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How does one infer the dynamics of a DNA minicircle in solution? How does one align the neuronal firing patterns of several neurons across individuals? These questions are intrinsically statistical, but nevertheless escape the traditional tools of statistics. The ComplexData project investigated such questions from a mathematical and an applied context.
Slavery represents a dark and unclosed page in the history of mankind. Even if legally abolished by all countries of the world, its legacies shape the present in a plurality of ways and often overlap with the phenomena that scholars, activists and policy-makers target as new slaveries. Which are the consequences of slavery after its legal death? Should new forms of labor exploitation and human bondage also be read in this key? Or are they the result of recent economic, political and social transformations?
An ERC-funded project is conducting groundbreaking research into a rare form of leukaemia, proving the effectiveness in patients of non-chemotherapy-based treatments that target the genetic cause of the disease. The Hairy Cell Leukemia project, launched by the Institute of Hematology at the University of Perugia in Italy with funding from the European Research Council, is one of the world’s foremost initiatives to develop a targeted therapy for hairy cell leukaemia (HCL), a rare form of blood cancer.
Assisted Reproductive Technology (ART) is increasingly used to help women become pregnant. The most common technique is in vitro fertilisation, i.e. the transfer of fertilised human eggs into a woman's uterus. However, ART can imply risks for the embryo during the pregnancy or even later in life. With a grant of the European Research Council (ERC), Polish researcher Dr Grazyna Ewa Ptak has analysed sheeps embryos. With her team at the University of Teramo, she has discovered the precise timing and nature of placental disorders consequent to ART. Her findings can greatly improve reproductive technologies and lead to safer pregnancies for both women and animals.
Mathematics might seem like an abstract discipline, remote from real-world applications but their equations can significantly help understand and simulate the functioning of nature. Professor Alfio Quarteroni of the École Polytechnique Fédérale de Lausanne (EPFL, Switzerland) is leading the Mathcard project in developing mathematical models of the blood flow in our cardiovascular system. On the occasion of World Heart Day, he explains how his project could help surgeons and save lives.