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Most of our actions can have an impact on the environment, be it minor, long-lasting or simply irreversible. But how can this effect be measured, avoided, predicted? What are the specificities of long-term risks and how can collective decisions be taken effectively to tackle those threats?
For the first time ever, two ERC grantees, Prof. Luca G. Guidotti and Dr Matteo Iannacone, have observed in vivo how specific white blood cells, so-called cytotoxic T lymphocytes, identify, target and attack liver cells that are infected with the hepatitis B virus. To witness these immune cells in action in real time, the two scientists developed advanced, dynamic imaging techniques. An estimated 240 million people are chronically infected with hepatitis B worldwide. This discovery, published today in the scientific journal Cell, opens new horizons for the development of novel therapies.