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Ole Kamstrup, MD., MSc., is a pensioner and lives north of Copenhagen in Denmark. He has been diagnosed with Parkinson's disease ten years ago. Since 2013, Mr Kamstrup has been in contact with Professor Deniz Kirik, a neuroscientist at Lund University in Sweden. Professor Kirik, who was awarded an ERC Starting Grant in 2009, develops new therapies for Parkinson’s disease, using viral vectors to deliver therapeutic genes to the brain. An ERC Proof of Concept grant enabled him to start carrying out a market evaluation and writing a business plan for the promising therapy.
Originally published in March 2017 as part of the multimedia campaign "ERC - 10 years – 10 portraits."
Dr Damian Evans from the École française d’Extrême-Orient and his team used a laser radar mounted on a helicopter to scan the jungle in Cambodia in 2015. What resulted was one of the most important archeological discoveries in recent years.
The EU-funded HYMAGINE project has combined conventional electronic transistors with new magnetism-based ‘spintronic’ devices to improve information processing speeds and reduce energy consumption.
Cardiovascular diseases (CVD) are a major cause of morbidity and mortality in Europe. Prevention relies on measuring traditional risk factors such as age, gender, hypertension, diabetes, hypercholesterolemia and smoking. However, many individuals, apparently at low-risk, still develop CVD. Improving predictions beyond the traditional risk factors is the challenge undertaken by Prof. Olle Melander.
The Earth is made of layers, just like a big onion, composed of different materials. However, the compounds forming these layers are not static, flowing from one stratum to another, following patterns still not entirely understood. Prof. Patrick Cordier tries to model the real conditions minerals are subjected to beneath the Earth’s crust. His aim is to understand the forces driving tectonic plates so we can better comprehend phenomena like earthquakes and volcanic eruptions.
Through her work with the fruit fly Drosophila santomea, Dr Virginie Orgogozo aims to answer one of the most challenging questions of modern evolutionary biology: how do observable characteristics change between species and yet remain stable in a given species?
Researchers supported by the ERC have sampled magmatic gases derived from the Earth's mantle in the Eifel region in Germany. Their analysis of xenon, a rare and inert gas, sampled in bubbling mineral water could bring new insights into the origin of volatile elements, water and gases, that allowed life to develop on Earth.
While women inherit two X chromosomes, the expressions of one of them is shut down during embryonic development. Men have one X chromosome and one Y chromosome. The switching off of women’s second X chromosome is thought to compensate for the presence of only one X in males versus two in females, to balance for X-linked gene products between the sexes. X-chromosome inactivation is also one of the clearest examples of what epigenetic mechanisms do to our genetic material: the DNA of the genes on the X is still present but not actively expressed or needed. Prof. Edith Heard was awarded ERC grants to understand the intricate processes behind the phenomenon, with unexpected results that changed the way gene regulation is now looked at.
During the 3rd and 2nd millennium BC, the European continent experienced important social and cultural transformations, with the introduction of metal and the emergence of new languages and identities. Recent theories suggest that these major changes were triggered by people’s migrations and cultural transmissions, challenging the perception of European prehistory as a series of unrelated local developments.
Artur Avila is a franco-brazilian leading mathematician and an ERC grantee since 2010. At the age of 16, he won the International Mathematical Olympic gold medal and before finishing high school, he received a scholarship for the Instituto Nacional de Matemática Pura e Aplicada (IMPA) of Rio de Janeiro. He is now senior researcher both at the National Center for Scientific Research - CNRS and IMPA. In this interview, Prof. Avila tells us about his international career and the research he conducts both in Brazil and France.