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What if damaged brain cells could be replaced? ERC grantee Malin Parmar has developed innovative genetic reprogramming techniques that can produce new brain cells from other types of cells in the body, opening up new therapeutic pathways to combat disorders such as Parkinson’s and Alzheimer’s.
Effective treatment for obesity remains a challenge and the only intervention proven to maintain weight loss is bariatric surgery. Intrigued by the beneficial effect that this procedure has on the composition of gut microbiota, Dr Fredrik Bäckhed explores the possibility of mimicking these changes to develop a treatment for obesity that won’t require going under the knife.
ELECTION SERIES #7
Why are some people more likely to vote or stand for election than others? Researchers based in Sweden are doing some deep data diving to find out how our social surroundings and our genes influence political participation.
ELECTION SERIES #2
Because the European Parliament represents such a diverse group of people, with different cultural and political backgrounds, it is the perfect ground to understand how gender equality operates in the halls of power. ERC grantee Johanna Kantola and her team have shadowed many members of Parliament and their teams, to study gender practices and policies inside Europe’s legislative machine.
At the forefront of medicine, gene therapy is based on the insertion of genes into an individual's cells and tissues to treat a disease. Scientists are currently testing several approaches to this experimental technique. One of them, Prof. Seppo Ylä-Herttuala, intends to develop a novel method to treat myocardial ischemia by activating endogenous genes to propel angiogenesis. If successful, he will open a new era in gene therapy.
How does the past inform the lives of children and young people? A global team of EU-funded researchers is examining this issue by assessing how stories from classical antiquity impact on popular culture and society. The project’s results and outputs will provide valuable resources for scholars and teachers.
Ole Kamstrup, MD., MSc., is a pensioner and lives north of Copenhagen in Denmark. He has been diagnosed with Parkinson's disease ten years ago. Since 2013, Mr Kamstrup has been in contact with Professor Deniz Kirik, a neuroscientist at Lund University in Sweden. Professor Kirik, who was awarded an ERC Starting Grant in 2009, develops new therapies for Parkinson’s disease, using viral vectors to deliver therapeutic genes to the brain. An ERC Proof of Concept grant enabled him to start carrying out a market evaluation and writing a business plan for the promising therapy.
Originally published in March 2017 as part of the multimedia campaign "ERC - 10 years – 10 portraits."
Cardiovascular diseases (CVD) are a major cause of morbidity and mortality in Europe. Prevention relies on measuring traditional risk factors such as age, gender, hypertension, diabetes, hypercholesterolemia and smoking. However, many individuals, apparently at low-risk, still develop CVD. Improving predictions beyond the traditional risk factors is the challenge undertaken by Prof. Olle Melander.
During the 3rd and 2nd millennium BC, the European continent experienced important social and cultural transformations, with the introduction of metal and the emergence of new languages and identities. Recent theories suggest that these major changes were triggered by people’s migrations and cultural transmissions, challenging the perception of European prehistory as a series of unrelated local developments.