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An ERC-funded project has significantly increased understanding of the crucial role that microorganisms in the gut play in maintaining health. The findings have since led to a patent, as well as a follow-on project that could one day steer the way to new targeted treatments for diseases, including cancer.
Despite recent advances in the fight against cancer, scientific research continues on several fronts. Current studies in the field of nanomedicine are proving very promising. Professor Valentina Cauda, from the Politecnico di Torino, has received funding from the European Research Council (ERC) for a pioneering project in this field, designed to develop therapies to target cancer cells without affecting the surrounding tissue.
Malgrado i recenti progressi nella lotta contro il cancro, la ricerca scientifica non si arresta e continua su vari fronti. Gli studi attualmente condotti nell’ambito della nanomedicina si stanno rivelando molto promettenti. La Prof.ssa Valentina Cauda, del Politecnico di Torino, ha ottenuto un finanziamento dallo European Research Council (ERC) per un progetto d’avanguardia in questo campo, mirato a sviluppare terapie che distruggono le cellule tumorali senza intaccare i tessuti circostanti.
In cosa consiste il suo progetto?
European researchers have designed brain-like artificial neural networks capable of numerical and spatial cognition and written language processing without any explicit training or pre-programming. Their work, based on the machine-learning approach of generative models, significantly advances the development of self-learning artificial intelligence, while also deepening understanding of human cognition.
The Earth is made of layers, just like a big onion, composed of different materials. However, the compounds forming these layers are not static, flowing from one stratum to another, following patterns still not entirely understood. Prof. Patrick Cordier tries to model the real conditions minerals are subjected to beneath the Earth’s crust. His aim is to understand the forces driving tectonic plates so we can better comprehend phenomena like earthquakes and volcanic eruptions.
Through her work with the fruit fly Drosophila santomea, Dr Virginie Orgogozo aims to answer one of the most challenging questions of modern evolutionary biology: how do observable characteristics change between species and yet remain stable in a given species?
Slavery represents a dark and unclosed page in the history of mankind. Even if legally abolished by all countries of the world, its legacies shape the present in a plurality of ways and often overlap with the phenomena that scholars, activists and policy-makers target as new slaveries. Which are the consequences of slavery after its legal death? Should new forms of labor exploitation and human bondage also be read in this key? Or are they the result of recent economic, political and social transformations?
Researchers supported by the ERC have sampled magmatic gases derived from the Earth's mantle in the Eifel region in Germany. Their analysis of xenon, a rare and inert gas, sampled in bubbling mineral water could bring new insights into the origin of volatile elements, water and gases, that allowed life to develop on Earth.
While women inherit two X chromosomes, the expressions of one of them is shut down during embryonic development. Men have one X chromosome and one Y chromosome. The switching off of women’s second X chromosome is thought to compensate for the presence of only one X in males versus two in females, to balance for X-linked gene products between the sexes. X-chromosome inactivation is also one of the clearest examples of what epigenetic mechanisms do to our genetic material: the DNA of the genes on the X is still present but not actively expressed or needed. Prof. Edith Heard was awarded ERC grants to understand the intricate processes behind the phenomenon, with unexpected results that changed the way gene regulation is now looked at.
An ERC-funded project is conducting groundbreaking research into a rare form of leukaemia, proving the effectiveness in patients of non-chemotherapy-based treatments that target the genetic cause of the disease. The Hairy Cell Leukemia project, launched by the Institute of Hematology at the University of Perugia in Italy with funding from the European Research Council, is one of the world’s foremost initiatives to develop a targeted therapy for hairy cell leukaemia (HCL), a rare form of blood cancer.