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Sponges seem an unlikely source for innovation, yet they may hold the key to new nanotechnologies, innovative optical devices and new ways of regrowing human bone and preventing bone disease. Difficult to believe? Not for Werner E.G. Müller. In the BIOSILICA project, he and his team are developing ways to adapt the complex processes that natural glassy sponges use to build their wondrous biosilica structures for use in biodegradable implants that would facilitate bone healing after surgery or fractures.
The ability to fine-tune the functioning of blood vessels and the circulatory system is essential for combating the remodelling of the arteries that leads to heart attacks and strokes. It is also needed for the controlled repair of blood vessels after injury – which may otherwise result in a number of serious conditions. ERC grantee Professor Stefanie Dimmeler and her team at Frankfurt University are studying the role ribonucleic acid (RNA) plays in fine-tuning vascular functions – with the aim of developing new therapies for cardiovascular diseases, which are the most prevalent in Europe, due to growing obesity and longer lifespans.