Project acronym ADaPTIVE
Project Analysing Diversity with a Phenomic approach: Trends in Vertebrate Evolution
Researcher (PI) Anjali Goswami
Host Institution (HI) NATURAL HISTORY MUSEUM
Call Details Starting Grant (StG), LS8, ERC-2014-STG
Summary What processes shape vertebrate diversity through deep time? Approaches to this question can focus on many different factors, from life history and ecology to large-scale environmental change and extinction. To date, the majority of studies on the evolution of vertebrate diversity have focused on relatively simple metrics, specifically taxon counts or univariate measures, such as body size. However, multivariate morphological data provides a more complete picture of evolutionary and palaeoecological change. Morphological data can also bridge deep-time palaeobiological analyses with studies of the genetic and developmental factors that shape variation and must also influence large-scale patterns of evolutionary change. Thus, accurately reconstructing the patterns and processes underlying evolution requires an approach that can fully represent an organism’s phenome, the sum total of their observable traits.
Recent advances in imaging and data analysis allow large-scale study of phenomic evolution. In this project, I propose to quantitatively analyse the deep-time evolutionary diversity of tetrapods (amphibians, reptiles, birds, and mammals). Specifically, I will apply and extend new imaging, morphometric, and analytical tools to construct a multivariate phenomic dataset for living and extinct tetrapods from 3-D scans. I will use these data to rigorously compare extinction selectivity, timing, pace, and shape of adaptive radiations, and ecomorphological response to large-scale climatic shifts across all tetrapod clades. To do so, I will quantify morphological diversity (disparity) and rates of evolution spanning over 300 million years of tetrapod history. I will further analyse the evolution of phenotypic integration by quantifying not just the traits themselves, but changes in the relationships among traits, which reflect the genetic, developmental, and functional interactions that shape variation, the raw material for natural selection.
Summary
What processes shape vertebrate diversity through deep time? Approaches to this question can focus on many different factors, from life history and ecology to large-scale environmental change and extinction. To date, the majority of studies on the evolution of vertebrate diversity have focused on relatively simple metrics, specifically taxon counts or univariate measures, such as body size. However, multivariate morphological data provides a more complete picture of evolutionary and palaeoecological change. Morphological data can also bridge deep-time palaeobiological analyses with studies of the genetic and developmental factors that shape variation and must also influence large-scale patterns of evolutionary change. Thus, accurately reconstructing the patterns and processes underlying evolution requires an approach that can fully represent an organism’s phenome, the sum total of their observable traits.
Recent advances in imaging and data analysis allow large-scale study of phenomic evolution. In this project, I propose to quantitatively analyse the deep-time evolutionary diversity of tetrapods (amphibians, reptiles, birds, and mammals). Specifically, I will apply and extend new imaging, morphometric, and analytical tools to construct a multivariate phenomic dataset for living and extinct tetrapods from 3-D scans. I will use these data to rigorously compare extinction selectivity, timing, pace, and shape of adaptive radiations, and ecomorphological response to large-scale climatic shifts across all tetrapod clades. To do so, I will quantify morphological diversity (disparity) and rates of evolution spanning over 300 million years of tetrapod history. I will further analyse the evolution of phenotypic integration by quantifying not just the traits themselves, but changes in the relationships among traits, which reflect the genetic, developmental, and functional interactions that shape variation, the raw material for natural selection.
Max ERC Funding
1 482 818 €
Duration
Start date: 2015-06-01, End date: 2020-05-31
Project acronym AFRIGOS
Project African Governance and Space: Transport Corridors, Border Towns and Port Cities in Transition
Researcher (PI) Paul Christopher Nugent
Host Institution (HI) THE UNIVERSITY OF EDINBURGH
Call Details Advanced Grant (AdG), SH2, ERC-2014-ADG
Summary AFRIGOS investigates the process of 'respacing' Africa, a political drive towards regional and continental integration, on the one hand, and the re-casting of Africa's engagement with the global economy, on the other. This is reflected in unprecedented levels of investment in physical and communications infrastructure, and the outsourcing of key functions of Customs, Immigration and security agencies. AFRIGOS poses the question of how far respacing is genuinely forging institutions that are facilitating or obstructing the movement of people and goods; that are enabling or preventing urban and border spaces from being more effectively and responsively governed; and that take into account the needs of African populations whose livelihoods are rooted in mobility and informality. The principal research questions are approached through a comparative study of port cities, border towns and other strategic nodes situated along the busiest transport corridors in East, Central, West and Southern Africa. These represent sites of remarkable dynamism and cosmopolitanism, which reflects their role in connecting African urban centres to each other and to other global cities.
AFRIGOS considers how governance 'assemblages' are forged at different scales and is explicitly comparative. It works through 5 connected Streams that address specific questions: 1. AGENDA-SETTING is concerned with policy (re-)formulation. 2. PERIPHERAL URBANISM examines governance in border towns and port cities. 3. BORDER WORKERS addresses everyday governance emerging through the interaction of officials and others who make their livelihoods from the border. 4. CONNECTIVE INFRASTRUCTURE looks as the transformative effects of new technologies. 5. PEOPLE & GOODS IN MOTION traces the passage of people and goods and the regimes of regulation to which they are subjected. AFRIGOS contributes to interdisciplinary research on borderland studies, multi-level governance and the everyday state.
Summary
AFRIGOS investigates the process of 'respacing' Africa, a political drive towards regional and continental integration, on the one hand, and the re-casting of Africa's engagement with the global economy, on the other. This is reflected in unprecedented levels of investment in physical and communications infrastructure, and the outsourcing of key functions of Customs, Immigration and security agencies. AFRIGOS poses the question of how far respacing is genuinely forging institutions that are facilitating or obstructing the movement of people and goods; that are enabling or preventing urban and border spaces from being more effectively and responsively governed; and that take into account the needs of African populations whose livelihoods are rooted in mobility and informality. The principal research questions are approached through a comparative study of port cities, border towns and other strategic nodes situated along the busiest transport corridors in East, Central, West and Southern Africa. These represent sites of remarkable dynamism and cosmopolitanism, which reflects their role in connecting African urban centres to each other and to other global cities.
AFRIGOS considers how governance 'assemblages' are forged at different scales and is explicitly comparative. It works through 5 connected Streams that address specific questions: 1. AGENDA-SETTING is concerned with policy (re-)formulation. 2. PERIPHERAL URBANISM examines governance in border towns and port cities. 3. BORDER WORKERS addresses everyday governance emerging through the interaction of officials and others who make their livelihoods from the border. 4. CONNECTIVE INFRASTRUCTURE looks as the transformative effects of new technologies. 5. PEOPLE & GOODS IN MOTION traces the passage of people and goods and the regimes of regulation to which they are subjected. AFRIGOS contributes to interdisciplinary research on borderland studies, multi-level governance and the everyday state.
Max ERC Funding
2 491 364 €
Duration
Start date: 2016-01-01, End date: 2020-12-31
Project acronym AnCon
Project A Comparative Anthropology of Conscience, Ethics and Human Rights
Researcher (PI) Tobias William Kelly
Host Institution (HI) THE UNIVERSITY OF EDINBURGH
Call Details Consolidator Grant (CoG), SH2, ERC-2014-CoG
Summary This project is a comparative anthropology of conscience, ethics and human rights. Numerous international human rights documents formally declare their commitment to protect freedom of conscience. But, what is conscience and how do we know it when we see it? How do we distinguish it from self-interest or fanaticism? And what happens when the concept, often associated with a distinct Christian or liberal history, travels across cultural boundaries? The project will examine the cultural conditions under which claims to conscience are made possible, and the types of claims that are most persuasive when doing so. The project addresses these issues through the comparative analysis of three case studies: British pacifists, Sri Lankan activists, and Soviet dissidents. These case studies have been carefully chosen to provide globally significant, but contrasting examples of contests over the implications of claims to conscience. If claims of conscience are often associated with a specifically liberal and Christian tradition, mid-twentieth century Britain can be said to stand at the centre of that tradition. Sri Lanka represents a particularly fraught post-colonial South Asian counterpoint, wracked by nationalist violence, and influenced by ethical traditions associated with forms of Hinduism and Buddhism. Soviet Russia represents a further contrast, a totalitarian regime, where atheism was the dominant ethical language. Finally, the project will return specifically to international human rights institutions, examining the history of the category of conscience in the UN human rights system. This project will be ground breaking, employing novel methods and analytical insights, in order to producing the first comparative analysis of the cultural and political salience of claims of conscience. In doing so, the research aims to transform our understandings of the limits and potentials of attempts to protect freedom of conscience.
Summary
This project is a comparative anthropology of conscience, ethics and human rights. Numerous international human rights documents formally declare their commitment to protect freedom of conscience. But, what is conscience and how do we know it when we see it? How do we distinguish it from self-interest or fanaticism? And what happens when the concept, often associated with a distinct Christian or liberal history, travels across cultural boundaries? The project will examine the cultural conditions under which claims to conscience are made possible, and the types of claims that are most persuasive when doing so. The project addresses these issues through the comparative analysis of three case studies: British pacifists, Sri Lankan activists, and Soviet dissidents. These case studies have been carefully chosen to provide globally significant, but contrasting examples of contests over the implications of claims to conscience. If claims of conscience are often associated with a specifically liberal and Christian tradition, mid-twentieth century Britain can be said to stand at the centre of that tradition. Sri Lanka represents a particularly fraught post-colonial South Asian counterpoint, wracked by nationalist violence, and influenced by ethical traditions associated with forms of Hinduism and Buddhism. Soviet Russia represents a further contrast, a totalitarian regime, where atheism was the dominant ethical language. Finally, the project will return specifically to international human rights institutions, examining the history of the category of conscience in the UN human rights system. This project will be ground breaking, employing novel methods and analytical insights, in order to producing the first comparative analysis of the cultural and political salience of claims of conscience. In doing so, the research aims to transform our understandings of the limits and potentials of attempts to protect freedom of conscience.
Max ERC Funding
1 457 869 €
Duration
Start date: 2015-08-01, End date: 2020-07-31
Project acronym BeeDanceGap
Project Honeybee communication: animal social learning at the height of social complexity
Researcher (PI) Ellouise Leadbeater
Host Institution (HI) ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE
Call Details Starting Grant (StG), LS8, ERC-2014-STG
Summary Learning from others is fundamental to ecological success across the animal kingdom, but a key theme to emerge from recent research is that individuals respond differently to social information. Understanding this diversity is an imposing challenge, because it is hard to replicate the overwhelming complexity of free-living groups within controlled laboratory conditions. Yet here I propose that one of the most complex social models that we know of— the sophisticated eusocial societies of honeybees— offer unrivaled and yet unrecognized potential to study social information flow through a natural group. The honeybee “dance language” is one of the most celebrated communication systems in the animal world, and central to a powerful information network that drives our most high-profile pollinator to food, but bee colonies are uniquely tractable for two reasons. Firstly, next-generation transcriptomics could allow us to delve deep into this complexity at the molecular level, on a scale that is simply not available in vertebrate social systems. I propose to track information flow through a natural group using brain gene expression profiles, to understand how dances elicit learning in the bee brain. Secondly, although bee foraging ranges are vast and diverse, social learning takes place in one centralized location (the hive). The social sciences now offer powerful new tools to analyze social networks, and I will use a cutting-edge network-based modelling approach to understand how the importance of social learning mechanisms shifts with ecology. In the face of global pollinator decline, understanding the contribution of foraging drivers to colony success has never been more pressing, but the importance of the dance language reaches far beyond food security concerns. This research integrates proximate and ultimate perspectives to produce a comprehensive, multi-disciplinary program; a high-risk, high-gain journey into new territory for understanding animal communication.
Summary
Learning from others is fundamental to ecological success across the animal kingdom, but a key theme to emerge from recent research is that individuals respond differently to social information. Understanding this diversity is an imposing challenge, because it is hard to replicate the overwhelming complexity of free-living groups within controlled laboratory conditions. Yet here I propose that one of the most complex social models that we know of— the sophisticated eusocial societies of honeybees— offer unrivaled and yet unrecognized potential to study social information flow through a natural group. The honeybee “dance language” is one of the most celebrated communication systems in the animal world, and central to a powerful information network that drives our most high-profile pollinator to food, but bee colonies are uniquely tractable for two reasons. Firstly, next-generation transcriptomics could allow us to delve deep into this complexity at the molecular level, on a scale that is simply not available in vertebrate social systems. I propose to track information flow through a natural group using brain gene expression profiles, to understand how dances elicit learning in the bee brain. Secondly, although bee foraging ranges are vast and diverse, social learning takes place in one centralized location (the hive). The social sciences now offer powerful new tools to analyze social networks, and I will use a cutting-edge network-based modelling approach to understand how the importance of social learning mechanisms shifts with ecology. In the face of global pollinator decline, understanding the contribution of foraging drivers to colony success has never been more pressing, but the importance of the dance language reaches far beyond food security concerns. This research integrates proximate and ultimate perspectives to produce a comprehensive, multi-disciplinary program; a high-risk, high-gain journey into new territory for understanding animal communication.
Max ERC Funding
1 422 010 €
Duration
Start date: 2016-02-01, End date: 2021-01-31
Project acronym COMPEN
Project Penal Policymaking and the prisoner experience: a comparative analysis
Researcher (PI) Benjamin Crewe
Host Institution (HI) THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Call Details Consolidator Grant (CoG), SH2, ERC-2014-CoG
Summary Recent years have seen renewed interest in the political economy of punishment, yet almost no attention has been given to the factors that translate socio-political arrangements into penal practices or the specific nature of imprisonment in different political-economic systems. Based on research in England & Wales and one Nordic nation, the project goals are to expose the dynamics of the penal state and the nature of penality in countries that are considered ‘exclusionary’ and ‘inclusionary’ respectively in their socio-economic and penal practices. These goals will be achieved through four comparative sub-projects: first, a study of penal policymaking and the ‘penal field’ (the players and processes that shape penal policy and practice); second, an exploration of the texture of imprisonment for women and sex offenders, groups presumed to experience inclusionary and exclusionary penal practices in distinctive ways; third, a study of how these prisoners experience entry into and exit from the system; fourth, a study of the ‘deep end’ imprisonment in both countries.
A central aim is to interrogate widespread assumptions about the relative mildness/severity of penal practices in inclusionary and exclusionary nations. The research will employ an emerging framework that conceptualises the prison experience through notions of ‘depth’, ‘weight’, ‘tightness’ and ‘breadth’. It will foreground the roles of shame and guilt in shaping prisoners’ orientations, concepts that feature in theories of offending and reintegration, but are absent from the sociology of imprisonment. Through the concept of ‘penal consciousness’, the project will also explore the interaction between the punitive intentions of the state and prisoners’ perceptions of the purposes and legitimacy of their punishment. The research will be groundbreaking in several ways, reshaping the field of comparative penology, and linking macro issues of the penal state with the lived realities of the prison landings.
Summary
Recent years have seen renewed interest in the political economy of punishment, yet almost no attention has been given to the factors that translate socio-political arrangements into penal practices or the specific nature of imprisonment in different political-economic systems. Based on research in England & Wales and one Nordic nation, the project goals are to expose the dynamics of the penal state and the nature of penality in countries that are considered ‘exclusionary’ and ‘inclusionary’ respectively in their socio-economic and penal practices. These goals will be achieved through four comparative sub-projects: first, a study of penal policymaking and the ‘penal field’ (the players and processes that shape penal policy and practice); second, an exploration of the texture of imprisonment for women and sex offenders, groups presumed to experience inclusionary and exclusionary penal practices in distinctive ways; third, a study of how these prisoners experience entry into and exit from the system; fourth, a study of the ‘deep end’ imprisonment in both countries.
A central aim is to interrogate widespread assumptions about the relative mildness/severity of penal practices in inclusionary and exclusionary nations. The research will employ an emerging framework that conceptualises the prison experience through notions of ‘depth’, ‘weight’, ‘tightness’ and ‘breadth’. It will foreground the roles of shame and guilt in shaping prisoners’ orientations, concepts that feature in theories of offending and reintegration, but are absent from the sociology of imprisonment. Through the concept of ‘penal consciousness’, the project will also explore the interaction between the punitive intentions of the state and prisoners’ perceptions of the purposes and legitimacy of their punishment. The research will be groundbreaking in several ways, reshaping the field of comparative penology, and linking macro issues of the penal state with the lived realities of the prison landings.
Max ERC Funding
1 964 948 €
Duration
Start date: 2015-09-01, End date: 2020-08-31
Project acronym ComplEvol
Project Evolutionary origins of complex ecological adaptations
Researcher (PI) Pascal-Antoine-John- Luc Christin
Host Institution (HI) THE UNIVERSITY OF SHEFFIELD
Call Details Starting Grant (StG), LS8, ERC-2014-STG
Summary During evolution, organisms adapt to diverse environmental conditions by evolving new morphological and/or biochemical traits, some of which are of impressive complexity. This is for example the case of eyes, wings or complex biochemical pathways, which all involve multiple components. The evolution of such complex traits has always intrigued evolutionary biologists, including Charles Darwin, and is still only partially understood. How can natural selection on random mutations lead over time to novel complex ecological adaptations that allow organisms to thrive in diverse environments?
This question will be addressed here by studying a species complex that presents exceptional variation in a key ecological adaptation, namely C4 photosynthesis. This trait results from multiple anatomical and biochemical components that function together to increase plant productivity in warm and dry environments. Capitalizing on a species complex of grasses that includes C4 as well as the ancestral C3 photosynthetic types and multiple intermediate states, the ComplEvol project will combine methods from different fields to infer (i) the history of mutations that generated components for C4 photosynthesis during the dispersal into different ecological conditions, (ii) the factors controlling the spread of these mutations among populations, (iii) the effects of these mutations on the properties of the encoded C4 enzymes, (iv) the effects of different anatomical and biochemical C4 components on the performance of the plants (fundamental niche), and (v) the relationships between these components and the distribution of individuals in contrasted environments (realised niche).
The incorporation of these different dimensions of evolution and ecology will shed new lights on the processes that allow over time the emergence of major ecological novelties through the repeated action of natural selection on minor changes within populations.
Summary
During evolution, organisms adapt to diverse environmental conditions by evolving new morphological and/or biochemical traits, some of which are of impressive complexity. This is for example the case of eyes, wings or complex biochemical pathways, which all involve multiple components. The evolution of such complex traits has always intrigued evolutionary biologists, including Charles Darwin, and is still only partially understood. How can natural selection on random mutations lead over time to novel complex ecological adaptations that allow organisms to thrive in diverse environments?
This question will be addressed here by studying a species complex that presents exceptional variation in a key ecological adaptation, namely C4 photosynthesis. This trait results from multiple anatomical and biochemical components that function together to increase plant productivity in warm and dry environments. Capitalizing on a species complex of grasses that includes C4 as well as the ancestral C3 photosynthetic types and multiple intermediate states, the ComplEvol project will combine methods from different fields to infer (i) the history of mutations that generated components for C4 photosynthesis during the dispersal into different ecological conditions, (ii) the factors controlling the spread of these mutations among populations, (iii) the effects of these mutations on the properties of the encoded C4 enzymes, (iv) the effects of different anatomical and biochemical C4 components on the performance of the plants (fundamental niche), and (v) the relationships between these components and the distribution of individuals in contrasted environments (realised niche).
The incorporation of these different dimensions of evolution and ecology will shed new lights on the processes that allow over time the emergence of major ecological novelties through the repeated action of natural selection on minor changes within populations.
Max ERC Funding
1 498 275 €
Duration
Start date: 2015-06-01, End date: 2020-05-31
Project acronym COMPROP
Project Computational Propaganda:Investigating the Impact of Algorithms and Bots on Political Discourse in Europe
Researcher (PI) Philip Howard
Host Institution (HI) THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Call Details Consolidator Grant (CoG), SH2, ERC-2014-CoG
Summary Social media can have an impressive impact on civic engagement and political discourse. Yet increasingly we find political actors using digital media and automated scripts for social control. Computational propaganda—through bots, botnets, and algorithms—has become one of the most concerning impacts of technology innovation. Unfortunately, bot identification and impact analysis are among the most difficult research challenges facing the social and computer sciences.
COMPROP objectives are to advance a) rigorous social and computer science on bot use, b) critical theory on digital manipulation and political outcomes, c) our understanding of how social media propaganda impacts social movement organization and vitality. This project will innovate through i) “real-time” social and information science actively disseminated to journalists, researchers, policy experts and the interested public, ii) the first detailed data set of political bot activity, iii) deepened expertise through cultivation of a regional expert network able to detect bots and their impact in Europe.
COMPROP will achieve this through multi-method and reflexive work packages: 1) international qualitative fieldwork with teams of bot makers and computer scientists working to detect bots; 2a) construction of an original event data set of incidents of political bot use and 2b) treatment of the data set with fuzzy set and traditional statistics; 3) computational theory for detecting political bots and 4) a sustained dissemination strategy. This project will employ state-of-the-art “network ethnography” techniques, use the latest fuzzy set / qualitative comparative statistics, and advance computational theory on bot detection via cutting-edge algorithmic work enhanced by new crowd-sourcing techniques.
Political bots are already being deployed over social networks in Europe. COMPROP will put the best methods in social and computer science to work on the size of the problem and the possible solutions.
Summary
Social media can have an impressive impact on civic engagement and political discourse. Yet increasingly we find political actors using digital media and automated scripts for social control. Computational propaganda—through bots, botnets, and algorithms—has become one of the most concerning impacts of technology innovation. Unfortunately, bot identification and impact analysis are among the most difficult research challenges facing the social and computer sciences.
COMPROP objectives are to advance a) rigorous social and computer science on bot use, b) critical theory on digital manipulation and political outcomes, c) our understanding of how social media propaganda impacts social movement organization and vitality. This project will innovate through i) “real-time” social and information science actively disseminated to journalists, researchers, policy experts and the interested public, ii) the first detailed data set of political bot activity, iii) deepened expertise through cultivation of a regional expert network able to detect bots and their impact in Europe.
COMPROP will achieve this through multi-method and reflexive work packages: 1) international qualitative fieldwork with teams of bot makers and computer scientists working to detect bots; 2a) construction of an original event data set of incidents of political bot use and 2b) treatment of the data set with fuzzy set and traditional statistics; 3) computational theory for detecting political bots and 4) a sustained dissemination strategy. This project will employ state-of-the-art “network ethnography” techniques, use the latest fuzzy set / qualitative comparative statistics, and advance computational theory on bot detection via cutting-edge algorithmic work enhanced by new crowd-sourcing techniques.
Political bots are already being deployed over social networks in Europe. COMPROP will put the best methods in social and computer science to work on the size of the problem and the possible solutions.
Max ERC Funding
1 980 112 €
Duration
Start date: 2016-01-01, End date: 2020-12-31
Project acronym CONSERVREGCIRCUITRY
Project Conservation and Divergence of Tissue-Specific Transcriptional Regulation
Researcher (PI) Duncan Odom
Host Institution (HI) THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Call Details Starting Grant (StG), LS2, ERC-2007-StG
Summary Vertebrates contain hundreds of different cell types which maintain phenotypic identity by a combination of epigenetic programming and genomic regulation. Systems biology approaches are now used in a number of laboratories to determine how transcription factors and chromatin marks pattern the human genome. Despite high conservation of the cellular and molecular function of many mammalian transcription factors, our recent experiments in matched mouse and human tissues indicates that most transcription factor binding events to DNA are very poorly conserved. A hypothesis that could account for this apparent divergence is that the larger regional pattern of transcription factor binding may be conserved. To test this, (1) we are characterizing the global transcriptional profile, chromatin state, and complete genomic occupancy of a set of tissue-specific transcription factors in hepatocytes of strategically chosen mammals; (2) to further identify the precise mechanistic contribution of cis and trans effects, we are comparing transcription factor binding at homologous regions of human and mouse DNA in a mouse line that carries human chromosome 21. Together, these projects will provide insight into the general principles of how transcriptional networks are evolutionarily conserved to regulate cell fate specification and function using a clinically important cell type as a model.
Summary
Vertebrates contain hundreds of different cell types which maintain phenotypic identity by a combination of epigenetic programming and genomic regulation. Systems biology approaches are now used in a number of laboratories to determine how transcription factors and chromatin marks pattern the human genome. Despite high conservation of the cellular and molecular function of many mammalian transcription factors, our recent experiments in matched mouse and human tissues indicates that most transcription factor binding events to DNA are very poorly conserved. A hypothesis that could account for this apparent divergence is that the larger regional pattern of transcription factor binding may be conserved. To test this, (1) we are characterizing the global transcriptional profile, chromatin state, and complete genomic occupancy of a set of tissue-specific transcription factors in hepatocytes of strategically chosen mammals; (2) to further identify the precise mechanistic contribution of cis and trans effects, we are comparing transcription factor binding at homologous regions of human and mouse DNA in a mouse line that carries human chromosome 21. Together, these projects will provide insight into the general principles of how transcriptional networks are evolutionarily conserved to regulate cell fate specification and function using a clinically important cell type as a model.
Max ERC Funding
960 000 €
Duration
Start date: 2008-10-01, End date: 2013-09-30
Project acronym DESTABLE
Project Destabilisation of sociotechnical regimes as the key to transitions towards sustainability
Researcher (PI) Frank Geels
Host Institution (HI) THE UNIVERSITY OF SUSSEX
Call Details Starting Grant (StG), SH2, ERC-2007-StG
Summary Sociotechnical transitions are important to address environmental problems. The present literature focuses on green options that break through and replace existing sociotechnical regimes. The project turns the analytical focus upside down, seeing the destabilisation and decline of existing regimes as the key to transitions. Regimes refer to the rules (knowledge base, belief system, mission, strategic orientation) shared by incumbent actors in an industry. Destabilisation results from increasing external pressures (economic, normative, regulatory) and eroding commitment of actors to regime rules. Research questions are: 1 To what degree have regimes in transport, energy and agriculture destabilised in the last 30 years, as a result of environmental pressures? 2 What kind of process is regime destabilisation and how should it be conceptualised for environmental problems? Which mechanisms are important and how do they interact? The project develops a theoretical perspective, combining insights from neo-institutional theory, STS, evolutionary economics. A phase-based pattern and three propositions are advanced. To investigate destabilisation, the project uses case studies as research strategy, which is appropriate for tracing complex processes such as changing beliefs and identities, fuzzy network boundaries, and many interacting (external) factors. Two PhD projects do four longitudinal case studies about destabilisation. Cases are selected with regard to the phase-based pattern and propositions. One case (decline of domestic coal) went though all phases. Another case (destabilisation of pig farming) has progressed far into the last phase. Coal in electricity and the car regime are less far in the phase-pattern, and probably less destabilised. The PI integrates findings from PhD projects, providing general answers to research questions. He also elaborates the inter-disciplinary perspective, and addresses the possibilities for sustainability transitions.
Summary
Sociotechnical transitions are important to address environmental problems. The present literature focuses on green options that break through and replace existing sociotechnical regimes. The project turns the analytical focus upside down, seeing the destabilisation and decline of existing regimes as the key to transitions. Regimes refer to the rules (knowledge base, belief system, mission, strategic orientation) shared by incumbent actors in an industry. Destabilisation results from increasing external pressures (economic, normative, regulatory) and eroding commitment of actors to regime rules. Research questions are: 1 To what degree have regimes in transport, energy and agriculture destabilised in the last 30 years, as a result of environmental pressures? 2 What kind of process is regime destabilisation and how should it be conceptualised for environmental problems? Which mechanisms are important and how do they interact? The project develops a theoretical perspective, combining insights from neo-institutional theory, STS, evolutionary economics. A phase-based pattern and three propositions are advanced. To investigate destabilisation, the project uses case studies as research strategy, which is appropriate for tracing complex processes such as changing beliefs and identities, fuzzy network boundaries, and many interacting (external) factors. Two PhD projects do four longitudinal case studies about destabilisation. Cases are selected with regard to the phase-based pattern and propositions. One case (decline of domestic coal) went though all phases. Another case (destabilisation of pig farming) has progressed far into the last phase. Coal in electricity and the car regime are less far in the phase-pattern, and probably less destabilised. The PI integrates findings from PhD projects, providing general answers to research questions. He also elaborates the inter-disciplinary perspective, and addresses the possibilities for sustainability transitions.
Max ERC Funding
907 114 €
Duration
Start date: 2008-09-01, End date: 2012-11-30
Project acronym dynamicmodifications
Project Complexity and dynamics of nucleic acids modifications in vivo
Researcher (PI) Petra Hajkova
Host Institution (HI) IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Call Details Consolidator Grant (CoG), LS2, ERC-2014-CoG
Summary Development of any organism starts with a totipotent cell (zygote). Through series of cell divisions and differentiation processes this cell will eventually give rise to the whole organism containing hundreds of specialised cell. While the cells at the onset of development have the capacity to generate all cell types (ie are toti-or pluripotent), this developmental capacity is progressively lost as the cells undertake cell fate decisions. At the molecular level, the memory of these events is laid down in a complex layer of epigenetic modifications at both the DNA and the chromatin level. Unidirectional character of the developmental progress dictates that the key acquired epigenetic modifications are stable and inherited through subsequent cell divisions. This paradigm is, however, challenged during cellular reprogramming that requires de-differentiation (nuclear transfer, induced pluripotent stem cells, wound healing and regeneration in lower organisms) or a change in cell fate (transdifferentiation). Despite intense efforts of numerous research teams, the molecular mechanisms of these processes remain enigmatic.
In order to understand cellular reprogramming at the molecular level, this proposal takes advantage of epigenetic reprogramming processes that occur naturally during mouse development. By using mouse fertilised zygote and mouse developing primordial germ cells we will investigate novel molecular components implicated in the genome-wide erasure of DNA methylation. Additionally, by using a unique combination of the developmental models with the state of the art ultra-sensitive LC/MS and genomics approaches we propose to investigate the dynamics and the interplay between DNA and RNA modifications during these key periods of embryonic development characterised by genome-wide epigenetic changes . Our work will thus provide new fundamental insights into a complex dynamics and interactions between epigenetic modifications that underlie epigenetic reprogramming
Summary
Development of any organism starts with a totipotent cell (zygote). Through series of cell divisions and differentiation processes this cell will eventually give rise to the whole organism containing hundreds of specialised cell. While the cells at the onset of development have the capacity to generate all cell types (ie are toti-or pluripotent), this developmental capacity is progressively lost as the cells undertake cell fate decisions. At the molecular level, the memory of these events is laid down in a complex layer of epigenetic modifications at both the DNA and the chromatin level. Unidirectional character of the developmental progress dictates that the key acquired epigenetic modifications are stable and inherited through subsequent cell divisions. This paradigm is, however, challenged during cellular reprogramming that requires de-differentiation (nuclear transfer, induced pluripotent stem cells, wound healing and regeneration in lower organisms) or a change in cell fate (transdifferentiation). Despite intense efforts of numerous research teams, the molecular mechanisms of these processes remain enigmatic.
In order to understand cellular reprogramming at the molecular level, this proposal takes advantage of epigenetic reprogramming processes that occur naturally during mouse development. By using mouse fertilised zygote and mouse developing primordial germ cells we will investigate novel molecular components implicated in the genome-wide erasure of DNA methylation. Additionally, by using a unique combination of the developmental models with the state of the art ultra-sensitive LC/MS and genomics approaches we propose to investigate the dynamics and the interplay between DNA and RNA modifications during these key periods of embryonic development characterised by genome-wide epigenetic changes . Our work will thus provide new fundamental insights into a complex dynamics and interactions between epigenetic modifications that underlie epigenetic reprogramming
Max ERC Funding
2 000 000 €
Duration
Start date: 2015-08-01, End date: 2020-07-31
Project acronym EUCONRES
Project A European Approach to Conflict Resolution? Institutional Learning and the ESDP
Researcher (PI) Michael Smith
Host Institution (HI) THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
Call Details Starting Grant (StG), SH2, ERC-2007-StG
Summary To what extent can international institutions learn? What factors determine whether such institutions develop capacities for self-awareness and endogenous institutional change? This project investigates these questions in the context of the European Union (EU). Specifically, it examines the dramatic expansion in security missions led by the EU since 2003, a capacity that many observers doubted was even possible for the EU. To explain this change in institutional behaviour, the project intends to develop a theory of institutional learning to analyze the EU’s instigation and implementation of 16 security operations in various regions under the auspices of the European Security and Defence Policy (ESDP). In addition, with these missions the EU has shown a growing capacity to innovate in security affairs, using a unique civilian crisis management (CCM) capacity linked to security sector reform and other EU policy tools, including the ESDP, the Common Foreign and Security Policy (CFSP), and the European Neighbourhood Policy (ENP). These changes demand further examination in light of not only the growing ambitions of the EU itself but also in terms of the increasing demands for security assistance placed on a variety of IOs, such as the UN, NATO, and the OSCE. The initial phase of the project will focus on four key ESDP operations as detailed case studies – Macedonia, the Palestinian Authority, the Democratic Republic of the Congo, and Bosnia-Hercegovina – to explain this innovation. Following the investigation of these representative cases, the later stages of the project will examine more recent EU security operations in hopes of developing a general theory of EU institutional learning in the area of foreign/security/defence policy. The project also hopes to generalize beyond this theory to other EU policy domains and, potentially, other IOs at the regional and global levels. In doing so the findings could have major implications for global governance.
Summary
To what extent can international institutions learn? What factors determine whether such institutions develop capacities for self-awareness and endogenous institutional change? This project investigates these questions in the context of the European Union (EU). Specifically, it examines the dramatic expansion in security missions led by the EU since 2003, a capacity that many observers doubted was even possible for the EU. To explain this change in institutional behaviour, the project intends to develop a theory of institutional learning to analyze the EU’s instigation and implementation of 16 security operations in various regions under the auspices of the European Security and Defence Policy (ESDP). In addition, with these missions the EU has shown a growing capacity to innovate in security affairs, using a unique civilian crisis management (CCM) capacity linked to security sector reform and other EU policy tools, including the ESDP, the Common Foreign and Security Policy (CFSP), and the European Neighbourhood Policy (ENP). These changes demand further examination in light of not only the growing ambitions of the EU itself but also in terms of the increasing demands for security assistance placed on a variety of IOs, such as the UN, NATO, and the OSCE. The initial phase of the project will focus on four key ESDP operations as detailed case studies – Macedonia, the Palestinian Authority, the Democratic Republic of the Congo, and Bosnia-Hercegovina – to explain this innovation. Following the investigation of these representative cases, the later stages of the project will examine more recent EU security operations in hopes of developing a general theory of EU institutional learning in the area of foreign/security/defence policy. The project also hopes to generalize beyond this theory to other EU policy domains and, potentially, other IOs at the regional and global levels. In doing so the findings could have major implications for global governance.
Max ERC Funding
1 019 264 €
Duration
Start date: 2008-05-01, End date: 2013-04-30
Project acronym EUDEMOS
Project Constrained Democracy: Citizens’ Responses to Limited Political Choice in the European Union
Researcher (PI) Sara Binzer Hobolt
Host Institution (HI) LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE
Call Details Consolidator Grant (CoG), SH2, ERC-2014-CoG
Summary National governments operate under the growing constraints of European integration that limit the choices they can offer citizens and the policy instruments they can use. Yet, despite the centrality of political choice to the functioning of electoral democracy, we know very little about the consequences of constrained political choices for citizens’ engagement in democratic processes. Across Europe, an increasing number of citizens are supporting extreme parties or declining to take part in democratic elections. This project offers the first systematic examination of how the range and substance of political choices offered to citizens in the EU shape democratic perceptions and electoral behaviour. Understanding how citizens perceive and react to the growing constraints on domestic politics is crucial to a diagnosis of European democracy and for an evidence-based debate on reform of EU institutions. Building on the Principal Investigator’s award-winning research on electoral democracy and extensive experience of designing and analysing cross-national surveys and experiments, this project is a pioneering study of the consequences of constrained democracy. It uniquely combines a large-N cross-national analysis of citizens’ responses to mainstream party convergence and case studies of the ‘emergency politics’ of the Eurozone crisis with micro-level experimental work. This project aims to transform the study of citizens’ democratic attitudes and behaviour by focusing on the importance of political choice. By developing and testing a theoretical model of heterogeneous citizen responses to the constrained political choice, the project provides insights into why citizens turn against mainstream parties or exit democratic processes altogether. This further allows EUDEMOS to develop proposals for how institutions can be designed to facilitate citizens’ participation in and satisfaction with democratic processes in a multi-level European Union.
Summary
National governments operate under the growing constraints of European integration that limit the choices they can offer citizens and the policy instruments they can use. Yet, despite the centrality of political choice to the functioning of electoral democracy, we know very little about the consequences of constrained political choices for citizens’ engagement in democratic processes. Across Europe, an increasing number of citizens are supporting extreme parties or declining to take part in democratic elections. This project offers the first systematic examination of how the range and substance of political choices offered to citizens in the EU shape democratic perceptions and electoral behaviour. Understanding how citizens perceive and react to the growing constraints on domestic politics is crucial to a diagnosis of European democracy and for an evidence-based debate on reform of EU institutions. Building on the Principal Investigator’s award-winning research on electoral democracy and extensive experience of designing and analysing cross-national surveys and experiments, this project is a pioneering study of the consequences of constrained democracy. It uniquely combines a large-N cross-national analysis of citizens’ responses to mainstream party convergence and case studies of the ‘emergency politics’ of the Eurozone crisis with micro-level experimental work. This project aims to transform the study of citizens’ democratic attitudes and behaviour by focusing on the importance of political choice. By developing and testing a theoretical model of heterogeneous citizen responses to the constrained political choice, the project provides insights into why citizens turn against mainstream parties or exit democratic processes altogether. This further allows EUDEMOS to develop proposals for how institutions can be designed to facilitate citizens’ participation in and satisfaction with democratic processes in a multi-level European Union.
Max ERC Funding
1 508 822 €
Duration
Start date: 2015-09-01, End date: 2021-01-31
Project acronym EvoGenMed
Project Evolutionary genomics: new perspectives and novel medical applications
Researcher (PI) Laurence Hurst
Host Institution (HI) UNIVERSITY OF BATH
Call Details Advanced Grant (AdG), LS8, ERC-2014-ADG
Summary To make for better diagnostics and safer applications of genomics we need a better understanding of our genome and how it functions. Until recently we thought we knew: intergenic sequence must be largely “junk” and mutations that, for example, affect genes but not the protein (synonymous mutations) must be effectively neutral. This degenerate genome view accords with the nearly-neutral theory’s prediction that selection will be weaker when populations are small. But is this all there is to it? I shall investigate two new interrelated perspectives on genome evolution. First, I suggest that to mitigate errors, owing to our high error rates, our genome can be under stronger, not weaker, selection. Second, that errors might be a source of evolutionary novelty. Error mitigation, my team has shown, often involves selection on seemingly innocuous mutations such as synonymous changes. Remarkably, we discovered that selection to ensure error-proof splicing is possibly more prevalent on synonymous mutations when populations are small, making seemingly innocuous mutations stronger candidates for human diseases. I shall provide the first test of the new error-proofing perspective through comparative genomic analysis on synonymous site evolution. To investigate error as a source of novelty I shall consider whether expression piggy-backing (expression of a gene affecting its neighbors) forces rewiring of gene networks. Importantly, I shall translate our new understanding to enable better diagnostics and improved therapeutics. I shall develop a much-needed computer package to identify candidate disease-causing synonymous changes. In addition, knowing how synonymous sites modulate splicing will allow me to design better intronless transgenes. Transgenes must also be inserted in genomic regions immune to piggy-backing. I will examine transposable element related piggy-backing to characterize “safe” sites for therapeutic gene insertion and mammalian transgenesis more generally.
Summary
To make for better diagnostics and safer applications of genomics we need a better understanding of our genome and how it functions. Until recently we thought we knew: intergenic sequence must be largely “junk” and mutations that, for example, affect genes but not the protein (synonymous mutations) must be effectively neutral. This degenerate genome view accords with the nearly-neutral theory’s prediction that selection will be weaker when populations are small. But is this all there is to it? I shall investigate two new interrelated perspectives on genome evolution. First, I suggest that to mitigate errors, owing to our high error rates, our genome can be under stronger, not weaker, selection. Second, that errors might be a source of evolutionary novelty. Error mitigation, my team has shown, often involves selection on seemingly innocuous mutations such as synonymous changes. Remarkably, we discovered that selection to ensure error-proof splicing is possibly more prevalent on synonymous mutations when populations are small, making seemingly innocuous mutations stronger candidates for human diseases. I shall provide the first test of the new error-proofing perspective through comparative genomic analysis on synonymous site evolution. To investigate error as a source of novelty I shall consider whether expression piggy-backing (expression of a gene affecting its neighbors) forces rewiring of gene networks. Importantly, I shall translate our new understanding to enable better diagnostics and improved therapeutics. I shall develop a much-needed computer package to identify candidate disease-causing synonymous changes. In addition, knowing how synonymous sites modulate splicing will allow me to design better intronless transgenes. Transgenes must also be inserted in genomic regions immune to piggy-backing. I will examine transposable element related piggy-backing to characterize “safe” sites for therapeutic gene insertion and mammalian transgenesis more generally.
Max ERC Funding
2 497 996 €
Duration
Start date: 2016-01-01, End date: 2020-12-31
Project acronym EVOLHGT
Project Selective Barriers to Horizontal Gene Transfer
Researcher (PI) Jonathan Paul Bollback
Host Institution (HI) THE UNIVERSITY OF LIVERPOOL
Call Details Consolidator Grant (CoG), LS8, ERC-2014-CoG
Summary Horizontal gene transfer (HGT) is a form of genic inheritance that occurs between individuals in a population or between species rather than from parent to offspring. HGT is most prevalent in bacteria, where it is an important source of novel metabolic pathways, pathogenicity factors, and antibiotic resistance.
In spite of the importance of HGT, we understand little about the evolutionary barriers to HGT. This proposal will outline a systematic experimental approach to elucidate factors that select for or against horizontally transferred genes, by pursuing three objectives. The first is to quantify intrinsic selection acting on newly transferred genes, by experimentally transferring and expressing several hundred genes across species boundaries. We will be able to systematically classify genes as resistant or permissive to transfer, examine the effect of the function and position in metabolic and regulatory networks on resistance to transfer, as well as identify any genes with substantial intrinsic benefits. The second objective is to examine the effect of evolutionary divergence on HGT, by determining whether genes from closely related species are more permissive to transfer than those from more divergent species. The final objective is to determine the role of the environment in shaping these selective effects. Understanding how robust the selective effects are to different environmental conditions will aid in evaluating the relative roles of genetics and the environment as factors in the evolutionary outcomes of HGT . Overall, this work will provide a systematic analysis of the roles of different factors in affecting the outcomes of horizontal gene transfer. Understanding this process in a quantitative fashion is critical to understanding bacterial adaptation and diversity.
Summary
Horizontal gene transfer (HGT) is a form of genic inheritance that occurs between individuals in a population or between species rather than from parent to offspring. HGT is most prevalent in bacteria, where it is an important source of novel metabolic pathways, pathogenicity factors, and antibiotic resistance.
In spite of the importance of HGT, we understand little about the evolutionary barriers to HGT. This proposal will outline a systematic experimental approach to elucidate factors that select for or against horizontally transferred genes, by pursuing three objectives. The first is to quantify intrinsic selection acting on newly transferred genes, by experimentally transferring and expressing several hundred genes across species boundaries. We will be able to systematically classify genes as resistant or permissive to transfer, examine the effect of the function and position in metabolic and regulatory networks on resistance to transfer, as well as identify any genes with substantial intrinsic benefits. The second objective is to examine the effect of evolutionary divergence on HGT, by determining whether genes from closely related species are more permissive to transfer than those from more divergent species. The final objective is to determine the role of the environment in shaping these selective effects. Understanding how robust the selective effects are to different environmental conditions will aid in evaluating the relative roles of genetics and the environment as factors in the evolutionary outcomes of HGT . Overall, this work will provide a systematic analysis of the roles of different factors in affecting the outcomes of horizontal gene transfer. Understanding this process in a quantitative fashion is critical to understanding bacterial adaptation and diversity.
Max ERC Funding
1 820 865 €
Duration
Start date: 2015-06-01, End date: 2020-05-31
Project acronym FINGOVEU
Project Financial Services Governance in the European Union
Researcher (PI) Lucia Quaglia
Host Institution (HI) THE UNIVERSITY OF SUSSEX
Call Details Starting Grant (StG), SH2, ERC-2007-StG
Summary This project examines the governance of financial services in the European Union (EU). This research is both academically interesting and policy relevant. Academic research has not kept pace with new developments in this field, and interdisciplinary research is very much needed, as financial services governance is at the cross road between politics, economics and law. At the practical level, the financial sector is a core part of national economies and one of the most active areas of EU policy making. Moreover, this research will contribute to informing the public discussion in a policy area that is often perceived as 'technical', which tends to limit the public scrutiny of it. For the purposes of this research, the governance of financial services in the EU includes: i) the institutional framework through which policies are made; ii) regulation, which is comprised of market-making and market-framing measures; and iii) supervision, that is: the monitoring and enforcement of regulation as well as the practical cooperation between supervisory authorities. First, the project will map the complex institutional framework underpinning financial services governance in the EU, explaining how such framework interplays with regulatory and supervisory arrangements in international arenas and in selected countries. Second, through competitive hypotheses testing, the project will analyse the EU policy-making processes in the financial sector: the main policy-makers and stakeholders involved; their resources, relationships and influence on the policy process; and the outcome. Besides contributing to the policy-oriented debate on financial services regulation and supervision in the EU, the ultimate theoretical goal of the research is to devise an integrated analytical framework that by combining various theoretical approaches and identifying their scope conditions could account for financial services governance in the EU, advancing theories of EU policy making.
Summary
This project examines the governance of financial services in the European Union (EU). This research is both academically interesting and policy relevant. Academic research has not kept pace with new developments in this field, and interdisciplinary research is very much needed, as financial services governance is at the cross road between politics, economics and law. At the practical level, the financial sector is a core part of national economies and one of the most active areas of EU policy making. Moreover, this research will contribute to informing the public discussion in a policy area that is often perceived as 'technical', which tends to limit the public scrutiny of it. For the purposes of this research, the governance of financial services in the EU includes: i) the institutional framework through which policies are made; ii) regulation, which is comprised of market-making and market-framing measures; and iii) supervision, that is: the monitoring and enforcement of regulation as well as the practical cooperation between supervisory authorities. First, the project will map the complex institutional framework underpinning financial services governance in the EU, explaining how such framework interplays with regulatory and supervisory arrangements in international arenas and in selected countries. Second, through competitive hypotheses testing, the project will analyse the EU policy-making processes in the financial sector: the main policy-makers and stakeholders involved; their resources, relationships and influence on the policy process; and the outcome. Besides contributing to the policy-oriented debate on financial services regulation and supervision in the EU, the ultimate theoretical goal of the research is to devise an integrated analytical framework that by combining various theoretical approaches and identifying their scope conditions could account for financial services governance in the EU, advancing theories of EU policy making.
Max ERC Funding
377 464 €
Duration
Start date: 2008-10-01, End date: 2012-03-31
Project acronym FORESIGHT
Project Do Forecasts Matter? Early Warnings and the Prevention of Armed Conflict
Researcher (PI) Christoph Meyer
Host Institution (HI) KING'S COLLEGE LONDON
Call Details Starting Grant (StG), SH2, ERC-2007-StG
Summary What impact do forecasts have on political action? How are they communicated, perceived and used in order to prevent harmful events in the future? There are few policy areas as dependent on good forecasts as efforts aimed at preventing intra-state violent conflicts. Both practitioners and scholars agree that early, appropriate and sustained action on the part of various international players can help to avoid or at least alleviate many of the harmful consequences. Preventing the outbreak of such conflicts has increasingly become a priority objective of the European Union and its most influential member states. But there is a curious gap in the literature with respect to the exact linkage between early warning and political response: under what conditions do forecasts of impending conflicts lead to political action? The first objective of the project is to better understand the interplay of communication and political perception of early warnings about impending intra-state armed conflict. In a second step, the project will compare the findings about early warnings regarding armed conflict to insights about the impact of forecasts in other policy-areas such as adjusting to impending environmental and economic crises. Thus, the project aims to contribute to improving public policy by analysing the interplay of forecasting, advocacy and preventive decision-making.
Summary
What impact do forecasts have on political action? How are they communicated, perceived and used in order to prevent harmful events in the future? There are few policy areas as dependent on good forecasts as efforts aimed at preventing intra-state violent conflicts. Both practitioners and scholars agree that early, appropriate and sustained action on the part of various international players can help to avoid or at least alleviate many of the harmful consequences. Preventing the outbreak of such conflicts has increasingly become a priority objective of the European Union and its most influential member states. But there is a curious gap in the literature with respect to the exact linkage between early warning and political response: under what conditions do forecasts of impending conflicts lead to political action? The first objective of the project is to better understand the interplay of communication and political perception of early warnings about impending intra-state armed conflict. In a second step, the project will compare the findings about early warnings regarding armed conflict to insights about the impact of forecasts in other policy-areas such as adjusting to impending environmental and economic crises. Thus, the project aims to contribute to improving public policy by analysing the interplay of forecasting, advocacy and preventive decision-making.
Max ERC Funding
754 077 €
Duration
Start date: 2008-09-01, End date: 2011-10-31
Project acronym GREYZONE
Project Illuminating the 'Grey Zone': Addressing Complex Complicity in Human Rights Violations
Researcher (PI) Mihaela Mihai
Host Institution (HI) THE UNIVERSITY OF EDINBURGH
Call Details Starting Grant (StG), SH2, ERC-2014-STG
Summary The grey zone of bystanders, collaborators and beneficiaries of violence escapes the scope of main Transitional Justice (TJ) institutions and poses tough questions for scholars and architects of post-conflict societies. This interdisciplinary project shifts the focus of academic and political debates by pursuing three objectives: conceptually, it departs from the dominant victim-perpetrator paradigm and theorises the many faces in the grey zone by analysing the interplay between structure and agency; normatively, it argues that no account of TJ is complete without engaging the grey zone; empirically, it tests if, in tackling the grey zone, cinematographic and literary representations can supplement typical TJ mechanisms (trials, truth commissions, lustration). Four cases are analysed: authoritarianism plus military occupation (Vichy France), apartheid (South Africa), totalitarianism (Romania 1945–1989) and military dictatorship (Argentina 1976–1983). The cases provide a variety of contexts of complicity and feature the most frequently used TJ mechanisms. They serve to a) examine the relationship between the official story emerging from state-orchestrated TJ mechanisms and artistic narratives of complicity; b) contextually distinguish disclosive from obscuring artistic representations of the grey zone; c) explore the contribution of these representations to TJ efforts by studying their effect on public debates about—and institutional responses to—the past. Working at the frontiers between political science, philosophy, history, law, literature and cinema, this pioneering project has critical and institutional impact. Critically, it discloses the limits of current TJ theory and practice by emphasising the negative political effects of ignoring general complicity in violence. Institutionally, it seeks to enrich the toolkit of scholars and practitioners by pointing to the potential use of cinema and literature in civic education aimed at deterrence and reconciliation.
Summary
The grey zone of bystanders, collaborators and beneficiaries of violence escapes the scope of main Transitional Justice (TJ) institutions and poses tough questions for scholars and architects of post-conflict societies. This interdisciplinary project shifts the focus of academic and political debates by pursuing three objectives: conceptually, it departs from the dominant victim-perpetrator paradigm and theorises the many faces in the grey zone by analysing the interplay between structure and agency; normatively, it argues that no account of TJ is complete without engaging the grey zone; empirically, it tests if, in tackling the grey zone, cinematographic and literary representations can supplement typical TJ mechanisms (trials, truth commissions, lustration). Four cases are analysed: authoritarianism plus military occupation (Vichy France), apartheid (South Africa), totalitarianism (Romania 1945–1989) and military dictatorship (Argentina 1976–1983). The cases provide a variety of contexts of complicity and feature the most frequently used TJ mechanisms. They serve to a) examine the relationship between the official story emerging from state-orchestrated TJ mechanisms and artistic narratives of complicity; b) contextually distinguish disclosive from obscuring artistic representations of the grey zone; c) explore the contribution of these representations to TJ efforts by studying their effect on public debates about—and institutional responses to—the past. Working at the frontiers between political science, philosophy, history, law, literature and cinema, this pioneering project has critical and institutional impact. Critically, it discloses the limits of current TJ theory and practice by emphasising the negative political effects of ignoring general complicity in violence. Institutionally, it seeks to enrich the toolkit of scholars and practitioners by pointing to the potential use of cinema and literature in civic education aimed at deterrence and reconciliation.
Max ERC Funding
1 349 481 €
Duration
Start date: 2015-09-01, End date: 2020-02-29
Project acronym HERITAGE
Project Cultural Heritage and Economic Development in International and European Law
Researcher (PI) Valentina Vadi
Host Institution (HI) UNIVERSITY OF LANCASTER
Call Details Starting Grant (StG), SH2, ERC-2014-STG
Summary Can states promote economic development without infringing upon their cultural heritage? Although economic globalization and international economic governance have spurred a more intense dialogue and interaction among nations - potentially promoting cultural diversity and providing the funds to recover and preserve cultural heritage - these phenomena can also jeopardize the cultural wealth of nations. Trade in cultural products can lead to cultural homogenization and even to cultural hegemony. In parallel, foreign direct investments have an unmatched penetrating force with the ultimate capacity of changing landscapes and erasing memory. At the same time, the increase in global trade, economic integration and foreign direct investment has determined the creation of legally binding and highly effective regimes that demand states to promote and facilitate trade and foreign direct investment. Has an international economic culture emerged that emphasizes productivity and economic development at the expense of cultural wealth? Does the existing legal framework adequately protect the cultural wealth of nations vis-à-vis economic globalization? Could existing mechanisms in international and European law constrain negative effects of globalization?
HERITAGE aims to map the interaction between economic globalization and each specimen of cultural heritage - world heritage, cultural diversity, intangible cultural heritage, indigenous heritage and underwater cultural heritage - in international and European law by investigating the relevant case law before international courts and tribunals. The study adopts an interdisciplinary approach; the relevant cases will be investigated in consideration of both their legal and cultural relevance. The main outcome of this research project will be a monograph written by the principal investigator to be published by a major international publisher; and a number of articles to be published in major international journals.
Summary
Can states promote economic development without infringing upon their cultural heritage? Although economic globalization and international economic governance have spurred a more intense dialogue and interaction among nations - potentially promoting cultural diversity and providing the funds to recover and preserve cultural heritage - these phenomena can also jeopardize the cultural wealth of nations. Trade in cultural products can lead to cultural homogenization and even to cultural hegemony. In parallel, foreign direct investments have an unmatched penetrating force with the ultimate capacity of changing landscapes and erasing memory. At the same time, the increase in global trade, economic integration and foreign direct investment has determined the creation of legally binding and highly effective regimes that demand states to promote and facilitate trade and foreign direct investment. Has an international economic culture emerged that emphasizes productivity and economic development at the expense of cultural wealth? Does the existing legal framework adequately protect the cultural wealth of nations vis-à-vis economic globalization? Could existing mechanisms in international and European law constrain negative effects of globalization?
HERITAGE aims to map the interaction between economic globalization and each specimen of cultural heritage - world heritage, cultural diversity, intangible cultural heritage, indigenous heritage and underwater cultural heritage - in international and European law by investigating the relevant case law before international courts and tribunals. The study adopts an interdisciplinary approach; the relevant cases will be investigated in consideration of both their legal and cultural relevance. The main outcome of this research project will be a monograph written by the principal investigator to be published by a major international publisher; and a number of articles to be published in major international journals.
Max ERC Funding
485 138 €
Duration
Start date: 2015-05-01, End date: 2018-08-31
Project acronym iLABOUR
Project Online Labour: The Construction of Labour Markets, Institutions and Movements on the Internet
Researcher (PI) Vili Anton Lehdonvirta
Host Institution (HI) THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Call Details Starting Grant (StG), SH2, ERC-2014-STG
Summary "World Bank, EC Joint Research Centre, and other bodies have recently highlighted the potential of online labour markets to boost employment and economic growth. While national job markets have stagnated, online labour markets that connect firms with knowledge and service workers around the world have grown up to 60% a year.
An overlooked aspect of these markets is that they extricate workers and employers from national institutional frameworks, such as employment law and collective bargaining, and instead impose their own, technologically enforced institutions. For example, a leading marketplace recently instated a global minimum wage of 4.00 USD/h. With over 540,000 employers and 4,000,000 registered workers in 180 countries, this Californian company is making critical labour policy decisions that influence businesses and individuals from Berlin to Manila.
The objective of this project is to lay bare the politics and institutions of these next-generation labour markets promoted with discourses of technological progress. Whose interests find expression in their institutions? Some online workers have begun to organize transnationally with the help of digital media. How do online labour movements emerge and assert power on these markets? And finally, to what extent are these relations still reducible to struggles between capital and labour, rather than more ambiguous networked models of production?
We will tackle these questions through a combination of conventional social research methods and innovative Internet research methods, on both virtual research sites (online labour markets and workers' online communities) and physical research sites (market operators' premises and worker gatherings). We survey, interview, and observe designers and workers to reconstruct processes through which online markets, institutions, and movements are shaped, and ""scrape"" online data to quantify their influence. The results will open up important new vistas in labour policy debate."
Summary
"World Bank, EC Joint Research Centre, and other bodies have recently highlighted the potential of online labour markets to boost employment and economic growth. While national job markets have stagnated, online labour markets that connect firms with knowledge and service workers around the world have grown up to 60% a year.
An overlooked aspect of these markets is that they extricate workers and employers from national institutional frameworks, such as employment law and collective bargaining, and instead impose their own, technologically enforced institutions. For example, a leading marketplace recently instated a global minimum wage of 4.00 USD/h. With over 540,000 employers and 4,000,000 registered workers in 180 countries, this Californian company is making critical labour policy decisions that influence businesses and individuals from Berlin to Manila.
The objective of this project is to lay bare the politics and institutions of these next-generation labour markets promoted with discourses of technological progress. Whose interests find expression in their institutions? Some online workers have begun to organize transnationally with the help of digital media. How do online labour movements emerge and assert power on these markets? And finally, to what extent are these relations still reducible to struggles between capital and labour, rather than more ambiguous networked models of production?
We will tackle these questions through a combination of conventional social research methods and innovative Internet research methods, on both virtual research sites (online labour markets and workers' online communities) and physical research sites (market operators' premises and worker gatherings). We survey, interview, and observe designers and workers to reconstruct processes through which online markets, institutions, and movements are shaped, and ""scrape"" online data to quantify their influence. The results will open up important new vistas in labour policy debate."
Max ERC Funding
1 499 911 €
Duration
Start date: 2015-09-01, End date: 2020-08-31
Project acronym Intimacy
Project Doing Intimacy: A Multi-sited Ethnography of Modern Chinese Family Life
Researcher (PI) Jieyu Liu
Host Institution (HI) SCHOOL OF ORIENTAL AND AFRICAN STUDIES ROYAL CHARTER
Call Details Starting Grant (StG), SH2, ERC-2014-STG
Summary Families in Western countries have received a great deal of attention from social scientists but there is less information on family life in other regions of the world. Given its growing rapidly in global influence, China represents a crucial region for sociological advancement and understanding. There have been profound changes in the Chinese family over the last century as a result of industrialization, urbanization, the influence of the West and the political interventions carried out by the Communist Party since 1949. Existing scholarship has shown how the structure and function of Chinese families have adapted to changing political and economic circumstances but little is known about the changes in intimate spheres of Chinese families. This project will approach the subject of modern Chinese family life from an unconventional angle, analysing it as a process of practices and experiences. By setting a new agenda that moves from structures of family relationships to the quality of relationships and through examining ‘doing intimacy’, this project will take a closer, fresher, critical look at the Chinese family dynamics as they are lived. Informed by the emerging literature on gender, intimacy and modernity, this project will examine intergenerational relations as well as gender and sexual relations in the family. Is there an intimate revolution taking place? How is ‘modernity’/’tradition’ closely linked with practices of intimacy? To what extent can doing intimacy be a site of empowerment/domination for women? What will the study of Chinese families tell us about agency and local/global change? Through a multi-sited ethnography (mainland China, Hong Kong and Taiwan), this study will also compare practices of intimacy in various sites and examine whether/how they are by-products of particular socio-cultural configurations. It will identify the extent to which changes in Chinese families mirror changes in the West and the factors that contribute to these changes.
Summary
Families in Western countries have received a great deal of attention from social scientists but there is less information on family life in other regions of the world. Given its growing rapidly in global influence, China represents a crucial region for sociological advancement and understanding. There have been profound changes in the Chinese family over the last century as a result of industrialization, urbanization, the influence of the West and the political interventions carried out by the Communist Party since 1949. Existing scholarship has shown how the structure and function of Chinese families have adapted to changing political and economic circumstances but little is known about the changes in intimate spheres of Chinese families. This project will approach the subject of modern Chinese family life from an unconventional angle, analysing it as a process of practices and experiences. By setting a new agenda that moves from structures of family relationships to the quality of relationships and through examining ‘doing intimacy’, this project will take a closer, fresher, critical look at the Chinese family dynamics as they are lived. Informed by the emerging literature on gender, intimacy and modernity, this project will examine intergenerational relations as well as gender and sexual relations in the family. Is there an intimate revolution taking place? How is ‘modernity’/’tradition’ closely linked with practices of intimacy? To what extent can doing intimacy be a site of empowerment/domination for women? What will the study of Chinese families tell us about agency and local/global change? Through a multi-sited ethnography (mainland China, Hong Kong and Taiwan), this study will also compare practices of intimacy in various sites and examine whether/how they are by-products of particular socio-cultural configurations. It will identify the extent to which changes in Chinese families mirror changes in the West and the factors that contribute to these changes.
Max ERC Funding
1 487 500 €
Duration
Start date: 2015-10-01, End date: 2020-09-30