ERC FUNDED PROJECTS

Clouds play a key role in the climate system. Small anthropogenic perturbations of the cloud system potentially have large radiative effects. Aerosols perturb the global radiation budget directly, by scattering and absorption, as well as indirectly, by the modification of cloud properties and occurrence. The applicability of traditional conceptual models of indirect aerosol effects to convective clouds is disputed as cloud dynamics complicates the picture. Strong evidence for numerous aerosol effects on convection has been established in individual disciplines: through remote sensing and in-situ observations as well as by cloud resolving and global modelling. However, a coherent scientific view of the effects of aerosols on convection has yet to be established. The primary objective of ACCLAIM is to recast the effects of aerosols on convective clouds as basis for improved global estimates of anthropogenic climate effects. Specific objectives include: i) to unravel the governing principles of aerosol effects on convective clouds; ii) provide quantitative constraints on satellite-retrieved relationships between convective clouds and aerosols; and ultimately iii) to enable global climate models to represent the full range of anthropogenic climate perturbations and quantify the climate response to aerosol effects on convective clouds. I have developed the research strategy of ACCLAIM to overcome disciplinary barriers in this frontier research area and seek five years of funding to establish an interdisciplinary, physics focused, research group consisting of two PostDocs, two PhD students and myself. ACCLAIM will be centred around global aerosol-convection climate modelling studies, complemented by research constraining aerosol-convection interactions through remote sensing and a process focused research strand, advancing fundamental understanding and global model parameterisations through high resolution aerosol-cloud modelling in synergy with in-situ observations.

1 429 243 €

Start date: 2011-09-01, End date: 2017-02-28

AFRIGOS investigates the process of 'respacing' Africa, a political drive towards regional and continental integration, on the one hand, and the re-casting of Africa's engagement with the global economy, on the other. This is reflected in unprecedented levels of investment in physical and communications infrastructure, and the outsourcing of key functions of Customs, Immigration and security agencies. AFRIGOS poses the question of how far respacing is genuinely forging institutions that are facilitating or obstructing the movement of people and goods; that are enabling or preventing urban and border spaces from being more effectively and responsively governed; and that take into account the needs of African populations whose livelihoods are rooted in mobility and informality. The principal research questions are approached through a comparative study of port cities, border towns and other strategic nodes situated along the busiest transport corridors in East, Central, West and Southern Africa. These represent sites of remarkable dynamism and cosmopolitanism, which reflects their role in connecting African urban centres to each other and to other global cities. AFRIGOS considers how governance 'assemblages' are forged at different scales and is explicitly comparative. It works through 5 connected Streams that address specific questions: 1. AGENDA-SETTING is concerned with policy (re-)formulation. 2. PERIPHERAL URBANISM examines governance in border towns and port cities. 3. BORDER WORKERS addresses everyday governance emerging through the interaction of officials and others who make their livelihoods from the border. 4. CONNECTIVE INFRASTRUCTURE looks as the transformative effects of new technologies. 5. PEOPLE & GOODS IN MOTION traces the passage of people and goods and the regimes of regulation to which they are subjected. AFRIGOS contributes to interdisciplinary research on borderland studies, multi-level governance and the everyday state.

2 491 364 €

Start date: 2016-01-01, End date: 2020-12-31

Alkenones are algal lipids that have been used for decades to reconstruct quantitative past sea surface temperature. Although alkenones are being discovered in an increasing number of lake sites worldwide, only two terrestrial temperature records have been reconstructed so far. The development of this research field is limited by the lack of interdisciplinary research that combines modern biological and ecological algal research with the organic geochemical techniques needed to develop a quantitative biomarker (or molecular fossil) for past lake temperatures. More research is needed for alkenones to become a widely used tool for reconstructing past terrestrial temperature change. The early career Principal Investigator has discovered a new lake alkenone-producing species of haptophyte algae that produces alkenones in high abundances both in the environment and in laboratory cultures. This makes the new species an ideal organism for developing a culture-based temperature calibration and exploring other potential environmental controls. In this project, alkenone production will be manipulated, and monitored using state-of-the-art photobioreactors with real-time detectors for cell density, light, and temperature. The latest algal culture and isolation techniques that are used in microalgal biofuel development will be applied to developing the lake temperature proxy. The objectives will be achieved through the analysis of 90 new Canadian lakes to develop a core-top temperature calibration across a large latitudinal and temperature gradient (Δ latitude = 5°, Δ spring surface temperature = 9°C). The results will be used to assess how regional palaeo-temperature (Uk37), palaeo-moisture (δDwax) and palaeo-evaporation (δDalgal) respond during times of past global warmth (e.g., Medieval Warm Period, 900-1200 AD) to find an accurate analogue for assessing future drought risk in the interior of Canada.

940 883 €

Start date: 2015-04-01, End date: 2020-03-31

Methane, a key greenhouse gas, is cycled by microorganisms via two pathways, aerobically and anaerobically. Research on the marine methane cycle has mainly concentrated on anaerobic processes. Recent biomarker work has provided compelling evidence that aerobic methane oxidation (AMO) can play a more significant role in cycling methane emitted from sediments than previously considered. AMO, however, is not well studied requiring novel proxies that can be applied to the sedimentary record. A group of complex lipids biosynthesised by aerobic methanotrophs known as aminobacteriohopanepolyols represent an ideal target for developing such poxies. Recently BHPs have been identified in a wide range of modern and recent environments including a continuous record from the Congo deep sea fan spanning the last 1.2 million years. In this integrated study, the regulation and expression of BHP will be investigated and calibrated against environmental variables including temperature, pH, salinity and, most importantly, methane concentrations. The work program has three complementary strands. (1) Pure culture and sedimentary microcosm experiments providing an approximation to natural conditions. (2) Calibration of BHP signatures in natural marine settings (e.g. cold seeps, mud volcanoes, pockmarks) against measured methane gradients. (3) Application of this novel approach to the marine sedimentary record to approximate methane fluxes in the past, explore the age and bathymetric limits of this novel molecular proxy, and identify and potentially 14C date palaeo-pockmarks structures. Crucial to the success is also the refinement of the analytical protocols to improve both accuracy and sensitivity, using a more sensitive analytical instrument (triple-quadrupole mass spectrometer).

1 496 392 €

Start date: 2010-11-01, End date: 2016-04-30

"Chemical elements are the building blocks of life. The major elements, C, H. O, N, P, S are easily recognised as essential nutrients, but their use by life relies on metalloproteins. The identity of the metal centres of these metalloproteins and even the broader palette of trace elements fundamental to life are remarkably poorly known. Whole genomes remain opaque to decoding of this bioinorganic dimension, and optimal trace element concentrations for physiological function. Defining the elemental requirements for maximum growth rate of photosynthesising phytoplankton in the ocean, is critical to understanding Earth's climate. Although microscopic in stature, phytoplankton exert a gigantic influence on the biological pumping of carbon from the atmosphere to the deep ocean. Yet their metal requirements are poorly constrained, being inferred from cellular quotas and "nutrient-like" ocean metal distributions, susceptible to ambiguity between mistaken cellular uptake and use. APPELS will undertake a two-pronged approach to define the modern marine metallome/metalloproteome. I will explore the expanse of the periodic table for novel required elements by growing phytoplankton, representative of the broadest chemotypes, in manipulated media, to delineate optimal conditions for growth whereby any limitation at lowered concentrations implies use. The second prong uses cutting-edge techniques that unite methods from proteomics with geochemical mass-spectrometry to allow both metals and their associated proteins to be examined comprehensively. APPELS will transform our understanding of the essential elements in the ocean and how the biological pump of carbon is geared to ocean chemistry in an evolving world. More broadly, APPELS will provide a step change in documented protein-metal binding centres, with implications for discovery of novel biochemical pathways, and optimal nutrition."

2 000 000 €

Start date: 2016-06-01, End date: 2021-05-31

Knowledge is an anthropological constant that is indissociable from the birth and interactions of human societies, but is at best a secondary concern for scholars of international relations and globalization. Contemporary global studies are thus unable to account for the co-constitution of knowledge and politics at a macro-scale, and remain especially blind to the historical patterns of epistemic development that operate at the level of the species as a whole and have shaped its global political history in specific, path-dependent ways up to now. ARTEFACT is the first project to pursue a knowledge-centered investigation of global politics. It is uniquely grounded in an anthropological approach that treats globalization and human knowledges beyond their modern manifestations, from the longue-durée perspective of our species’ social history. 'The global as artefact' is more than a metaphor. It reflects the premise that human collectives 'make' the political world not merely through ideas, language, or norms, but primordially through the material infrastructures, solutions, objects, practices, and skills they develop in response to evolving structural challenges. ARTEFACT takes agriculture as an exemplary and especially timely case-study to illuminate the entangled global histories of knowledge and politics, analyzing and comparing four increasingly inclusive 'global political systems' of the Ancient, Medieval, Modern, and Contemporary eras and their associated agrarian socio-epistemic revolutions. ARTEFACT ultimately aims to 1) develop an original theory of the global, 2) launch Global Knowledge Studies as a new cross-disciplinary domain of systematic empirical and theoretical study, and 3) push the respective boundaries of the anthropology of knowledge, global history, and international theory beyond the state-of-the-art and toward a holistic understanding that can illuminate how past trends of socio-epistemic evolution might shape future paths of global life.

1 428 165 €

Start date: 2017-09-01, End date: 2022-08-31

The Arctic Ocean is a vast expanse of sea ice. Most of it is snow covered as are large continental regions for about half of the year. However, Global Change is arguably greatest in the Arctic, where temperatures have risen more than anywhere else in the last few decades. New record lows occurred in snow extent in June 2012 and sea ice extent in September 2012. Many observations show that widespread and sustained change is occurring in the Arctic driving this unique environmental system into a new state. This project focuses on the biogeochemical links between sea ice and snow and the composition and chemistry of the troposphere (the lowest ~10km of the atmosphere). This is an important topic because the concentrations of greenhouse gases and aerosol particles, which scatter sunlight directly and influence cloud properties, play key roles for our climate. Additionally, changes in the composition of the troposphere also affect the so-called oxidation capacity, the capability of the atmosphere to cleanse itself from pollutants. This project aims to deliver a step change improvement in our quantitative understanding of chemical exchanges between ocean, sea ice, snow and the atmosphere in polar regions, especially the Arctic and of Arctic tropospheric chemistry. Answering these fundamental questions is essential to predict future change in the Arctic and globally. To this end a unique sea ice chamber will be constructed in the laboratory and used to quantify exchange processes in sea ice. Furthermore a hierarchy of numerical models will be used, operating at different spatial and temporal scales and degree of process description from a very detailed 1D to a global Earth System model. This will allow a breakthrough in our understanding of the importance of the changes for the composition and oxidation capacity of the atmosphere and climate and will allow us to calculate adjusted Greenhouse Warming Potentials that include these processes.

1 192 911 €

Start date: 2014-05-01, End date: 2016-09-30

The proposed research entails an ethnographic study of two contemporary cases of post-conflict reconciliation: one, the Bosnian case, where international intervention ended conflict in a stalemate and went on to instigate a decade-long process of transition; and the other, the Spanish case, where a nationally-contrived pact of silence introduced an overnight transition after Franco's death a pact now being broken nearly seventy years after the country's civil war concluded. Both societies witnessed massive violations of international humanitarian law. Both societies are presently exhuming, identifying and re-burying their dead. But their trajectories of transitional justice could not have been more different. This project will investigate how Law shapes cultural memories of wartime atrocity in these contrasting scenarios. How do criminal prosecutions, constitutional reforms, and international rights mechanisms, provide or obfuscate the scales into which histories of violent conflict are framed? Does the systematic re-structuring of legislative and judicial infrastructure stifle recognition of past abuses or does it create the conditions through which such pasts can be confronted? How does Law shape or inflect the cultural politics of memory and memorialisation? And most importantly, how should legal activity be weighted, prioritised and sequenced with other, extra-legal components of peace-building initiatives? The ultimate goal of this project will be to mobilise the findings from the two field-sites to suggest a more nuanced assessment of Law s place in transitional justice. Arguing that disparate historical, cultural and legal contexts require equally distinct approaches towards social healing, the research aims to produce a Post-Conflict Action Framework an architecture of questions and concerns, which, once answered, would point towards context-specific designs for transitional justice programmes in the future.

1 420 000 €

Start date: 2009-09-01, End date: 2013-08-31

Can benefit-sharing address the equity deficit within the green economy? This project aims to investigate benefit-sharing as an under-theorised and little-implemented regulatory approach to the equity concerns (disregard for the special circumstances of developing countries and of indigenous peoples and local communities) in transitioning to the green economy. Although benefit-sharing is increasingly deployed in a variety of international environmental agreements and also in human rights and corporate accountability instruments, no comprehensive account exists of its conceptual and practical relevance to equitably address global environmental challenges. This project will be the first systematic evaluation of the conceptualisations and operationalisations of benefit-sharing as a tool for equitable change through the allocation among different stakeholders of economic and also socio-cultural and environmental advantages arising from natural resource use. The project will combine a comparative study of international law with empirical legal research, and include an inter-disciplinary study integrating political sociology in a legal enquiry on the role of “biocultural community protocols” that articulate and implement benefit-sharing at the intersection of international, transnational, national and indigenous communities’ customary law (global environmental law). The project aims to: 1. develop a comprehensive understanding of benefit-sharing in international law; 2. clarify whether and how benefit-sharing supports equity and the protection of human rights across key sectors of international environmental regulation (biodiversity, climate change, oceans, food and agriculture) that are seen as inter-related in the transition to the green economy; 3. understand the development of benefit-sharing in the context of global environmental law; and 4. clarify the role of transnational legal advisors (NGOs and bilateral cooperation partners) in the green economy.

1 481 708 €

Start date: 2013-11-01, End date: 2018-10-31

This research project investigates the dynamics of private and public property in contemporary biomedical research. It will develop an analytical framework combining insights from science and technology studies, economic sociology, and legal and political philosophy, and pursues a social scientific investigation of the evolution of intellectual property rights in three fields of bioscientific research: 1) the use of transgenic research mice; 2) the legal status of totipotent and pluripotent stem cell lines; and 3) modes of collaboration for research and development on neglected diseases. These three domains, and their attendant modes of appropriation, will be compared across three general research themes: a) the production of public scientific goods; b) categories of appropriation; and c) the moral economy of research. The project rests on close observation of research practices in these three domains. The BioProperty research programme will track the trajectories of property rights and property objects in each of the three fields of biomedical research.

887 602 €

Start date: 2011-03-01, End date: 2014-12-31

Contemporary organizations face three interrelated, but analytically distinguishable, challenges. First, they should be alert to mistakes that could be catastrophic. Second, they need to allocate attention, especially to correct past mistakes and to make accurate predictions about future developments. Third, they should be innovative, able to stand out from existing categories while being recognized as outstanding. This project investigates these cognitive challenges with the aim of developing a comprehensive sociological approach to study the social properties of cognition. Research on error detection, attention allocation, and recognizant innovation will be conducted in three distinct settings strategically chosen so the scale and complexity of the performance challenges increases across the cases. The research question that cuts across the socio-cognitive challenges asks whether and how diversity contributes to performance. 1) We first test whether social context, understood at the most basic level as the composition of a small collectivity, affects the cognitive activity of pricing. To do so, I use experimental market methods to test whether ethnic and gender diversity deflate price bubbles by disrupting herding behaviour. 2) The second study tests how the social structure of attention affects valuation. The activities involve error correction and accuracy of prediction in estimates by securities analysts; the method is two-mode network analysis; and the timing, intensity, and diversity of attention networks are the effects to be tested. 3) Whereas my first two tests examine relations among competitors, my third examines relations within and across collaborative teams. In studying the network properties of creativity, the challenge is recognizant innovation, the activity involves recording sessions in the field of music, the method is cultural network analysis, and the effects to be tested are the combined effects of stylistic diversity and social structure.

2 492 033 €

Start date: 2016-09-01, End date: 2021-08-31

"Ice-core records show that glacials had lower atmospheric pCO2 and cooler temperatures than today and that the last deglaciation was punctuated by large, abrupt millennial-scale climate events. Explaining the mechanism controlling these oscillations remains an outstanding puzzle. The ocean is a key player, and the Atlantic is particularly dynamic as it transports heat, carbon and nutrients across the equator. This project proposes to consolidate my research through a focused study of present and past ocean chemistry in the Equatorial Atlantic and to assess the impact of ocean chemistry on fragile deep-sea ecosystems. Despite decades of research there are distinct gaps in our knowledge of the history of the deep and intermediate ocean. Major hurdles include access to suitable archives, development of geochemical proxies and analyses that are sufficiently precise to test climate hypotheses. Through a combination of ship board field work, modern calibrations and cutting-edge geochemical analyses this project will produce samples and data that address each of these gaps. A particular focus will be on using the skeletons of deep-sea corals. Research using deep-sea corals as climate archives, and indeed research into their habitats, environmental controls and potential threats to their survival are still fields in their infancy. The expense and logistics of working in the deep ocean, the complexity of the ecosystem and the biogeochemistry of the coral skeletons have all proved to be significant challenges. The potential payoffs of high-resolution, dateable archives, however, make the effort worthwhile. There have been no studies that attempt to match up co-located deep-sea coral, seawater and sediment samples in a single program, so this would be the first directed study of its type, and as such promises to provide a substantial step in quantifying the fluxes and transport of mass, heat and nutrients across the equator in the past."

1 998 833 €

Start date: 2011-10-01, End date: 2017-09-30

"What kinds of self does it take to make a revolution? And how does revolutionary politics, understood as a project of personal as much as political transformation, articulate with other processes of self-making, such as religious practices? Comparative Anthropologies of Revolutionary Politics (CARP) seeks fundamentally to recast our understanding of revolutions, using their relationship to religious practices in diverse social and cultural settings as a lens through which to reveal revolutions’ varied capacities for self-making. Developing a comparative matrix of revolutionary settings in the Middle East, Latin America and elsewhere, CARP’s core objective is to investigate the differing permutations and dynamics of revolutionary ‘anthropologies’ in the original theological sense of the term, i.e. charting revolutionary politics in relation to varying conceptions of what it is to be human, and of how the horizons of people’s lives are to be understood in relation to divine orders of different kinds, in order to reveal how revolutions come to define what persons may be, deliberately setting the social, political, cultural and ultimately ontological coordinates within which people are made who they are. Bringing close ethnographic investigation to bear on conceptions of revolution, statecraft, and subjectivity in political theory, CARP will produce comprehensive political ethnographies of nine major case-studies, comparing systematically the relationship between revolution and religion in a selection of countries in the Middle East and Latin America. Four smaller-scale case-studies from Europe and Asia will add complementary dimensions to this comparative matrix. Providing much-needed empirical materials and analytical insight into the dynamic comingling of political and religious forms in the making of revolutionary selves, CARP’s ultimate ambition is to launch the comparative study of revolutionary politics as a major new departure for anthropological research."

1 854 472 €

Start date: 2014-06-01, End date: 2019-05-31

The way in which normative principles (“norms”) matter in world politics is now a key area of international relations research. Yet we have limited understanding of why some norms emerge and gain traction globally whereas others do not. The politics of loss and damage related to climate change offers a paradigm case for studying the emergence of - and contestation over - norms, specifically justice norms. The parties to the UN Framework Convention on Climate Change (UNFCCC) have recently acknowledged that there is an urgent need to address the inevitable, irreversible consequences of climate change. Yet within this highly contested policy area - which includes work on disaster risk reduction; non-economic losses (e.g. loss of sovereignty); finance and climate-related migration - there is little consensus about what loss and damage policy means or what it requires of the global community, of states and of the (current and future) victims of climate change. Relying on an interdisciplinary theoretical approach and an ethnographic methodology that traverses scales of governance, my project - The Politics of Climate Change Loss and Damage (CCLAD) - will elucidate the conditions under which a norm is likely to become hegemonic, influential, contested or reversed by introducing a new understanding of the fluid nature of norm-content. I argue that norms are partly constituted through the practices of policy-making and implementation at the international and national level. The research will examine the micro-politics of the international negotiations and implementation of loss and damage policy and also involves cross-national comparative research on domestic loss and damage policy practices. Bringing these two streams of work together will allow me to show how and why policy practices shape the evolution of climate justice norms. CCLAD will also make an important methodological contribution through the development of political ethnography and “practice-tracing” methods.

1 471 530 €

Start date: 2018-05-01, End date: 2023-04-30

This project will investigate, through three case studies, the relationship between technologies and practices of environmental sensing and citizen engagement. Wireless sensors, which are an increasing part of digital communication infrastructures, are commonly deployed for environmental monitoring within scientific study. Practices of monitoring and sensing environments have migrated to a number of everyday participatory applications, where users of smart phones and networked devices are able to engage with similar modes of environmental observation and data collection. Such “citizen sensing” projects intend to democratize the collection and use of environmental sensor data in order to facilitate expanded citizen engagement in environmental issues. But how effective are these practices of citizen sensing in not just providing “crowd-sourced” data sets, but also in giving rise to new modes of environmental awareness and practice? Through intensive fieldwork, study and use of sensing applications, the case studies will set out to contextualize, question and expand upon the understandings and possibilities of democratized environmental action through citizen sensing practices. The first case study, “Wild Sensing,” will focus on the use of sensors to map and track flora and fauna activity and habitats. The second case study, “Pollution Sensing,” will concentrate on the increasing use of sensors to detect environmental disturbance, including air and water pollution. The third case study will investigate “Urban Sensing,” and will focus on urban sustainability or “smart city” projects that implement sensor technologies to realize more efficient or environmentally sound urban processes.

1 500 000 €

Start date: 2013-01-01, End date: 2017-12-31

The ubiquity of arsenic resistant genes across all of life’s variety suggests a close intimacy between arsenic biogeochemistry and evolution, over geological time scales. However, the behaviour of arsenic in past environments where life originated and its impact on our evolution is essentially unknown. Arsenic is of particular importance because of its toxic properties, prevalence in tight association with ubiquitous iron and sulfide minerals and as a major component of sulfide-rich waters, all common features of Precambrian oceans. Arsenic obstructs the synthesis of the building blocks of life, exhibiting both chronic and acute toxicity at very low concentrations. These properties make arsenic an agent capable of exerting strong selective pressure on the distribution, success and diversity of life. This is exemplified by when the release of arsenic into groundwater following rock-weathering processes results in widespread poisoning. Using the state of the art stable isotopes tools, coupled to biomass production, bacterial iron, arsenic and sulfur cycling under ancient oceanic conditions, this project will open a new discussion on the much debated relationship between ocean chemistry and evolution, by introducing a new arsenic framework. This will be achieved under three majors themes: 1) Does there exist a biogeochemical connection between arsenic and the timing and transition from the iron-rich to the hypothesized sulfide-rich oceans that are linked to the rise of atmospheric oxygen? 2) Does arsenic and sulfide show concomitant cyclicity during the Precambrian? 3) Could arsenic thus serve as a proxy for the calibration of key transitional steps in the timing of biological innovation?

1 486 374 €

Start date: 2013-09-01, End date: 2018-08-31

"Global climate change induced by anthropogenic emissions of CO2 is currently a major issue facing humanity, but uncertainties in the magnitude and rate of climate change remain, and deterministic predictions are beyond our capacity. In this context, the study of how the geochemical carbon cycle established a relatively narrow band of variability in atmospheric CO2 concentrations over the last 400 ka is of great interest. However, large uncertainties in both weathering and volcanic CO2 fluxes prevent a truly quantitative assessment of this critical cycle. Measuring the global volcanic CO2 flux, GVFCO2, would allow us to better understand the likely impact large eruptions have had in Earth’s history, and constrain the natural vs. anthropogenic CO2 flux. We propose a truly innovative project to address head on the problem of determining GVFCO2. We will create new, compact instruments, utilising cutting-edge laser technologies, which will allow us to measure volcanic CO2, H2O, SO2 and HCl fluxes from aircraft. By flying below and through the volcanic plumes created by ~50 active volcanoes (~10% of all active volcanoes) of the Banda-Sunda arc in Indonesia, the majority of which have never been measured before, we will dramatically increase our understanding of GVFCO2 and geochemical cycles for all these species. Measuring the volcanic emissions from an entire subduction arc is an unprecedented experiment, providing insight into the slab and mantle heterogeneity and volatile mass balance. Perhaps the most important breakthrough that we will pursue will be the determination of the 37Cl/35Cl ratio from HCl emitted from each volcano. This ratio reflects the mantle/slab source proportion, and allows the input rate of volatiles to the mantle to be measured. The application of innovative new technology we propose here will produce ground-breaking insights into volcanology, isotope and gas geochemistry, volatile cycles, subduction and climate change."

1 721 000 €

Start date: 2012-01-01, End date: 2017-12-31

"This project addresses a fundamental problem – the size of the cosmic dust input to the earth’s atmosphere. Zodiacal cloud observations and spaceborne dust detection indicate a daily input of 100 – 300 tonnes, in agreement with the accumulation rates of cosmic elements (e.g. Ir, Pt) in polar ice cores and deep-sea sediments. In contrast, measurements in the middle atmosphere – by radar, lidar, high-flying aircraft and satellite remote sensing – indicate that the input is only 5 - 50 tonnes. The aim of CODITA is to resolve this huge discrepancy. There are two reasons why this matters. First, if the upper range of estimates is correct, then vertical transport in the middle atmosphere must be considerably faster than generally believed; whereas if the lower range is correct, then our understanding of dust evolution in the solar system, and transport from the middle atmosphere to the surface, will need substantial revision. Second, cosmic dust particles enter the atmosphere at high speeds and in most cases completely ablate. The resulting metals injected into the atmosphere are involved in a diverse range of phenomena, including: formation of layers of metal atoms and ions; nucleation of noctilucent clouds; impacts on stratospheric aerosols and O3 chemistry (which need to be evaluated against the background of a cooling stratosphere and geo-engineering plans to increase sulphate aerosol); and fertilization of the ocean with bio-available Fe, which has potential climate feedbacks. CODITA will use laboratory studies to target poorly understood aspects of this problem, such as the nature of the ablation process itself, the formation of meteoric smoke particles, and their role in ice nucleation and the freezing of polar stratospheric clouds. The results will be incorporated into a chemistry-climate model of the whole atmosphere, so that it will be possible, for the first time, to model the effects of cosmic dust self-consistently from the thermosphere to the surface."

2 484 369 €

Start date: 2012-04-01, End date: 2017-03-31

The core-mantle interface is the central cog in the Earth's titanic heat engine. As the boundary between the two major convecting parts of the Earth system (the solid silicate mantle and the liquid iron outer core) the properties of this region have a profound influence on the thermochemical and dynamic evolution of the entire planet, including tectonic phenomena at the surface. Evidence from seismology shows that D" (the lowermost few hundred kilometres of the mantle) is strongly heterogeneous in temperature, chemistry, structure and dynamics; this may dominate the long term evolution of the Earth's magnetic field and the morphology of mantle convection and chemical stratification, for example. Mapping and characterising this heterogeneity requires a detailed knowledge of the properties of the constituents and dynamics of D"; this is achievable by resolving its seismic anisotropy. The observation of anisotropy in the shallow lithosphere was an important piece of evidence for the theory of plate tectonics; now such a breakthrough is possible for the analogous deep boundary. We are at a critical juncture where developments in modelling strain in the mantle, petrofabrics and seismic wave propagation can be combined to produce a new generation of integrated models of D", embodying more complete information than any currently available. I propose a groundbreaking project to build such multidisciplinary models and to produce the first complete image of lowermost mantle anisotropy using the best available global, high resolution seismic dataset. The comparison of the models with these data is the key to making a fundamental improvement in our understanding of the thermodynamics and composition of the core-mantle interface, and illuminating its role in the wider Earth system.

1 639 615 €

Start date: 2009-09-01, End date: 2015-08-31

Recent years have seen renewed interest in the political economy of punishment, yet almost no attention has been given to the factors that translate socio-political arrangements into penal practices or the specific nature of imprisonment in different political-economic systems. Based on research in England & Wales and one Nordic nation, the project goals are to expose the dynamics of the penal state and the nature of penality in countries that are considered ‘exclusionary’ and ‘inclusionary’ respectively in their socio-economic and penal practices. These goals will be achieved through four comparative sub-projects: first, a study of penal policymaking and the ‘penal field’ (the players and processes that shape penal policy and practice); second, an exploration of the texture of imprisonment for women and sex offenders, groups presumed to experience inclusionary and exclusionary penal practices in distinctive ways; third, a study of how these prisoners experience entry into and exit from the system; fourth, a study of the ‘deep end’ imprisonment in both countries. A central aim is to interrogate widespread assumptions about the relative mildness/severity of penal practices in inclusionary and exclusionary nations. The research will employ an emerging framework that conceptualises the prison experience through notions of ‘depth’, ‘weight’, ‘tightness’ and ‘breadth’. It will foreground the roles of shame and guilt in shaping prisoners’ orientations, concepts that feature in theories of offending and reintegration, but are absent from the sociology of imprisonment. Through the concept of ‘penal consciousness’, the project will also explore the interaction between the punitive intentions of the state and prisoners’ perceptions of the purposes and legitimacy of their punishment. The research will be groundbreaking in several ways, reshaping the field of comparative penology, and linking macro issues of the penal state with the lived realities of the prison landings.

1 964 948 €

Start date: 2015-09-01, End date: 2020-08-31

Over the next five years an unprecedented number of initiatives will coalesce, contributing to an extension of the reach of the Internet to the world’s most remote regions. While previous efforts to expand Internet access have focused on urban areas, current initiatives are leveraging new technologies from drones to satellites to provide affordable access to the worlds poorest, many of whom are in Africa and live in regions where the state is weak and there is protracted violent conflict. Current debates have largely focused on technical issues of improving access, or assumed ways that technology will help ‘liberate’ populations or improve governance. This project focuses on a key puzzle that is often overlooked: How does increased access to social media affect the balance between peace-building efforts and attempts perpetuate violence in conflict-affected communities? With a focus on Africa (and particularly on religious and political violence in Eastern Africa), this project will investigate the relationship between social media and conflict through three research questions at the macro, meso and micro level: how are social media altering the transnational dimensions of conflict and peacebuilding? How are public authorities reacting to, and appropriating, social media to either encourage violence or promote peace? And in what ways are social media changing the way people experience, participate in, or respond to violent conflict? It will examine these questions in the context of dangerous speech online; the exit and entry of individuals away from, and into, conflict; the tactics and strategies actors adopt to shape the Internet; and how governance actors are leveraging social media in conflict-affected communities.

1 499 450 €

Start date: 2017-08-01, End date: 2022-07-31

Vertebrates contain hundreds of different cell types which maintain phenotypic identity by a combination of epigenetic programming and genomic regulation. Systems biology approaches are now used in a number of laboratories to determine how transcription factors and chromatin marks pattern the human genome. Despite high conservation of the cellular and molecular function of many mammalian transcription factors, our recent experiments in matched mouse and human tissues indicates that most transcription factor binding events to DNA are very poorly conserved. A hypothesis that could account for this apparent divergence is that the larger regional pattern of transcription factor binding may be conserved. To test this, (1) we are characterizing the global transcriptional profile, chromatin state, and complete genomic occupancy of a set of tissue-specific transcription factors in hepatocytes of strategically chosen mammals; (2) to further identify the precise mechanistic contribution of cis and trans effects, we are comparing transcription factor binding at homologous regions of human and mouse DNA in a mouse line that carries human chromosome 21. Together, these projects will provide insight into the general principles of how transcriptional networks are evolutionarily conserved to regulate cell fate specification and function using a clinically important cell type as a model.

960 000 €

Start date: 2008-10-01, End date: 2013-09-30

The carbon cycle is a vital aspect of our planet’s well-being. However, there are fundamental aspects of it that we do not understand, without which we cannot accurately quantify CO2 budgets. How, and at what rate, does the carbon cycle respond to, and recover from, events of rapid and extreme global warming or cooling? What process has maintained the climate within a habitable range for billions of years? Silicate weathering is Earth’s main long-term CO2 removal process, and therefore a dominant climate control mechanism. Critically, we do not understand the controls on silicate weathering, or its full effects on atmospheric pCO2 and climate. The goal of this project is to determine and quantify how weathering responded during past periods of rapid climate change, using an innovative combination of novel stable isotope techniques, laboratory experiments and advanced carbon cycle modelling. This will determine the behaviour of a key, relatively unknown, factor in the carbon cycle. This project comprises three, highly novel, interlinked strands: 1) Examination of the palaeo-weathering record through recent glacial timescales using cave speleothems as a climate archive, 2) Determination of palaeo-weathering records through older, Cenozoic, rapid shifts in climate, using marine carbonates and clays as an archive, and 3) Advanced models to enhance our understanding of this record. This project will radically improve our quantitative knowledge of the controls over the carbon cycle. This is critical because 1) it is possible that weathering is the process that has maintained Phanerozoic climate in the relatively narrow bands required for life; 2) it is impossible to decipher the causes and consequences of long-term climate variations through Earth’s history without accurate weathering data; 3) detailed comprehension of rapid climate variations will enable more accurate predictions of future CO2 drawdown.

2 000 000 €

Start date: 2017-02-01, End date: 2022-01-31

Political science conceptualises state-market relations as balancing acts between the public sphere (the state or government) and the private sphere (the market, dominated by large corporate bodies). The expansion of the global market has been led by the rise of large and highly mobile multinational firms. Since many of these companies command turnover comparable to the GDP of middle size states, globalisation is often seen as a global shift of power from states to markets, where corporate power stems from centralisation of resources, capital and structural influence over politics and society. Yet over the past three decades, large firms have been strategically dividing themselves into hundreds and even thousands of multi-unit, multi-layered and multi-jurisdictional cells. Typically constructed to maximise flexibility and opportunity, such de-centring of the global firm over time has increased, not decreased, the power of the corporation in world politics, society and economy. Such practices amount to a new dimension of corporate power, arbitrage power, which is the main concept underpinning this project. Arbitrage power can be defined as the capacity of economic agents to capitalise on the gaps in the institutional and legal framework of the global economy. Traditional approaches to power analysis which conventionally prioritise individual agents or clusters of interests, are of limited help when engaging with the complex ecology of a de-centred firm. CORPLINK has two aims: a) to develop a theoretical framework to study the processes of ‘arbitrage power’ as a distinct facet of economic power; b) to develop a novel transferable methodology for the investigation of corporate arbitrage power, CPL maps (Corporate Processes and Linkages maps). Specifically, the project innovates a new tool for the study of the firm as a political actor that navigates through complex networks and modalities of the global system of governance.

1 739 387 €

Start date: 2016-12-01, End date: 2020-11-30

Cells must integrate output from multiple genetic circuits in order to correctly control cellular processes. Despite much work characterizing regulation in these circuits, how circuits interact to control global cellular programs remains unclear. This is particularly true given that recent research at the single cell level has revealed that genetic circuits often generate variable or stochastic regulation dynamics. In this proposal we will use a multi-disciplinary approach, combining modelling and time-lapse microscopy, to investigate how cells can robustly integrate signals from multiple dynamic genetic circuits. In particular we will answer the following questions: 1) What types of dynamic signal encoding strategies are available for the cell? 2) What are the benefits of dynamic gene activation, whether stochastic or oscillatory, to the cell? 3) How do cells couple and integrate output from diverse gene modules despite the noise and variability observed in gene circuit dynamics? We will study these questions using 2 key model systems. In Aim 1, we will examine stochastic pulse regulation dynamics and coupling between alternative sigma factors in B. subtilis. Our preliminary data has revealed that multiple B. subtilis sigma factors stochastically pulse under stress. We will look for evidence of any coupling or interactions between these stochastic pulse circuits. This system will serve as a model for how a cell uses stochastic pulsing to control diverse cellular processes. In Aim 2, we will examine coupling between a deterministic oscillator, the circadian clock, and multiple other key pathways in Cyanobacteria. We will examine how the cell can dynamically couple multiple cellular processes using an oscillating signal. This work will provide an excellent base for Aim 3, in which we will use synthetic biology approaches to develop ‘bottom up’ tests of generation of novel dynamic coupling strategies.

1 499 571 €

Start date: 2014-02-01, End date: 2019-01-31

Crustal magmatism is periodic on a very wide range of timescales from pulses of continental crustal growth, through formation of granite batholiths, to eruptions from individual volcanic centres. The cause of this periodicity is not understood. I aim to address this long-standing geological problem through a combination of experiments, petrological methods and numerical models via a novel proposal that periodicity arises because of the highly non-linear ( critical ) behaviour of magma crystallinity with temperature in a series of linked crustal magma reservoirs. The ultimate objective is to answer five fundamental questions: " Why is crustal magmatism episodic? " How are large batholiths formed of rather similar magmas over long periods of time? " How do large bodies of eruptible magma develop that can lead to huge, caldera-forming eruptions? " What controls the chemistry of crustal magmas? Why are some compositions over-represented relative to others? " What is the thermal structure beneath volcanic arcs and how does it evolve with time? The project will address these questions through case studies of three contrasted active volcanoes: Nevado de Toluca, Mexico; Soufriere St Vincent, Lesser Antilles; and Mount Pinatubo, Philippines. For each volcano I will use experimental petrology to constrain the phase relations of the most recently erupted magma as a function of pressure, temperature, volatile content and oxygen fugacity in the shallow, sub-volcanic storage region. I will also carry out high-pressure phase equilibria on coeval Mg-rich basaltic rocks from each area with the aim of constraining the lower crustal conditions under which the shallow magmas were generated and use diffusion chronometry to constrain the frequency of magmatic pulses in the sub-volcanic reservoirs. The project will result in a quantum leap forwards in how experimental and observational petrology can be used to understand magmatic behaviour beneath hazardous volcanoes

2 959 518 €

Start date: 2010-04-01, End date: 2015-03-31

The profound trauma associated with rape and sexual violence in conflict has been extensively explored within existing scholarship. The fact that many survivors exhibit remarkable post-trauma resilience, however, remains critically under-investigated. CSRS will address this fundamental gap by undertaking a paradigm-shifting empirical study of the underlying conditions for resilience. It will then use this data to pioneer a new, survivor-centred model of transitional justice – the process of redressing the legacy of massive human rights abuses. Using the three comparative case studies of Bosnia-Hercegovina (BiH), the Democratic Republic of Congo (DRC) and Colombia, and adopting a social-ecological approach that emphasizes the interactions between individuals and their environments, CSRS consists of two inter-linked parts. The first part will involve extensive fieldwork, using a combination of quantitative and qualitative research methods, to generate a rich cross-cultural dataset that identifies and explains the key micro, meso and macro factors that foster resilience in survivors of war rape and sexual violence. The second part of CSRS will use this dataset to build an innovative, bottom-up model of transitional justice that prioritizes the long-term needs of survivors, reflecting the project’s hypothesis that a positive correlation exists between fulfilment of needs and resilience. This model will be developed with the input of survivors in BiH, the DRC and Colombia and in consultation with transitional justice scholars and practitioners. CSRS aims to transform transitional justice theory and practice. The project outputs will therefore include both academic publications and policy reports to communicate the model to the governments of the case study countries, the United Nations and a wider international audience with the overall aim of making empowerment and resilience part of a new transitional justice agenda.

1 790 580 €

Start date: 2017-09-01, End date: 2022-08-31

A major problem in understanding complex nonlinear geophysical systems is to determine which processes drive which other processes, so what the causal relations are. Several methods to infer nonlinear causal relations exist, but often lead to different answers, often perform hypothesis testing on causality, need long stationary time series, can be misleading if an unknown process drives the processes under study, or, if a numerical model is used, reflect model causality instead of real-world causality. Furthermore methods that use the governing evolution equations directly lead to intractable high-dimensional integrals. In this proposal I will tackle these problems by firstly embedding causality into a Bayesian framework, moving from testing causality to estimating causality strength and its uncertainty in a systematic way. Knowledge from several causality methods can be combined, new knowledge can be brought in systematically, and time series can be short. Furthermore, new knowledge can be incorporated into the existing knowledge basis, and several methods can be combined in a consistent manner. Secondly, a new formulation to infer causal strength exploring evolution equations that avoids high-dimensional integrals will be explored. Thirdly, numerical models are combined with observations by exploring fully nonlinear data assimilation to study real-world causality. I will test the new techniques on simple models and then apply them to a high-resolution model of the ocean area around South Africa where the Southern Ocean, the Indian Ocean, and the Atlantic Ocean meet. This area plays a crucial role in the global circulation of heat and salt by bringing warm and salty Indian Ocean water into the Atlantic in a highly turbulent manner. The techniques allow to infer what sets this interocean transport, the turbulent local dynamics or the global climate-related dynamics, crucial for understanding the functioning of the ocean in the climate system.

2 597 754 €

Start date: 2016-09-01, End date: 2021-08-31

This project seeks to recover the processes by which religious beliefs and identities were defined through interreligious interaction and debate in the religious culture of a broader social base in the eastern Mediterranean (6-8th centuries AD) through examination of a neglected, unconventional corpus of medieval Greek, Syriac and Arabic literature of debate and disputation (consisting of collections of questions and answers, dialogues among others), treating authors such as Ps. Kaisarios, Anastasios of Sinai, and Ps. Athanasios. These sources help us to understand the kinds of perplexities that were being raised in Christian communities of the eastern Mediterranean as they negotiated a lively and contentious religious and social landscape, and they highlight the multifarious issues which Christian leaders had to be prepared to deal with in their pastoral, pedagogical, and apologetic work. At the same time these collections must be seen as an attempt by Christian authors to work out how Christianity was to define its position with regard to other religions (Hellenism, Judaism and Islam) in a period still characterized by considerable fluidity and change. As well as writing those doubts, challenges, objections, concerns, issues and anxieties back into the religious history of the eastern Mediterranean, when completed this full-length study of these texts will provide scholars not only with a detailed knowledge of the ways in which religious belief, practice and communities were defined in contrast to other religious systems, and a fuller sense of the religious, social and intellectual history of the eastern Mediterranean but also with a nuanced picture of their self-definition, one which will be more sensitive to the processes that led to its formation.

1 483 119 €

Start date: 2011-01-01, End date: 2016-12-31

Extensive and ongoing tropical deforestation and degradation have important environmental impacts. Smoke aerosol from deforestation fires degrades air quality, but the effects are poorly quantified. Deforestation alters rainfall through changes in the land surface and through changes to atmospheric aerosol. The magnitude and the sign of the rainfall response is not clear, because of poor process-level understanding and because previous attempts have studied land surface and aerosol responses separately. The impacts of deforestation on atmospheric composition and climate cause a complex set of biosphere interactions resulting in potential Earth system feedbacks. These feedbacks have not yet been quantified and so their importance is not known. The full impact of deforestation on air quality, climate and the Earth System may have been underestimated because there have been no integrated studies of the combined interactions and feedbacks between deforestation and the Earth system. DECAF is the first integrated study of the combined interactions and feedbacks between tropical deforestation, fire, atmospheric composition and climate. To address this important challenge, DECAF will exploit new information from in-situ and satellite observations in combination with state-of-the-art numerical models. DECAF will deliver improved process-level knowledge of the impacts of deforestation on atmospheric composition and climate and a step change in our understanding of the interactions and feedbacks between deforestation, atmospheric composition and climate. New understanding will inform the development of climate and Earth System Models and will facilitate new climate and Earth system assessments.

1 965 623 €

Start date: 2018-03-01, End date: 2023-02-28

DenCity offers a new approach for understanding density and its relationship to the city. Density is a defining feature of the city and urban life. Across the world, density is now at the centre of policy and planning agendas to build cities that are environmentally, economically, socially and politically ‘sustainable’. While there is a lively tradition of research on density in the city, we lack an understanding of the different ways in which high densities are lived and perceived by residents. Existing research provides rich resources for how we might define and represent density, how we might arrive at optimum numbers of people in a given area, and how capitalism builds or reduces densities within and between places globally. However, we lack an understanding of how high density – what I call intensity – is understood and experienced by different urban inhabitants, and the implications for how we understand the contemporary city. Developing a ‘density assemblage’ approach, I propose to examine the ways in which residents differently know and relate to intensity, including how it comes to matter, for good or ill. I do so by examining different cases of intensity in the Asian city, from travel and transport hubs, and slums to rooftops. While the 20th century witnessed a general global decrease of urban density in favour of urban sprawl, many Asian cities continue to densify. Asia is the densest and most urbanized part of the planet, and the trend is predicted to continue. I will examine some of the highest densities in the world, including in Hong Kong, Mumbai, Manila, Dhaka, and Tokyo. The different ways in which intensity becomes known and comes to matter for residents will be a vital challenge for understanding life in the urban 21st century, and for how we understand the city.

1 344 681 €

Start date: 2018-09-01, End date: 2022-08-31

"The spatial organization of the genome inside the cell nucleus is tissue-specific and has been linked to several nuclear processes including gene activation, gene silencing, genomic imprinting, gene co-regulation, genome maintenance, DNA replication, DNA repair, chromosomal translocations and X chromosome inactivation. In fact, just about any nuclear/genome function has a spatial component that has been implicated in its control. We know surprisingly little about chromosome conformation and spatial organization or how they are established. The extent to which they are a cause or consequence of genome functions are current topics of considerable debate, however emerging data from my group and many other groups world-wide indicate that nuclear location and organization are drivers of genome functions, which in cooperation with other features including epigenetic marks, non-coding RNAs and trans-factor binding bring about genome control. Thus, genome spatial organization can be considered on a par with other epigenetic features that together contribute to overall genome control. The classical paradigm of early mammalian development arguably represents the most dramatic and yet least understood process of genome reprogramming, where a single cell undergoes a series of divisions to ultimately give rise to the hundreds of different cell types found in a mature organism. Study of pre-implantation embryo development is hindered by the very nature of the life form, composed of extremely low cell numbers at each stage, which severely limits the options for investigation. My lab has recently developed a novel technique called single cell Hi-C, which has the power to detect tens of thousands of simultaneous chromatin contacts from a single cell. In this application I propose to apply this technology to study chromosome structure and genome organization during mouse pre-implantation development along with single cell transcriptome analyses from the same cells."

2 401 393 €

Start date: 2014-02-01, End date: 2019-01-31

Overview: This project will set a new agenda and direction for the study of political campaigns. It will examine whether and how new digital technologies are transforming election campaigns and citizen behaviour in new and established democracies. More specifically, it will assess claims that democracies are now entering a new data-driven era of political campaigning that is profoundly reconfiguring how campaigns’ are run, who runs them and their implications for the quality of voter decision-making, the vibrancy of political parties and ultimately, the future of representative democracy. It will do so in three main stages: (1) First, it will define what data-driven campaigning is and critically assess whether it forms new and distinct era of electioneering in conceptual and historical terms? In particular, it will argue that the two key traits of this new mode of campaigning are the increased individualization or micro-targeting of party messages and the automated use of misinformation to mobilize and persuade voters. (2) Based on this definition it will map the ‘supply’ of the new mode of campaigning across new and older democracies by designing an innovative new index to compare use of data-driven techniques by parties. Where is it most commonly seen and why are some parties and countries more likely to promote its growth? (3) Finally, it will assess the impact of these new methods on key political actors and assess the consequences for the longer term future of liberal democracy. Does use of these techniques help counter recent declines in voter turnout by identifying under-mobilized groups? Or, do they ensure parties focus on the already engaged, bypassing those that are harder to reach? Can data-driven campaigning improve citizen choices by giving them the information on the issues they primarily care about or does it help to increase disinformation and even manipulation of voter choices?

2 499 394 €

Start date: 2019-11-01, End date: 2024-10-31

DISCONEX investigates two types of text-processing practices by means of which academic researchers are classified in different national and disciplinary fields of the social sciences and humanities (SSH). The research project will produce theoretically informed and empirically grounded insights into the social organization of SSH research. Drawing from constructivist social theory and qualitative methods in discourse analysis and pragmatics, the research team investigates the discursive construction of excellence as a practical accomplishment of readers cooperating with texts. In a first step, we collect CVs from confirmed SSH researchers from France, Germany, the UK and the U.S.. Then we carry out reader interviews to investigate how membership is negotiated in specialized knowledge communities of the SSH. In a second step, we investigate non-academic practices of processing large text collections in order to account for how academic producers are ranked by evaluation professionals and calculative technologies. Finally, by comparing representations of excellence produced by academic and non-academic actors, DISCONEX will show how knowledge producers and ranking experts account for the representations of other types of readers respectively. In the light of the complex interpretive problems involved in the reading and writing of academic texts, we will produce reflexive knowledge on how SSH researchers are classified in the light of new modes of academic knowledge production. Given the important role that written texts play in SSH discourse, the exchange between the sociology of science and discourse analysis can help establish a new field: the social sciences and humanities studies (SSHS).

1 498 959 €

Start date: 2013-03-01, End date: 2018-08-31

The increasing use of armed, uninhabited aircraft (drones) is a serious political challenge with implications for security and justice worldwide. Drone technology is attracting high levels of investment, drones controlled remotely are becoming more numerous, and technological momentum toward drones controlled by artificial intelligence (AI) is building. Many human lives are at stake in this, so the violent use of drones continues to raise ethical questions. DRONETHICS will systematically address an urgent need to clarify the morality of ‘drone violence’, defined as violence involving a weapon system that is radically remote from its immediate user. Such remoteness is achieved through extreme physical distancing or the devolution of agency from humans to machines, so drone violence disrupts traditional expectations about war and a warrior’s exposure to risk. In turn, the disruptively innovative premise of this project is that such violence does not necessarily fall within the remit of the Just War framework according to which war is traditionally judged and governed. Moving beyond state-of-the-art Just War thinking, the project opens up an ethical inquiry into drone violence conceptualised as either war, law enforcement, interpersonal violence, or devolved (to AI) violence. An interdisciplinary research team, incorporating international relations, moral philosophy and computer science perspectives, will conduct rigorous analysis of documentary sources and engage closely with officials, drone operators, and roboticists. Through innovative exploration and application of alternative frameworks for governing violence, DRONETHICS will produce: the first integrated conceptual framework for explaining ethical concerns arising from current and potential forms of drone violence; concrete recommendations for policy-makers on how to manage this violence ethically; and a new normative vision for shaping the longer-term trajectory of drone violence for the good of all humanity.

1 359 348 €

Start date: 2018-07-01, End date: 2022-06-30

Development of any organism starts with a totipotent cell (zygote). Through series of cell divisions and differentiation processes this cell will eventually give rise to the whole organism containing hundreds of specialised cell. While the cells at the onset of development have the capacity to generate all cell types (ie are toti-or pluripotent), this developmental capacity is progressively lost as the cells undertake cell fate decisions. At the molecular level, the memory of these events is laid down in a complex layer of epigenetic modifications at both the DNA and the chromatin level. Unidirectional character of the developmental progress dictates that the key acquired epigenetic modifications are stable and inherited through subsequent cell divisions. This paradigm is, however, challenged during cellular reprogramming that requires de-differentiation (nuclear transfer, induced pluripotent stem cells, wound healing and regeneration in lower organisms) or a change in cell fate (transdifferentiation). Despite intense efforts of numerous research teams, the molecular mechanisms of these processes remain enigmatic. In order to understand cellular reprogramming at the molecular level, this proposal takes advantage of epigenetic reprogramming processes that occur naturally during mouse development. By using mouse fertilised zygote and mouse developing primordial germ cells we will investigate novel molecular components implicated in the genome-wide erasure of DNA methylation. Additionally, by using a unique combination of the developmental models with the state of the art ultra-sensitive LC/MS and genomics approaches we propose to investigate the dynamics and the interplay between DNA and RNA modifications during these key periods of embryonic development characterised by genome-wide epigenetic changes . Our work will thus provide new fundamental insights into a complex dynamics and interactions between epigenetic modifications that underlie epigenetic reprogramming

2 000 000 €

Start date: 2015-08-01, End date: 2020-07-31

The first 150 M.yrs of Earth evolution were the most dramatic in the history of the planet, setting the scene for the development of plate tectonics, the Earth’s magnetic field and the origin of life. By the end of this period Earth had separated into core, mantle, crust and atmosphere and the Moon had formed by, it is presumed, a giant impact near the end of accretion. The aim of this project is to quantify the processes by which, during Earth’s earliest evolution, the chemical elements were distributed into different geological reservoirs, to determine the timings and conditions under which this partitioning occurred and to determine how Earth’s interior reached its current composition and oxidation state. The principal method involves experiments at high temperatures (1400-3000K) and high pressures (0-25 GPa, equivalent to 0-700 km depth) in which the silicate materials of Earth’s mantle, crust and core are equilibrated with one another and with a gas phase under controlled conditions. Elements which constrain the major processes of growth and differentiation of the Earth are added to each experiment in trace concentrations similar to those found on Earth. After the experiment the products (typically 2-60 mgm) are sectioned and their chemical compositions determined by microanalysis. By varying the experimental conditions the dependence of the geochemical behaviour of the different elements on physical conditions such as pressure, temperature and oxidation state will be determined. These measurements of chemical fractionations between different phases are complemented by experimentally-measured isotopic fractionations between the same phases. These will enable us to interpret the observed isotopic differences between Earth and primitive planetary material (as represented by chondritic meteorites) in terms of the processes which formed our planet.

2 498 761 €

Start date: 2011-04-01, End date: 2017-03-31

"Media reporting on the economy is never far from controversy. Academic economists and the public regularly find journalists at fault in their interpretation of events and prescription of solutions. Past scholarship has sought to locate the biases of journalists in political and institutional contexts. This project takes a novel approach by studying “economic journalism” as a site for the production of public economic knowledge. The practices of journalists are examined to reveal how they parse competing claims of expertise by academic economists, other social scientists and by laymen. The second half of the twentieth century was witness to increased homogeneity in academic economics and interdependence of national economies, yet the content and style of “economic journalism” has remained distinctive across nations. This project sets out to understand how and why media representation of economic knowledge has remained distinctively different even while the content and style of economics converged internationally. The project aims to understand this differentiation by focusing on three international economic controversies: the reconstruction debate post 1945, the monetary and oil crisis of the 1970s, and the current economic crisis; across five nations: USA, UK, France, Argentina, and Brazil. It combines archival research, oral history, ethnographic observation, content and textual analysis of media, to identify media representations of economic expertise and reveal how they are shaped by historical and cultural contexts. Cultural standards of trust, the history and economics of the media, and the history of economics and social movements explain the emergence of distinct national genres of “economic journalism.” The project offers a original perspective on how public knowledge of the economy is a iterative process engaging journalists, academics and laymen and explores its implications for the possibilities of public support for economic actions and policies."

1 458 041 €

Start date: 2012-01-01, End date: 2016-12-31

‘I hate Brexiteers, they betrayed my future’. Those words of an 18 year old on Brexit Referendum Night represent a growing and worrying phenomenon: electoral hostility. Electoral disagreements have long been seen as results of social divisions, but recent research shows that they have become a basis of antagonism in their own right in the US. Two comparative pilots I ran also found electoral hostility widespread in recent French and British elections but rare in South Africa and Australia. In the UK Brexit referendum, 51% of citizens felt anger towards opposite voters and 46% disgust. I define electoral hostility as negative feelings (frustration, anger, contempt, disgust) held towards individuals or groups as a result of their effective or perceived electoral preferences. It may occur in the campaign, post-election, and reinforce into self-perpetuating cycles of hostility as it is structured as a Mokken scale which can become ‘stages’ of hostility. While scepticism of political elites is well-studied, hostility towards fellow voters takes electoral negativity to a new level. Electoral hostility may have far reaching consequences, leading citizens to resent one another due to electoral stances and drift apart in increasingly divided societies, but also to the delegitimization of electoral outcomes and negative attitudes towards solidarity. ELHO will answer the following research question: What are the causes and consequences of electoral hostility at individual, group, and aggregate levels and how does it develop over time? The project’s innovative methods combine a 27 country multi-level panel survey, visual, physiological and field experiments, election diaries, family focus groups, a scoping survey of Election Management Bodies, and campaign and atmosphere coding. The project will also explore possible mitigation in ambitious partnership with psychiatrists, ergonomists, lawyers, EMBs and IGOs creating new Electoral Hostility Research Centre and Observatory.

2 499 838 €

Start date: 2019-04-01, End date: 2024-03-31

This project examines how predicted economic growth is experienced by people in Mongolia with the advent of large-scale mining operations. Our project will generate new insight into two areas of concern for economic anthropology and beyond. First we will examine the way that the economy is unfolding in a distinct way in East Asia through different kinds of predictive narratives that come to have an effect on the way people act. Second we will explore how individual subjects also shape the economy in their everyday relations through various forms of exchange and the accumulation of wealth. This dual focus provides the basis for a nuanced and powerful critique of our understanding of the way in which economic realities are shaped through predictive narratives as well as formed, from the ground-up, by local actors who carve out new forms of subjectivity through such actions. Indeed it is our suggestion that these new subjects of the growing economy are distinctly different from the post-socialist selves described in previous literature on the region. Instead they are powerful and hopeful subjects who demand a different kind of engagement and entitlement. The form such engagement takes and the kind of economic realities produced out of such forms is the focus of our study.

1 658 373 €

Start date: 2014-09-01, End date: 2019-06-30

We intend to achieve a step change in our understanding of the mechanistic basis of epigenetic regulation. We will capitalize on a plant epigenetic silencing system, vernalization, which has many features that allow the complete dissection of different facets of epigenetic regulation. In addition, the silencing is quantitatively modulated by the environment enabling dissection of how external cues mediate epigenetic silencing. We will combine genetics, molecular biology and biochemical approaches with computational modelling to allow us to translate the extensive nuts and bolts information into an understanding of how the engine works. A particular strength of modelling will be its predictive nature and ability to distinguish between key components and those with subsidiary or redundant roles. The system we will use is vernalization, the cold-induced Polycomb-silencing of the target locus, FLC. We will dissect the many phases of vernalization: the triggering of FLC repression by prolonged cold; the nucleation and epigenetic stability of chromatin changes at FLC; and the spreading of the silencing yet spatial restriction to FLC. Our goal will be a full understanding of the complexity involved in the epigenetic silencing of this locus, described in a quantitative model that reveals how the silencing is induced by temperature and how individual components of the silencing network are integrated into a robust whole. This ambitious goal, which will uncover fundamental concepts important to gene regulation in many organisms, will be achieved through a tight integration of molecular analysis and computational modelling, enabling efficient cycling between experimentation, prediction and validation.

2 450 000 €

Start date: 2009-01-01, End date: 2013-12-31

To what extent can international institutions learn? What factors determine whether such institutions develop capacities for self-awareness and endogenous institutional change? This project investigates these questions in the context of the European Union (EU). Specifically, it examines the dramatic expansion in security missions led by the EU since 2003, a capacity that many observers doubted was even possible for the EU. To explain this change in institutional behaviour, the project intends to develop a theory of institutional learning to analyze the EU’s instigation and implementation of 16 security operations in various regions under the auspices of the European Security and Defence Policy (ESDP). In addition, with these missions the EU has shown a growing capacity to innovate in security affairs, using a unique civilian crisis management (CCM) capacity linked to security sector reform and other EU policy tools, including the ESDP, the Common Foreign and Security Policy (CFSP), and the European Neighbourhood Policy (ENP). These changes demand further examination in light of not only the growing ambitions of the EU itself but also in terms of the increasing demands for security assistance placed on a variety of IOs, such as the UN, NATO, and the OSCE. The initial phase of the project will focus on four key ESDP operations as detailed case studies – Macedonia, the Palestinian Authority, the Democratic Republic of the Congo, and Bosnia-Hercegovina – to explain this innovation. Following the investigation of these representative cases, the later stages of the project will examine more recent EU security operations in hopes of developing a general theory of EU institutional learning in the area of foreign/security/defence policy. The project also hopes to generalize beyond this theory to other EU policy domains and, potentially, other IOs at the regional and global levels. In doing so the findings could have major implications for global governance.

1 019 264 €

Start date: 2008-05-01, End date: 2013-04-30

Plate tectonics has been a fundamental tenet of Earth Science for nearly 50 years, but fundamental questions remain, such as where is the base of the plate and what makes a plate, “plate-like?” A better understanding of the transition from the rigid lithospheric plate to the weaker mantle beneath – the rheological lithosphere-asthenosphere boundary (LAB) - has important implications for the driving forces of plate tectonics, natural hazard mitigation, mantle dynamics, the evolution of the planet, and climate change. There are many proxies used to estimate the depth and nature of the base of tectonic plates, but to date no consensus has been reached. For example, temperature is known to have a strong effect on the mechanical behaviour of rocks. However, it has also been suggested that the chemical composition of the plate provides additional strength or that melt weakens the mantle beneath the plate. We are at a critical juncture where large-scale efforts using geophysical, geochemical, and geological techniques are being launched to better understand the definition of the tectonic plate. The simple and short history of the ocean plate makes it the ideal location to advance our understanding. However, imaging the oceanic LAB has proved challenging given the remoteness of the oceans and associated difficulties in instrumentation. Most observations come from only one ocean, the Pacific, from indirect, remote observations, at different areas and scales. I propose a large-scale effort to systematically image an oceanic plate beneath the Atlantic from birth at ridge to 40 My old seafloor. I will deploy ocean bottom seismometers (OBS) and magnetotelluric (MT) instruments, and I will image the plate at a range of resolution scales (laterally and in depth) and sensitivities to physical and chemical properties. This large, focused, interdisciplinary effort will finally determine the processes and properties that make a plate strong and define it.

1 827 855 €

Start date: 2016-04-01, End date: 2021-03-31

"Tumorigenesis is a form of somatic evolution, a topical subject given the advent of cancer genome sequencing. However, we contend that some features of Darwinian evolution have been neglected when cancer is studied, as have some aspects of evolution that are special to cancers. For example, tumours comprise an expanding population of cells, cancers must occur within a normal human lifespan, and genotypes detrimental to growth of the tumour as a whole may be selected. These factors may render invalid the classical model in which successive mutations with large advantages arise and spread through the tumour in selective sweeps. To incorporate these neglected features and to test how tumorigenesis depends on factors such as mutation rate, selection and size constraints, we shall set up a comprehensive model of tumour growth incorporating cell birth, death, division and mutation parameters. We shall examine specific aspects of cancer-as-evolution in mice. By marking mutant clones using fluorescent proteins, we can track them and see how they persist, spread and die. We shall also determine the mutation profiles and genetic diversity of mutant clones and whole tumours in mice and humans using next-generation sequencing. Specific experiments will determine: (i) the fate of new advantageous clones arising in an existing tumour; (ii) whether new disadvantageous clones can persist in tumours; (iii) whether apparently maladaptive traits for tumour growth, such as suppressing the growth of competitors, can be selected; (iv) why do housekeeper gene mutations cause cancer in specific sites; (v) can cancer cells have too much genomic instability; and (vi) whether all cancers develop owing to driver mutations with big effects, or are there “mini-drivers” of tumorigenesis? There will be continual cross-talk between the experimental and modelling work. The results of the project will enhance our basic understanding of tumorigenesis and suggest strategies for anticancer therapy."

2 500 000 €

Start date: 2014-09-01, End date: 2019-08-31

This project will explore how exposure to political violence in a civil conflict context impacts upon social, economic and political behavior of individuals. It has three legs. In the first leg I will analyze the association between political and domestic violence. Specifically, I will test the hypothesis that those exposed to political violence are more likely to be perpetrators of domestic violence. In the second leg I will analyze whether exposure to political violence impacts upon economic behavior. Specifically, I will analyze the impact of exposure on risk, time and social preferences, savings behavior, employment, and earnings. Finally, in the third leg I will look into political behavior. Specifically, I will analyze the association between exposure to political violence and political participation and support, political tolerance, ideology, voting behavior, and party choice. The project will make use of a natural experiment setting that the institutional setup and the long-running civil conflict in Turkey create. Turkey has a mandatory military service system that requires each Turkish man, when he comes to age, to serve in the army for about a year. Those drafted are first subject to a basic training program and then, via a lottery, are randomly assigned to military bases all over the country to serve the rest of their terms. This means a young soldier can be sent to a military base in Eastern or Southeastern Turkey where a bloody armed conflict between the Turkish armed forces and the insurgent organization PKK has been going on since August 1984, and thus, can get actively involved in the armed conflict. This is a natural experiment setting that randomly exposes young Turkish males to political violence. In this project I aim to study whether and how that exposure impacts upon social, economic and political behavior of the exposed. To accomplish these goals, two independent, large-n survey studies will be designed and conducted in Turkey.

938 184 €

Start date: 2017-04-01, End date: 2022-03-31

"Despite intensive abatement efforts, airborne particulate matter remains a major public health issue with costs across the European Union estimated at 600 billion euros in 2005. Road traffic remains one of the major sources of particulate matter, and diesel emissions are by far the largest source of atmospheric nanoparticles in urban areas. Semi-volatile organic compounds emitted largely in the condensed matter phase are a major component of diesel emissions, and as primary particles are advected from their road traffic source, the semi-volatile compounds vaporise and are oxidised, forming a greater mass of secondary organic aerosol (SOA). However, the semi-volatile compounds are extremely poorly characterised as they are not resolved by traditional gas chromatographic methods, presenting an unresolved complex mixture (UCM). For this reason, despite being a major precursor of SOA, such compounds are often poorly represented or completely omitted from atmospheric chemistry-transport models. This proposal is concerned with applying new two dimensional gas chromatographic methods to characterisation of the UCM at a molecular level which will be followed by studies of the physico-chemical properties of representative components of the semi-volatile emissions. The very abundant nucleation nanoparticle mode of diesel emissions is comprised almost entirely of semi-volatile organic material and hence these particles are progressively lost from the atmosphere by evaporation. Until now, there has been insufficient knowledge of the properties of the semi-volatile components to model this behaviour reliably. Such processes will be quantified through both controlled laboratory studies and carefully designed field measurements. Numerical models on both a street canyon and a neighbourhood (5x5 km) scale will be developed to simulate the key processes, such that spatial patterns and size distributions will be predicted, and compared with independent measurements."

2 394 959 €

Start date: 2013-04-01, End date: 2018-03-31

Designating Protected Areas (PAs) is the most important policy tool for biodiversity conservation. Over 100 new PAs have been established in the past 36 months in European Union territory. However, effective management of PAs is often obstructed by conflicts mainly associated with the social impacts (SIs) imposed on local communities by their establishment. Despite the importance of these SIs there are certain aspects in this field that remain significantly under-researched. There is now an increasing need to incorporate SI assessments in decision making processes by providing a clear framework explaining how perceptions of these impacts are created and predicting their change in the future. This will support the achievement of international goals for biodiversity conservation and adaptation to climate change as well as better accounting for social justice issues for communities dependent on protected natural resources. The aim of FIDELIO is to develop for the first time a new paradigm in order to understand how perceptions of SIs are formulated taking into consideration the dimensions of space and time. FIDELIO will assist in increasing public engagement and the incorporation of local opinions in decision-making. It will also facilitate the process of policy development and a reduction in conflicts between different stakeholders in PAs. FIDELIO will last 5 years and its research objectives will be explored through the application of a mixed-methods approach including the implementation of two rounds of social surveys in 4 PAs across Europe and the testing of the framework in 15 additional PAs. This is an extremely timely project considering the steady increase of new PAs and the re-designation of current ones. FIDELIO will contribute to the better understanding of SIs and facilitate predictions for their change in the future, while assisting in maximizing social benefits for local communities arising from the designation of a PA.

1 495 786 €

Start date: 2019-02-01, End date: 2024-01-31

We know how to map tropical forest biomass using an array of satellite and aircraft sensors with reasonable accuracy (±15-40 %). However, we do not know how to map biomass change. Simply differencing existing biomass maps produces noisy and biased results, with confidence intervals unknowable using existing static field plots. Thus the potential for using plentiful free satellite data for biomass change mapping is being wasted. To solve this I propose setting up the first experimental arrays of biomass change plots. In total 52 large plots will be located in logging concessions in Gabon and Peru, where biomass will be assessed before and after logging, and during recovery. In addition to traditional field inventory, terrestrial laser scanning (TLS) data will give the precise 3D shape of thousands of trees before and after disturbance, allowing biomass change to be estimated without bias. The project’s unmanned aerial vehicle (UAV) will collect LiDAR data 4 times over each concession over 4 years, scaling up the field data to give thousands of hectares of biomass change data. In tandem, data from all potentially useful satellites (17+) flying over the field sites over the study period will be ordered and processed. These data will enable the development of new methods for mapping carbon stock changes, with known uncertainty, which I will scale up across the Amazon basin and west/central Africa. For the first time we will have the methods to assess the balance of regrowth and anthropogenic disturbance across tropical forests, informing us about the status and resilience of the land surface carbon sink. As well as of scientific interest, these results are urgently needed for forest conservation: the Paris Agreement relies on paying countries to reduce losses and enhance gains in forest carbon stocks, but we do not currently have the tools to map forest carbon stock changes. Without accurate monitoring it is not possible to target resources nor assess success.

1 942 471 €

Start date: 2018-01-01, End date: 2022-12-31

Feedbacks between plants and soil under environmental change are likely to have a significant impact on ecosystem carbon cycling. Recent work has shown that increased atmospheric carbon dioxide concentrations have enhanced tree growth in forests. However these increases in growth can also cause ‘priming effects’ whereby microbial degradation of soil organic matter is stimulated by fresh carbon inputs, such as plant litter, releasing additional carbon from the soil. Given that forest soils represent the largest terrestrial carbon pool, priming effects could cause a major release of carbon dioxide to the atmosphere. Despite their potential importance in ecosystem carbon dynamics under environmental change, the processes and mechanisms underlying priming effects are still poorly understood. This is in part due to the enormous disparities in the experimental scales and methods required to study microbial processes vs. ecosystem carbon dynamics and the difficulties in extrapolating the results of laboratory studies to the ecosystem level. This project will significantly advance our understanding of the role of priming effects in forest carbon dynamics in different forest types and reconcile the experimental problems of scale using multidisciplinary nested studies across multiple scales. The nested design will explicitly test the validity of extrapolations made at one scale to predict effects at another. The ultimate aim is to allow the extrapolation of results from small-scale studies of priming to the ecosystem level for a wide range of forests. The results will establish this fundamentally new approach as a widely applicable method in the study of plant-soil feedbacks. This research will provide the first comprehensive comparative dataset on priming effects across forests worldwide and form the solid basis for their inclusion in model predictions of forest carbon cycling under future global change.

1 694 796 €

Start date: 2012-12-01, End date: 2018-05-31