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A European biologist has pioneered a new way of looking at biodiversity change, with the help of the European Research Council (ERC). A key result of this work has been the launch of an open-access biodiversity database, which will help researchers and conservation managers find sustainable solutions to protect wildlife.
Bacteria fight big. When they meet competitors, they are as aggressive and bloodthirsty as they come. ERC grantee Kevin Foster studies how bacteria wage war against each other. His aim is to understand what led to the evolution of such extreme competitive behaviours, and how to exploit them for our own health.
Our soils are inhabited by millions of microorganisms; however, the majority of them lay dormant. In her ERC project, Prof. Dagmar Woebken explores the mechanisms that allow soil microorganisms to go into dormancy and thus survive unfavorable conditions. It is further the goal to reveal the environmental signals that lead to their resuscitation to perform important ecosystems functions.
The deep seafloor covers around 70% of our planet’s surface and is home to a diverse community of microorganisms, mostly bacteria. These single-cell life forms inhabit some of the most extreme places in the world, with freezing waters, permanent darkness, high pressure and little food. ERC grantee Antje Boetius studies these microbes in the abyss and their important role for the Earth’s nutrient cycles.
Honey bees are an important species for ecology and economy, but their population has shrank worryingly. Prof. Philipp Engel focuses on gut microbiota, a critical factor for bee health, to understand how it evolved and diversified over time. His study addresses timely questions about evolution, ecology, microbiology and could eventually contribute to new strategies for managing bee colonies’ health.
Until recently, lungs were believed to be sterile, but today we know that they are inhabited by microbes migrating from the mouth. Dr Randi Bertelsen has been awarded an ERC grant to investigate the role played by the oral microbiome in lung disease.
Tamoxifen, a drug used in breast cancer treatment, may be repositioned to treat pancreatic cancer
Pancreatic cancer is the 4th leading cause of death by cancer in Europe. It has a very low survival rate with less than 1 per cent of sufferers surviving for 10 or more years. Over the last 40 years the survival rate has not significantly changed and finding an effective therapy has become a pressing challenge in cancer research. A team based at Imperial College London led by Armando Del Río Hernández, has now demonstrated that a well-known drug could be effective to fight this deadly and other forms of cancer, such as liver cancer.
Based on University of Turku's press release
For more than 3000 years, men have captured wild Asian elephants to use them for work or entertainment. In a new study published today in Nature Communications, ERC grantee Virpi Lummaa shows the harmful effects of these ongoing practices on wild-caught animals. The findings are based on detailed records from the past 100 years over a population of 5000 timber elephants from Myanmar.
CRISPR is a widely used molecular biology tool exploiting an immune process discovered in bacteria. Dr David Bikard studies CRISPR in bacterial cells, in conjunction with different DNA repair systems, to create even newer tools. He hopes to gain insight into bacterial genetics, and develop increasingly effective medical treatments.
The use and misuse of antibiotics has accelerated the emergence of drug-resistant bacterial strains, threatening our ability to treat common diseases. EU-funded research has shed new light on the mechanisms behind these microbial mutations, with implications for our understanding of diseases and resistance to treatment.