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Why do so many diabetes patients develop kidney disease, and how can we improve prevention? EU-funded research has examined insulin-related processes at play in impaired renal function — and it may have found a way to protect key cells that help to filter our blood.
An international team of researchers, led by ERC grantee Prof Rune Linding, discovered how genetic cancer mutations attack the networks controlling human cells. This knowledge is critical for the future development of personalized precision cancer treatments.
Prevention and early detection largely determine the outcome of most cancers. Prof. Päivi Peltomäki studies how tumours arise and progress, with a view to identifying biomarkers of our susceptibility to developing cancer. With the ERC grant, the team has created a single-step, early diagnosis kit for colorectal cancer.
In 2012, 2.8 million people in the EU were diagnosed with cancer. It is the second most common cause of death in the Union – three out of 10 deaths for men, and two out of 10 deaths for women – a figure that is expected to rise due to the ageing European population. Dr Danijela Matic Vignjevic’s STARLIN project is using ERC funding to understand how normal cells become cancerous and spread.
With their transparent skin and a known genome, the zebrafish larvae are emerging as a model for neuroscientists. It enables researchers to monitor large portions of the brain in an intact behaving vertebrate. Dr German Sumbre, an ERC grantee from Argentina, uses zebrafish in order to achieve a better understanding of the neural mechanisms of sensory perception, and as a means of providing new insights into neurological disorders.
The DOFOCO project aims to better understand how forests can help lessen the effects of global warming, by bringing together advanced models and data from the life and earth sciences. Such research takes an additional dimension this year, in the context of the United Nations International Year of Forests 2011.