Project acronym MULTISCALECHEMBIO
Project Electronic Structure of Chemical, Biochemical, and Biophysical Systems: Multiscale Approach with Electron Correlation
Researcher (PI) Leonardo Guidoni
Host Institution (HI) UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA
Call Details Starting Grant (StG), PE4, ERC-2009-StG
Summary The currently available computational methods have often serious limitations to treat systems where electron correlation plays and important role. Many issues concerning the electronic structure of radicals, photoreceptors near-half-filled transition metals (Cr,Mo,Fe,Ni) are of paramount relevance in basic and applied research in Chemistry and Biochemistry, but still out of the capabilities of standard and conventional tools such as Density Functional Theory. On the other hand, post Hartree-Fock methods computationally more expensive and their application is limited to few atoms. The objective of the present proposal is to overcome these limitations and to develop and apply a multiscale, innovative and unconventional computer simulation technique to unravel the electronic properties of strongly correlated chemical and biochemical systems. The methodology is based on a combined approach between Quantum Monte Carlo (QMC), DFT and Molecular Mechanics. The proposed approach has a faster scaling of the calculation time with the system size N with respect others standard quantum chemistry methods of equivalent level (~ N4 vs ~ N7). es to address challenging open problems in the chemistry and biochemistry of radical compounds, photoreceptors, and transition metal catalysis and enzymatic activity. Application to photoreceptors include the study of the spectral properties of rhodopsin, the integral membrane protein responsible of the light detection in the retina. Applications on transition metal molecules will shed the light on the catalytic strategies of iron-based enzymes and their corresponding biomimetic compounds.
Summary
The currently available computational methods have often serious limitations to treat systems where electron correlation plays and important role. Many issues concerning the electronic structure of radicals, photoreceptors near-half-filled transition metals (Cr,Mo,Fe,Ni) are of paramount relevance in basic and applied research in Chemistry and Biochemistry, but still out of the capabilities of standard and conventional tools such as Density Functional Theory. On the other hand, post Hartree-Fock methods computationally more expensive and their application is limited to few atoms. The objective of the present proposal is to overcome these limitations and to develop and apply a multiscale, innovative and unconventional computer simulation technique to unravel the electronic properties of strongly correlated chemical and biochemical systems. The methodology is based on a combined approach between Quantum Monte Carlo (QMC), DFT and Molecular Mechanics. The proposed approach has a faster scaling of the calculation time with the system size N with respect others standard quantum chemistry methods of equivalent level (~ N4 vs ~ N7). es to address challenging open problems in the chemistry and biochemistry of radical compounds, photoreceptors, and transition metal catalysis and enzymatic activity. Application to photoreceptors include the study of the spectral properties of rhodopsin, the integral membrane protein responsible of the light detection in the retina. Applications on transition metal molecules will shed the light on the catalytic strategies of iron-based enzymes and their corresponding biomimetic compounds.
Max ERC Funding
1 200 000 €
Duration
Start date: 2009-10-01, End date: 2015-09-30
Project acronym NANO-ARCH
Project Assembly of Colloidal Nanocrystals into Unconventional Types of Nanocomposite Architectures with Advanced Properties
Researcher (PI) Liberato Manna
Host Institution (HI) FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Call Details Starting Grant (StG), PE5, ERC-2009-StG
Summary Nanoscience promises innovative solutions in a large variety of sectors, ranging from cost-effective optoelectronic devices to energy generation, and to highly performing materials and interfaces. Realizing this promise will rely heavily on a bottom-up approach. This can only succeed if self assembly of advanced nanoscale building blocks will be developed intensively, to enable creation of useful macroscopic architectures. The unconventional assembly of nanocrystals towards functional materials is the area where this proposal aims at providing a key contribution. This will be achieved via ground-breaking advances in the fabrication of shape controlled nanocrystals, via solution approaches, in their organization following radically new concepts and in the study of their assembly related properties. The bottom line here is to tune the assembly process of nanocrystals so as to generate a desired functionality or a combination of functionalities. This would represent a dramatic leap forward from the trial-and-error approach to controlling the various properties that is currently prevalent in many of the communities working in the field of nanocrystals. The primary motivation of this proposal is therefore to correlate strongly the structural properties with the behaviour of nanostructured assemblies. This is clearly a cutting edge research program, at the frontier of chemistry, physics, materials science and engineering, and whose successful outcome will be of tremendous benefit in several fields.
Summary
Nanoscience promises innovative solutions in a large variety of sectors, ranging from cost-effective optoelectronic devices to energy generation, and to highly performing materials and interfaces. Realizing this promise will rely heavily on a bottom-up approach. This can only succeed if self assembly of advanced nanoscale building blocks will be developed intensively, to enable creation of useful macroscopic architectures. The unconventional assembly of nanocrystals towards functional materials is the area where this proposal aims at providing a key contribution. This will be achieved via ground-breaking advances in the fabrication of shape controlled nanocrystals, via solution approaches, in their organization following radically new concepts and in the study of their assembly related properties. The bottom line here is to tune the assembly process of nanocrystals so as to generate a desired functionality or a combination of functionalities. This would represent a dramatic leap forward from the trial-and-error approach to controlling the various properties that is currently prevalent in many of the communities working in the field of nanocrystals. The primary motivation of this proposal is therefore to correlate strongly the structural properties with the behaviour of nanostructured assemblies. This is clearly a cutting edge research program, at the frontier of chemistry, physics, materials science and engineering, and whose successful outcome will be of tremendous benefit in several fields.
Max ERC Funding
1 299 960 €
Duration
Start date: 2009-11-01, End date: 2013-10-31
Project acronym NANOCONTACTS
Project Structural and electronic properties of nanoscale metallic contacts fabricated by thermally assisted electromigration
Researcher (PI) Regina Hoffmann-Vogel
Host Institution (HI) KARLSRUHER INSTITUT FUER TECHNOLOGIE
Call Details Starting Grant (StG), PE3, ERC-2009-StG
Summary The key aim of the project is to correlate the electronic transport properties of nanoscale metallic contacts with their structure. The electronic transport properties through a metallic contact of atomic dimensions are governed by the atomic structure and by the chemical properties of the contact as well as by the wave nature of electrons. This leads to plateaus of the conductance measured as a function of contact size that do not necessarily correspond to integer multiples of the conductance quantum. I will investigate whether and how atomic as well as electronic shell effects influence the atomic structure of nanoscale metallic contacts. We will measure both electronic transport properties and structural properties concurrently and determine their mutual relation on each individual contact. The contacts will be fabricated by Joule heating a nanowire until thermally assisted electromigration sets in and thins the nanowire to form a contact. The structural properties of these nanocontacts will be studied using scanning force microscopy and scanning tunneling microscopy with atomic resolution in ultrahigh-vacuum. This approach will allow us to use clean superconducting contacts and to exploit superconductivity in order to study the electronic transport properties of the contacts. The electronic transport properties will be studied employing multiple Andreev reflections to determine the number and transmission coefficient of electronic conduction channels. Eventually, a deeper understanding of the relation between structure and electronic transport properties will be obtained which is a prerequisite to tailor the electronic transport properties of nanoscale metallic contacts.
Summary
The key aim of the project is to correlate the electronic transport properties of nanoscale metallic contacts with their structure. The electronic transport properties through a metallic contact of atomic dimensions are governed by the atomic structure and by the chemical properties of the contact as well as by the wave nature of electrons. This leads to plateaus of the conductance measured as a function of contact size that do not necessarily correspond to integer multiples of the conductance quantum. I will investigate whether and how atomic as well as electronic shell effects influence the atomic structure of nanoscale metallic contacts. We will measure both electronic transport properties and structural properties concurrently and determine their mutual relation on each individual contact. The contacts will be fabricated by Joule heating a nanowire until thermally assisted electromigration sets in and thins the nanowire to form a contact. The structural properties of these nanocontacts will be studied using scanning force microscopy and scanning tunneling microscopy with atomic resolution in ultrahigh-vacuum. This approach will allow us to use clean superconducting contacts and to exploit superconductivity in order to study the electronic transport properties of the contacts. The electronic transport properties will be studied employing multiple Andreev reflections to determine the number and transmission coefficient of electronic conduction channels. Eventually, a deeper understanding of the relation between structure and electronic transport properties will be obtained which is a prerequisite to tailor the electronic transport properties of nanoscale metallic contacts.
Max ERC Funding
1 513 000 €
Duration
Start date: 2010-01-01, End date: 2015-12-31
Project acronym NEUROMAN
Project Identifying the genes responsible for the expansion of the human cerebral cortex
Researcher (PI) Wieland Bernhard Huttner
Host Institution (HI) MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Call Details Advanced Grant (AdG), LS5, ERC-2009-AdG
Summary The goal of this research proposal is to unravel the molecular and cell biological basis underlying the expansion of the human cerebral cortex. Specifically, we wish to identify the genes responsible for the increase in the generation of cortical neurons from neural stem and progenitor cells that occurs during primate evolution. We will take two complementary approaches. One is to characterize the differences between mouse and human cerebral cortex with regard to the molecular and cell biological features of neural stem and progenitor cells, their mode of division, and the generation of neurons from these cells. Among the observed differences, human-specific features of cortical progenitor cells will then be identified by comparison with various non-human primates. The resulting candidate genes will be expressed in mouse embryonic cortical progenitors by in utero electroporation and tested for their ability to reconstitute human-like cortical progenitors in vivo. The second approach is based on a novel technology that allows us to introduce the total pool of mRNAs expressed in human cortical progenitors into mouse cortical progenitors in organotypic slice culture. This technology will be used to functionally screen for human genes able to generate human-like cortical progenitors in the mouse embryonic cortex. Human genes validated by these two approaches will then be used to generate acute transgenic mouse embryos and transgenic mouse lines that show a gyrencephalic, primate-like cerebral cortex. This research proposal will provide fundamental insight into the process of human cortical expansion, which provides the cellular basis of higher brain function, and establish an essential basis for future progenitor cell-based therapies for the diseased human brain.
Summary
The goal of this research proposal is to unravel the molecular and cell biological basis underlying the expansion of the human cerebral cortex. Specifically, we wish to identify the genes responsible for the increase in the generation of cortical neurons from neural stem and progenitor cells that occurs during primate evolution. We will take two complementary approaches. One is to characterize the differences between mouse and human cerebral cortex with regard to the molecular and cell biological features of neural stem and progenitor cells, their mode of division, and the generation of neurons from these cells. Among the observed differences, human-specific features of cortical progenitor cells will then be identified by comparison with various non-human primates. The resulting candidate genes will be expressed in mouse embryonic cortical progenitors by in utero electroporation and tested for their ability to reconstitute human-like cortical progenitors in vivo. The second approach is based on a novel technology that allows us to introduce the total pool of mRNAs expressed in human cortical progenitors into mouse cortical progenitors in organotypic slice culture. This technology will be used to functionally screen for human genes able to generate human-like cortical progenitors in the mouse embryonic cortex. Human genes validated by these two approaches will then be used to generate acute transgenic mouse embryos and transgenic mouse lines that show a gyrencephalic, primate-like cerebral cortex. This research proposal will provide fundamental insight into the process of human cortical expansion, which provides the cellular basis of higher brain function, and establish an essential basis for future progenitor cell-based therapies for the diseased human brain.
Max ERC Funding
2 496 000 €
Duration
Start date: 2010-10-01, End date: 2016-09-30
Project acronym ODMIR
Project The origins and development of the human mirror neuron system
Researcher (PI) Chiara Turati
Host Institution (HI) UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
Call Details Starting Grant (StG), SH4, ERC-2009-StG
Summary Evidence demonstrating the presence of mirror neurons in the adult human brain has led many researchers to suggest a fundamental role for the mirror neuron system (MNS) in human mentalizing behavior and social cognition. Recent findings have also suggested strong relationships between MNS impairments and neurodevelopmental disorders in which mentalizing behavior is impaired. In light of this evidence, it has become of paramount importance to understand whether or not the MNS is present at birth and how its functional properties develop throughout infancy. The current project will address these questions within the context of a neuroconstructivist framework, according to which a basic perception-action coupling mechanism would be present from birth, and undergoes a series of refinements through experience and visuomotor learning. Using behavioral, electromyographic and electrophysiological measures, the project aims to investigate action understanding and emotion recognition in newborns and infants. Behavioral looking time and eye-movement paradigms will be used to test infants ability to visually anticipate the action s goal. Electromyographic paradigms will allow for testing of when and how the activation of infants muscles is affected by the goal of the observed action or the emotion expressed by the observed face. Electrophysiological paradigms will be used to investigate modulations of infants EEG activity during the execution and observation of grasping actions.
Summary
Evidence demonstrating the presence of mirror neurons in the adult human brain has led many researchers to suggest a fundamental role for the mirror neuron system (MNS) in human mentalizing behavior and social cognition. Recent findings have also suggested strong relationships between MNS impairments and neurodevelopmental disorders in which mentalizing behavior is impaired. In light of this evidence, it has become of paramount importance to understand whether or not the MNS is present at birth and how its functional properties develop throughout infancy. The current project will address these questions within the context of a neuroconstructivist framework, according to which a basic perception-action coupling mechanism would be present from birth, and undergoes a series of refinements through experience and visuomotor learning. Using behavioral, electromyographic and electrophysiological measures, the project aims to investigate action understanding and emotion recognition in newborns and infants. Behavioral looking time and eye-movement paradigms will be used to test infants ability to visually anticipate the action s goal. Electromyographic paradigms will allow for testing of when and how the activation of infants muscles is affected by the goal of the observed action or the emotion expressed by the observed face. Electrophysiological paradigms will be used to investigate modulations of infants EEG activity during the execution and observation of grasping actions.
Max ERC Funding
1 208 400 €
Duration
Start date: 2009-12-01, End date: 2015-05-31
Project acronym ORGENECHOICE
Project Regulation of the expression of odorant receptor genes in mouse
Researcher (PI) Peter Mombaerts
Host Institution (HI) MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Call Details Advanced Grant (AdG), LS5, ERC-2009-AdG
Summary Odorant receptor (OR) genes form the largest family in the mouse genome: ~1200 genes spread over ~40 loci. Each olfactory sensory neuron (OSN) expresses one OR gene, from one allele. The mechanisms of OR gene choice remain elusive. We will execute five specific aims that are interconnected but independent. We will search for homeodomain genes that we can link functionally to expression of a subset of OR genes; we will define promoter regions for the eight OR genes that are solitary, not belonging to a cluster; we will look for organizational principles among the repertoire of second choices in OSNs that express first an OR locus without a coding sequence; we will characterize the phenotype of mice with a knockout of a novel regulatory element, the P element; and we will test the distance-dependence of the activity of this and a similar element (the H region) by transplanting it within the local genomic region. Guiding hypotheses are that promoter regions for OR genes are short and close to the coding sequence; that the conserved homeodomain and O/E binding sites in OR promoter regions have a fundamental role in OR gene choice, rather than in transcription after it is chosen for expression; and that the H and P elements are two of several similar regulatory elements that each operate in cis within a cluster. The approach is based on gene targeting and transgenesis by pronuclear injection. A multipronged strategy will be taken to assay OR gene expression, with βgal-reporter mice, in situ hybridization, custom Affymetrix microarrays for mouse ORs, quantitative, real-time PCR, and Nanostring molecular bar codes. Understanding OR gene choice will have implications for our understanding of the regulation of gene expression in the mammalian genome – particularly if new mechanisms or principles are discovered.
Summary
Odorant receptor (OR) genes form the largest family in the mouse genome: ~1200 genes spread over ~40 loci. Each olfactory sensory neuron (OSN) expresses one OR gene, from one allele. The mechanisms of OR gene choice remain elusive. We will execute five specific aims that are interconnected but independent. We will search for homeodomain genes that we can link functionally to expression of a subset of OR genes; we will define promoter regions for the eight OR genes that are solitary, not belonging to a cluster; we will look for organizational principles among the repertoire of second choices in OSNs that express first an OR locus without a coding sequence; we will characterize the phenotype of mice with a knockout of a novel regulatory element, the P element; and we will test the distance-dependence of the activity of this and a similar element (the H region) by transplanting it within the local genomic region. Guiding hypotheses are that promoter regions for OR genes are short and close to the coding sequence; that the conserved homeodomain and O/E binding sites in OR promoter regions have a fundamental role in OR gene choice, rather than in transcription after it is chosen for expression; and that the H and P elements are two of several similar regulatory elements that each operate in cis within a cluster. The approach is based on gene targeting and transgenesis by pronuclear injection. A multipronged strategy will be taken to assay OR gene expression, with βgal-reporter mice, in situ hybridization, custom Affymetrix microarrays for mouse ORs, quantitative, real-time PCR, and Nanostring molecular bar codes. Understanding OR gene choice will have implications for our understanding of the regulation of gene expression in the mammalian genome – particularly if new mechanisms or principles are discovered.
Max ERC Funding
2 500 000 €
Duration
Start date: 2010-04-01, End date: 2015-03-31
Project acronym PECS
Project Powerful and Efficient EUV Coherent Light Sources
Researcher (PI) Jens Limpert
Host Institution (HI) FRIEDRICH-SCHILLER-UNIVERSITAT JENA
Call Details Starting Grant (StG), PE3, ERC-2009-StG
Summary The interest in and hence the need for coherent short-wavelength (EUV spectral range) laser sources is rapidly increasing. Potentially, such sources will allow for novel approaches in fundamental science, metrology, imaging, spectroscopy and might even enable new lithographic production techniques. One example is Atto-Science, one of the groundbreaking topics in physical science of the next decade. High harmonic generation (HHG) in noble gases is considered as the most suitable technique to generate spatially coherent EUV light. Unfortunately, the conversion efficiency of HHG is rather small. Furthermore, conventional ultra-short pulse laser sources required for HHG are limited in average power due to thermo-optical problems, therefore, the resulting EUV radiation is characterized by an extremely low number of photons per unit time (average power). Consequently, all the applications of EUV radiation suffer from the lack of powerful coherent light sources in this interesting spectral range, which results extremely long integration or processing times. Ultimately this lack of power make current EUV sources be considered as laboratory curiosities without any relevance for real world applications. The goal of the proposed project is to investigate novel methods to increase the efficiency and the average output power of HHG based EUV light sources. Of outmost importance is the development of efficient, compact and powerful (>3 kW average power) high peak power (>100 MW) ultra-short pulse (<200 fs) laser systems to drive the HHG process. Fiber based amplifiers have the potential to fulfil this parameter range in a compact und ultra-stable manner allowing the generation of EUV radiation outside a specially protected laboratory environment. In summary, the goal of the proposed project is the development of efficient and powerful tailored, meaning application-oriented, EUV light sources.
Summary
The interest in and hence the need for coherent short-wavelength (EUV spectral range) laser sources is rapidly increasing. Potentially, such sources will allow for novel approaches in fundamental science, metrology, imaging, spectroscopy and might even enable new lithographic production techniques. One example is Atto-Science, one of the groundbreaking topics in physical science of the next decade. High harmonic generation (HHG) in noble gases is considered as the most suitable technique to generate spatially coherent EUV light. Unfortunately, the conversion efficiency of HHG is rather small. Furthermore, conventional ultra-short pulse laser sources required for HHG are limited in average power due to thermo-optical problems, therefore, the resulting EUV radiation is characterized by an extremely low number of photons per unit time (average power). Consequently, all the applications of EUV radiation suffer from the lack of powerful coherent light sources in this interesting spectral range, which results extremely long integration or processing times. Ultimately this lack of power make current EUV sources be considered as laboratory curiosities without any relevance for real world applications. The goal of the proposed project is to investigate novel methods to increase the efficiency and the average output power of HHG based EUV light sources. Of outmost importance is the development of efficient, compact and powerful (>3 kW average power) high peak power (>100 MW) ultra-short pulse (<200 fs) laser systems to drive the HHG process. Fiber based amplifiers have the potential to fulfil this parameter range in a compact und ultra-stable manner allowing the generation of EUV radiation outside a specially protected laboratory environment. In summary, the goal of the proposed project is the development of efficient and powerful tailored, meaning application-oriented, EUV light sources.
Max ERC Funding
1 450 000 €
Duration
Start date: 2009-11-01, End date: 2013-10-31
Project acronym PHODIR
Project PHOtonic-based full DIgital Radar
Researcher (PI) Antonella Bogoni
Host Institution (HI) CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI
Call Details Starting Grant (StG), PE7, ERC-2009-StG
Summary PHODIR project aims to study, design and realize a full digital transceiver radar demonstrator based on photonic technology both for signal generation and for RF received signal processing. Hybrid technologies merging second generation optical systems and conventional radar architecture could be the answer to issues deriving from electronic devices poor performances such high SFDR (Spurious Free Dynamic Range) and high phase noise level that are nowadays impeding the construction of a fully digital radar transceiver. Starting from a conventional radar architecture, the generation of high frequency signals in the optical domain at the transmitter section and the use of ultra-high bit rate and short width optical pulse train for RF received signal sampling are the main solutions we are going to investigate in the project to overcome problems related to electronic devices. The innovative research aspects of the proposal are: -Definition of a new full digital radar transceiver architecture based on photonic technology -Development and realization of new electro-optic second generation devices -New parallel signal processing algorithms. The most important benefits arising from the project are: -Electro-optic system integration -New technological development in the design of advanced photonic devices -New technological/scientific development in the design of high performance radar CNIT can provide an high level of experience in the field of photonic devices design and implementation and radar system analysis and design. Theoretical support and experimental test-bed thanks to instrumentations and competences in very high-bit rate Gb/s Optical Time Division Multiplexing Systems and techniques for ultra-fast optical sampling are also provided by CNIT.
Summary
PHODIR project aims to study, design and realize a full digital transceiver radar demonstrator based on photonic technology both for signal generation and for RF received signal processing. Hybrid technologies merging second generation optical systems and conventional radar architecture could be the answer to issues deriving from electronic devices poor performances such high SFDR (Spurious Free Dynamic Range) and high phase noise level that are nowadays impeding the construction of a fully digital radar transceiver. Starting from a conventional radar architecture, the generation of high frequency signals in the optical domain at the transmitter section and the use of ultra-high bit rate and short width optical pulse train for RF received signal sampling are the main solutions we are going to investigate in the project to overcome problems related to electronic devices. The innovative research aspects of the proposal are: -Definition of a new full digital radar transceiver architecture based on photonic technology -Development and realization of new electro-optic second generation devices -New parallel signal processing algorithms. The most important benefits arising from the project are: -Electro-optic system integration -New technological development in the design of advanced photonic devices -New technological/scientific development in the design of high performance radar CNIT can provide an high level of experience in the field of photonic devices design and implementation and radar system analysis and design. Theoretical support and experimental test-bed thanks to instrumentations and competences in very high-bit rate Gb/s Optical Time Division Multiplexing Systems and techniques for ultra-fast optical sampling are also provided by CNIT.
Max ERC Funding
1 600 000 €
Duration
Start date: 2009-12-01, End date: 2013-11-30
Project acronym POLPBAR
Project Production of Polarized Antiprotons
Researcher (PI) Hans Ströher
Host Institution (HI) FORSCHUNGSZENTRUM JULICH GMBH
Call Details Advanced Grant (AdG), PE2, ERC-2009-AdG
Summary Hadrons, the building blocks of all matter in Nature, are not fundamental but composed of quarks and gluons. Up to now we do not know HOW NATURE MAKES HADRONS one of the most important questions of contemporary structure-of-matter physics. Major breakthroughs are to be expected with new experimental facilities such as FAIR. Most studies in hadron physics at HESR/FAIR will employ beams of unpolarized antiprotons, but the most spectacular opportunities will arise for polarized antiprotons the physics case is exceptional. The flag-ship experiment, Drell-Yan production in double polarized proton-antiproton scattering, gives direct access to transversity , the terra incognita of nucleon spin structure. The provision of such beams presents enormous scientific / technological challenges and has never been achieved with intensities sufficient for the crucial experiments. State-of-the-art techniques are capable of producing intensities less than ~10^5 s-1, which cannot be efficiently accumulated. It is the aim of this project to develop an efficient method for POLARIZING ANTIPROTON BEAMS by in-situ build-up in a storage ring. The only viable method to do this effectively is through "spin-filtering" by the repeated interaction of an antiproton beam with a polarized hydrogen gas target in a cooler storage ring. This technique works with protons, but it is not clear how the polarization build-up happens in detail. Spin-filtering needs to be optimized and, in particular, it must be extended to antiprotons. Within the framework of this project, the aim is to provide polarized antiproton beams in a storage ring with at least WITH 10 ORDERS OF MAGNITUDE higher intensity than previously possible. A very experienced team of scientists and engineers is needed, and this is available within my group. We will also strongly benefit from our collaboration partners. Thus, it is a "now or never" opportunity. If successful, a new era will open with fascinating experiments.
Summary
Hadrons, the building blocks of all matter in Nature, are not fundamental but composed of quarks and gluons. Up to now we do not know HOW NATURE MAKES HADRONS one of the most important questions of contemporary structure-of-matter physics. Major breakthroughs are to be expected with new experimental facilities such as FAIR. Most studies in hadron physics at HESR/FAIR will employ beams of unpolarized antiprotons, but the most spectacular opportunities will arise for polarized antiprotons the physics case is exceptional. The flag-ship experiment, Drell-Yan production in double polarized proton-antiproton scattering, gives direct access to transversity , the terra incognita of nucleon spin structure. The provision of such beams presents enormous scientific / technological challenges and has never been achieved with intensities sufficient for the crucial experiments. State-of-the-art techniques are capable of producing intensities less than ~10^5 s-1, which cannot be efficiently accumulated. It is the aim of this project to develop an efficient method for POLARIZING ANTIPROTON BEAMS by in-situ build-up in a storage ring. The only viable method to do this effectively is through "spin-filtering" by the repeated interaction of an antiproton beam with a polarized hydrogen gas target in a cooler storage ring. This technique works with protons, but it is not clear how the polarization build-up happens in detail. Spin-filtering needs to be optimized and, in particular, it must be extended to antiprotons. Within the framework of this project, the aim is to provide polarized antiproton beams in a storage ring with at least WITH 10 ORDERS OF MAGNITUDE higher intensity than previously possible. A very experienced team of scientists and engineers is needed, and this is available within my group. We will also strongly benefit from our collaboration partners. Thus, it is a "now or never" opportunity. If successful, a new era will open with fascinating experiments.
Max ERC Funding
2 448 376 €
Duration
Start date: 2010-05-01, End date: 2016-04-30
Project acronym POLYCAT
Project Polymeric catalysts and supports: A new paradigm for biomass processing
Researcher (PI) Franz Ferdinand Schüth
Host Institution (HI) MAX PLANCK INSTITUT FUER KOHLENFORSCHUNG
Call Details Advanced Grant (AdG), PE5, ERC-2009-AdG
Summary Transforming part of the feedstock base of the chemical industry from fossil feedstocks to biomass, as expected by many researchers and companies, requires fundamental changes in the technologies for processing. While fossil feedstocks are non-polar and processed at high temperatures in the gas phase, most biomass derived feedstocks are polar molecules, which are present in aqueous solution and are typically processed at relatively low temperatures in defunctionalization reactions. Yet, most approaches rely on the conventional wisdom of using catalysts developed for fossil feed processing where the conditions almost always exclude the use of polymeric catalysts. However, for the conditions of biomass processing, adapted polymeric catalysts could be ideally suited. This defines the goals of the proposed research program: known and newly designed polymeric catalysts will be explored with respect to their potential in biomass conversion reactions, which could lead to a new paradigm in catalytic biofeedstock processing. In order to achieve this objective, it will be attempted to produce four selected, exemplary classes of polymers in porous form with adjustable porosity. The porous polymer types will then be post-treated with different methods to introduce catalytic functionality (acid/base and redox functionality). The target processes in biomass conversion are prototypical examples which are representative for whole classes of reactions. These include the depolymerisation of the major components of lignocellulose (cellulose, hemicellulose and lignin) and the targeted synthesis of selected platform molecules starting from glucose as the depolymerisation product of cellulose. Successful completion would provide more efficient access to many novel value chains and establish a novel class of catalytic materials.
Summary
Transforming part of the feedstock base of the chemical industry from fossil feedstocks to biomass, as expected by many researchers and companies, requires fundamental changes in the technologies for processing. While fossil feedstocks are non-polar and processed at high temperatures in the gas phase, most biomass derived feedstocks are polar molecules, which are present in aqueous solution and are typically processed at relatively low temperatures in defunctionalization reactions. Yet, most approaches rely on the conventional wisdom of using catalysts developed for fossil feed processing where the conditions almost always exclude the use of polymeric catalysts. However, for the conditions of biomass processing, adapted polymeric catalysts could be ideally suited. This defines the goals of the proposed research program: known and newly designed polymeric catalysts will be explored with respect to their potential in biomass conversion reactions, which could lead to a new paradigm in catalytic biofeedstock processing. In order to achieve this objective, it will be attempted to produce four selected, exemplary classes of polymers in porous form with adjustable porosity. The porous polymer types will then be post-treated with different methods to introduce catalytic functionality (acid/base and redox functionality). The target processes in biomass conversion are prototypical examples which are representative for whole classes of reactions. These include the depolymerisation of the major components of lignocellulose (cellulose, hemicellulose and lignin) and the targeted synthesis of selected platform molecules starting from glucose as the depolymerisation product of cellulose. Successful completion would provide more efficient access to many novel value chains and establish a novel class of catalytic materials.
Max ERC Funding
1 764 000 €
Duration
Start date: 2010-03-01, End date: 2015-02-28