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Antibiotics are amongst the most crucial discoveries in modern medicine. However, the surge in microbial resistance to these, now common, drugs is a challenge that medical researchers work hard to tackle. Prof. Susanne Häußler from the Helmholtz Centre for Infection Research believes early diagnostic tools could shift the paradigm of how we battle this problem.
Parents may threat at the idea of their children playing in fields and sheds, but research shows that those who grew up in farms, where this is common occurrence, are less likely to suffer from allergies and asthma. Prof. Erika von Mutius leads a team of researchers, that uses this knowledge to investigate how we could treat such conditions more effectively.
The Earth is made of layers, just like a big onion, composed of different materials. However, the compounds forming these layers are not static, flowing from one stratum to another, following patterns still not entirely understood. Prof. Patrick Cordier tries to model the real conditions minerals are subjected to beneath the Earth’s crust. His aim is to understand the forces driving tectonic plates so we can better comprehend phenomena like earthquakes and volcanic eruptions.
Thousands of new cases of head-and-neck cancer - which includes cancer of the larynx, throat, mouth, nose and salivary glands - are diagnosed every year in Europe. Despite improvements in diagnostic and therapeutic tools, these malignant tumours still show high resistance to current treatments. Dr Daniela Thorwarth is working on tailored therapies for individual patients.
Through her work with the fruit fly Drosophila santomea, Dr Virginie Orgogozo aims to answer one of the most challenging questions of modern evolutionary biology: how do observable characteristics change between species and yet remain stable in a given species?
Researchers supported by the ERC have sampled magmatic gases derived from the Earth's mantle in the Eifel region in Germany. Their analysis of xenon, a rare and inert gas, sampled in bubbling mineral water could bring new insights into the origin of volatile elements, water and gases, that allowed life to develop on Earth.
While women inherit two X chromosomes, the expressions of one of them is shut down during embryonic development. Men have one X chromosome and one Y chromosome. The switching off of women’s second X chromosome is thought to compensate for the presence of only one X in males versus two in females, to balance for X-linked gene products between the sexes. X-chromosome inactivation is also one of the clearest examples of what epigenetic mechanisms do to our genetic material: the DNA of the genes on the X is still present but not actively expressed or needed. Prof. Edith Heard was awarded ERC grants to understand the intricate processes behind the phenomenon, with unexpected results that changed the way gene regulation is now looked at.
Prof. Ian Thomas Baldwin received an ERC Advanced Grant to study the internal circadian clock of plants. In particular, he wants to understand the ecological consequences of plants fallings ‘out of synch’. In this interview, Prof. Baldwin shares some of his research findings and explains why he has chosen to make his study results openly available.
Artur Avila is a franco-brazilian leading mathematician and an ERC grantee since 2010. At the age of 16, he won the International Mathematical Olympic gold medal and before finishing high school, he received a scholarship for the Instituto Nacional de Matemática Pura e Aplicada (IMPA) of Rio de Janeiro. He is now senior researcher both at the National Center for Scientific Research - CNRS and IMPA. In this interview, Prof. Avila tells us about his international career and the research he conducts both in Brazil and France.
With her degree in biology, Dr Maria-Elena Torres-Padilla left Mexico and embarked on an international career in epigenetics. She completed her PhD at the Pasteur Institute in Paris and then moved to Cambridge University. In 2006 she joined IGBMC in Strasbourg working as a group leader. She has just been appointed Director of the Institute of Epigenetics and Stem Cells of the Helmholtz Zentrum in Munich. Supported by an ERC grant, she studies the mechanisms controlling embryonic cellular plasticity with the aim of shedding new light on today's fertility issues. In this interview she shares her story as a non-European scientist in Europe.