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27-07-2017 | 3D illustration ©www.shutterstock.com

Understanding membrane trafficking in space and time

ERC grantee Prof. Maria Antonietta De Matteis studies membrane trafficking in cells and how its components interact and are regulated to guarantee a healthy cell function. Her work could revolutionise our understanding of this key biological process.

30-11-2016 | Image: FISH analysis performed by Sara Carloni, PhD: in situ staining of bacteria (in green) in the gut lumen. Nuclei stained in blue (dapi).

Gut bacteria could hold key to new treatments

An ERC-funded project has significantly increased understanding of the crucial role that microorganisms in the gut play in maintaining health. The findings have since led to a patent, as well as a follow-on project that could one day steer the way to new targeted treatments for diseases, including cancer.

25-02-2016 | © picture

Effective targeted treatment for hairy cell leukaemia

An ERC-funded project is conducting groundbreaking research into a rare form of leukaemia, proving the effectiveness in patients of non-chemotherapy-based treatments that target the genetic cause of the disease. The Hairy Cell Leukemia project, launched by the Institute of Hematology at the University of Perugia in Italy with funding from the European Research Council, is one of the world’s foremost initiatives to develop a targeted therapy for hairy cell leukaemia (HCL), a rare form of blood cancer.

15-04-2015 | Image:© Guidotti et al./Cell 2015

Lymphocytes versus hepatitis B virus: caught in action

For the first time ever, two ERC grantees, Prof. Luca G. Guidotti and Dr Matteo Iannacone, have observed in vivo how specific white blood cells, so-called cytotoxic T lymphocytes, identify, target and attack liver cells that are infected with the hepatitis B virus. To witness these immune cells in action in real time, the two scientists developed advanced, dynamic imaging techniques. An estimated 240 million people are chronically infected with hepatitis B worldwide. This discovery, published today in the scientific journal Cell, opens new horizons for the development of novel therapies.

28-10-2013 | © picture

Towards better reproductive technologies and safer pregnancies

Assisted Reproductive Technology (ART) is increasingly used to help women become pregnant. The most common technique is in vitro fertilisation, i.e. the transfer of fertilised human eggs into a woman's uterus. However, ART can imply risks for the embryo during the pregnancy or even later in life. With a grant of the European Research Council (ERC), Polish researcher Dr Grazyna Ewa Ptak has analysed sheeps embryos. With her team at the University of Teramo, she has discovered the precise timing and nature of placental disorders consequent to ART. Her findings can greatly improve reproductive technologies and lead to safer pregnancies for both women and animals.

28-10-2010 | © picture

From Europe to China: 13,000km pioneering expedition with driverless vans led by an ERC grantee reached end goal

Prof. Alberto Broggi's "Intercontinental Autonomous Challenge" has arrived at its final destination after a 13,000 km trip across two continents.