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Our immune system recognizes and fights infections in a constantly changing environment, where new pathogenic threats emerge. At the crossroad between physics and biology, Prof. Aleksandra Walczak investigates the fascinating process that allows the immune system to be always ready to adapt and evolve to face new dangers.
Headscarves, mosques and halal shops — many EU citizens are Muslims, but visible signs of their faith are often viewed with distrust. What some Europeans see as a right to express their identity, others regard as a threat to societal core values. Insights from ERC-funded research into emblematic controversies may help to find a way forward.
Prof. Nicolosi received a BSc with honors in Chemistry from the University of Catania, Italy, and Ph.D. in Physics from Trinity College Dublin. Today she is Professor of Nanomaterials & Advanced Microscopy at the School of Chemistry, Trinity College Dublin, and principal investigator at the Centers for Research on Adaptive Nanostructures and Nanodevices (CRANN) and for Advanced Materials and BioEngineering (AMBER). Her interdisciplinary research focuses on low-dimensional nanomaterials, including graphene. She received three top-up ERC Proof of Concept grants to commercialize her findings.
Originally published in March 2017 as part of the multimedia campaign "ERC - 10 years – 10 portraits."
While women inherit two X chromosomes, the expressions of one of them is shut down during embryonic development. Men have one X chromosome and one Y chromosome. The switching off of women’s second X chromosome is thought to compensate for the presence of only one X in males versus two in females, to balance for X-linked gene products between the sexes. X-chromosome inactivation is also one of the clearest examples of what epigenetic mechanisms do to our genetic material: the DNA of the genes on the X is still present but not actively expressed or needed. Prof. Edith Heard was awarded ERC grants to understand the intricate processes behind the phenomenon, with unexpected results that changed the way gene regulation is now looked at.