Project acronym 3FLEX
Project Three-Component Fermi Gas Lattice Experiment
Researcher (PI) Selim Jochim
Host Institution (HI) RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Call Details Starting Grant (StG), PE2, ERC-2011-StG_20101014
Summary Understanding the many-body physics of strongly correlated systems has always been a major challenge for theoretical and experimental physics. The recent advances in the field of ultracold quantum gases have opened a completely new way to study such strongly correlated systems. It is now feasible to use ultracold gases as quantum simulators for such diverse systems such as the Hubbard model or the BCS-BEC crossover. The objective of this project is to study a three-component Fermi gas in an optical lattice, a system with rich many-body physics. With our experiments we aim to contribute to the understanding of exotic phases which are discussed in the context of QCD and condensed matter physics.
Summary
Understanding the many-body physics of strongly correlated systems has always been a major challenge for theoretical and experimental physics. The recent advances in the field of ultracold quantum gases have opened a completely new way to study such strongly correlated systems. It is now feasible to use ultracold gases as quantum simulators for such diverse systems such as the Hubbard model or the BCS-BEC crossover. The objective of this project is to study a three-component Fermi gas in an optical lattice, a system with rich many-body physics. With our experiments we aim to contribute to the understanding of exotic phases which are discussed in the context of QCD and condensed matter physics.
Max ERC Funding
1 469 040 €
Duration
Start date: 2011-08-01, End date: 2016-07-31
Project acronym ABACUS
Project Advancing Behavioral and Cognitive Understanding of Speech
Researcher (PI) Bart De Boer
Host Institution (HI) VRIJE UNIVERSITEIT BRUSSEL
Call Details Starting Grant (StG), SH4, ERC-2011-StG_20101124
Summary I intend to investigate what cognitive mechanisms give us combinatorial speech. Combinatorial speech is the ability to make new words using pre-existing speech sounds. Humans are the only apes that can do this, yet we do not know how our brains do it, nor how exactly we differ from other apes. Using new experimental techniques to study human behavior and new computational techniques to model human cognition, I will find out how we deal with combinatorial speech.
The experimental part will study individual and cultural learning. Experimental cultural learning is a new technique that simulates cultural evolution in the laboratory. Two types of cultural learning will be used: iterated learning, which simulates language transfer across generations, and social coordination, which simulates emergence of norms in a language community. Using the two types of cultural learning together with individual learning experiments will help to zero in, from three angles, on how humans deal with combinatorial speech. In addition it will make a methodological contribution by comparing the strengths and weaknesses of the three methods.
The computer modeling part will formalize hypotheses about how our brains deal with combinatorial speech. Two models will be built: a high-level model that will establish the basic algorithms with which combinatorial speech is learned and reproduced, and a neural model that will establish in more detail how the algorithms are implemented in the brain. In addition, the models, through increasing understanding of how humans deal with speech, will help bridge the performance gap between human and computer speech recognition.
The project will advance science in four ways: it will provide insight into how our unique ability for using combinatorial speech works, it will tell us how this is implemented in the brain, it will extend the novel methodology of experimental cultural learning and it will create new computer models for dealing with human speech.
Summary
I intend to investigate what cognitive mechanisms give us combinatorial speech. Combinatorial speech is the ability to make new words using pre-existing speech sounds. Humans are the only apes that can do this, yet we do not know how our brains do it, nor how exactly we differ from other apes. Using new experimental techniques to study human behavior and new computational techniques to model human cognition, I will find out how we deal with combinatorial speech.
The experimental part will study individual and cultural learning. Experimental cultural learning is a new technique that simulates cultural evolution in the laboratory. Two types of cultural learning will be used: iterated learning, which simulates language transfer across generations, and social coordination, which simulates emergence of norms in a language community. Using the two types of cultural learning together with individual learning experiments will help to zero in, from three angles, on how humans deal with combinatorial speech. In addition it will make a methodological contribution by comparing the strengths and weaknesses of the three methods.
The computer modeling part will formalize hypotheses about how our brains deal with combinatorial speech. Two models will be built: a high-level model that will establish the basic algorithms with which combinatorial speech is learned and reproduced, and a neural model that will establish in more detail how the algorithms are implemented in the brain. In addition, the models, through increasing understanding of how humans deal with speech, will help bridge the performance gap between human and computer speech recognition.
The project will advance science in four ways: it will provide insight into how our unique ability for using combinatorial speech works, it will tell us how this is implemented in the brain, it will extend the novel methodology of experimental cultural learning and it will create new computer models for dealing with human speech.
Max ERC Funding
1 276 620 €
Duration
Start date: 2012-02-01, End date: 2017-01-31
Project acronym ACTMECH
Project Emergent Active Mechanical Behaviour of the Actomyosin Cell Cortex
Researcher (PI) Stephan Wolfgang Grill
Host Institution (HI) TECHNISCHE UNIVERSITAET DRESDEN
Call Details Starting Grant (StG), LS3, ERC-2011-StG_20101109
Summary The cell cortex is a highly dynamic layer of crosslinked actin filaments and myosin molecular motors beneath the cell membrane. It plays a central role in large scale rearrangements that occur inside cells. Many molecular mechanisms contribute to cortex structure and dynamics. However, cell scale physical properties of the cortex are difficult to grasp. This is problematic because for large scale rearrangements inside a cell, such as coherent flow of the cell cortex, it is the cell scale emergent properties that are important for the realization of such events. I will investigate how the actomyosin cytoskeleton behaves at a coarse grained and cellular scale, and will study how this emergent active behaviour is influenced by molecular mechanisms. We will study the cell cortex in the one cell stage C. elegans embryo, which undergoes large scale cortical flow during polarization and cytokinesis. We will combine theory and experiment. We will characterize cortex structure and dynamics with biophysical techniques such as cortical laser ablation and quantitative photobleaching experiments. We will develop and employ novel theoretical approaches to describe the cell scale mechanical behaviour in terms of an active complex fluid. We will utilize genetic approaches to understand how these emergent mechanical properties are influenced by molecular activities. A central goal is to arrive at a coarse grained description of the cortex that can predict future dynamic behaviour from the past structure, which is conceptually similar to how weather forecasting is accomplished. To date, systematic approaches to link molecular scale physical mechanisms to those on cellular scales are missing. This work will open new opportunities for cell biological and cell biophysical research, by providing a methodological approach for bridging scales, for studying emergent and large-scale active mechanical behaviours and linking them to molecular mechanisms.
Summary
The cell cortex is a highly dynamic layer of crosslinked actin filaments and myosin molecular motors beneath the cell membrane. It plays a central role in large scale rearrangements that occur inside cells. Many molecular mechanisms contribute to cortex structure and dynamics. However, cell scale physical properties of the cortex are difficult to grasp. This is problematic because for large scale rearrangements inside a cell, such as coherent flow of the cell cortex, it is the cell scale emergent properties that are important for the realization of such events. I will investigate how the actomyosin cytoskeleton behaves at a coarse grained and cellular scale, and will study how this emergent active behaviour is influenced by molecular mechanisms. We will study the cell cortex in the one cell stage C. elegans embryo, which undergoes large scale cortical flow during polarization and cytokinesis. We will combine theory and experiment. We will characterize cortex structure and dynamics with biophysical techniques such as cortical laser ablation and quantitative photobleaching experiments. We will develop and employ novel theoretical approaches to describe the cell scale mechanical behaviour in terms of an active complex fluid. We will utilize genetic approaches to understand how these emergent mechanical properties are influenced by molecular activities. A central goal is to arrive at a coarse grained description of the cortex that can predict future dynamic behaviour from the past structure, which is conceptually similar to how weather forecasting is accomplished. To date, systematic approaches to link molecular scale physical mechanisms to those on cellular scales are missing. This work will open new opportunities for cell biological and cell biophysical research, by providing a methodological approach for bridging scales, for studying emergent and large-scale active mechanical behaviours and linking them to molecular mechanisms.
Max ERC Funding
1 500 000 €
Duration
Start date: 2011-12-01, End date: 2017-08-31
Project acronym ADDICTION
Project Beyond the Genetics of Addiction
Researcher (PI) Jacqueline Mignon Vink
Host Institution (HI) STICHTING KATHOLIEKE UNIVERSITEIT
Call Details Starting Grant (StG), SH4, ERC-2011-StG_20101124
Summary My proposal seeks to explain the complex interplay between genetic and environmental causes of individual variation in substance use and the risk for abuse. Substance use is common. Substances like nicotine and cannabis have well-known negative health consequences, while alcohol and caffeine use may be both beneficial and detrimental, depending on quantity and frequency of use. Twin studies (including my own) demonstrated that both heritable and environmental factors play a role.
My proposal on substance use (nicotine, alcohol, cannabis and caffeine) is organized around several key objectives: 1. To unravel the complex contribution of genetic and environmental factors to substance use by using extended twin family designs; 2. To identify and confirm genes and gene networks involved in substance use by using DNA-variant data; 3. To explore gene expression patterns with RNA data in substance users versus non-users; 4. To investigate biomarkers in substance users versus non-users using blood or urine; 5. To unravel relation between substance use and health by linking twin-family data to national medical databases.
To realize these aims I will use the extensive resources of the Netherlands Twin Register (NTR); including both the longitudinal phenotype database and the biological samples. I have been involved in data collection, coordination of data collection and analyzing NTR data since 1999. With my comprehensive experience in data collection, data analyses and my knowledge in the field of behavior genetics and addiction research I will be able to successfully lead this cutting-edge project. Additional data crucial for the project will be collected by my team. Large samples will be available for this study and state-of-the art methods will be used to analyze the data. All together, my project will offer powerful approaches to unravel the complex interaction between genetic and environmental causes of individual differences in substance use and the risk for abuse.
Summary
My proposal seeks to explain the complex interplay between genetic and environmental causes of individual variation in substance use and the risk for abuse. Substance use is common. Substances like nicotine and cannabis have well-known negative health consequences, while alcohol and caffeine use may be both beneficial and detrimental, depending on quantity and frequency of use. Twin studies (including my own) demonstrated that both heritable and environmental factors play a role.
My proposal on substance use (nicotine, alcohol, cannabis and caffeine) is organized around several key objectives: 1. To unravel the complex contribution of genetic and environmental factors to substance use by using extended twin family designs; 2. To identify and confirm genes and gene networks involved in substance use by using DNA-variant data; 3. To explore gene expression patterns with RNA data in substance users versus non-users; 4. To investigate biomarkers in substance users versus non-users using blood or urine; 5. To unravel relation between substance use and health by linking twin-family data to national medical databases.
To realize these aims I will use the extensive resources of the Netherlands Twin Register (NTR); including both the longitudinal phenotype database and the biological samples. I have been involved in data collection, coordination of data collection and analyzing NTR data since 1999. With my comprehensive experience in data collection, data analyses and my knowledge in the field of behavior genetics and addiction research I will be able to successfully lead this cutting-edge project. Additional data crucial for the project will be collected by my team. Large samples will be available for this study and state-of-the art methods will be used to analyze the data. All together, my project will offer powerful approaches to unravel the complex interaction between genetic and environmental causes of individual differences in substance use and the risk for abuse.
Max ERC Funding
1 491 964 €
Duration
Start date: 2011-12-01, End date: 2017-05-31
Project acronym ADULT
Project Analysis of the Dark Universe through Lensing Tomography
Researcher (PI) Hendrik Hoekstra
Host Institution (HI) UNIVERSITEIT LEIDEN
Call Details Starting Grant (StG), PE9, ERC-2011-StG_20101014
Summary The discoveries that the expansion of the universe is accelerating due to an unknown “dark energy”
and that most of the matter is invisible, highlight our lack of understanding of the major constituents
of the universe. These surprising findings set the stage for research in cosmology at the start of the
21st century. The objective of this proposal is to advance observational constraints to a level where we can distinguish between physical mechanisms that aim to explain the properties of dark energy and the observed distribution of dark matter throughout the universe. We use a relatively new technique called weak gravitational lensing: the accurate measurement of correlations in the orientations of distant galaxies enables us to map the dark matter distribution directly and to extract the cosmological information that is encoded by the large-scale structure.
To study the dark universe we will analyse data from a new state-of-the-art imaging survey: the Kilo-
Degree Survey (KiDS) will cover 1500 square degrees in 9 filters. The combination of its large survey
area and the availability of exquisite photometric redshifts for the sources makes KiDS the first
project that can place interesting constraints on the dark energy equation-of-state using lensing data
alone. Combined with complementary results from Planck, our measurements will provide one of the
best views of the dark side of the universe before much larger space-based projects commence.
To reach the desired accuracy we need to carefully measure the shapes of distant background galaxies. We also need to account for any intrinsic alignments that arise due to tidal interactions, rather than through lensing. Reducing these observational and physical biases to negligible levels is a necessarystep to ensure the success of KiDS and an important part of our preparation for more challenging projects such as the European-led space mission Euclid.
Summary
The discoveries that the expansion of the universe is accelerating due to an unknown “dark energy”
and that most of the matter is invisible, highlight our lack of understanding of the major constituents
of the universe. These surprising findings set the stage for research in cosmology at the start of the
21st century. The objective of this proposal is to advance observational constraints to a level where we can distinguish between physical mechanisms that aim to explain the properties of dark energy and the observed distribution of dark matter throughout the universe. We use a relatively new technique called weak gravitational lensing: the accurate measurement of correlations in the orientations of distant galaxies enables us to map the dark matter distribution directly and to extract the cosmological information that is encoded by the large-scale structure.
To study the dark universe we will analyse data from a new state-of-the-art imaging survey: the Kilo-
Degree Survey (KiDS) will cover 1500 square degrees in 9 filters. The combination of its large survey
area and the availability of exquisite photometric redshifts for the sources makes KiDS the first
project that can place interesting constraints on the dark energy equation-of-state using lensing data
alone. Combined with complementary results from Planck, our measurements will provide one of the
best views of the dark side of the universe before much larger space-based projects commence.
To reach the desired accuracy we need to carefully measure the shapes of distant background galaxies. We also need to account for any intrinsic alignments that arise due to tidal interactions, rather than through lensing. Reducing these observational and physical biases to negligible levels is a necessarystep to ensure the success of KiDS and an important part of our preparation for more challenging projects such as the European-led space mission Euclid.
Max ERC Funding
1 316 880 €
Duration
Start date: 2012-01-01, End date: 2016-12-31
Project acronym AMPRO
Project Advanced Electronic Materials and Devices through Novel Processing Paradigms
Researcher (PI) Thomas Anthopoulos
Host Institution (HI) IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Call Details Starting Grant (StG), PE5, ERC-2011-StG_20101014
Summary "I propose a structured multidisciplinary research programme that seeks to combine advanced materials, such as metal oxides and organics, with novel fabrication methods to develop devices for application in: (1) large area electronics, (2) integrated nanoelectronics and (3) sensors. At the heart of this programme lies the development of novel oxide semiconductors. These will be synthesised from solution using precursors. Chemical doping via physical blending will be explored for the tuning of the electronic properties of these compounds. This simple approach will enable the rapid development of a library of materials far beyond those accessible by traditional methods. Oxides will then be combined with inorganic/organic dielectrics to demonstrate low power transistors. Ultimate target for application area (1) is the development of transistors with hole/electron mobilities exceeding 20/200 cm^2/Vs respectively. For application area (2) I will combine the precursor formulations with advanced scanning thermochemical nanolithography. A heated atomic force microscope tip will be used for the local chemical conversion of the precursor to oxide with sub-50 nm resolution. This will enable patterning of nanostructures with desirable shape and size. Sequential patterning of semi/conductive layers combined with SAM dielectrics would enable fabrication of nano-sized devices and circuits. For application area (3), research effort will focus on novel hybrid phototransistors. Use of different light absorbing organic dyes functionalised onto the oxide channel will be explored as a mean for developing high sensitivity phototransistors and full colour sensing arrays. Organic dyes will also be combined with nano-sized transistors to demonstrate integrated nano-scale optoelectronics. The unique combination of bottom-up and top-down strategies adopted in this project will lead to the development of novel high performance devices with a host of existing and new applications."
Summary
"I propose a structured multidisciplinary research programme that seeks to combine advanced materials, such as metal oxides and organics, with novel fabrication methods to develop devices for application in: (1) large area electronics, (2) integrated nanoelectronics and (3) sensors. At the heart of this programme lies the development of novel oxide semiconductors. These will be synthesised from solution using precursors. Chemical doping via physical blending will be explored for the tuning of the electronic properties of these compounds. This simple approach will enable the rapid development of a library of materials far beyond those accessible by traditional methods. Oxides will then be combined with inorganic/organic dielectrics to demonstrate low power transistors. Ultimate target for application area (1) is the development of transistors with hole/electron mobilities exceeding 20/200 cm^2/Vs respectively. For application area (2) I will combine the precursor formulations with advanced scanning thermochemical nanolithography. A heated atomic force microscope tip will be used for the local chemical conversion of the precursor to oxide with sub-50 nm resolution. This will enable patterning of nanostructures with desirable shape and size. Sequential patterning of semi/conductive layers combined with SAM dielectrics would enable fabrication of nano-sized devices and circuits. For application area (3), research effort will focus on novel hybrid phototransistors. Use of different light absorbing organic dyes functionalised onto the oxide channel will be explored as a mean for developing high sensitivity phototransistors and full colour sensing arrays. Organic dyes will also be combined with nano-sized transistors to demonstrate integrated nano-scale optoelectronics. The unique combination of bottom-up and top-down strategies adopted in this project will lead to the development of novel high performance devices with a host of existing and new applications."
Max ERC Funding
1 497 798 €
Duration
Start date: 2012-01-01, End date: 2016-12-31
Project acronym AQUMET
Project Atomic Quantum Metrology
Researcher (PI) Morgan Wilfred Mitchell
Host Institution (HI) FUNDACIO INSTITUT DE CIENCIES FOTONIQUES
Call Details Starting Grant (StG), PE2, ERC-2011-StG_20101014
Summary This project aims to detect magnetic fields with high spatial and temporal resolution and unprecedented sensitivity using ultra-cold atoms as interferometric sensors. The project will, on the one hand, test and demonstrate the most advanced concepts in the dynamic field of quantum metrology, and on the other hand, develop measurement techniques with the potential to transform existing fields and open new ones to study.
Quantum metrology is in an exciting phase: on the one hand, a long-held goal of improving gravita- tional wave detection appears near at hand. At the same time, atomic instruments including atomic clocks, atomic gravimeters and atomic magnetometers are setting records in detection of time, ac- celeration, and fields, with revolutionary potential in several areas. This has stimulated new theory, including remarkable proposals suggesting that long-established “ultimate” limits can in fact be sur- passed.
This project will study quantum metrology applied to atomic sensors by developing a versatile and highly sensitive cold atom magnetometer. We set an ambitious goal: to demonstrate record sensi- tivity, and then to improve on that sensitivity using quantum entanglement. This ground-breaking accomplishment will show the way to super-precise measurements in many fields.
Fundamental topics in quantum metrology will be explored using the advanced magnetometry sys- tem. Nonlinear quantum metrology proposes to surpass the Heisenberg limit using inter-particle interactions. Compressed sensing aims to surpass the Nyquist limit, obtaining more information than normally allowed.
Summary
This project aims to detect magnetic fields with high spatial and temporal resolution and unprecedented sensitivity using ultra-cold atoms as interferometric sensors. The project will, on the one hand, test and demonstrate the most advanced concepts in the dynamic field of quantum metrology, and on the other hand, develop measurement techniques with the potential to transform existing fields and open new ones to study.
Quantum metrology is in an exciting phase: on the one hand, a long-held goal of improving gravita- tional wave detection appears near at hand. At the same time, atomic instruments including atomic clocks, atomic gravimeters and atomic magnetometers are setting records in detection of time, ac- celeration, and fields, with revolutionary potential in several areas. This has stimulated new theory, including remarkable proposals suggesting that long-established “ultimate” limits can in fact be sur- passed.
This project will study quantum metrology applied to atomic sensors by developing a versatile and highly sensitive cold atom magnetometer. We set an ambitious goal: to demonstrate record sensi- tivity, and then to improve on that sensitivity using quantum entanglement. This ground-breaking accomplishment will show the way to super-precise measurements in many fields.
Fundamental topics in quantum metrology will be explored using the advanced magnetometry sys- tem. Nonlinear quantum metrology proposes to surpass the Heisenberg limit using inter-particle interactions. Compressed sensing aims to surpass the Nyquist limit, obtaining more information than normally allowed.
Max ERC Funding
1 387 000 €
Duration
Start date: 2012-01-01, End date: 2016-12-31
Project acronym ASMIDIAS
Project Asymmetric microenvironments by directed assembly: Control of geometry, topography, surface biochemistry and mechanical properties via a microscale modular design principle
Researcher (PI) Holger Dr. Schönherr
Host Institution (HI) UNIVERSITAET SIEGEN
Call Details Starting Grant (StG), PE5, ERC-2011-StG_20101014
Summary The interaction of cells with the extracellular matrix or neighboring cells plays a crucial role in many cellular functions, such as motility, differentiation and controlled cell death. Expanding on pioneering studies on defined 2-D model systems, the role of the currently known determinants (geometry, topography, biochemical functionality and mechanical properties) is currently addressed in more relevant 3-D matrices. However, there is a clear lack in currently available approaches to fabricate well defined microenvironments, which are asymmetric or in which these factors can be varied independently. The central objective of ASMIDIAS is the development of a novel route to asymmetric microenvironments for cell-matrix interaction studies. Inspired by molecular self-assembly on the one hand and guided macroscale assembly on the other hand, directed assembly of highly defined microfabricated building blocks will be exploited to this end. In this modular design approach different building blocks position themselves during assembly on pre-structured surfaces to afford enclosed volumes that are restricted by the walls of the blocks. The project relies on two central elements. For the guided assembly, the balance of attractive and repulsive interactions between the building blocks (and its dependence on the object dimensions) and the structured surface shall be controlled by appropriate surface chemistry and suitable guiding structures. To afford the required functionality, new approaches to (i) topographically structure, (ii) biochemically functionalize and pattern selected sides of the microscale building blocks and (iii) to control their surface elastic properties via surface-attached polymers and hydrogels, will be developed.The resulting unique asymmetric environments will facilitate novel insight into cell-matrix interactions, which possess considerable relevance in the areas of tissue engineering, cell (de)differentiation, bacteria-surface interactions and beyond.
Summary
The interaction of cells with the extracellular matrix or neighboring cells plays a crucial role in many cellular functions, such as motility, differentiation and controlled cell death. Expanding on pioneering studies on defined 2-D model systems, the role of the currently known determinants (geometry, topography, biochemical functionality and mechanical properties) is currently addressed in more relevant 3-D matrices. However, there is a clear lack in currently available approaches to fabricate well defined microenvironments, which are asymmetric or in which these factors can be varied independently. The central objective of ASMIDIAS is the development of a novel route to asymmetric microenvironments for cell-matrix interaction studies. Inspired by molecular self-assembly on the one hand and guided macroscale assembly on the other hand, directed assembly of highly defined microfabricated building blocks will be exploited to this end. In this modular design approach different building blocks position themselves during assembly on pre-structured surfaces to afford enclosed volumes that are restricted by the walls of the blocks. The project relies on two central elements. For the guided assembly, the balance of attractive and repulsive interactions between the building blocks (and its dependence on the object dimensions) and the structured surface shall be controlled by appropriate surface chemistry and suitable guiding structures. To afford the required functionality, new approaches to (i) topographically structure, (ii) biochemically functionalize and pattern selected sides of the microscale building blocks and (iii) to control their surface elastic properties via surface-attached polymers and hydrogels, will be developed.The resulting unique asymmetric environments will facilitate novel insight into cell-matrix interactions, which possess considerable relevance in the areas of tissue engineering, cell (de)differentiation, bacteria-surface interactions and beyond.
Max ERC Funding
1 484 100 €
Duration
Start date: 2011-11-01, End date: 2016-10-31
Project acronym BAYES OR BUST!
Project Bayes or Bust: Sensible Hypothesis Tests for Social Scientists
Researcher (PI) Eric-Jan Wagenmakers
Host Institution (HI) UNIVERSITEIT VAN AMSTERDAM
Call Details Starting Grant (StG), SH4, ERC-2011-StG_20101124
Summary The goal of this proposal is to develop and promote Bayesian hypothesis tests for social scientists. By and large, social scientists have ignored the Bayesian revolution in statistics, and, consequently, most social scientists still assess the veracity of experimental effects using the same methodology that was used by their advisors and the advisors before them. This state of affairs is undesirable: social scientists conduct groundbreaking, innovative research only to analyze their results using methods that are old-fashioned or even inappropriate. This imbalance between the science and the statistics has gradually increased the pressure on the field to change the way inferences are drawn from their data. However, three requirements need to be fulfilled before social scientists are ready to adopt Bayesian tests of hypotheses. First, the Bayesian tests need to be developed for problems that social scientists work with on a regular basis; second, the Bayesian tests need to be default or objective; and, third, the Bayesian tests need to be available in a user-friendly computer program. This proposal seeks to make major progress on all three fronts.
Concretely, the projects in this proposal build on recent developments in the field of statistics and use the default Jeffreys-Zellner-Siow priors to compute Bayesian hypothesis tests for regression, correlation, the t-test, and different versions of analysis of variance (ANOVA). A similar approach will be used to develop Bayesian hypothesis tests for logistic regression and the analysis of contingency tables, as well as for popular latent process methods such as factor analysis and structural equation modeling. We aim to implement the various tests in a new computer program, Bayes-SPSS, with a similar look and feel as the frequentist spreadsheet program SPSS (i.e., Statistical Package for the Social Sciences). Together, these projects may help revolutionize the way social scientists analyze their data.
Summary
The goal of this proposal is to develop and promote Bayesian hypothesis tests for social scientists. By and large, social scientists have ignored the Bayesian revolution in statistics, and, consequently, most social scientists still assess the veracity of experimental effects using the same methodology that was used by their advisors and the advisors before them. This state of affairs is undesirable: social scientists conduct groundbreaking, innovative research only to analyze their results using methods that are old-fashioned or even inappropriate. This imbalance between the science and the statistics has gradually increased the pressure on the field to change the way inferences are drawn from their data. However, three requirements need to be fulfilled before social scientists are ready to adopt Bayesian tests of hypotheses. First, the Bayesian tests need to be developed for problems that social scientists work with on a regular basis; second, the Bayesian tests need to be default or objective; and, third, the Bayesian tests need to be available in a user-friendly computer program. This proposal seeks to make major progress on all three fronts.
Concretely, the projects in this proposal build on recent developments in the field of statistics and use the default Jeffreys-Zellner-Siow priors to compute Bayesian hypothesis tests for regression, correlation, the t-test, and different versions of analysis of variance (ANOVA). A similar approach will be used to develop Bayesian hypothesis tests for logistic regression and the analysis of contingency tables, as well as for popular latent process methods such as factor analysis and structural equation modeling. We aim to implement the various tests in a new computer program, Bayes-SPSS, with a similar look and feel as the frequentist spreadsheet program SPSS (i.e., Statistical Package for the Social Sciences). Together, these projects may help revolutionize the way social scientists analyze their data.
Max ERC Funding
1 498 286 €
Duration
Start date: 2012-05-01, End date: 2017-04-30
Project acronym Beacon
Project Beacons in the Dark
Researcher (PI) Paulo César Carvalho Freire
Host Institution (HI) MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Call Details Starting Grant (StG), PE9, ERC-2011-StG_20101014
Summary BEACON aims at performing an ambitious multi-disciplinary (optical, radio astronomy and theoretical physics) study to enable a fundamentally improved understanding of gravitation and space-time. For almost a century Einstein's general relativity has been the last word on gravity. However, superstring theory predicts new gravitational phenomena beyond relativity. In this proposal I will attempt to detect these new phenomena, with a sensitivity 20 times better than state-of-the-art attempts. A successful detection would take physics beyond its current understanding of the Universe.
These new gravitational phenomena are emission of dipolar gravitational waves and the violation of the strong equivalence principle (SEP). I plan to look for them by timing newly discovered binary pulsars. I will improve upon the best current limits on dipolar gravitational wave emission by a factor of 20 within the time of this proposal. I also plan to develop a test of the Strong Equivalence Principle using a new pulsar/main-sequence star binary. The precision of this test is likely to surpass the current best limits within the time frame of this proposal and then keep improving indefinitely with time. This happens because this is the cleanest gravitational experiment ever carried out.
In order to further these goals, I plan to build the ultimate pulsar observing system. By taking advantage of recent technological advances in microwave engineering (particularly sensitive ultra-wide band receivers) digital electronics (fast analogue-to-digital converters and digital spectrometers) and computing, my team and me will be able to greatly improve the sensitivity and precision for pulsar timing experiments and exploit the capabilities of modern radio telescopes to their limits.
Pulsars are the beacons that will guide me in these new, uncharted seas.
Summary
BEACON aims at performing an ambitious multi-disciplinary (optical, radio astronomy and theoretical physics) study to enable a fundamentally improved understanding of gravitation and space-time. For almost a century Einstein's general relativity has been the last word on gravity. However, superstring theory predicts new gravitational phenomena beyond relativity. In this proposal I will attempt to detect these new phenomena, with a sensitivity 20 times better than state-of-the-art attempts. A successful detection would take physics beyond its current understanding of the Universe.
These new gravitational phenomena are emission of dipolar gravitational waves and the violation of the strong equivalence principle (SEP). I plan to look for them by timing newly discovered binary pulsars. I will improve upon the best current limits on dipolar gravitational wave emission by a factor of 20 within the time of this proposal. I also plan to develop a test of the Strong Equivalence Principle using a new pulsar/main-sequence star binary. The precision of this test is likely to surpass the current best limits within the time frame of this proposal and then keep improving indefinitely with time. This happens because this is the cleanest gravitational experiment ever carried out.
In order to further these goals, I plan to build the ultimate pulsar observing system. By taking advantage of recent technological advances in microwave engineering (particularly sensitive ultra-wide band receivers) digital electronics (fast analogue-to-digital converters and digital spectrometers) and computing, my team and me will be able to greatly improve the sensitivity and precision for pulsar timing experiments and exploit the capabilities of modern radio telescopes to their limits.
Pulsars are the beacons that will guide me in these new, uncharted seas.
Max ERC Funding
1 892 376 €
Duration
Start date: 2011-09-01, End date: 2016-08-31
