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A European bioengineer has pushed the boundaries of cell manipulation by pioneering a new, droplet-based method of study. His innovation, allowing for the highly detailed observation of cells, has resulted in the launch of a spin-off company as well as further research into cell cultures. Fuelled by a European Research Council (ERC) grant, the technology promises to open doors to new applications in pharmaceuticals, diagnostics and medical research.
Two volunteers are the first above-knee amputees in the world to feel their prosthetic foot and knee in real time. Their bionic prosthesis, developed by a European team of researchers, has sensors that connect to residual nerves in the thigh. The resulting neurofeedback reduces physical and mental strain for prosthesis users as well as their phantom limb pain. They can also walk faster and with more confidence. Researchers, partly supported by ERC funds, recently reported on their achievement in Nature Medicine.
ERC grantee Juergen Brugger and his team have developed biodegradable microresonators that can be heated locally with a wireless system. Doctors could soon be using them in implants to control the release of painkillers within tissue.By Laure-Anne Pessina - Originally published on the EPFL website
How can we develop new materials that meet the extreme challenges of aerospace applications? Seizing the great potential of magnesium as a lightweight metal or making steels more resistant to failure and corrosion are two engineering challenges whose roots lie deep down at the atomic scale. Using models that bridge across scales from the atomic to the observable level, an ERC funded scientist investigates why materials behave and fail the way they do.
CRISPR is a widely used molecular biology tool exploiting an immune process discovered in bacteria. Dr David Bikard studies CRISPR in bacterial cells, in conjunction with different DNA repair systems, to create even newer tools. He hopes to gain insight into bacterial genetics, and develop increasingly effective medical treatments.
Emulsions play a key role both in natural and industrial processes, as they allow the combination of two liquids that do not normally mix and make the blend stable. Yet, when materials solidify or freeze, the complex interactions that take place and affect the final microstructure of the solidified components, are still poorly understood. ERC grantee Sylvain Deville and his team at CNRS have showed that it is possible to use an optical imaging technique to study the freezing of emulsions while the process takes place, a novel method presented in the prestigious journal Science.
Through her work with the fruit fly Drosophila santomea, Dr Virginie Orgogozo aims to answer one of the most challenging questions of modern evolutionary biology: how do observable characteristics change between species and yet remain stable in a given species?
The DOFOCO project aims to better understand how forests can help lessen the effects of global warming, by bringing together advanced models and data from the life and earth sciences. Such research takes an additional dimension this year, in the context of the United Nations International Year of Forests 2011.
Preventing excess waste is a challenge and the need to recycle and produce sustainable materials is increasing. ERC-funded project PARADIGM could influence the design of future plastic-like materials that would break down in the environment the way natural materials do. This innovative technology will also be used for body repair by creating materials that mimic our native tissues and organs.