the impact of the research will be extended through a public exhibition of previously hidden materials. The project has three principal stages: 1) copy/retrieve and catalogue examples of this creative material from the archives; 2) engage in ethnographic research with the communities that produced this material in order to explore the meaning and power of these artistic creations at the time of their production and in the context of post-socialism; 3) curate and stage a touring exhibition that re-presents the narratives and experiences of religious groups through their own artistic creations in order to conduct research in real time on questions of religious pluralism and intolerance in contemporary society. Through these three steps, this project will shed fresh light on the role that minority religious groups played in challenging the hegemonic order and in extending pluralism.

990 087 €

Start date: 2016-09-01, End date: 2020-08-31

LISTLIT investigates the cultural practice of lists and list making and its manifestations in narrative texts from antiquity until the twenty-first century. The simple form of the list has been remarkably constant for centuries: as a practical device, lists have been a prime instrument for classifying, organizing, and categorizing the world since the early high civilizations. Lists are tools of the mind: in visualizing human beings’ thinking, they are indicative of cognitive processes. In literary texts, list structures have been employed at least since antiquity. The manifold configurations of lists in literature and their enmeshment with the practical usage of lists in a given period take centre stage in this project. How are lists as a tool for thinking and organizing the world in everyday life and lists in literature intertwined? Embedded in narrative texts, lists challenge the received parameters of how narrative texts work. The study of lists in the trajectory of cognition, narration, and practical usage thus provides a risky and challenging alternative approach to narrative forms and functions, reader engagement, and the aesthetics of literature. Situated at the heart of the intersections between cognitive theory, cultural history, and literary history, LISTLIT significantly advances our understanding of how literature and list making as a cognitive tool and cultural practice are interrelated. By scrutinizing the practices of list writing in and beyond literary texts, LISTLIT establishes a ‘listology’, that is, the systematic and diachronic study of lists and listing structures in cultural productions.

1 382 500 €

Start date: 2017-04-01, End date: 2022-03-31