Project acronym 3-TOP
Project Exploring the physics of 3-dimensional topological insulators
Researcher (PI) Laurens Wigbolt Molenkamp
Host Institution (HI) JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
Call Details Advanced Grant (AdG), PE3, ERC-2010-AdG_20100224
Summary Topological insulators constitute a novel class of materials where the topological details of the bulk band structure induce a robust surface state on the edges of the material. While transport data for 2-dimensional topological insulators have recently become available, experiments on their 3-dimensional counterparts are mainly limited to photoelectron spectroscopy. At the same time, a plethora of interesting novel physical phenomena have been predicted to occur in such systems.
In this proposal, we sketch an approach to tackle the transport and magnetic properties of the surface states in these materials. This starts with high quality layer growth, using molecular beam epitaxy, of bulk layers of HgTe, Bi2Se3 and Bi2Te3, which are the prime candidates to show the novel physics expected in this field. The existence of the relevant surface states will be assessed spectroscopically, but from there on research will focus on fabricating and characterizing nanostructures designed to elucidate the transport and magnetic properties of the topological surfaces using electrical, optical and scanning probe techniques. Apart from a general characterization of the Dirac band structure of the surface states, research will focus on the predicted magnetic monopole-like response of the system to an electrical test charge. In addition, much effort will be devoted to contacting the surface state with superconducting and magnetic top layers, with the final aim of demonstrating Majorana fermion behavior. As a final benefit, growth of thin high quality thin Bi2Se3 or Bi2Te3 layers could allow for a demonstration of the (2-dimensional) quantum spin Hall effect at room temperature - offering a road map to dissipation-less transport for the semiconductor industry.
Summary
Topological insulators constitute a novel class of materials where the topological details of the bulk band structure induce a robust surface state on the edges of the material. While transport data for 2-dimensional topological insulators have recently become available, experiments on their 3-dimensional counterparts are mainly limited to photoelectron spectroscopy. At the same time, a plethora of interesting novel physical phenomena have been predicted to occur in such systems.
In this proposal, we sketch an approach to tackle the transport and magnetic properties of the surface states in these materials. This starts with high quality layer growth, using molecular beam epitaxy, of bulk layers of HgTe, Bi2Se3 and Bi2Te3, which are the prime candidates to show the novel physics expected in this field. The existence of the relevant surface states will be assessed spectroscopically, but from there on research will focus on fabricating and characterizing nanostructures designed to elucidate the transport and magnetic properties of the topological surfaces using electrical, optical and scanning probe techniques. Apart from a general characterization of the Dirac band structure of the surface states, research will focus on the predicted magnetic monopole-like response of the system to an electrical test charge. In addition, much effort will be devoted to contacting the surface state with superconducting and magnetic top layers, with the final aim of demonstrating Majorana fermion behavior. As a final benefit, growth of thin high quality thin Bi2Se3 or Bi2Te3 layers could allow for a demonstration of the (2-dimensional) quantum spin Hall effect at room temperature - offering a road map to dissipation-less transport for the semiconductor industry.
Max ERC Funding
2 419 590 €
Duration
Start date: 2011-04-01, End date: 2016-03-31
Project acronym 3FLEX
Project Three-Component Fermi Gas Lattice Experiment
Researcher (PI) Selim Jochim
Host Institution (HI) RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Call Details Starting Grant (StG), PE2, ERC-2011-StG_20101014
Summary Understanding the many-body physics of strongly correlated systems has always been a major challenge for theoretical and experimental physics. The recent advances in the field of ultracold quantum gases have opened a completely new way to study such strongly correlated systems. It is now feasible to use ultracold gases as quantum simulators for such diverse systems such as the Hubbard model or the BCS-BEC crossover. The objective of this project is to study a three-component Fermi gas in an optical lattice, a system with rich many-body physics. With our experiments we aim to contribute to the understanding of exotic phases which are discussed in the context of QCD and condensed matter physics.
Summary
Understanding the many-body physics of strongly correlated systems has always been a major challenge for theoretical and experimental physics. The recent advances in the field of ultracold quantum gases have opened a completely new way to study such strongly correlated systems. It is now feasible to use ultracold gases as quantum simulators for such diverse systems such as the Hubbard model or the BCS-BEC crossover. The objective of this project is to study a three-component Fermi gas in an optical lattice, a system with rich many-body physics. With our experiments we aim to contribute to the understanding of exotic phases which are discussed in the context of QCD and condensed matter physics.
Max ERC Funding
1 469 040 €
Duration
Start date: 2011-08-01, End date: 2016-07-31
Project acronym ACCRETE
Project Accretion and Early Differentiation of the Earth and Terrestrial Planets
Researcher (PI) David Crowhurst Rubie
Host Institution (HI) UNIVERSITAET BAYREUTH
Call Details Advanced Grant (AdG), PE10, ERC-2011-ADG_20110209
Summary Formation of the Earth and the other terrestrial planets of our Solar System (Mercury, Venus and Mars) commenced 4.568 billion years ago and occurred on a time scale of about 100 million years. These planets grew by the process of accretion, which involved numerous collisions with smaller (Moon- to Mars-size) bodies. Impacts with such bodies released sufficient energy to cause large-scale melting and the formation of deep “magma oceans”. Such magma oceans enabled liquid metal to separate from liquid silicate, sink and accumulate to form the metallic cores of the planets. Thus core formation in terrestrial planets was a multistage process, intimately related to the major impacts during accretion, that determined the chemistry of planetary mantles. However, until now, accretion, as modelled by astrophysicists, and core formation, as modelled by geochemists, have been treated as completely independent processes. The fundamental and crucial aim of this ambitious interdisciplinary proposal is to integrate astrophysical models of planetary accretion with geochemical models of planetary differentiation together with cosmochemical constraints obtained from meteorites. The research will involve integrating new models of planetary accretion with core formation models based on the partitioning of a large number of elements between liquid metal and liquid silicate that we will determine experimentally at pressures up to about 100 gigapascals (equivalent to 2400 km deep in the Earth). By comparing our results with the known physical and chemical characteristics of the terrestrial planets, we will obtain a comprehensive understanding of how these planets formed, grew and evolved, both physically and chemically, with time. The integration of chemistry and planetary differentiation with accretion models is a new ground-breaking concept that will lead, through synergies and feedback, to major new advances in the Earth and planetary sciences.
Summary
Formation of the Earth and the other terrestrial planets of our Solar System (Mercury, Venus and Mars) commenced 4.568 billion years ago and occurred on a time scale of about 100 million years. These planets grew by the process of accretion, which involved numerous collisions with smaller (Moon- to Mars-size) bodies. Impacts with such bodies released sufficient energy to cause large-scale melting and the formation of deep “magma oceans”. Such magma oceans enabled liquid metal to separate from liquid silicate, sink and accumulate to form the metallic cores of the planets. Thus core formation in terrestrial planets was a multistage process, intimately related to the major impacts during accretion, that determined the chemistry of planetary mantles. However, until now, accretion, as modelled by astrophysicists, and core formation, as modelled by geochemists, have been treated as completely independent processes. The fundamental and crucial aim of this ambitious interdisciplinary proposal is to integrate astrophysical models of planetary accretion with geochemical models of planetary differentiation together with cosmochemical constraints obtained from meteorites. The research will involve integrating new models of planetary accretion with core formation models based on the partitioning of a large number of elements between liquid metal and liquid silicate that we will determine experimentally at pressures up to about 100 gigapascals (equivalent to 2400 km deep in the Earth). By comparing our results with the known physical and chemical characteristics of the terrestrial planets, we will obtain a comprehensive understanding of how these planets formed, grew and evolved, both physically and chemically, with time. The integration of chemistry and planetary differentiation with accretion models is a new ground-breaking concept that will lead, through synergies and feedback, to major new advances in the Earth and planetary sciences.
Max ERC Funding
1 826 200 €
Duration
Start date: 2012-05-01, End date: 2018-04-30
Project acronym AMPCAT
Project Self-Amplifying Stereodynamic Catalysts in Enantioselective Catalysis
Researcher (PI) Oliver Trapp
Host Institution (HI) RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Call Details Starting Grant (StG), PE5, ERC-2010-StG_20091028
Summary Think about an enantioselective catalyst, which can switch its enantioselectivity and which can be imprinted and provides self-amplification by its own chiral reaction product. Think about a catalyst, which can be fine-tuned for efficient stereoselective synthesis of drugs and other materials, e.g. polymers.
Highly promising reactions such as enantioselective autocatalysis (Soai reaction) and chiral catalysts undergoing dynamic interconversions, e.g. BIPHEP ligands, are still not understood. Their application is very limited to a few compounds, which opens the field for novel investigations.
I propose the development of a smart or switchable chiral ligand undergoing dynamic interconversions. These catalysts will be tuned by their reaction product, and this leads to self-amplification of one of the stereoisomers. I propose a novel fundamental mechanism which has the potential to overcome the limitations of the Soai reaction, exploiting the full potential of enantioselective catalysis.
As representatives of enantioselective self-amplifying stereodynamic catalysts a novel class of diazirine based ligands will be developed, their interconversion barrier is tuneable between 80 and 130 kJ/mol. Specifically, following areas will be explored:
1. Investigation of the kinetics and thermodynamics of the Soai reaction as a model reaction by analysis of large sets of kinetic data.
2. Ligands with diaziridine moieties with flexible structure will be designed and investigated, to control the enantioselectivity.
3. Design of a ligand receptor group for product interaction to switch the chirality. Study of self-amplification in enantioselective processes.
4. Enantioselective hydrogenations, Diels-Alder reactions, epoxidations and reactions generating multiple stereocenters will be targeted.
Summary
Think about an enantioselective catalyst, which can switch its enantioselectivity and which can be imprinted and provides self-amplification by its own chiral reaction product. Think about a catalyst, which can be fine-tuned for efficient stereoselective synthesis of drugs and other materials, e.g. polymers.
Highly promising reactions such as enantioselective autocatalysis (Soai reaction) and chiral catalysts undergoing dynamic interconversions, e.g. BIPHEP ligands, are still not understood. Their application is very limited to a few compounds, which opens the field for novel investigations.
I propose the development of a smart or switchable chiral ligand undergoing dynamic interconversions. These catalysts will be tuned by their reaction product, and this leads to self-amplification of one of the stereoisomers. I propose a novel fundamental mechanism which has the potential to overcome the limitations of the Soai reaction, exploiting the full potential of enantioselective catalysis.
As representatives of enantioselective self-amplifying stereodynamic catalysts a novel class of diazirine based ligands will be developed, their interconversion barrier is tuneable between 80 and 130 kJ/mol. Specifically, following areas will be explored:
1. Investigation of the kinetics and thermodynamics of the Soai reaction as a model reaction by analysis of large sets of kinetic data.
2. Ligands with diaziridine moieties with flexible structure will be designed and investigated, to control the enantioselectivity.
3. Design of a ligand receptor group for product interaction to switch the chirality. Study of self-amplification in enantioselective processes.
4. Enantioselective hydrogenations, Diels-Alder reactions, epoxidations and reactions generating multiple stereocenters will be targeted.
Max ERC Funding
1 452 000 €
Duration
Start date: 2010-12-01, End date: 2016-05-31
Project acronym ANAMULTISCALE
Project Analysis of Multiscale Systems Driven by Functionals
Researcher (PI) Alexander Mielke
Host Institution (HI) FORSCHUNGSVERBUND BERLIN EV
Call Details Advanced Grant (AdG), PE1, ERC-2010-AdG_20100224
Summary Many complex phenomena in the sciences are described by nonlinear partial differential equations, the solutions of which exhibit oscillations and concentration effects on multiple temporal or spatial scales. Our aim is to use methods from applied analysis to contribute to the understanding of the interplay of effects on different scales. The central question is to determine those quantities on the microscale which are needed to for the correct description of the macroscopic evolution.
We aim to develop a mathematical framework for analyzing and modeling coupled systems with multiple scales. This will include Hamiltonian dynamics as well as different types of dissipation like gradient flows or rate-independent dynamics. The choice of models will be guided by specific applications in material modeling (e.g., thermoplasticity, pattern formation, porous media) and optoelectronics (pulse interaction, Maxwell-Bloch systems, semiconductors, quantum mechanics). The research will address mathematically fundamental issues like existence and stability of solutions but will mainly be devoted to the modeling of multiscale phenomena in evolution systems. We will focus on systems with geometric structures, where the dynamics is driven by functionals. Thus, we can go much beyond the classical theory of homogenization and singular perturbations. The novel features of our approach are
- the combination of different dynamical effects in one framework,
- the use of geometric and metric structures for coupled partial differential equations,
- the exploitation of Gamma-convergence for evolution systems driven by functionals.
Summary
Many complex phenomena in the sciences are described by nonlinear partial differential equations, the solutions of which exhibit oscillations and concentration effects on multiple temporal or spatial scales. Our aim is to use methods from applied analysis to contribute to the understanding of the interplay of effects on different scales. The central question is to determine those quantities on the microscale which are needed to for the correct description of the macroscopic evolution.
We aim to develop a mathematical framework for analyzing and modeling coupled systems with multiple scales. This will include Hamiltonian dynamics as well as different types of dissipation like gradient flows or rate-independent dynamics. The choice of models will be guided by specific applications in material modeling (e.g., thermoplasticity, pattern formation, porous media) and optoelectronics (pulse interaction, Maxwell-Bloch systems, semiconductors, quantum mechanics). The research will address mathematically fundamental issues like existence and stability of solutions but will mainly be devoted to the modeling of multiscale phenomena in evolution systems. We will focus on systems with geometric structures, where the dynamics is driven by functionals. Thus, we can go much beyond the classical theory of homogenization and singular perturbations. The novel features of our approach are
- the combination of different dynamical effects in one framework,
- the use of geometric and metric structures for coupled partial differential equations,
- the exploitation of Gamma-convergence for evolution systems driven by functionals.
Max ERC Funding
1 390 000 €
Duration
Start date: 2011-04-01, End date: 2017-03-31
Project acronym ANOPTSETCON
Project Analysis of optimal sets and optimal constants: old questions and new results
Researcher (PI) Aldo Pratelli
Host Institution (HI) FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG
Call Details Starting Grant (StG), PE1, ERC-2010-StG_20091028
Summary The analysis of geometric and functional inequalities naturally leads to consider the extremal cases, thus
looking for optimal sets, or optimal functions, or optimal constants. The most classical examples are the (different versions of the) isoperimetric inequality and the Sobolev-like inequalities. Much is known about equality cases and best constants, but there are still many questions which seem quite natural but yet have no answer. For instance, it is not known, even in the 2-dimensional space, the answer of a question by Brezis: which set,
among those with a given volume, has the biggest Sobolev-Poincaré constant for p=1? This is a very natural problem, and it appears reasonable that the optimal set should be the ball, but this has never been proved. The interest in problems like this relies not only in the extreme simplicity of the questions and in their classical flavour, but also in the new ideas and techniques which are needed to provide the answers.
The main techniques that we aim to use are fine arguments of symmetrization, geometric constructions and tools from mass transportation (which is well known to be deeply connected with functional inequalities). These are the basic tools that we already used to reach, in last years, many results in a specific direction, namely the search of sharp quantitative inequalities. Our first result, together with Fusco and Maggi, showed what follows. Everybody knows that the set which minimizes the perimeter with given volume is the ball.
But is it true that a set which almost minimizes the perimeter must be close to a ball? The question had been posed in the 1920's and many partial result appeared in the years. In our paper (Ann. of Math., 2007) we proved the sharp result. Many other results of this kind were obtained in last two years.
Summary
The analysis of geometric and functional inequalities naturally leads to consider the extremal cases, thus
looking for optimal sets, or optimal functions, or optimal constants. The most classical examples are the (different versions of the) isoperimetric inequality and the Sobolev-like inequalities. Much is known about equality cases and best constants, but there are still many questions which seem quite natural but yet have no answer. For instance, it is not known, even in the 2-dimensional space, the answer of a question by Brezis: which set,
among those with a given volume, has the biggest Sobolev-Poincaré constant for p=1? This is a very natural problem, and it appears reasonable that the optimal set should be the ball, but this has never been proved. The interest in problems like this relies not only in the extreme simplicity of the questions and in their classical flavour, but also in the new ideas and techniques which are needed to provide the answers.
The main techniques that we aim to use are fine arguments of symmetrization, geometric constructions and tools from mass transportation (which is well known to be deeply connected with functional inequalities). These are the basic tools that we already used to reach, in last years, many results in a specific direction, namely the search of sharp quantitative inequalities. Our first result, together with Fusco and Maggi, showed what follows. Everybody knows that the set which minimizes the perimeter with given volume is the ball.
But is it true that a set which almost minimizes the perimeter must be close to a ball? The question had been posed in the 1920's and many partial result appeared in the years. In our paper (Ann. of Math., 2007) we proved the sharp result. Many other results of this kind were obtained in last two years.
Max ERC Funding
540 000 €
Duration
Start date: 2010-08-01, End date: 2015-07-31
Project acronym ANTHOS
Project Analytic Number Theory: Higher Order Structures
Researcher (PI) Valentin Blomer
Host Institution (HI) GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS
Call Details Starting Grant (StG), PE1, ERC-2010-StG_20091028
Summary This is a proposal for research at the interface of analytic number theory, automorphic forms and algebraic geometry. Motivated by fundamental conjectures in number theory, classical problems will be investigated in higher order situations: general number fields, automorphic forms on higher rank groups, the arithmetic of algebraic varieties of higher degree. In particular, I want to focus on
- computation of moments of L-function of degree 3 and higher with applications to subconvexity and/or non-vanishing, as well as subconvexity for multiple L-functions;
- bounds for sup-norms of cusp forms on various spaces and equidistribution of Hecke correspondences;
- automorphic forms on higher rank groups and general number fields, in particular new bounds towards the Ramanujan conjecture;
- a proof of Manin's conjecture for a certain class of singular algebraic varieties.
The underlying methods are closely related; for example, rational points on algebraic varieties
will be counted by a multiple L-series technique.
Summary
This is a proposal for research at the interface of analytic number theory, automorphic forms and algebraic geometry. Motivated by fundamental conjectures in number theory, classical problems will be investigated in higher order situations: general number fields, automorphic forms on higher rank groups, the arithmetic of algebraic varieties of higher degree. In particular, I want to focus on
- computation of moments of L-function of degree 3 and higher with applications to subconvexity and/or non-vanishing, as well as subconvexity for multiple L-functions;
- bounds for sup-norms of cusp forms on various spaces and equidistribution of Hecke correspondences;
- automorphic forms on higher rank groups and general number fields, in particular new bounds towards the Ramanujan conjecture;
- a proof of Manin's conjecture for a certain class of singular algebraic varieties.
The underlying methods are closely related; for example, rational points on algebraic varieties
will be counted by a multiple L-series technique.
Max ERC Funding
1 004 000 €
Duration
Start date: 2010-10-01, End date: 2015-09-30
Project acronym ANTIBACTERIALS
Project Natural products and their cellular targets: A multidisciplinary strategy for antibacterial drug discovery
Researcher (PI) Stephan Axel Sieber
Host Institution (HI) TECHNISCHE UNIVERSITAET MUENCHEN
Call Details Starting Grant (StG), PE5, ERC-2010-StG_20091028
Summary After decades of successful treatment of bacterial infections with antibiotics, formerly treatable bacteria have developed drug resistance and consequently pose a major threat to public health. To address the urgent need for effective antibacterial drugs we will develop a streamlined chemical-biology platform that facilitates the consolidated identification and structural elucidation of natural products together with their dedicated cellular targets. This innovative concept overcomes several limitations of classical drug discovery processes by a chemical strategy that focuses on a directed isolation, enrichment and identification procedure for certain privileged natural product subclasses. This proposal consists of four specific aims: 1) synthesizing enzyme active site mimetics that capture protein reactive natural products out of complex natural sources, 2) designing natural product based probes to identify their cellular targets by a method called activity based protein profiling , 3) developing a traceless photocrosslinking strategy for the target identification of selected non-reactive natural products, and 4) application of all probes to identify novel enzyme activities linked to viability, resistance and pathogenesis. Moreover, the compounds will be used to monitor the infection process during invasion into eukaryotic cells and will reveal host specific targets that promote and support bacterial pathogenesis. Inhibition of these targets is a novel and so far neglected approach in the treatment of infectious diseases. We anticipate that these studies will provide a powerful pharmacological platform for the development of potent natural product derived antibacterial agents directed toward novel therapeutic targets.
Summary
After decades of successful treatment of bacterial infections with antibiotics, formerly treatable bacteria have developed drug resistance and consequently pose a major threat to public health. To address the urgent need for effective antibacterial drugs we will develop a streamlined chemical-biology platform that facilitates the consolidated identification and structural elucidation of natural products together with their dedicated cellular targets. This innovative concept overcomes several limitations of classical drug discovery processes by a chemical strategy that focuses on a directed isolation, enrichment and identification procedure for certain privileged natural product subclasses. This proposal consists of four specific aims: 1) synthesizing enzyme active site mimetics that capture protein reactive natural products out of complex natural sources, 2) designing natural product based probes to identify their cellular targets by a method called activity based protein profiling , 3) developing a traceless photocrosslinking strategy for the target identification of selected non-reactive natural products, and 4) application of all probes to identify novel enzyme activities linked to viability, resistance and pathogenesis. Moreover, the compounds will be used to monitor the infection process during invasion into eukaryotic cells and will reveal host specific targets that promote and support bacterial pathogenesis. Inhibition of these targets is a novel and so far neglected approach in the treatment of infectious diseases. We anticipate that these studies will provide a powerful pharmacological platform for the development of potent natural product derived antibacterial agents directed toward novel therapeutic targets.
Max ERC Funding
1 500 000 €
Duration
Start date: 2010-11-01, End date: 2015-10-31
Project acronym ASMIDIAS
Project Asymmetric microenvironments by directed assembly: Control of geometry, topography, surface biochemistry and mechanical properties via a microscale modular design principle
Researcher (PI) Holger Dr. Schönherr
Host Institution (HI) UNIVERSITAET SIEGEN
Call Details Starting Grant (StG), PE5, ERC-2011-StG_20101014
Summary The interaction of cells with the extracellular matrix or neighboring cells plays a crucial role in many cellular functions, such as motility, differentiation and controlled cell death. Expanding on pioneering studies on defined 2-D model systems, the role of the currently known determinants (geometry, topography, biochemical functionality and mechanical properties) is currently addressed in more relevant 3-D matrices. However, there is a clear lack in currently available approaches to fabricate well defined microenvironments, which are asymmetric or in which these factors can be varied independently. The central objective of ASMIDIAS is the development of a novel route to asymmetric microenvironments for cell-matrix interaction studies. Inspired by molecular self-assembly on the one hand and guided macroscale assembly on the other hand, directed assembly of highly defined microfabricated building blocks will be exploited to this end. In this modular design approach different building blocks position themselves during assembly on pre-structured surfaces to afford enclosed volumes that are restricted by the walls of the blocks. The project relies on two central elements. For the guided assembly, the balance of attractive and repulsive interactions between the building blocks (and its dependence on the object dimensions) and the structured surface shall be controlled by appropriate surface chemistry and suitable guiding structures. To afford the required functionality, new approaches to (i) topographically structure, (ii) biochemically functionalize and pattern selected sides of the microscale building blocks and (iii) to control their surface elastic properties via surface-attached polymers and hydrogels, will be developed.The resulting unique asymmetric environments will facilitate novel insight into cell-matrix interactions, which possess considerable relevance in the areas of tissue engineering, cell (de)differentiation, bacteria-surface interactions and beyond.
Summary
The interaction of cells with the extracellular matrix or neighboring cells plays a crucial role in many cellular functions, such as motility, differentiation and controlled cell death. Expanding on pioneering studies on defined 2-D model systems, the role of the currently known determinants (geometry, topography, biochemical functionality and mechanical properties) is currently addressed in more relevant 3-D matrices. However, there is a clear lack in currently available approaches to fabricate well defined microenvironments, which are asymmetric or in which these factors can be varied independently. The central objective of ASMIDIAS is the development of a novel route to asymmetric microenvironments for cell-matrix interaction studies. Inspired by molecular self-assembly on the one hand and guided macroscale assembly on the other hand, directed assembly of highly defined microfabricated building blocks will be exploited to this end. In this modular design approach different building blocks position themselves during assembly on pre-structured surfaces to afford enclosed volumes that are restricted by the walls of the blocks. The project relies on two central elements. For the guided assembly, the balance of attractive and repulsive interactions between the building blocks (and its dependence on the object dimensions) and the structured surface shall be controlled by appropriate surface chemistry and suitable guiding structures. To afford the required functionality, new approaches to (i) topographically structure, (ii) biochemically functionalize and pattern selected sides of the microscale building blocks and (iii) to control their surface elastic properties via surface-attached polymers and hydrogels, will be developed.The resulting unique asymmetric environments will facilitate novel insight into cell-matrix interactions, which possess considerable relevance in the areas of tissue engineering, cell (de)differentiation, bacteria-surface interactions and beyond.
Max ERC Funding
1 484 100 €
Duration
Start date: 2011-11-01, End date: 2016-10-31
Project acronym ASYMMETRY
Project Measurement of CP violation in the B_s system at LHCb
Researcher (PI) Stephanie Hansmann-Menzemer
Host Institution (HI) RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Call Details Starting Grant (StG), PE2, ERC-2010-StG_20091028
Summary The Large Hadron collider (LHC) at CERN will be a milestone for the understanding of fundamental interactions and for the future of high energy
physics. Four large experiments at the LHC are complementarily addressing the question of the origin of our Universe by searching for so-called New Physics.
The world of particles and their interactions is nowadays described by the Standard Model. Up to now there is no single measurement from laboratory experiments which contradicts this theory. However, there are still many open questions, thus physicists are convinced that there is a more fundamental theory, which incorporates New Physics.
It is expected that at the LHC either New Physics beyond the Standard Model will be discovered or excluded up to very high energies, which would revolutionize the understanding of particle physics and require completely new experimental and theoretical concepts.
The LHCb (Large Hadron Collider beauty) experiment is dedicated to precision measurements of B hadrons (B hadrons are all particles containing a beauty quark).
The analysis proposed here is the measurement of asymmetries between B_s particles and anti-B_s particles at the LHCb experiment. Any New Physics model will change the rate of observable processes via additional quantum corrections. Particle antiparticle asymmetries are extremely sensitive to these corrections thus a very powerful tool for indirect searches for New Physics contributions. In the past, most of the ground-breaking findings in particle physics, such as the existence of the
charm quark and the existence of a third quark family, have first been observed in indirect searches.
First - still statistically limited - measurements of the asymmetry in the B_s system indicate a 2 sigma deviation from the Standard Model prediction. A precision measurement of this asymmetry is potentially the first observation for New Physics beyond the Standard Model at the LHC. If no hint for New Physics will be found, this measurement will severely restrict the range of potential New Physics models.
Summary
The Large Hadron collider (LHC) at CERN will be a milestone for the understanding of fundamental interactions and for the future of high energy
physics. Four large experiments at the LHC are complementarily addressing the question of the origin of our Universe by searching for so-called New Physics.
The world of particles and their interactions is nowadays described by the Standard Model. Up to now there is no single measurement from laboratory experiments which contradicts this theory. However, there are still many open questions, thus physicists are convinced that there is a more fundamental theory, which incorporates New Physics.
It is expected that at the LHC either New Physics beyond the Standard Model will be discovered or excluded up to very high energies, which would revolutionize the understanding of particle physics and require completely new experimental and theoretical concepts.
The LHCb (Large Hadron Collider beauty) experiment is dedicated to precision measurements of B hadrons (B hadrons are all particles containing a beauty quark).
The analysis proposed here is the measurement of asymmetries between B_s particles and anti-B_s particles at the LHCb experiment. Any New Physics model will change the rate of observable processes via additional quantum corrections. Particle antiparticle asymmetries are extremely sensitive to these corrections thus a very powerful tool for indirect searches for New Physics contributions. In the past, most of the ground-breaking findings in particle physics, such as the existence of the
charm quark and the existence of a third quark family, have first been observed in indirect searches.
First - still statistically limited - measurements of the asymmetry in the B_s system indicate a 2 sigma deviation from the Standard Model prediction. A precision measurement of this asymmetry is potentially the first observation for New Physics beyond the Standard Model at the LHC. If no hint for New Physics will be found, this measurement will severely restrict the range of potential New Physics models.
Max ERC Funding
1 059 240 €
Duration
Start date: 2011-01-01, End date: 2015-12-31
