ERC FUNDED PROJECTS

OPPSEXRIGHTS will be the first large-scale, transnational study to consider the effects of recent Sexual and Gender Rights and Equalities (SGRE) on those who oppose them, by exploring opponents’ experiences of the transformation of everyday spaces. It will work beyond contemporary polarisations, creating new possibilities for social transformation. This cutting-edge research engages with the dramatically altered social and political landscapes in the late 20th and early 21st Century created through the development of lesbian, gay, bisexual, and trans, and women’s rights. Recent reactionary politics highlight the pressing need to understand the position of those who experience these new social orders as a loss. The backlash to SGRE has coalesced into various resistances that are tangibly different to the classic vilification of homosexuality, or those that are anti-woman. Some who oppose SGRE have found themselves the subject of public critique; in the workplace, their jobs threatened, while at home, engagements with schools can cause family conflicts. This is particularly visible in the case studies of Ireland, UK and Canada because of SGRE. A largescale transnational systematic database will be created using low risk (media and organisational discourses; participant observation at oppositional events) and higher risk (online data collection and interviews) methods. Experimenting with social transformation, OPPSEXRIGHTS will work to build bridges between ‘enemies’, including families and communities, through innovative discussion and arts-based workshops. This ambitious project has the potential to create tangible solutions that tackle contemporary societal issues, which are founded in polarisations that are seemingly insurmountable.

1 988 652 €

Start date: 2019-10-01, End date: 2024-09-30

Early Medieval Irish literature (7th–10th centuries) is vast in extent and rich in genres, but owing to its mostly anonymous transmission, for most texts the precise time and circumstances of composition are unknown. Unless where texts contain historical references, the only clues for a rough chronological positioning of the texts are to be found in their linguistic peculiarities. Phonology, morphology, syntax and the lexicon of the Irish language changed considerably from Early Old Irish (7th c.) into Middle Irish (c. 10th–12th centuries). However, only the relative sequence of changes is well understood; for most sound changes very few narrow dates have been proposed so far. It is the aim of Chronologicon Hibernicum to find a common solution for both problems: through the linguistic profiling of externally dated texts (esp. annalistic writing and sources with a clear historical anchorage) and through serialising the emerging linguistic and chronological data, progress will be made in assigning dates to the linguistic changes. Groundbreakingly, this will be done by using statistical methods for the seriation of the data, and for estimating dates using Bayesian inference. The resultant information will then be used to find new dates for hitherto undated texts. On this basis, a much tighter chronological framework for the developments of the Early Medieval Irish language will be created. In a further step it will be possible to arrive at a better chronological description of medieval Irish literature as a whole, which will have repercussions on the study of the history and cultural and intellectual environment of medieval Ireland and on its connections with the wider world. The data collected and analysed in this project will form the database Chronologicon Hibernicum which will serve as the authoritative guideline and reference point for the linguistic dating of Irish texts. In the future, the methodology will be transferable to other languages.

1 804 230 €

Start date: 2015-09-01, End date: 2020-08-31

Understanding the coordination of attitudes in societies is vitally important for many disciplines and global social challenges. Network opinion dynamics are poorly understood, especially in hybrid networks where automated (bot) agents seek to influence economic or political processes (e.g. USA: Trump vs Clinton; UK: Brexit). A dynamic fixing theory of attitudes is proposed, premised on three features of attitudes demonstrated in ethnomethodology and social psychology; that people: 1) simultaneously hold a repertoire of multiple (sometimes ambivalent) attitudes, 2) express attitudes to enact social identity; and 3) are accountable for attitude expression in interaction. It is proposed that interactions between agents generate symbolic links between attitudes with the emergent social-symbolic structure generating perceived ingroup similarity and outgroup difference in a multilayer network. Thus attitudes can become dynamically fixed when constellations of attitudes are locked-in to identities via multilayer networks of attitude agreement and disagreement; a process intensified by conflict, threat or zero-sum partisan processes (e.g. elections/referenda). Agent-based simulations will validate the theory and explore the hypothesized channels of bot influence. Network experiments with human and hybrid networks will test theoretically derived hypotheses. Observational network studies will assess model fit using historical Twitter data. Results will provide a social-psychological-network theory for attitude dynamics and vulnerability to computational propaganda in hybrid networks. The theory will explain: (a) when and how consensus can propagate rapidly through networks (since identity processes fix attitudes already contained within repertoires); (b) limits of identity-related attitude propagation (since attitudes outside of repertoires will not be easily adopted); and (c) how attitudes can often ‘roll back’ after events (since contextual changes ‘unfix’ attitudes).

1 499 925 €

Start date: 2018-12-01, End date: 2023-11-30

This proposal seeks support for a research group led by James Heckman of the Geary Institute at University College Dublin to produce an integrated developmental approach to health that studies the origins and the evolution of health inequalities over the lifecourse and across generations, and the role played by cognition, personality, genes, and environments. Major experimental and nonexperimental international datasets will be analyzed. A practical guide to implementing related policy will be produced. We will build a science of human development that draws on, extends, and unites research on the biology and epidemiology of health disparities with medical economics and the economics of skill formation. The goal is to develop an integrated framework to jointly model the economic, social and biological mechanisms that produce the evolution and the intergenerational transmission of health and of the capabilities that foster health. The following tasks will be undertaken: (1) We will quantify the importance of early-life conditions in explaining the existence of health disparities across the lifecourse. (2) We will understand how health inequalities are transmitted across generations. (3) We will assess the health benefits from early childhood interventions. (4) We will examine the role of genes and environments in the aetiology and evolution of disease. (5) We will analyze how health inequalities emerge and evolve across the lifecourse. (6) We will give biological foundations to both our models and the health measures we will use. The proposed research will investigate causal channels for promoting health. It will compare the relative effectiveness of interventions at various stages of the life cycle and the benefits and costs of later remediation if early adversity is not adequately eliminated. It will guide the design of current and prospective experimental and longitudinal studies and policy formulation, and will train young scholars in frontier methods of research

2 505 222 €

Start date: 2011-05-01, End date: 2016-04-30

Obesity has reached epidemic proportions globally. At least 2.8 million people die each year as a result of being overweight or obese, the biggest burden being obesity-related diseases. It is now clear that inflammation is an underlying cause or contributor to many of these diseases, including type 2 diabetes, atherosclerosis, and cancer. Recognition that the immune system can regulate metabolic pathways has prompted a new way of thinking about diabetes and weight management. Despite much recent progress, most immunometabolic pathways, and how to target them, are currently unknown. One such pathway is the cross-talk between invariant natural killer (iNKT) cells and neighboring adipocytes. iNKT cells are the innate lipid-sensing arm of the immune system. Since our discovery that mammalian adipose tissue is enriched for iNKT cells, we have identified a critical role for iNKT cells in regulating adipose inflammation and body weight. The goal of this project is to use a multi-disciplinary approach to identify key signals and molecules used by iNKT cells to induce metabolic control and weight loss in obesity. Using immunological assays and multi-photon intravital microscopy, cells and pathways that control the unique regulatory functions of adipose iNKT cells will be identified and characterised. Novel lipid antigens in adipose tissue will be identified using a biochemical approach, perhaps explaining iNKT cell conservation in adipose depots, and providing safe tools for iNKT cell manipulation in vivo. Finally, using proteomics and whole body metabolic analysis in vivo, novel ‘weight-loss inducing’ factors produced by adipose iNKT cells will be identified. This ambitious and high impact project has the potential to yield major insights into immunometabolic interactions at steady state and in obesity. The ability to activate or induce adipose iNKT cells holds remarkable potential as an entirely new therapeutic direction for treating obesity and type 2 diabetes.

1 804 052 €

Start date: 2016-09-01, End date: 2021-08-31

FOODCULT is the first project to establish both the fundamentals of everyday diet, and the cultural ‘meaning’ of food and drink, in early modern Ireland. Exploring the period 1550-1650, one of major economic development, unprecedented intercultural contact, but also of conquest, colonisation and war, it focusses on Ireland as a case-study for understanding the role of food in the demonstration and negotiation of authority and power, and as a site for the development of emergent ‘national’ food cultures. Moving well beyond the colonial narrative of Irish social and economic development, however, it enlarges the study of food to examine neglected themes in Irish historiography, including gender, class, kinship and religious identities, as expressed through the consumption and exchange of food and drink. Taking advantage of recent archaeological discoveries and the unprecedented accessibility of the archaeological evidence, the project develops a ground-breaking interdisciplinary approach, merging micro-historical analytical techniques with science and experimental archaeology, to examine what was eaten, where, why and by whom, at a level of detail deemed impossible for Irish history. Such questions will be explored in a comparative British Isles context, situating Irish developments within a broader analytical framework, whilst moving English food historiography beyond its current insular focus. As a corollary, the project will produce the first major database of diet-related archaeological evidence for this period Mapping Diet: Comparative Food-Ways in Early Modern Ireland, while making accessible the only existing household accounts, a hugely significant, and previously overlooked, quantitative and qualitative source for dietary trends. These resources will shed light, not just on consumption patterns, but on Ireland’s broader economic and social development, whilst significantly furthering research agendas in early modern historical and archaeological scholarship.

1 433 133 €

Start date: 2019-02-01, End date: 2024-01-31

Financialisation, or the growing power of finance over societies and economies, is increasingly recognised as the key feature of contemporary capitalism. However, significant gaps in our understanding of this process remain. Indeed, despite growing recognition that financialisation is an inherently spatial process, a geographically-informed view of financialisation remains underdeveloped. In addition, and related to this, the extent and the ways in which post-socialist ‘transition’ societies in East-Central Europe have been financialised remain under-researched and under-theorised. Yet, the examination of former state-socialist societies (built on the very opposite economic logic to that of financialisation) provides an unmatched opportunity to learn about financialisation itself, how it ‘penetrates’ societies and with what social and spatial implications. East-Central Europe in this sense constitutes a unique terrain for frontier research. GEOFIN will address the above shortcomings by producing empirical and theoretical insights to develop a geographically-informed view of financialisation. The objective is to examine how states, banks and households in post-socialist contexts have been financialised and to consider what implications this has for the societies in question and for Europe as a whole. The project will pilot a novel approach based on the concept of ‘financial chains’ which are understood both as channels of value transfer and as social relations that shape socio-economic processes and attendant economic geographies. A set of interlocking case studies will be mobilised to reveal the different ways in which banks, states and households across post-socialist East-Central Europe are interconnected by financial chains with each other and with a wider political economy. GEOFIN will fundamentally advance our understanding of new geographies of financialisation, opening up new horizons in studies of finance and its future role in the society.

1 806 536 €

Start date: 2016-12-01, End date: 2021-11-30

The European public square has, in the last twenty years and increasingly so, been inundated with controversies around the place of religion in the public sphere. Issues such as freedom of religious expression, freedom of speech v. blasphemy, and the public display of religious symbols loom large in the workplace, in schools, in media coverage etc., at the local, national, and supranational level. The presence of Islam has been a catalyst for many debates on religion in Europe, but these have now grown to encompass much broader assumptions about the nature of religious communities, their relationship to state institutions, and the place of minority religious communities in society. Against this backdrop the European Court of Human Rights (ECtHR) adds its own voice and significantly influences the terms of the debates. This project examines the domestic impact of the ECtHR religion case law: it explores the mobilisation of local and national level actors in the wake of a number of high-profile ECtHR religious freedom cases in order to determine the nature and extent of European juridical influence on religious pluralism. In light of scholarly debates questioning the direct effects of courts, the project probes developments that take place ‘in the shadow’ of the Court. It engages especially with the extent to which court decisions define the ‘political opportunity structures’ and the discursive frameworks within which citizens act. What is the aftermath of the Court’s religion jurisprudence in terms of its applications at the grassroots level? The question is important because ECtHR case law will shape, to a large extent, both local and national level case law and – less conspicuously but no less importantly – grassroots developments in the promotion of or resistance to religious pluralism. Both the latter will, in turn, influence the future of the ECtHR caseload. The project will thus impart rare insight into directions being taken in religious pluralism in Europe.

1 184 568 €

Start date: 2014-01-01, End date: 2018-12-31

Schizophrenia, affecting 0.5-1% of the population, is ranked by the World Health Organisation as more disabling than paraplegia or blindness in 18-34 year olds. Current treatments, developed over 50 years ago, are only partly effective in treating this disability, and new treatments are lacking. To address this treatment impasse, this project aims to develop and test a novel immune based model of deficits in social cognition – the set of mental operations that underlie social interactions (e.g. emotion recognition, theory of mind) and strongly predict social disability in schizophrenia. Based on recent discoveries in schizophrenia genetics, this project asks: (1) are genetic causes of deficits in social cognition mediated by effects on immune function during development and (2) does early social environment moderate these effects? To address these questions, the project has two parts. Part A focuses on neuropsychological and neuroimaging studies of social cognition in patients and healthy adults so as to (1) provide an innovative characterisation of the effects of inflammatory markers (e.g. pro-/anti- inflammatory cytokines) on social cognition, (2) establish whether these markers mediate the effects of recently identified genetic risk loci on schizophrenia, and (3) identify to what extent early social environment (e.g. parental relationships, childhood trauma) moderates this relationship. Part B focuses on behavioural and pharmacological studies in mice to (1) establish the causal effects of early immune challenge and early social environment on social cognition, and (2) test the translational benefits of anti-inflammatory treatment to normalize the resulting deficits. By validating an immune based model of schizophrenia, this project has the potential to move beyond current (dopamine based) treatments, and suggest groundbreaking alternatives for understanding and treating social disability in this and other neurodevelopmental disorders.

1 477 622 €

Start date: 2016-07-01, End date: 2021-06-30

The purpose of the proposed project is to think afresh about the violent aftermath of the Great War and its legacies. This will be achieved by forging a team of researchers who focus on the violent conflicts that erupted in many of the former combatant states after 1917/18 from a comparative or transnational global perspective and the ways in which these conflicts were avoided in other areas. The project will differ from previous attempts to analyse the violent transition from war to peace in this period in several ways: The first is its comparative and transational complexion. Despite recent attempts to write transnational histories of the Great War, the global history of its immediate aftermath is yet to be written. War and the politics of conflicts (and its aftermaths) are still largely studied according to divisions of national identity or ethnic difference. And yet clearly the First World War was a phenomenon that crossed frontiers and left legacies that posessed common themes. Indeed one of its consequences, especially in East-Central Europe but also in the shatter-zones of the Ottoman Empire and colonial contexts, was the destruction of frontiers, creating spaces without order or unquestioned government authority. The project will thus approach its subject matter by zones of victory, of defeat, and of mutilated or ambivalent victories rather than nation-states as a novel way of overcoming nation-centric frameworks of analysis. In terms of chronological scope, the investigation moves away from the traditional emphasis on the years 1914-18 as the crucible years of twentieth-century history. Furthermore, the project is at once European and global, investigating the emergence of violent conflicts in both the shatter-zones of European land empires and colonial conflicts.

1 199 386 €

Start date: 2009-09-01, End date: 2014-02-28

Mesenchymal cells (MCs) of the intestinal lamina propria refer to a variety of cell types, most commonly intestinal myofibroblasts, fibroblasts, pericytes, and mesenchymal stromal cells, which show many similarities in terms of origin, function and molecular markers. Understanding the physiological significance of MCs in epithelial and immunological homeostasis and the pathophysiology of chronic intestinal inflammatory and neoplastic disease remains a great challenge. In this proposal, we put forward the challenging hypothesis that, especially during acute or chronic inflammatory and tumorigenic conditions, MCs play important physiological roles in intestinal homeostasis regulating key processes such as epithelial damage, regeneration and tumorigenesis, intestinal inflammation and lymphoid tissue formation. We further posit that a unifying principle underlying such functions would be the innate character of MCs, which we hypothesize are capable of directly sensing and metabolizing innate signals from microbiota or cytokines in order to exert homeostatic epithelial and immunological regulatory functions in the intestine. We will be using genetic approaches to target innate pathways in MCs and state of the art phenotyping to discover the physiologically important signals orchestrating intestinal homeostasis in various animal models of intestinal pathophysiology. We will also study MC lineage relations and plasticity during disease and develop ways to interfere therapeutically with MC physiology to achieve translational added value for intestinal diseases, as well as for a range of other pathologies sharing similar characteristics.

2 590 000 €

Start date: 2014-07-01, End date: 2019-06-30

MicroRNAs (miRNAs) are important regulators of both innate and adaptive immunity. This is very much a frontier area since little is known about miRNA function in vivo, and there is still much discovery to be done. Their emerging functions indicate that they are as potent as cytokines in immunoregulation. We have found that Toll-like receptor (TLR) signaling is potently modulated by 2 particular miRNAs, miR-21 and miR-107. The programme will have 4 aspects which will build on this initial observation. 1. Extension of our observations on miR-21 and TLR signaling. We found that the translational repressor PDCD4 is a key target. We will study miR-21-deficient mice, construct a mouse model where the miR-21 seed sequence in the 3'UTR of PDCD4 is altered, and target miR-21 in vivo using antagomirs. We will also determine the mRNAs regulated by PDCD4 and examine the role of mTOR in PDCD4 control since PDCD4 is a possible substrate. 2. Examination of the role of miR-107 in TLR signaling. TLRs dramatically decrease it¿s expression. We have found that miR-107 has an inhibitory role in TNF secretion via the targeting of CDK6. Activation of PPAR-alpha increases expression of miR107, which could be part of the anti-inflammatory effect of PPAR-alpha ligands. We will explore miR-107-deficient mice and in vitro models of miR-107 function. 3. Exploring the targeting of miR-155 by IL10, which we have recently found. The miR-155 target SHIP1 may be important in this system. We will analyze this process in detail and determine other targets for miR-155 in IL10 action. 4. Perform a screen for novel regulators of the aforementioned miRNAs and screen for miRNAs as regulators of other innate immune pathways, including Nalp3 and RIG-I, about which little is known. These experiments will yield new insights and components The focus is the complex role miRNAs are playing in innate immunity and inflammation.

2 480 587 €

Start date: 2011-06-01, End date: 2016-05-31

How are European workplaces being transformed? What kinds of new social bargains are emerging across the European Union? How are they being institutionalised? How are new workplace bargains shaped by the broader politics of sectors, regions and national economies? These questions are crucial to the future of the European ‘social model’. The objective of this research programme is to provide answers to these questions, drawing on cross-national survey research on workplace organisation from 1995 to 2010 and selected industrial case studies in the small open European economies of Denmark, Ireland and the Netherlands. These questions also raise crucial theoretical issues. The research reformulates the core elements of the ‘Varieties of Capitalism’ framework that has dominated comparative political economy for the past decade (Hall and Soskice, 2001). It improves our understanding of the diverse organisation of capitalism in Europe, of how that diversity is rooted in politically constructed ‘pathways to the future’, and of how capitalism is constructed out of social and institutional capabilities across Europe.

1 320 020 €

Start date: 2012-01-01, End date: 2017-06-30

In allergic asthma, an important health problem, disease is driven by allergen-specific Th2 immune responses. Differentiation of Th2 cells depends on their early interactions with antigen presenting cells, such as dendritic cells (DCs), and cytokines are crucial for this process. Osteopontin (Opn) was originally identified as an important cytokine for Th1 immunity and autoimmunity. Our group recently demonstrated that Opn is highly expressed in the lungs of asthmatic patients and of mice with Th2-mediated allergic airway inflammation. Our work revealed anti-allergic effects of Opn on airway disease during secondary pulmonary antigenic challenge mediated by regulation of DC subsets. In addition, intranasal administration of recombinant Opn during pulmonary exposure to the allergen protected mice from allergic airway disease suppressing all features of disease, recruitment of Th2 cells and allergen-specific Th2 responses. Our previous experiments, as well as preliminary studies presented in this proposal, point to an important novel immunoregulatory role for Opn in the Th2 setting. However, most aspects of the Opn-mediated immune mechanism of protection remain unclear. With this proposal, we aim at elucidating the immunoregulatory/protective mechanisms of Opn utilizing immunologic, molecular and genomic approaches as well as in vivo mouse models of allergic airway inflammation. We propose to investigate the mechanisms mediating Opn-effects on: (1) DC subsets and Treg cells that confer protection during pulmonary allergen challenge (2) recruitment and function of allergen-specific Th2 (generated during sensitization) as well as of newly-activated Th effector cells and their interactions during pulmonary allergen challenge and (3) antigenic tolerance induction in the Th2 setting. The studies proposed here will provide new insight into the biology of Opn-dependent regulation of DC subsets, Th2 responses and DC-T cell interactions opening new important questions in im

1 511 200 €

Start date: 2009-12-01, End date: 2015-11-30

PRILA will create the first account of how mechanisms for securing rights, ensuring accountability and achieving adherence to the rule of law are experienced in European prisons. Prisons are places where considerable power differentials exist, and are unique sites for the expression of the values which underpin public and prison law. Systems to ensure that prisoners are treated fairly and that rights are upheld are essential to ensure that imprisonment is conducted in ways that are just and promote good order. These are fundamental principles of the ‘European’ way in penal policy and penal law. Existing accounts of the deployment of penal power overlook key elements of how accountability, the rule of law, and rights are experienced. PRILA will document how prisoners, prison staff, staff of accountability bodies experience structures for ensuring decisions and actions taken in prison are fair, transparent, consistent, subject to appeal and review, and in compliance with principles of human rights. In doing so, PRILA will transform and extend accounts of legitimacy in prisons, judicial review of administrative action, the pains of imprisonment, and understandings of how penal power is experienced. Drawing on the disciplines of public and prison law, human rights, comparative law, and the sociology of punishment, the project will utilise legal, qualitative and quantitative research methods to create an account of how ‘accountability work’ is experienced. It will also examine how accountability structures are manifestations of penal ideologies or types of prison regimes. The project will advance current judicial and legal conceptions of accountability, the rule of law, and fairness, by reference to how these concepts are experienced in practice, and examine whether and how they are distinctively ‘European’. The project will thereby support the creation of better penal policies and practices aimed at the protection of the rule of law and rights in the prison context.

1 428 343 €

Start date: 2016-04-01, End date: 2021-03-31

SeaLiT explores the transition from sail to steam navigation and its effects on seafaring populations in the Mediterranean and the Black Sea between the 1850s and the 1920s. In the core of the project lie the effects of technological innovation on seafaring people and maritime communities, whose lives were drastically altered by the advent of steam. The project addresses the changes through the actors, seafarers, shipowners and their families, focusing on the adjustment of seafaring lives to a novel socio-economic reality. It investigates the maritime labour market, the evolving relations among shipowner, captain, crew and their local societies, life on board and ashore, as well as the development of new business strategies, trade routes and navigation patterns. Maritime labour and shipping remains an understudied case of the transition from the premodern working environment of the sailing ship to that of the steamer, in a period of rapid technological improvements, economic growth and market integration. Therefore, the project will address a major gap in maritime historiography: on the one hand, the transition from sail to steam, and on the other, the Mediterranean and the Black Sea, “the extended Mediterranean” according to F. Braudel. The project examines in a comparative approach seven maritime regions: the Ionian, Aegean, Tyrrhenian, Adriatic and Black Seas, Spain and southern France. The research team composed of the PI, three postdoctoral fellows, four senior researchers and four Ph.D. candidates from Greece, Italy, Spain, France and Ukraine will study unpublished sources: ship logbooks, crew lists, business records, and private correspondence. They will produce a collective volume, several articles, a final synthesis by the PI, four Ph.D. dissertations, three workshops, one international conference and a website with an online open access database, an archival and bibliographical corpus and reconstruction of ship voyages on a web G.I.S. application.

1 372 350 €

Start date: 2017-02-01, End date: 2022-01-31

"Software is essential to the functioning of cities; a vital element in the operation and governance of travel, the built environment, consumption, work, home life, services and utilities. To date, analysis has focused on the technologies that software enables, rather than the actual code that renders the city programmable and knowable in new ways. We have thus failed to appreciate and understand a key mediator of urban change and city life. The project will provide a groundbreaking analysis of the emerging programmable city with respect to: (1) how the city is translated into software; (2) how software reshapes the city. It will examine these processes in relation to four key urban practices – how we understand, manage, work and live in the city. With respect to how cities are translated into software, the project will examine how cities and citizens are captured and processed as data; how ideas about city governance are composed into code; the geographies of software production; how software is discursively produced and legitimated by vested interests. With respect to how software reshapes cities, the project will examine: the rise of ‘big data’ and how data infrastructures and information systems are used to inform public policy development; how software is used to regulate and govern city life; how the activities and practices of work are being reshaped by computation; and how software transforms the spatiality and spatial behaviour of individuals. A range of methodologies will be employed, including interviews, ethnographies, audits, surveys, discourse analysis, and the development of a new method, algorithm archaeology. The project will address a serious lacuna in social science research by answering key questions concerning the nature of software and the changing production and management of cities and citizens. It will provide new theoretical tools and rich empirical evidence for thinking through the new era of programmable urbanism."

2 309 926 €

Start date: 2013-06-01, End date: 2018-05-31

The creation and accumulation of knowledge are processes at the heart of technological change and economic growth. Attention has been directed at aggregate measures of knowledge production in regional and national contexts, but little consideration has been given to the properties of knowledge produced in specific places. How does the nature of knowledge that is produced vary over space, what conditions the scope of technologies generated in different locations, and how do these knowledge sets impact the performance of local firms and industries? To date, the way in which specific regional knowledge capabilities influence the evolution of local technology trajectories and thus shape geographies of economic prosperity have not yet been considered systematically. The objective of the “Technology Evolution in Regional Economies” (TechEvo) project is to address these significant shortcomings. Focusing on the evolution of scientific and technical knowledge, as indicated by patent, trademark and scientific literature records, the point of departure is the pan-European knowledge space for all 28 European Union member countries, plus Norway and Switzerland, over the time period 1981-2015. The knowledge space, based on the co-occurrence matrix of particular knowledge domains (629), maps the proximity of patent technology classes and enables the development of regional measures of knowledge specialization for all 1,369 (NUTS3) regions. Set in an evolutionary framework the investigation provides ground breaking insights into how innovative entities and individual inventors are embedded in social and cognitive local and non-local networks, and how regional technology trajectories are shaped through entry, exit, and selection processes. TechEvo will provide a wealth of indicators, models and tools that will assist firms and policy makers in place-based investment decisions, and deliver a science and technology policy evaluation tool capable of assessing impact.

1 496 599 €

Start date: 2017-03-01, End date: 2022-02-28

"Traffic congestion is a serious threat for the economic and social life of modern societies as well as for the environment, which calls for drastic and radical solutions. The proposal puts forward an utterly original idea that leads to a novel paradigm for vehicular traffic in the era of connected and automated vehicles (CAVs) and is based on two combined principles. The first principle is lane-free traffic, which renders the driving task for CAVs smoother and safer, as risky lane-changing manoeuvres become obsolete; increases the static and dynamic capacity of the roadway due to increased road occupancy; and mitigates congestion-triggering manoeuvres. The second principle is the nudge effect, whereby vehicles may be ""pushing"" (from a distance, using sensors or communication) other vehicles in front of them; this allows for traffic flow to be freed from the anisotropy restriction, which stems from the fact that human driving is influenced only by downstream vehicles. The nudge effect may be implemented in various possible ways, so as to maximize the traffic flow efficiency, subject to safety and convenience constraints. TrafficFluid combines lane-free traffic with vehicle nudging to provide, for the first time since the automobile invention, the possibility to design (rather than merely describe or model) the traffic flow characteristics in an optimal way, i.e. to engineer the future CAV traffic flow as an efficient artificial fluid. To this end, the project will develop and deliver the necessary vehicle movement strategies for various motorway and urban road infrastructures, along with microscopic and macroscopic simulators and traffic management actions. TrafficFluid risk stems from the immense challenge of designing a new traffic system from scratch; however, we expect that the project will trigger a whole new path of international innovative research developments and testbeds that would pave the way towards a new efficient traffic system in the era of CAVs. "

2 495 500 €

Start date: 2019-10-01, End date: 2024-09-30