Project acronym ACHILLES-HEEL
Project Crop resistance improvement by mining natural and induced variation in host accessibility factors
Researcher (PI) Sebastian Schornack
Host Institution (HI) THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Call Details Starting Grant (StG), LS9, ERC-2014-STG
Summary Increasing crop yield to feed the world is a grand challenge of the 21st century but it is hampered by diseases caused by filamentous plant pathogens. The arms race between pathogen and plant demands constant adjustment of crop germplasm to tackle emerging pathogen races with new virulence features. To date, most crop disease resistance has relied on specific resistance genes that are effective only against a subset of races. We cannot solely rely on classical resistance genes to keep ahead of the pathogens. There is an urgent need to develop approaches based on knowledge of the pathogen’s Achilles heel: core plant processes that are required for pathogen colonization.
Our hypothesis is that disease resistance based on manipulation of host accessibility processes has a higher probability for durability, and is best identified using a broad host-range pathogen. I will employ the filamentous pathogen Phytophthora palmivora to mine plant alleles and unravel host processes providing microbial access in roots and leaves of monocot and dicot plants.
In Aim 1 I will utilize plant symbiosis mutants and allelic variation to elucidate general mechanisms of colonization by filamentous microbes. Importantly, allelic variation will be studied in economically relevant barley and wheat to allow immediate translation into breeding programs.
In Aim 2 I will perform a comparative study of microbial colonization in monocot and dicot roots and leaves. Transcriptional profiling of pathogen and plant will highlight common and contrasting principles and illustrate the impact of differential plant anatomies.
We will challenge our findings by testing beneficial fungi to assess commonalities and differences between mutualist and pathogen colonization. We will use genetics, cell biology and genomics to find suitable resistance alleles highly relevant to crop production and global food security. At the completion of the project, I expect to have a set of genes for resistance breeding.
Summary
Increasing crop yield to feed the world is a grand challenge of the 21st century but it is hampered by diseases caused by filamentous plant pathogens. The arms race between pathogen and plant demands constant adjustment of crop germplasm to tackle emerging pathogen races with new virulence features. To date, most crop disease resistance has relied on specific resistance genes that are effective only against a subset of races. We cannot solely rely on classical resistance genes to keep ahead of the pathogens. There is an urgent need to develop approaches based on knowledge of the pathogen’s Achilles heel: core plant processes that are required for pathogen colonization.
Our hypothesis is that disease resistance based on manipulation of host accessibility processes has a higher probability for durability, and is best identified using a broad host-range pathogen. I will employ the filamentous pathogen Phytophthora palmivora to mine plant alleles and unravel host processes providing microbial access in roots and leaves of monocot and dicot plants.
In Aim 1 I will utilize plant symbiosis mutants and allelic variation to elucidate general mechanisms of colonization by filamentous microbes. Importantly, allelic variation will be studied in economically relevant barley and wheat to allow immediate translation into breeding programs.
In Aim 2 I will perform a comparative study of microbial colonization in monocot and dicot roots and leaves. Transcriptional profiling of pathogen and plant will highlight common and contrasting principles and illustrate the impact of differential plant anatomies.
We will challenge our findings by testing beneficial fungi to assess commonalities and differences between mutualist and pathogen colonization. We will use genetics, cell biology and genomics to find suitable resistance alleles highly relevant to crop production and global food security. At the completion of the project, I expect to have a set of genes for resistance breeding.
Max ERC Funding
1 991 054 €
Duration
Start date: 2015-09-01, End date: 2021-08-31
Project acronym BCOOL
Project Barocaloric materials for energy-efficient solid-state cooling
Researcher (PI) Javier Eduardo Moya Raposo
Host Institution (HI) THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Call Details Starting Grant (StG), PE8, ERC-2015-STG
Summary Cooling is essential for food and drinks, medicine, electronics and thermal comfort. Thermal changes due to pressure-driven phase transitions in fluids have long been used in vapour compression systems to achieve continuous refrigeration and air conditioning, but their energy efficiency is relatively low, and the working fluids that are employed harm the environment when released to the atmosphere. More recently, the discovery of large thermal changes due to pressure-driven phase transitions in magnetic solids has led to suggestions for environmentally friendly solid-state cooling applications. However, for this new cooling technology to succeed, it is still necessary to find suitable barocaloric (BC) materials that satisfy the demanding requirements set by applications, namely very large thermal changes in inexpensive materials that occur near room temperature in response to small applied pressures.
I aim to develop new BC materials by exploiting phase transitions in non-magnetic solids whose structural and thermal properties are strongly coupled, namely ferroelectric salts, molecular crystals and hybrid materials. These materials are normally made from cheap abundant elements, and display very large latent heats and volume changes at structural phase transitions, which make them ideal candidates to exhibit extremely large BC effects that outperform those observed in state-of-the-art BC magnetic materials, and that match applications.
My unique approach combines: i) materials science to identify materials with outstanding BC performance, ii) advanced experimental techniques to explore and exploit these novel materials, iii) materials engineering to create new composite materials with enhanced BC properties, and iv) fabrication of BC devices, using insight gained from modelling of materials and device parameters. If successful, my ambitious strategy will culminate in revolutionary solid-state cooling devices that are environmentally friendly and energy efficient.
Summary
Cooling is essential for food and drinks, medicine, electronics and thermal comfort. Thermal changes due to pressure-driven phase transitions in fluids have long been used in vapour compression systems to achieve continuous refrigeration and air conditioning, but their energy efficiency is relatively low, and the working fluids that are employed harm the environment when released to the atmosphere. More recently, the discovery of large thermal changes due to pressure-driven phase transitions in magnetic solids has led to suggestions for environmentally friendly solid-state cooling applications. However, for this new cooling technology to succeed, it is still necessary to find suitable barocaloric (BC) materials that satisfy the demanding requirements set by applications, namely very large thermal changes in inexpensive materials that occur near room temperature in response to small applied pressures.
I aim to develop new BC materials by exploiting phase transitions in non-magnetic solids whose structural and thermal properties are strongly coupled, namely ferroelectric salts, molecular crystals and hybrid materials. These materials are normally made from cheap abundant elements, and display very large latent heats and volume changes at structural phase transitions, which make them ideal candidates to exhibit extremely large BC effects that outperform those observed in state-of-the-art BC magnetic materials, and that match applications.
My unique approach combines: i) materials science to identify materials with outstanding BC performance, ii) advanced experimental techniques to explore and exploit these novel materials, iii) materials engineering to create new composite materials with enhanced BC properties, and iv) fabrication of BC devices, using insight gained from modelling of materials and device parameters. If successful, my ambitious strategy will culminate in revolutionary solid-state cooling devices that are environmentally friendly and energy efficient.
Max ERC Funding
1 467 521 €
Duration
Start date: 2016-04-01, End date: 2021-03-31
Project acronym BIAF
Project Bird Inspired Autonomous Flight
Researcher (PI) Shane Paul Windsor
Host Institution (HI) UNIVERSITY OF BRISTOL
Call Details Starting Grant (StG), PE8, ERC-2015-STG
Summary The agile and efficient flight of birds shows what flight performance is physically possible, and in theory could be achieved by unmanned air vehicles (UAVs) of the same size. The overall aim of this project is to enhance the performance of small scale UAVs by developing novel technologies inspired by understanding how birds are adapted to interact with airflows. Small UAVs have the potential to dramatically change current practices in many areas such as, search and rescue, surveillance, and environmental monitoring. Currently the utility of these systems is limited by their operational endurance and their inability to operate in strong turbulent winds, especially those that often occur in urban environments. Birds are adapted to be able to fly in these conditions and actually use them to their advantage to minimise their energy output.
This project is composed of three tracks which contain elements of technology development, as well as scientific investigation looking at bird flight behaviour and aerodynamics. The first track looks at developing path planning algorithms for UAVs in urban environments based on how birds fly in these areas, by using GPS tracking and computational fluid dynamics alongside trajectory optimization. The second track aims to develop artificial wings with improved gust tolerance inspired by the features of feathered wings. Here, high speed video measurements of birds flying through gusts will be used alongside wind tunnel testing of artificial wings to discover what features of a bird’s wing help to alleviate gusts. The third track develops novel force and flow sensor arrays for autonomous flight control based on the sensor arrays found in flying animals. These arrays will be used to make UAVs with increased agility and robustness. This unique bird inspired approach uses biology to show what is possible, and engineering to find the features that enable this performance and develop them into functional technologies.
Summary
The agile and efficient flight of birds shows what flight performance is physically possible, and in theory could be achieved by unmanned air vehicles (UAVs) of the same size. The overall aim of this project is to enhance the performance of small scale UAVs by developing novel technologies inspired by understanding how birds are adapted to interact with airflows. Small UAVs have the potential to dramatically change current practices in many areas such as, search and rescue, surveillance, and environmental monitoring. Currently the utility of these systems is limited by their operational endurance and their inability to operate in strong turbulent winds, especially those that often occur in urban environments. Birds are adapted to be able to fly in these conditions and actually use them to their advantage to minimise their energy output.
This project is composed of three tracks which contain elements of technology development, as well as scientific investigation looking at bird flight behaviour and aerodynamics. The first track looks at developing path planning algorithms for UAVs in urban environments based on how birds fly in these areas, by using GPS tracking and computational fluid dynamics alongside trajectory optimization. The second track aims to develop artificial wings with improved gust tolerance inspired by the features of feathered wings. Here, high speed video measurements of birds flying through gusts will be used alongside wind tunnel testing of artificial wings to discover what features of a bird’s wing help to alleviate gusts. The third track develops novel force and flow sensor arrays for autonomous flight control based on the sensor arrays found in flying animals. These arrays will be used to make UAVs with increased agility and robustness. This unique bird inspired approach uses biology to show what is possible, and engineering to find the features that enable this performance and develop them into functional technologies.
Max ERC Funding
1 998 546 €
Duration
Start date: 2016-04-01, End date: 2021-03-31
Project acronym CORREL-CT
Project Correlative tomography
Researcher (PI) Philip Withers
Host Institution (HI) THE UNIVERSITY OF MANCHESTER
Call Details Advanced Grant (AdG), PE8, ERC-2015-AdG
Summary Proposal summary (half page)
The vision is firstly, to develop correlative tomography to radically increase the nature and level of information (morphological, structural and chemical) that can be obtained for a 3D volume of interest (VoI) deep within a material or component by coupling non-destructive (3D+time) X-ray tomography with destructive (3D) electron tomography and, secondly to exploit this new approach to shed light on damage accumulation processes arising under demanding conditions. Successful completion of this project will provide new 3D & 4D insights across many areas and yield key experimental data for multiscale models.
Objective 1: To build the capability of correlative tomography
- To connect platforms across scales and modalities in order to track a VoI that may be located deep below the surface and to combine multiple techniques within a single platform.
- To add new facets to correlative tomography including
+ 3D chemical imaging
+ 3D crystal grain mapping
+ the local stress distribution
+ mechanical performance mapping at the VoI scale
Objective 2: To apply it to gain new insights into damage accumulation
Correlative tomography will provide a much richer multi-faceted hierarchical picture of materials behaviour from life science to food science from geology to cultural heritage. This project will focus specifically on identifying the nucleation, propagation and aggregation of damage processes in engineering materials.
- We will identify and track the mechanisms that control the progressive degradation of conventional bulk engineering materials operating under demanding conditions.
- We will examine the hierarchical strategies nature uses to control failure in natural materials through heterogeneous chemistry, morphology and properties. Alongside this we will examine the behaviour of man-made nano-structured analogues and whether we can exploit some of these strategies.
Summary
Proposal summary (half page)
The vision is firstly, to develop correlative tomography to radically increase the nature and level of information (morphological, structural and chemical) that can be obtained for a 3D volume of interest (VoI) deep within a material or component by coupling non-destructive (3D+time) X-ray tomography with destructive (3D) electron tomography and, secondly to exploit this new approach to shed light on damage accumulation processes arising under demanding conditions. Successful completion of this project will provide new 3D & 4D insights across many areas and yield key experimental data for multiscale models.
Objective 1: To build the capability of correlative tomography
- To connect platforms across scales and modalities in order to track a VoI that may be located deep below the surface and to combine multiple techniques within a single platform.
- To add new facets to correlative tomography including
+ 3D chemical imaging
+ 3D crystal grain mapping
+ the local stress distribution
+ mechanical performance mapping at the VoI scale
Objective 2: To apply it to gain new insights into damage accumulation
Correlative tomography will provide a much richer multi-faceted hierarchical picture of materials behaviour from life science to food science from geology to cultural heritage. This project will focus specifically on identifying the nucleation, propagation and aggregation of damage processes in engineering materials.
- We will identify and track the mechanisms that control the progressive degradation of conventional bulk engineering materials operating under demanding conditions.
- We will examine the hierarchical strategies nature uses to control failure in natural materials through heterogeneous chemistry, morphology and properties. Alongside this we will examine the behaviour of man-made nano-structured analogues and whether we can exploit some of these strategies.
Max ERC Funding
2 926 425 €
Duration
Start date: 2016-11-01, End date: 2021-10-31
Project acronym EPITOOLS
Project Chemical biology approaches to unraveling the histone code
Researcher (PI) Akane Kawamura
Host Institution (HI) THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Call Details Starting Grant (StG), LS9, ERC-2015-STG
Summary Posttranslational modifications on histones play crucial roles in the epigenetic regulation of eukaryotic gene expression. Chemical modifications that occur on histone tails include acetylation, methylation, phosphorylation, ubiquitination, and SUMOylation. This chemical diversity together with the positions and combinations of these modifications give rise to complex networks of highly controlled gene expression programs. The identification and characterisation of chromatin-associated proteins (or epigenetic regulators) in recent years has advanced our understanding of the significance of these histone modifications and the regulatory outcomes in development and in disease.
The project aims to generate new classes of highly selective and potent chemical probes for epigenetic regulators, focusing on enzymes and proteins associated with methyl-lysine marks. A novel modified peptide-based discovery platform, which combines molecular, chemical, biophysical and cellular techniques, will be developed and applied. These chemical probes will be useful for biological and biomedical research, and will serve as potential starting points for therapeutic epigenetic intervention.
Summary
Posttranslational modifications on histones play crucial roles in the epigenetic regulation of eukaryotic gene expression. Chemical modifications that occur on histone tails include acetylation, methylation, phosphorylation, ubiquitination, and SUMOylation. This chemical diversity together with the positions and combinations of these modifications give rise to complex networks of highly controlled gene expression programs. The identification and characterisation of chromatin-associated proteins (or epigenetic regulators) in recent years has advanced our understanding of the significance of these histone modifications and the regulatory outcomes in development and in disease.
The project aims to generate new classes of highly selective and potent chemical probes for epigenetic regulators, focusing on enzymes and proteins associated with methyl-lysine marks. A novel modified peptide-based discovery platform, which combines molecular, chemical, biophysical and cellular techniques, will be developed and applied. These chemical probes will be useful for biological and biomedical research, and will serve as potential starting points for therapeutic epigenetic intervention.
Max ERC Funding
1 758 846 €
Duration
Start date: 2016-04-01, End date: 2021-03-31
Project acronym ExtendGlass
Project Extending the range of the glassy state: Exploring structure and property limits in metallic glasses
Researcher (PI) Alan Lindsay GREER
Host Institution (HI) THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Call Details Advanced Grant (AdG), PE8, ERC-2015-AdG
Summary Metallic glasses (MGs), among the most actively studied metallic materials, have attractive mechanical properties (high elastic limit) but show work-softening and lack ductility. Recent work suggests the as-cast state of MGs can be much altered by thermomechanical treatments: rejuvenation (to higher energy) offers improved plasticity (perhaps even desirable work-hardening); relaxation (to lower energy) offers access to ultrastable states. Work of the PI has just shown that even simple thermal cycling can induce rejuvenation comparable with that from heavy plastic deformation, while elastic stress cycling can accelerate annealing. The research aims to extend the range of glassy states and to explore the consequences of unusual states, particularly for mechanical properties and for phase stability/crystallization. One possible limit to rejuvenation is the onset of fast crystallization. This regime will be studied for its relevance to crystallization of melts of low glass-forming ability, of interest to fill a gap in existing crystal-growth theory and for application in phase-change memory. Nine work-packages address these and further issues: exploitation of inhomogeneity in MGs to improve properties and enable processing, e.g. to permit stress relief without accompanying undesirable embrittlement; probing the maximum extent of anisotropy in MGs and the links between anisotropic structure and flow. Complementing the many mechanical and structural studies, molecular-dynamics simulations will be used to identify local events relating to rejuvenation/relaxation, to characterize (at atomic level) the anisotropy induced by anelastic strain and viscoplastic flow, to characterize the processes at the solid/liquid interface in pure-metal systems to understand crystal-growth mechanisms, especially why growth of ccp metals is so fast (and glass-forming ability very low). From preliminary results, it is expected that properties can be widened much beyond those of as-cast MGs.
Summary
Metallic glasses (MGs), among the most actively studied metallic materials, have attractive mechanical properties (high elastic limit) but show work-softening and lack ductility. Recent work suggests the as-cast state of MGs can be much altered by thermomechanical treatments: rejuvenation (to higher energy) offers improved plasticity (perhaps even desirable work-hardening); relaxation (to lower energy) offers access to ultrastable states. Work of the PI has just shown that even simple thermal cycling can induce rejuvenation comparable with that from heavy plastic deformation, while elastic stress cycling can accelerate annealing. The research aims to extend the range of glassy states and to explore the consequences of unusual states, particularly for mechanical properties and for phase stability/crystallization. One possible limit to rejuvenation is the onset of fast crystallization. This regime will be studied for its relevance to crystallization of melts of low glass-forming ability, of interest to fill a gap in existing crystal-growth theory and for application in phase-change memory. Nine work-packages address these and further issues: exploitation of inhomogeneity in MGs to improve properties and enable processing, e.g. to permit stress relief without accompanying undesirable embrittlement; probing the maximum extent of anisotropy in MGs and the links between anisotropic structure and flow. Complementing the many mechanical and structural studies, molecular-dynamics simulations will be used to identify local events relating to rejuvenation/relaxation, to characterize (at atomic level) the anisotropy induced by anelastic strain and viscoplastic flow, to characterize the processes at the solid/liquid interface in pure-metal systems to understand crystal-growth mechanisms, especially why growth of ccp metals is so fast (and glass-forming ability very low). From preliminary results, it is expected that properties can be widened much beyond those of as-cast MGs.
Max ERC Funding
2 434 090 €
Duration
Start date: 2016-10-01, End date: 2021-09-30
Project acronym ExtreFlow
Project Extreme deformation of structured fluids and interfaces. Exploiting ultrafast collapse and yielding phenomena for new processes and formulated products
Researcher (PI) Valeria Garbin
Host Institution (HI) IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Call Details Starting Grant (StG), PE8, ERC-2014-STG
Summary The increasing demand for environmentally friendly, healthier, and better performing formulated products means that the process industry needs more than ever predictive models of formulation performance for rapid, effective, and sustainable screening of new products. Processing flows and end use produce deformations that are extreme compared to what is accessible with existing experimental methods. As a consequence, the effects of extreme deformation are often overlooked without justification.
Extreme deformation of structured fluids and soft materials is an unexplored dynamic regime where unexpected phenomena may emerge. New flow-induced microstructures can arise due to periodic forcing that is much faster than the relaxation timescale of the system, leading to collective behaviors and large transient stresses.
The goal of this research is to introduce a radically innovative approach to explore and characterize the regime of extreme deformation of structured fluids and interfaces. By combining cutting-edge techniques including acoustofluidics, microfluidics, and high-speed imaging, I will perform pioneering high-precision measurements of macroscopic stresses and evolution of the microstructure. I will also explore strategies to exploit the phenomena emerging upon extreme deformation (collapse under ultrafast compression, yielding) for new processes and for adding new functionality to formulated products.
These experimental results, complemented by discrete particle simulations and continuum-scale modeling, will provide new insights that will lay the foundations of the new field of ultrafast soft matter. Ultimately the results of this research program will guide the development of predictive tools that can tackle the time scales of realistic flow conditions for applications to virtual screening of new formulations.
Summary
The increasing demand for environmentally friendly, healthier, and better performing formulated products means that the process industry needs more than ever predictive models of formulation performance for rapid, effective, and sustainable screening of new products. Processing flows and end use produce deformations that are extreme compared to what is accessible with existing experimental methods. As a consequence, the effects of extreme deformation are often overlooked without justification.
Extreme deformation of structured fluids and soft materials is an unexplored dynamic regime where unexpected phenomena may emerge. New flow-induced microstructures can arise due to periodic forcing that is much faster than the relaxation timescale of the system, leading to collective behaviors and large transient stresses.
The goal of this research is to introduce a radically innovative approach to explore and characterize the regime of extreme deformation of structured fluids and interfaces. By combining cutting-edge techniques including acoustofluidics, microfluidics, and high-speed imaging, I will perform pioneering high-precision measurements of macroscopic stresses and evolution of the microstructure. I will also explore strategies to exploit the phenomena emerging upon extreme deformation (collapse under ultrafast compression, yielding) for new processes and for adding new functionality to formulated products.
These experimental results, complemented by discrete particle simulations and continuum-scale modeling, will provide new insights that will lay the foundations of the new field of ultrafast soft matter. Ultimately the results of this research program will guide the development of predictive tools that can tackle the time scales of realistic flow conditions for applications to virtual screening of new formulations.
Max ERC Funding
1 499 186 €
Duration
Start date: 2015-05-01, End date: 2020-04-30
Project acronym FAKIR
Project Focal Adhesion Kinetics In nanosurface Recognition
Researcher (PI) Nikolaj Gadegaard
Host Institution (HI) UNIVERSITY OF GLASGOW
Call Details Consolidator Grant (CoG), LS9, ERC-2014-CoG
Summary The provision of advanced functional materials in the area of regenerative medicine and discovery applications depends on many different factors to provide the appropriate targeted function. As adherent cells also read their environment through substrate interactions there is a great interest in developing such substrates in a predictable manner. Their first point of contact is through their focal adhesions and it is also though them that forces are applied allowing the cell to migrate and establish cytoskeletal tension which in turn regulates cell function. The objective of this project is to investigate the cell-substrate interaction at the nanoscale and correlate that to the surface topography for predictable biomaterials. Through the application of state-of-the-art nanofabrication we will fabricate precise surface topographies with length scales comparable to the structural units found in the focal adhesions. The aim is to map and understand the topographical influence in the architectural arrangement of the proteins in the adhesions. Aided by high resolution microscopy we will classify cell types on different nanotopographies. Combining that information with machine learning, we will be able to gain information about cell characteristics from the rule set. That information can also be used in reverse to identify cell types with the previously defined characteristic. This approach is similar to face recognition seen on cameras and mobile phones.
The proposed research project will not only provide insight to an area of biomaterials not previously explored, yet aim to provide a blueprint for future design of biomaterials.
Summary
The provision of advanced functional materials in the area of regenerative medicine and discovery applications depends on many different factors to provide the appropriate targeted function. As adherent cells also read their environment through substrate interactions there is a great interest in developing such substrates in a predictable manner. Their first point of contact is through their focal adhesions and it is also though them that forces are applied allowing the cell to migrate and establish cytoskeletal tension which in turn regulates cell function. The objective of this project is to investigate the cell-substrate interaction at the nanoscale and correlate that to the surface topography for predictable biomaterials. Through the application of state-of-the-art nanofabrication we will fabricate precise surface topographies with length scales comparable to the structural units found in the focal adhesions. The aim is to map and understand the topographical influence in the architectural arrangement of the proteins in the adhesions. Aided by high resolution microscopy we will classify cell types on different nanotopographies. Combining that information with machine learning, we will be able to gain information about cell characteristics from the rule set. That information can also be used in reverse to identify cell types with the previously defined characteristic. This approach is similar to face recognition seen on cameras and mobile phones.
The proposed research project will not only provide insight to an area of biomaterials not previously explored, yet aim to provide a blueprint for future design of biomaterials.
Max ERC Funding
2 128 895 €
Duration
Start date: 2015-08-01, End date: 2020-07-31
Project acronym GADGET
Project Geometry and Anomalous Dynamic Growth of Elastic instabiliTies
Researcher (PI) Dominic Vella
Host Institution (HI) THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Call Details Starting Grant (StG), PE8, ERC-2014-STG
Summary Elastic instabilities are ubiquitous, from the wrinkles that form on skin to the ‘snap-through’ of an umbrella on a windy day. The complex patterns such instabilities make, and the great speed with which they develop, have led to a host of technological and scientific applications. However, recent experiments have revealed significant gaps in our theoretical understanding of such instabilities, particularly in the roles played by geometry and dynamics. I will establish a group to develop and validate a theoretical framework within which these results can be understood. Central to my approach is an appreciation of the crucial role of geometry in the pattern formation and dynamics of elastic instabilities.
As a starting point, I will consider the model problem of a pressurized elastic shell subject to a geometrically large deformation. This system develops either wrinkles or a stress-focusing instability depending on the internal pressure. As such, this is a natural paradigm with which to understand geometrical features of deformation relevant across length scales from deformed viruses to the subduction zones in Earth’s tectonic plates. My team will combine theoretical and computational approaches with tabletop experiments to determine a new set of shell deformations that are generically observed in contradiction of the classic ‘mirror buckling’. Understanding why these new shapes emerge will transform our perception of shell instabilities and provide new fundamental building blocks with which to model them. These ideas will also be used to transform our understanding of a number of other, previously mysterious, elastic instabilities of practical interest. Turning our focus to the dynamics of instabilities such as the snap-through of shells, we will show that accounting for geometry is again crucial. The new insight gained through this project will increase our ability to control elastic instabilities, benefitting a range of technological and scientific applications.
Summary
Elastic instabilities are ubiquitous, from the wrinkles that form on skin to the ‘snap-through’ of an umbrella on a windy day. The complex patterns such instabilities make, and the great speed with which they develop, have led to a host of technological and scientific applications. However, recent experiments have revealed significant gaps in our theoretical understanding of such instabilities, particularly in the roles played by geometry and dynamics. I will establish a group to develop and validate a theoretical framework within which these results can be understood. Central to my approach is an appreciation of the crucial role of geometry in the pattern formation and dynamics of elastic instabilities.
As a starting point, I will consider the model problem of a pressurized elastic shell subject to a geometrically large deformation. This system develops either wrinkles or a stress-focusing instability depending on the internal pressure. As such, this is a natural paradigm with which to understand geometrical features of deformation relevant across length scales from deformed viruses to the subduction zones in Earth’s tectonic plates. My team will combine theoretical and computational approaches with tabletop experiments to determine a new set of shell deformations that are generically observed in contradiction of the classic ‘mirror buckling’. Understanding why these new shapes emerge will transform our perception of shell instabilities and provide new fundamental building blocks with which to model them. These ideas will also be used to transform our understanding of a number of other, previously mysterious, elastic instabilities of practical interest. Turning our focus to the dynamics of instabilities such as the snap-through of shells, we will show that accounting for geometry is again crucial. The new insight gained through this project will increase our ability to control elastic instabilities, benefitting a range of technological and scientific applications.
Max ERC Funding
1 361 077 €
Duration
Start date: 2015-04-01, End date: 2020-03-31
Project acronym HAZE
Project Reducing the Burden of Smouldering Megafires: an Earth-Scale Challenge
Researcher (PI) Guillermo Jose Rein
Host Institution (HI) IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Call Details Consolidator Grant (CoG), PE8, ERC-2015-CoG
Summary Smouldering megafires are the largest and longest-burning fires on Earth. They destroy essential peatland ecosystems, and are responsible for 15% of annual global greenhouse gas emissions. This is the same amount attributed to the whole of the European Union, and yet it is not accounted for in global carbon budgets. Peat fires also induce surges of respiratory emergencies in the population and disrupt shipping and aviation routes for long periods, weeks even months. The ambition of HAZE is to advance the science and create the technology that will reduce the burden of smouldering fires. Despite their importance, we do not understand how smouldering fires ignite, spread or extinguish, which impedes the development of any successful mitigation strategy. Megafires are routinely fought across the globe with techniques that were developed for flaming fires, and are thus ineffective for smouldering. Moreover, the burning of deep peat affects older soil carbon that has not been part of the active carbon cycle for centuries to millennia, and thus creates a positive feedback to the climate system. HAZE wants to turn the challenges faced by smouldering research into opportunities and has the following three novel aims:
1) To conduct controlled laboratory experiments and discover how peat fires ignite, spread and extinguish.
2) To develop multidimensional computational models for the field scale (~1 km) and simulate the real phenomena.
3) To create pathways for novel mitigation technologies in accurate prevention, quick detection systems, and simulation-driven suppression strategies.
With my proposal, Europe has the chance to lead the way and pioneer technologies against this Earth-scale and important but unconventional source of emissions. I am confident that with the support of ERC, I can deliver the science and excellence needed to tackle this global challenge, and in doing so, I will advance the knowledge frontier, foster innovation and develop new young talent for Europe
Summary
Smouldering megafires are the largest and longest-burning fires on Earth. They destroy essential peatland ecosystems, and are responsible for 15% of annual global greenhouse gas emissions. This is the same amount attributed to the whole of the European Union, and yet it is not accounted for in global carbon budgets. Peat fires also induce surges of respiratory emergencies in the population and disrupt shipping and aviation routes for long periods, weeks even months. The ambition of HAZE is to advance the science and create the technology that will reduce the burden of smouldering fires. Despite their importance, we do not understand how smouldering fires ignite, spread or extinguish, which impedes the development of any successful mitigation strategy. Megafires are routinely fought across the globe with techniques that were developed for flaming fires, and are thus ineffective for smouldering. Moreover, the burning of deep peat affects older soil carbon that has not been part of the active carbon cycle for centuries to millennia, and thus creates a positive feedback to the climate system. HAZE wants to turn the challenges faced by smouldering research into opportunities and has the following three novel aims:
1) To conduct controlled laboratory experiments and discover how peat fires ignite, spread and extinguish.
2) To develop multidimensional computational models for the field scale (~1 km) and simulate the real phenomena.
3) To create pathways for novel mitigation technologies in accurate prevention, quick detection systems, and simulation-driven suppression strategies.
With my proposal, Europe has the chance to lead the way and pioneer technologies against this Earth-scale and important but unconventional source of emissions. I am confident that with the support of ERC, I can deliver the science and excellence needed to tackle this global challenge, and in doing so, I will advance the knowledge frontier, foster innovation and develop new young talent for Europe
Max ERC Funding
1 958 900 €
Duration
Start date: 2016-05-01, End date: 2021-04-30
