ERC FUNDED PROJECTS

What is the origin of cosmic rays, what are the dominant acceleration mechanisms in relativistic shocks, how do cosmic rays self-consistently influence the shock dynamics, how are relativistic collisionless shocks formed are longstanding scientific questions, closely tied to extreme plasma physics processes, and where a close interplay between the micro-instabilities and the global dynamics is critical. Relativistic shocks are closely connected with the propagation of intense streams of particles pervasive in many astrophysical scenarios. The possibility of exciting shocks in the laboratory will also be available very soon with multi-PW lasers or intense relativistic particle beams. Computational modeling is now established as a prominent research tool, by enabling the fully kinetic modeling of these systems for the first time. With the fast paced developments in high performance computing, the time is ripe for a focused research programme on simulation-based studies of relativistic shocks. This proposal therefore focuses on using self-consistent ab initio massively parallel simulations to study the physics of relativistic shocks, bridging the gap between the multidimensional microphysics of shock onset, formation, and propagation and the global system dynamics. Particular focus will be given to the shock acceleration mechanisms and the radiation signatures of the various physical processes, with the goal of solving some of the central questions in plasma/relativistic phenomena in astrophysics and in the laboratory, and opening new avenues between theoretical/massive computational studies, laboratory experiments and astrophysical observations.

1 588 800 €

Start date: 2011-06-01, End date: 2016-07-31

New generations of devices for tissue engineering (TE) should rationalize better the physical and biochemical cues operating in tandem during native regeneration, in particular at the scale/organizational-level of the stem cell niche. The understanding and the deconstruction of these factors (e.g. multiple cell types exchanging both paracrine and direct signals, structural and chemical arrangement of the extra-cellular matrix, mechanical signals…) should be then incorporated into the design of truly biomimetic biomaterials. ATLAS proposes rather unique toolboxes combining smart biomaterials and cells for the ground-breaking advances of engineering fully time-self-regulated complex 2D and 3D devices, able to adjust the cascade of processes leading to faster high-quality new tissue formation with minimum pre-processing of cells. Versatile biomaterials based on marine-origin macromolecules will be used, namely in the supramolecular assembly of instructive multilayers as nanostratified building-blocks for engineer such structures. The backbone of these biopolymers will be equipped with a variety of (bio)chemical elements permitting: post-processing chemistry and micro-patterning, specific/non-specific cell attachment, and cell-controlled degradation. Aiming at being applied in bone TE, ATLAS will integrate cells from different units of tissue physiology, namely bone and hematopoietic basic elements and consider the interactions between the immune and skeletal systems. These ingredients will permit to architect innovative films with high-level dialogue control with cells, but in particular sophisticated quasi-closed 3D capsules able to compartmentalise such components in a “globe-like” organization, providing local and long-range order for in vitro microtissue development and function. Such hybrid devices could be used in more generalised front-edge applications, including as disease models for drug discovery or test new therapies in vitro.

2 498 988 €

Start date: 2015-12-01, End date: 2021-10-31

The purpose of this proposal is to establish new fundamental insight of the reactivity and thereby the catalytic activity of oxides, nitrides, phosphides and sulfides (O-, N-, P-, S- ides) in the Cluster-Nanoparticle transition regime. We will use this insight to develop new catalysts through an interactive loop involving DFT simulations, synthesis, characterization and activity testing. The overarching objective is to make new catalysts that are efficient for production of solar fuels and chemicals to facilitate the implementation of sustainable energy, e.g. electrochemical hydrogen production and reduction of CO2 and N2 through both electrochemical and thermally activated processes. Recent research has identified why there is a lack of significant progress in developing new more active catalysts. Chemical scaling-relations exist among the intermediates, making it difficult to find a reaction pathway, which provides a flat potential energy landscape - a necessity for making the reaction proceed without large losses. My hypothesis is that going away from the conventional size regime, > 2 nm, one may break such chemical scaling-relations. Non-scalable behavior means that adding an atom results in a completely different reactivity. This drastic change could be even further enhanced if the added atom is a different element than the recipient particle, providing new freedom to control the reaction pathway. The methodology will be based on setting up a specifically optimized instrument for synthesizing such mass-selected clusters/nanoparticles. Thus far, researchers have barely explored this size regime. Only a limited amount of studies has been devoted to inorganic entities of oxides and sulfides; nitrides and phosphides are completely unexplored. We will employ atomic level simulations, synthesis, characterization, and subsequently test for specific reactions. This interdisciplinary loop will result in new breakthroughs in the area of catalyst material discovery.

2 500 000 €

Start date: 2017-09-01, End date: 2023-06-30

"With COULOMBUS I will explore the new electronic world I recently found in marine sediment; a living world featuring transmission of coulombs of electrons over long distances through a grid of unknown origin and composition. This is a great challenge to science, and I will specifically - Unravel function, expansion, resilience, and microbial engineering of the conductive grid - Identify microbial and geological processes related to long distance electron transfer today and in the past - Introduce the electron as a new element in biogeochemical and ecological models. - Map the range of sediment and soil habitats featuring biogeoelectric currents Incubations of marine sediment will serve as the “base camp” for the surveys. Here I consistently observe that current sources extending centimetres down deliver electrons for most of the oxygen consumption, and here my array of advanced microsensors and biogeochemical methods works well. My team will record electric currents and biogeochemical changes as we manipulate mechanical, chemical, and biological conditions, thereby getting to an understanding of the interplay between conductors, microorganisms, electron donors, electron acceptors, and minerals. Next we take the methods out in the sea to evaluate biogeoelectricity in situ using robots. Other aquatic environments will also be screened. The ultimate outdoor challenge will come as I lead the team into soils where surface potentials suggest biogeoelectric currents deep down. All observations, experiments, and models will be directed to answer the groundbreaking questions: What physics and microbial engineering can explain long distance electron conductance in nature? How do electric microbial communities evolve and how do they shape element cycling? What signatures of biogeoelectricity are left in the geological record of earth history? If I succeed I will have opened up many new exciting research routes for the followers."

2 155 300 €

Start date: 2012-03-01, End date: 2017-02-28