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24-06-2019 | © istockphotos.com 2 mins read

Healthy lungs start from your toothbrush

Until recently, lungs were believed to be sterile, but today we know that they are inhabited by microbes migrating from the mouth. Dr Randi Bertelsen has been awarded an ERC grant to investigate the role played by the oral microbiome in lung disease.

22-05-2018 | © picture 6 mins read

Sailing the mysteries of old maps

Dr Joaquim Alves Gaspar is a man of the sea. After many years in the Portuguese Navy, he gave up plans to become an admiral in favour of pursuing a PhD in the History of Cartography. This second career led him to receive an ERC Starting Grant, the first awarded in this budding discipline. With his highly multidisciplinary team (he likes to say that, to work with him, one must be a mathematician fluent in Latin), and the experience obtained as a navigator and navigational instructor, Dr Gaspar hopes to understand how and when the first nautical charts were created. The MEDEA-CHART team is the best place in Portugal, and probably in the world, to study the history of nautical cartography, hoping that this work will provide the domain with its rightful recognition within world history.

11-05-2017 | Portrait and illustration: Photo Evolutionary Biology group (Isabel Gordo) | llustration: Macrophages with Escherichia coli 3 mins read

New knowledge to fight back against antibiotic resistance

The use and misuse of antibiotics has accelerated the emergence of drug-resistant bacterial strains, threatening our ability to treat common diseases. EU-funded research has shed new light on the mechanisms behind these microbial mutations, with implications for our understanding of diseases and resistance to treatment.

01-04-2017 | © picture 2 mins read

Frontier science and business that makes a difference

Maria Brandão de Vasconcelos, together with her colleague Filipa Matos Baptista, Henrique Veiga-Fernandes (ERC grantee), Diogo Fonseca Pereira and Sílvia Arroz Madeira, founded StemCell2MAX in 2015. The company is a biotechnology start-up, specialised in cell based therapies, including novel solutions to multiply the scarcely available blood stem cells, addressing an enormous demand for research and cancer treatment. StemCell2MAX technology is based on Prof. Veiga-Fernandes's ground-breaking discoveries in hematopoietic stem cell biology.

Originally published in March 2017 as part of the multimedia campaign "ERC - 10 years – 10 portraits."

29-06-2016 | © picture 2 mins read

Stem cells: from frontier research project to promising spin-off company

Haematopoietic Stem Cells (HSCs) are blood cells located in the bone marrow. These cells are extensively used in research to develop treatments for many severe diseases, including HIV and multiple sclerosis, and their transplant is a key therapy for certain types of cancer like leukemia and multiple myeloma. However, the use of HSCs is seriously constrained by their limited availability since growing them in the lab does not produce very large quantities. There is therefore an urgent need for methods allowing scientists to multiply HSCs, without losing any of their properties.

30-10-2015 | image © Istockphoto 2 mins read

Animals "peer-pressured" into reacting to danger

ERC grantee Marta Moita and her team use cutting-edge experimental procedures to investigate how rats and flies learn to appropriately respond to danger from other individuals. The results of her study may teach us a lot about our own brains, and shed light on diseases that impair social behaviour.

26-07-2012 | © F. d’Errico and L. Backwell, Production of ostrich egg shell beads by a San craftsman 2 mins read

Modern human culture could have emerged 44,000 years ago

In cooperation with the CNRS and University of Bergen When did human behaviour as we know it begin? Work conducted by an international team of researchers suggests that modern culture emerged 44,000 years ago. Their analysis of archaeological material discovered at Border Cave in South Africa has demonstrated that much of the material culture that characterized the lifestyle of San hunter-gatherers in southern Africa was part of the culture and technology of the inhabitants of Border Cave 44,000 years ago. This research, funded by an ERC Advanced Grant, is published in the online edition of the Proceedings of the National Academy of Sciences.