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How can we develop new materials that meet the extreme challenges of aerospace applications? Seizing the great potential of magnesium as a lightweight metal or making steels more resistant to failure and corrosion are two engineering challenges whose roots lie deep down at the atomic scale. Using models that bridge across scales from the atomic to the observable level, an ERC funded scientist investigates why materials behave and fail the way they do.
Microwaves are widely employed in the technologies we use in our daily life - from global navigation systems (like GPS or Galileo), to the satellites used for the weather forecast. They are also important for more ambitious endeavors such as space navigation. The work of Prof. Yanne Chembo has contributed to the next generation of microwaves.
Our soils are inhabited by millions of microorganisms; however, the majority of them lay dormant. In her ERC project, Prof. Dagmar Woebken explores the mechanisms that allow soil microorganisms to go into dormancy and thus survive unfavorable conditions. It is further the goal to reveal the environmental signals that lead to their resuscitation to perform important ecosystems functions.
Honey bees are an important species for ecology and economy, but their population has shrank worryingly. Prof. Philipp Engel focuses on gut microbiota, a critical factor for bee health, to understand how it evolved and diversified over time. His study addresses timely questions about evolution, ecology, microbiology and could eventually contribute to new strategies for managing bee colonies’ health.
This 8 March, the ERC celebrates the achievements of grantee Dr Mariana Graña, a determined researcher in a branch of physics where women are still noticeably underrepresented. She reflects on how far women have come in Theoretical Physics and what is still needed to overcome the gender-role stereotypes associated with this appealing but abstract field of science.
How does one infer the dynamics of a DNA minicircle in solution? How does one align the neuronal firing patterns of several neurons across individuals? These questions are intrinsically statistical, but nevertheless escape the traditional tools of statistics. The ComplexData project investigated such questions from a mathematical and an applied context.
Being able to generate human tissue in vitro in a dish is expected to revolutionise biomedical research. European researchers generated brain organoids to study the mechanisms of various neurological disorders and discover novel drugs to treat them.
CRISPR is a widely used molecular biology tool exploiting an immune process discovered in bacteria. Dr David Bikard studies CRISPR in bacterial cells, in conjunction with different DNA repair systems, to create even newer tools. He hopes to gain insight into bacterial genetics, and develop increasingly effective medical treatments.
Originally published in May 2015
Updated in July 2018
With an aging population, Europe sees a rapid increase in the number of people affected by visual disorders requiring surgical intervention. Building on the recent advances in robotic assistance in surgery as well as in precisely targeted drug delivery therapies, Prof. Bradley Nelson has designed innovative microrobotics tools to overcome the particular difficulty of manual-performed eye surgery.
Prof. Giulio Superti-Furga and his team work on understanding the movement of molecules across human cells. In a paper recently published on Cell Host & Microbe, they outline the significance of a single protein, SLC4A7, in phagocytosis, the body's first line of defence against infection. These results, however, go beyond the context of infectious diseases, with repercussions on our knowledge of processes like inflammation and cancer.