- Projects & figures
- News & Events
- Managing your project
- About ERC
Finding ways to enlist the bacteria living in our bodies to defend against infections while better understanding their role in promoting antibiotic resistance are key to fighting this growing problem, says Dr Nassos Typas, a microbiologist at the European Molecular Biology Laboratory in Heidelberg, Germany.
A European bioengineer has pushed the boundaries of cell manipulation by pioneering a new, droplet-based method of study. His innovation, allowing for the highly detailed observation of cells, has resulted in the launch of a spin-off company as well as further research into cell cultures. Fuelled by a European Research Council (ERC) grant, the technology promises to open doors to new applications in pharmaceuticals, diagnostics and medical research.
Stressed plants typically stop growing. With her ERC grant, Prof. Ana Caño-Delgado has developed and is applying an innovative approach to generate drought-resistant plants that continue growing. This could play an important role in ensuring food security when water is scarce.
Maternal microbiota is crucial for the future health of a child. The transmission of microbes to offspring is a process that begins in the uterus and is influenced by the delivery method, breastfeeding and the mother’s diet. However, the mechanisms behind the protective role of maternal microbes on the baby’s health are not yet fully understood.
Multifunctional nanoparticles being developed by EU-funded researchers are set to revolutionise treatments for complex bone diseases, enabling novel therapies for hundreds of millions of people worldwide suffering from bone cancer, bacterial bone infections and osteoporosis.
CRISPR is a widely used molecular biology tool exploiting an immune process discovered in bacteria. Dr David Bikard studies CRISPR in bacterial cells, in conjunction with different DNA repair systems, to create even newer tools. He hopes to gain insight into bacterial genetics, and develop increasingly effective medical treatments.
Epithelial tissues cover all body surfaces and line most of our organs, internal cavities and passageways, including the digestive tract. Prof. Elena Martínez is engineering intestinal epithelial tissues that mimic the physiological characteristics of human intestinal tissue with the aim of advancing the in vitro modelling of diseases, the preclinical screening for drug efficacy and toxicity, and the understanding of organ development.
Emulsions play a key role both in natural and industrial processes, as they allow the combination of two liquids that do not normally mix and make the blend stable. Yet, when materials solidify or freeze, the complex interactions that take place and affect the final microstructure of the solidified components, are still poorly understood. ERC grantee Sylvain Deville and his team at CNRS have showed that it is possible to use an optical imaging technique to study the freezing of emulsions while the process takes place, a novel method presented in the prestigious journal Science.
Headscarves, mosques and halal shops — many EU citizens are Muslims, but visible signs of their faith are often viewed with distrust. What some Europeans see as a right to express their identity, others regard as a threat to societal core values. Insights from ERC-funded research into emblematic controversies may help to find a way forward.
The use and misuse of antibiotics has accelerated the emergence of drug-resistant bacterial strains, threatening our ability to treat common diseases. EU-funded research has shed new light on the mechanisms behind these microbial mutations, with implications for our understanding of diseases and resistance to treatment.