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Effective treatment for obesity remains a challenge and the only intervention proven to maintain weight loss is bariatric surgery. Intrigued by the beneficial effect that this procedure has on the composition of gut microbiota, Dr Fredrik Bäckhed explores the possibility of mimicking these changes to develop a treatment for obesity that won’t require going under the knife.
Applied theatre tells a story not for the purposes of entertainment but for social, economic, political or therapeutic reasons. Prof. Matthias Warstat, funded by the ERC, wants to know more about the growth and impact of this form of theatre across the world.
Severe traffic jams not only have an impact on mobility, they also raise environmental and health issues linked to fuel consumption and air and noise pollution. Prof. Ludovic Leclercq is developing new traffic control models that could tackle road congestion while integrating a green dimension.
Could migration lead to more respect for ethnic and cultural diversity not only in receiving communities but also in sending countries? By observing the effects of Polish migration to the UK and Germany, as a result of the country’s entry in the EU in 2004, Prof. Magdalena Nowicka explores possible answers to this question.
Headscarves, mosques and halal shops — many EU citizens are Muslims, but visible signs of their faith are often viewed with distrust. What some Europeans see as a right to express their identity, others regard as a threat to societal core values. Insights from ERC-funded research into emblematic controversies may help to find a way forward.
Ethiopia has the most ancient tradition of written culture in sub-Saharan Africa. Until today old monasteries and churches, scattered all over the country, hold thousands of precious manuscripts. Yet, for most part, these cultural treasures are stored in precarious conditions. Prof. Denis Nosnitsin intends to preserve and study this rich heritage that soon could be lost forever.
In 2012, 2.8 million people in the EU were diagnosed with cancer. It is the second most common cause of death in the Union – three out of 10 deaths for men, and two out of 10 deaths for women – a figure that is expected to rise due to the ageing European population. Dr Danijela Matic Vignjevic’s STARLIN project is using ERC funding to understand how normal cells become cancerous and spread.
The ability to fine-tune the functioning of blood vessels and the circulatory system is essential for combating the remodelling of the arteries that leads to heart attacks and strokes. It is also needed for the controlled repair of blood vessels after injury – which may otherwise result in a number of serious conditions. ERC grantee Professor Stefanie Dimmeler and her team at Frankfurt University are studying the role ribonucleic acid (RNA) plays in fine-tuning vascular functions – with the aim of developing new therapies for cardiovascular diseases, which are the most prevalent in Europe, due to growing obesity and longer lifespans.
The ‘Gothic’ architectural style, which flourished during the high- and late-medieval periods, from the 12th to 16th centuries AD, gave Europe some of its greatest cathedrals, minsters and churches as well as an architectural treasure house of palaces, town halls and guild buildings among others. Importantly, the soaring open spaces conceived and constructed by the architects of the period were only made possible by the innovative ways of designing and constructing ambitious vaulted ceilings. How did those medieval builders go about designing these huge complex monuments? And in an era without computers and design software, how did they set down their visions and transmit them in usable form to the master builders and masons who created them?
The genetic heredity a person is born with isn't as impossible to change as one might think. In a study published in Cell Metabolism on 7 March 2012 Juleen Zierath, an ERC Advanced grantee 2008, and her team of researchers from the Karolinska Institutet in Sweden showed that when healthy but inactive men and women are made to exercise it actually alters chemical marks on their DNA - in a matter of minutes.