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While women inherit two X chromosomes, the expressions of one of them is shut down during embryonic development. Men have one X chromosome and one Y chromosome. The switching off of women’s second X chromosome is thought to compensate for the presence of only one X in males versus two in females, to balance for X-linked gene products between the sexes. X-chromosome inactivation is also one of the clearest examples of what epigenetic mechanisms do to our genetic material: the DNA of the genes on the X is still present but not actively expressed or needed. Prof. Edith Heard was awarded ERC grants to understand the intricate processes behind the phenomenon, with unexpected results that changed the way gene regulation is now looked at.
As Europe continues to confront the consequences of the 2008 financial crisis it becomes ever-more important to fathom not only how Europe can return to productive levels of employment, but why it is failing to do so. Professor Pissarides’s ERC research examines both what kind of jobs Europeans do and future trends in employment. He will present his research to the public at TEDx Brussels event on 1 December.
Lights, camera... action! On the eve of the Oscars, we take a look at an ERC project in the field of film. ERC grantee Marcelo Bertalmío loves cinema so much that he made it the core of his research. A filmmaker himself – he has directed two movies – Dr. Bertalmío is developing a series of image processing algorithms that will create a better and cheaper way to shoot movies, whilst granting more artistic freedom to directors and cinematographers. He is the author of a book, Image Processing for Cinema (2014), which has already received plaudits from the film industry.