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Haematopoietic Stem Cells (HSCs) are blood cells located in the bone marrow. These cells are extensively used in research to develop treatments for many severe diseases, including HIV and multiple sclerosis, and their transplant is a key therapy for certain types of cancer like leukemia and multiple myeloma. However, the use of HSCs is seriously constrained by their limited availability since growing them in the lab does not produce very large quantities. There is therefore an urgent need for methods allowing scientists to multiply HSCs, without losing any of their properties.
Plants form a key interface between the Earth’s surface and the atmosphere by exchanging carbon, water and energy with their environment. They also release chemicals called “volatile organic compounds” (VOCs) in the atmosphere. However, the overall impact of these gas compounds is poorly understood. Ülo Niinemets and his team look at the role of plants in large-scale Earth processes and how they affect air quality and the Earth surface temperature, solar radiation and precipitation.
Is a precise answer always better than a slightly less detailed one? Not necessarily. Some problems could take forever to compute and tie up vast IT capacity. Where solutions are needed urgently, e.g. in business or manufacturing, near-enough can be more than enough. ERC-funded research has produced a library of fast, powerful approximation algorithms.