Project acronym BI-DSC
Project Building Integrated Dye Sensitized Solar Cells
Researcher (PI) Adélio Miguel Magalhaes Mendes
Host Institution (HI) UNIVERSIDADE DO PORTO
Call Details Advanced Grant (AdG), PE8, ERC-2012-ADG_20120216
Summary In the last decade, solar and photovoltaic (PV) technologies have emerged as a potentially major technology for power generation in the world. So far the PV field has been dominated by silicon devices, even though this technology is still expensive.Dye-sensitized solar cells (DSC) are an important type of thin-film photovoltaics due to their potential for low-cost fabrication and versatile applications, and because their aesthetic appearance, semi-transparency and different color possibilities.This advantageous characteristic makes DSC the first choice for building integrated photovoltaics.Despite their great potential, DSCs for building applications are still not available at commercial level. However, to bring DSCs to a marketable product several developments are still needed and the present project targets to give relevant answers to three key limitations: encapsulation, glass substrate enhanced electrical conductivity and more efficient and low-cost raw-materials. Recently, the proponent successfully addressed the hermetic devices sealing by developing a laser-assisted glass sealing procedure.Thus, BI-DSC proposal envisages the development of DSC modules 30x30cm2, containing four individual cells, and their incorporation in a 1m2 double glass sheet arrangement for BIPV with an energy efficiency of at least 9% and a lifetime of 20 years. Additionally, aiming at enhanced efficiency of the final device and decreased total costs of DSCs manufacturing, new materials will be also pursued. The following inner-components were identified as critical: carbon-based counter-electrode; carbon quantum-dots and hierarchically TiO2 photoelectrode. It is then clear that this project is divided into two research though parallel directions: a fundamental research line, contributing to the development of the new generation DSC technology; while a more applied research line targets the development of a DSC functional module that can be used to pave the way for its industrialization.
Summary
In the last decade, solar and photovoltaic (PV) technologies have emerged as a potentially major technology for power generation in the world. So far the PV field has been dominated by silicon devices, even though this technology is still expensive.Dye-sensitized solar cells (DSC) are an important type of thin-film photovoltaics due to their potential for low-cost fabrication and versatile applications, and because their aesthetic appearance, semi-transparency and different color possibilities.This advantageous characteristic makes DSC the first choice for building integrated photovoltaics.Despite their great potential, DSCs for building applications are still not available at commercial level. However, to bring DSCs to a marketable product several developments are still needed and the present project targets to give relevant answers to three key limitations: encapsulation, glass substrate enhanced electrical conductivity and more efficient and low-cost raw-materials. Recently, the proponent successfully addressed the hermetic devices sealing by developing a laser-assisted glass sealing procedure.Thus, BI-DSC proposal envisages the development of DSC modules 30x30cm2, containing four individual cells, and their incorporation in a 1m2 double glass sheet arrangement for BIPV with an energy efficiency of at least 9% and a lifetime of 20 years. Additionally, aiming at enhanced efficiency of the final device and decreased total costs of DSCs manufacturing, new materials will be also pursued. The following inner-components were identified as critical: carbon-based counter-electrode; carbon quantum-dots and hierarchically TiO2 photoelectrode. It is then clear that this project is divided into two research though parallel directions: a fundamental research line, contributing to the development of the new generation DSC technology; while a more applied research line targets the development of a DSC functional module that can be used to pave the way for its industrialization.
Max ERC Funding
1 989 300 €
Duration
Start date: 2013-03-01, End date: 2018-08-31
Project acronym ComplexiTE
Project An integrated multidisciplinary tissue engineering approach combining novel high-throughput screening and advanced methodologies to create complex biomaterials-stem cells constructs
Researcher (PI) Rui Luis Gonçalves Dos Reis
Host Institution (HI) UNIVERSIDADE DO MINHO
Call Details Advanced Grant (AdG), PE8, ERC-2012-ADG_20120216
Summary New developments on tissue engineering strategies should realize the complexity of tissue remodelling and the inter-dependency of many variables associated to stem cells and biomaterials interactions. ComplexiTE proposes an integrated approach to address such multiple factors in which different innovative methodologies are implemented, aiming at developing tissue-like substitutes with enhanced in vivo functionality. Several ground-breaking advances are expected to be achieved, including: i) improved methodologies for isolation and expansion of sub-populations of stem cells derived from not so explored sources such as adipose tissue and amniotic fluid; ii) radically new methods to monitor human stem cells behaviour in vivo; iii) new macromolecules isolated from renewable resources, especially from marine origin; iv) combinations of liquid volumes mingling biomaterials and distinct stem cells, generating hydrogel beads upon adequate cross-linking reactions; v) optimised culture of the produced beads in adequate 3D bioreactors and a novel selection method to sort the beads that show a (pre-defined) positive biological reading; vi) random 3D arrays validated by identifying the natural polymers and cells composing the positive beads; v) 2D arrays of selected hydrogel spots for brand new in vivo tests, in which each spot of the implanted chip may be evaluated within the living animal using adequate imaging methods; vi) new porous scaffolds of the best combinations formed by particles agglomeration or fiber-based rapid-prototyping. The ultimate goal of this proposal is to develop breakthrough research specifically focused on the above mentioned key issues and radically innovative approaches to produce and scale-up new tissue engineering strategies that are both industrially and clinically relevant, by mastering the inherent complexity associated to the correct selection among a great number of combinations of possible biomaterials, stem cells and culturing conditions.
Summary
New developments on tissue engineering strategies should realize the complexity of tissue remodelling and the inter-dependency of many variables associated to stem cells and biomaterials interactions. ComplexiTE proposes an integrated approach to address such multiple factors in which different innovative methodologies are implemented, aiming at developing tissue-like substitutes with enhanced in vivo functionality. Several ground-breaking advances are expected to be achieved, including: i) improved methodologies for isolation and expansion of sub-populations of stem cells derived from not so explored sources such as adipose tissue and amniotic fluid; ii) radically new methods to monitor human stem cells behaviour in vivo; iii) new macromolecules isolated from renewable resources, especially from marine origin; iv) combinations of liquid volumes mingling biomaterials and distinct stem cells, generating hydrogel beads upon adequate cross-linking reactions; v) optimised culture of the produced beads in adequate 3D bioreactors and a novel selection method to sort the beads that show a (pre-defined) positive biological reading; vi) random 3D arrays validated by identifying the natural polymers and cells composing the positive beads; v) 2D arrays of selected hydrogel spots for brand new in vivo tests, in which each spot of the implanted chip may be evaluated within the living animal using adequate imaging methods; vi) new porous scaffolds of the best combinations formed by particles agglomeration or fiber-based rapid-prototyping. The ultimate goal of this proposal is to develop breakthrough research specifically focused on the above mentioned key issues and radically innovative approaches to produce and scale-up new tissue engineering strategies that are both industrially and clinically relevant, by mastering the inherent complexity associated to the correct selection among a great number of combinations of possible biomaterials, stem cells and culturing conditions.
Max ERC Funding
2 320 000 €
Duration
Start date: 2013-05-01, End date: 2018-04-30
Project acronym DEPENDABLECLOUD
Project Towards the dependable cloud:
Building the foundations for tomorrow's dependable cloud computing
Researcher (PI) Rodrigo Seromenho Miragaia Rodrigues
Host Institution (HI) INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA
Call Details Starting Grant (StG), PE6, ERC-2012-StG_20111012
Summary Cloud computing is being increasingly adopted by individuals, organizations, and governments. However, as the computations that are offloaded to the cloud expand to societal-critical services, the dependability requirements of cloud services become much higher, and we need to ensure that the infrastructure that supports these services is ready to meet these requirements. In particular, this proposal tackles the challenges that arise from two distinctive characteristic of the cloud infrastructure.
The first is that non-crash faults, despite being considered highly unlikely by the designers of traditional systems, become commonplace at the scale and complexity of the cloud infrastructure. We argue that the current ad-hoc methods for handling these faults are insufficient, and that the only principled approach of assuming Byzantine faults is too pessimistic. Therefore, we call for a new systematic approach to tolerating non-crash, non-adversarial faults. This requires the definition of a new fault model, and the construction of a series of building blocks and key protocol elements that enable the construction of fault-tolerant cloud services.
The second issue is that to meet their scalability requirements, cloud services spread their state across multiple data centers, and direct users to the closest one. This raises the issue that not all operations can be executed optimistically, without being aware of concurrent operations over the same data, and thus multiple levels of consistency must coexist. However, this puts the onus of reasoning about which behaviors are allowed under such a hybrid consistency model on the programmer of the service. We propose a systematic solution to this problem, which includes a novel consistency model that allows for developing highly scalable services that are fast when possible and consistent when necessary, and a labeling methodology to guide the programmer in deciding which operations can run at each consistency level.
Summary
Cloud computing is being increasingly adopted by individuals, organizations, and governments. However, as the computations that are offloaded to the cloud expand to societal-critical services, the dependability requirements of cloud services become much higher, and we need to ensure that the infrastructure that supports these services is ready to meet these requirements. In particular, this proposal tackles the challenges that arise from two distinctive characteristic of the cloud infrastructure.
The first is that non-crash faults, despite being considered highly unlikely by the designers of traditional systems, become commonplace at the scale and complexity of the cloud infrastructure. We argue that the current ad-hoc methods for handling these faults are insufficient, and that the only principled approach of assuming Byzantine faults is too pessimistic. Therefore, we call for a new systematic approach to tolerating non-crash, non-adversarial faults. This requires the definition of a new fault model, and the construction of a series of building blocks and key protocol elements that enable the construction of fault-tolerant cloud services.
The second issue is that to meet their scalability requirements, cloud services spread their state across multiple data centers, and direct users to the closest one. This raises the issue that not all operations can be executed optimistically, without being aware of concurrent operations over the same data, and thus multiple levels of consistency must coexist. However, this puts the onus of reasoning about which behaviors are allowed under such a hybrid consistency model on the programmer of the service. We propose a systematic solution to this problem, which includes a novel consistency model that allows for developing highly scalable services that are fast when possible and consistent when necessary, and a labeling methodology to guide the programmer in deciding which operations can run at each consistency level.
Max ERC Funding
1 076 084 €
Duration
Start date: 2012-10-01, End date: 2018-01-31
Project acronym ELASTIC-TURBULENCE
Project Purely-elastic flow instabilities and transition to elastic turbulence in microscale flows of complex fluids
Researcher (PI) Manuel António Moreira Alves
Host Institution (HI) UNIVERSIDADE DO PORTO
Call Details Starting Grant (StG), PE8, ERC-2012-StG_20111012
Summary Flows of complex fluids, such as many biological fluids and most synthetic fluids, are common in our daily life and are very important from an industrial perspective. Because of their inherent nonlinearity, the flow of complex viscoelastic fluids often leads to counterintuitive and complex behaviour and, above critical conditions, can prompt flow instabilities even under low Reynolds number conditions which are entirely absent in the corresponding Newtonian fluid flows.
The primary goal of this project is to substantially expand the frontiers of our current knowledge regarding the mechanisms that lead to the development of such purely-elastic flow instabilities, and ultimately to understand the transition to so-called “elastic turbulence”, a turbulent-like phenomenon which can arise even under inertialess flow conditions. This is an extremely challenging problem, and to significantly advance our knowledge in such important flows these instabilities will be investigated in a combined manner encompassing experiments, theory and numerical simulations. Such a holistic approach will enable us to understand the underlying mechanisms of those instabilities and to develop accurate criteria for their prediction far in advance of what we could achieve with either approach separately. A deep understanding of the mechanisms generating elastic instabilities and subsequent transition to elastic turbulence is crucial from a fundamental point of view and for many important practical applications involving engineered complex fluids, such as the design of microfluidic mixers for efficient operation under inertialess flow conditions, or the development of highly efficient micron-sized energy management and mass transfer systems.
This research proposal will create a solid basis for the establishment of an internationally-leading research group led by the PI studying flow instabilities and elastic turbulence in complex fluid flows.
Summary
Flows of complex fluids, such as many biological fluids and most synthetic fluids, are common in our daily life and are very important from an industrial perspective. Because of their inherent nonlinearity, the flow of complex viscoelastic fluids often leads to counterintuitive and complex behaviour and, above critical conditions, can prompt flow instabilities even under low Reynolds number conditions which are entirely absent in the corresponding Newtonian fluid flows.
The primary goal of this project is to substantially expand the frontiers of our current knowledge regarding the mechanisms that lead to the development of such purely-elastic flow instabilities, and ultimately to understand the transition to so-called “elastic turbulence”, a turbulent-like phenomenon which can arise even under inertialess flow conditions. This is an extremely challenging problem, and to significantly advance our knowledge in such important flows these instabilities will be investigated in a combined manner encompassing experiments, theory and numerical simulations. Such a holistic approach will enable us to understand the underlying mechanisms of those instabilities and to develop accurate criteria for their prediction far in advance of what we could achieve with either approach separately. A deep understanding of the mechanisms generating elastic instabilities and subsequent transition to elastic turbulence is crucial from a fundamental point of view and for many important practical applications involving engineered complex fluids, such as the design of microfluidic mixers for efficient operation under inertialess flow conditions, or the development of highly efficient micron-sized energy management and mass transfer systems.
This research proposal will create a solid basis for the establishment of an internationally-leading research group led by the PI studying flow instabilities and elastic turbulence in complex fluid flows.
Max ERC Funding
994 110 €
Duration
Start date: 2012-10-01, End date: 2018-01-31
Project acronym EXOEARTHS
Project EXtra-solar planets and stellar astrophysics: towards the detection of Other Earths
Researcher (PI) Nuno Miguel Cardoso Santos
Host Institution (HI) CENTRO DE INVESTIGACAO EM ASTRONOMIA E ASTROFISICA DA UNIVERSIDADE DO PORTO
Call Details Starting Grant (StG), PE9, ERC-2009-StG
Summary The detection of more than 300 extrasolar planets orbiting other solar-like stars opened the window to a new field of astrophysics. Many projects to search for Earth-like planets are currently under way, using a huge battery of telescopes and instruments. New instrumentation is also being developed towards this goal for use in both ground- and space-based based facilities. Since planets come as an output of the star formation process, the study of the stars hosting planets is of great importance. The stellar-planet connection is strengthened by the fact that most of the exoplanets were discovered using a Doppler radial-velocity technique, where the gravitational influence of the planet on the star and not the planet itself is actually measured. This project aims at doing frontier research to explore i) in unique detail the stellar limitations of the radial-velocity technique, as well as ways of reducing them, having in mind the detection of Earth-like planets and ii) to develop and apply software packages aiming at the study of the properties of the planet-host stars, having in mind the full characterization of the newfound planets, as well as understanding planet formation processes. These goals will improve our capacity to detect, study, and characterize new very low mass extra-solar planets. EXOEarths further fits into the fact that I am currently Co-PI of the project for a new high-resolution ultra-stable spectrograph for the VLT. The results of this project are crucial to fully exploit this new instrument. They will be also of extreme importance to current state-of-the-art planet-search projects aiming at the discovery of other Earths, in particular those making use of the radial-velocity method.
Summary
The detection of more than 300 extrasolar planets orbiting other solar-like stars opened the window to a new field of astrophysics. Many projects to search for Earth-like planets are currently under way, using a huge battery of telescopes and instruments. New instrumentation is also being developed towards this goal for use in both ground- and space-based based facilities. Since planets come as an output of the star formation process, the study of the stars hosting planets is of great importance. The stellar-planet connection is strengthened by the fact that most of the exoplanets were discovered using a Doppler radial-velocity technique, where the gravitational influence of the planet on the star and not the planet itself is actually measured. This project aims at doing frontier research to explore i) in unique detail the stellar limitations of the radial-velocity technique, as well as ways of reducing them, having in mind the detection of Earth-like planets and ii) to develop and apply software packages aiming at the study of the properties of the planet-host stars, having in mind the full characterization of the newfound planets, as well as understanding planet formation processes. These goals will improve our capacity to detect, study, and characterize new very low mass extra-solar planets. EXOEarths further fits into the fact that I am currently Co-PI of the project for a new high-resolution ultra-stable spectrograph for the VLT. The results of this project are crucial to fully exploit this new instrument. They will be also of extreme importance to current state-of-the-art planet-search projects aiming at the discovery of other Earths, in particular those making use of the radial-velocity method.
Max ERC Funding
928 090 €
Duration
Start date: 2009-10-01, End date: 2014-12-31
Project acronym NanoTrigger
Project Triggerable nanomaterials to modulate cell activity
Researcher (PI) Lino Da Silva Ferreira
Host Institution (HI) CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO
Call Details Starting Grant (StG), PE8, ERC-2012-StG_20111012
Summary The advent of molecular reprogramming and the associated opportunities for personalised and therapeutic medicine requires the development of novel systems for on-demand delivery of reprogramming factors into cells in order to modulate their activity/identity. Such triggerable systems should allow precise control of the timing, duration, magnitude and spatial release of the reprogramming factors. Furthermore, the system should allow this control even in vivo, using non-invasive means. The present project aims at developing triggerable systems able to release efficiently reprogramming factors on demand. The potential of this technology will be tested in two settings: (i) in the reprogramming of somatic cells in vitro, and (ii) in the improvement of hematopoietic stem cell engraftment in vivo, at the bone marrow. The proposed research involves a team formed by engineers, chemists, biologists and is highly multidisciplinary in nature encompassing elements of engineering, chemistry, system biology, stem cell technology and nanomedicine.
Summary
The advent of molecular reprogramming and the associated opportunities for personalised and therapeutic medicine requires the development of novel systems for on-demand delivery of reprogramming factors into cells in order to modulate their activity/identity. Such triggerable systems should allow precise control of the timing, duration, magnitude and spatial release of the reprogramming factors. Furthermore, the system should allow this control even in vivo, using non-invasive means. The present project aims at developing triggerable systems able to release efficiently reprogramming factors on demand. The potential of this technology will be tested in two settings: (i) in the reprogramming of somatic cells in vitro, and (ii) in the improvement of hematopoietic stem cell engraftment in vivo, at the bone marrow. The proposed research involves a team formed by engineers, chemists, biologists and is highly multidisciplinary in nature encompassing elements of engineering, chemistry, system biology, stem cell technology and nanomedicine.
Max ERC Funding
1 699 320 €
Duration
Start date: 2012-11-01, End date: 2017-10-31
Project acronym Universal Banking
Project Universal Banking, Corporate Control and Crises
Researcher (PI) Miguel Luis Sousa De Almeida Ferreira
Host Institution (HI) FACULDADE DE ECONOMIA DA UNIVERSIDADE NOVA DE LISBOA
Call Details Starting Grant (StG), SH1, ERC-2012-StG_20111124
Summary Financial intermediaries play a vital role in providing capital to corporations. The 2007-2009 financial crisis had dramatic consequences on the organization of the financial system that led to the rise of universal banking and financial conglomerates. Financial conglomerates have been common in Europe, but the recent developments have eroded the separation of commercial and investment banking elsewhere. Financial conglomerates act as lenders but also underwrite and trade securities, have equity stakes and sit on the board of corporations, and manage mutual and pension funds that invest in corporations. These forms of corporate control by financial conglomerates are distinct in their incentives and costs and therefore can have distinct effects on non-financial corporations. We will study the effect of control by financial conglomerates on corporation’s performance, investment, financing, and corporate governance policies. A particular relevant channel through which financial conglomerates can affect firm’s policies is the credit channel. Firms establish relationships with financial conglomerates that give easier access to credit and potentially at a lower cost due to economies of scale in information collection and monitoring. There may be, however, costs to firms with a close relationship with a financial conglomerate as firms may be locked up due to an information monopoly. We will study the effects of bank-firm relationships on the loan market. In particular, we will examine the importance of these relationships for explaining differences in the cost of bank distress across firms. The hypothesis is that strong ties with banks reduce firms’ ability to substitute relationship bank loans with other sources of external finance, and therefore firms with stronger relationships could experience greater costs during financial crises. We will contribute to the understanding the consequences of shocks to the financial health of banks for nonfinancial firms.
Summary
Financial intermediaries play a vital role in providing capital to corporations. The 2007-2009 financial crisis had dramatic consequences on the organization of the financial system that led to the rise of universal banking and financial conglomerates. Financial conglomerates have been common in Europe, but the recent developments have eroded the separation of commercial and investment banking elsewhere. Financial conglomerates act as lenders but also underwrite and trade securities, have equity stakes and sit on the board of corporations, and manage mutual and pension funds that invest in corporations. These forms of corporate control by financial conglomerates are distinct in their incentives and costs and therefore can have distinct effects on non-financial corporations. We will study the effect of control by financial conglomerates on corporation’s performance, investment, financing, and corporate governance policies. A particular relevant channel through which financial conglomerates can affect firm’s policies is the credit channel. Firms establish relationships with financial conglomerates that give easier access to credit and potentially at a lower cost due to economies of scale in information collection and monitoring. There may be, however, costs to firms with a close relationship with a financial conglomerate as firms may be locked up due to an information monopoly. We will study the effects of bank-firm relationships on the loan market. In particular, we will examine the importance of these relationships for explaining differences in the cost of bank distress across firms. The hypothesis is that strong ties with banks reduce firms’ ability to substitute relationship bank loans with other sources of external finance, and therefore firms with stronger relationships could experience greater costs during financial crises. We will contribute to the understanding the consequences of shocks to the financial health of banks for nonfinancial firms.
Max ERC Funding
1 174 000 €
Duration
Start date: 2013-03-01, End date: 2018-02-28
