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Until recently, lungs were believed to be sterile, but today we know that they are inhabited by microbes migrating from the mouth. Dr Randi Bertelsen has been awarded an ERC grant to investigate the role played by the oral microbiome in lung disease.
The abundant presence of a certain bacteria in our intestine, Akkermansia muciniphila, to give it its full name, is an excellent sign according to metabolism and nutrition specialist prof. Patrice Cani. With his team, they discovered the role of these bacteria in reducing cardiometabolic risk factors - like insulin resistance or hypertension – that are leading causes in the development of cardiovascular diseases and type-2 diabetes.
ELECTION SERIES #1
There is now more information circulating than at any other time in history. Every day mind-boggling amounts of data are produced, reaching over 2.5 quintillion bytes. With the European elections just around the corner, we take a look at an ERC funded project on how politicians stay knowledgeable amidst this information overload. The research by grantee Prof. Stefaan Walgrave from the University of Antwerp compares how different politicians process information and then act on it in three western, post-industrialist parliamentary democracies - Israel, Belgium and Canada. An original study, which unveils some optimistic findings just as voters prepare to head to the polls.
More than 100 million people worldwide suffer from valvular heart disease, affecting one or more of the heart’s four valves and causing breathlessness, chest pain, dizziness and fainting. If severe valvular heart disease is not properly treated, chances of surviving decrease, especially in the elderly. The only effective therapy is heart valve replacement, which may entail some risks and lead to revision surgeries. What can be done to improve safety and durability of artificial heart valves?
The human brain is a remarkable organ, but how did it evolve to give us such unprecedented cognitive abilities? ERC grantee Pierre Vanderhaeghen and his team from ULB, VIB-KU Leuven turned to the genome for answers: a specific set of genes, found only in humans, could play a determinant role on the size of our brain. Published today in Cell, Vanderhaeghen's EU-funded research helps to unlock the secrets of human evolution.
'Silent killers'. This is how liver diseases are often described. But, are they really that silent? ERC grantee Mathieu Vinken, a pharmacist by training and worldwide expert in toxicology based at Vrije Universiteit Brussel (VUB), has just proven the contrary.
The use and misuse of antibiotics has accelerated the emergence of drug-resistant bacterial strains, threatening our ability to treat common diseases. EU-funded research has shed new light on the mechanisms behind these microbial mutations, with implications for our understanding of diseases and resistance to treatment.
Regulating migration has become a key priority for European countries and, according to Prof. Katja Franko, crime control practices and penal cultures have evolved across the continent as a consequence. With ERC support, she has studied these new hybrid and intertwined forms of migration and crime control policies, a phenomenon she calls ‘Crimmigration control’.
Some school systems in Europe are highly segregated, the Belgian one especially. Poorer standards of education are seen in schools where pupils are predominantly of immigrant background. Researchers are compiling new datasets and information about school composition and teaching cohesion to ensure segregation does not have to mean a difference in education standards.
Maria Brandão de Vasconcelos, together with her colleague Filipa Matos Baptista, Henrique Veiga-Fernandes (ERC grantee), Diogo Fonseca Pereira and Sílvia Arroz Madeira, founded StemCell2MAX in 2015. The company is a biotechnology start-up, specialised in cell based therapies, including novel solutions to multiply the scarcely available blood stem cells, addressing an enormous demand for research and cancer treatment. StemCell2MAX technology is based on Prof. Veiga-Fernandes's ground-breaking discoveries in hematopoietic stem cell biology.
Originally published in March 2017 as part of the multimedia campaign "ERC - 10 years – 10 portraits."