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The deep seafloor covers around 70% of our planet’s surface and is home to a diverse community of microorganisms, mostly bacteria. These single-cell life forms inhabit some of the most extreme places in the world, with freezing waters, permanent darkness, high pressure and little food. ERC grantee Antje Boetius studies these microbes in the abyss and their important role for the Earth’s nutrient cycles.
CRISPR is a widely used molecular biology tool exploiting an immune process discovered in bacteria. Dr David Bikard studies CRISPR in bacterial cells, in conjunction with different DNA repair systems, to create even newer tools. He hopes to gain insight into bacterial genetics, and develop increasingly effective medical treatments.
For the first time ever, a team of scientists and clinicians led by the EU-funded researcher Mickael Tanter has managed to record the brain activity of a premature new-born baby during resting and during an epileptic seizure. Using a non-invasive ultrasound technology, this world premiere is a real game changer for researchers and the medical profession, offering a massive range of applications in neuroimaging and beyond. It is published today in Science Translational Medicine.
Pour la toute première fois, une équipe de scientifiques et des cliniciens dirigée par le chercheur Mickael Tanter, financé par l'UE, a réussi à enregistrer l'activité cérébrale d'un nouveau-né prématuré en phase de repos et lors d'une crise d'épilepsie. À l'aide d'une technologie d'échographie non invasive, cette première mondiale marque un véritable tournant dans le domaine de la recherche et la pratique médicale. Elle offre par ailleurs une vaste gamme d'applications en neuroimagerie et au-delà. L'étude est publiée aujourd'hui dans Science Translational Medicine.
Antibiotics are amongst the most crucial discoveries in modern medicine. However, the surge in microbial resistance to these, now common, drugs is a challenge that medical researchers work hard to tackle. Prof. Susanne Häußler from the Helmholtz Centre for Infection Research believes early diagnostic tools could shift the paradigm of how we battle this problem.
Parents may threat at the idea of their children playing in fields and sheds, but research shows that those who grew up in farms, where this is common occurrence, are less likely to suffer from allergies and asthma. Prof. Erika von Mutius leads a team of researchers, that uses this knowledge to investigate how we could treat such conditions more effectively.
Thousands of new cases of head-and-neck cancer - which includes cancer of the larynx, throat, mouth, nose and salivary glands - are diagnosed every year in Europe. Despite improvements in diagnostic and therapeutic tools, these malignant tumours still show high resistance to current treatments. Dr Daniela Thorwarth is working on tailored therapies for individual patients.
Through her work with the fruit fly Drosophila santomea, Dr Virginie Orgogozo aims to answer one of the most challenging questions of modern evolutionary biology: how do observable characteristics change between species and yet remain stable in a given species?
While women inherit two X chromosomes, the expressions of one of them is shut down during embryonic development. Men have one X chromosome and one Y chromosome. The switching off of women’s second X chromosome is thought to compensate for the presence of only one X in males versus two in females, to balance for X-linked gene products between the sexes. X-chromosome inactivation is also one of the clearest examples of what epigenetic mechanisms do to our genetic material: the DNA of the genes on the X is still present but not actively expressed or needed. Prof. Edith Heard was awarded ERC grants to understand the intricate processes behind the phenomenon, with unexpected results that changed the way gene regulation is now looked at.
Prof. Ian Thomas Baldwin received an ERC Advanced Grant to study the internal circadian clock of plants. In particular, he wants to understand the ecological consequences of plants fallings ‘out of synch’. In this interview, Prof. Baldwin shares some of his research findings and explains why he has chosen to make his study results openly available.