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Historically, due to a difference in lifestyles, men were at a higher risk of suffering from a heart attack or stroke than women. While this is no longer the case, obsolete stereotypes and misconceptions mean these conditions in women are often misdiagnosed. ERC grantee Nabila Bouatia-Naji aims to decipher the genetic and molecular causes of two devastating cardiovascular diseases which commonly affect women under 60. Her work could lead to a better understanding of these diseases and to improvements in treatment.
A targeted and personalised method for triggering the body’s immune response could transform how we treat cancer. Thanks to a grant from the European Research Council (ERC), an inspired idea has been developed in the lab and turned into a ground-breaking commercial opportunity.
About the size of a big cherry, the first-of-its-kind 3D printed heart has cells, blood vessels, ventricles and chambers. This feat is the work of Prof. Tal Dvir and his team at Tel Aviv University. They managed to engineer such miniature organs using cells and biological materials that are originated from human patients. Besides the remarkable technical achievement, this breakthrough could potentially be the answer to the shortage of organ donors in the future.
Stressed plants typically stop growing. With her ERC grant, Prof. Ana Caño-Delgado has developed and is applying an innovative approach to generate drought-resistant plants that continue growing. This could play an important role in ensuring food security when water is scarce.
New families of proteins and enzymes will enable the development of novel plant-based biomaterials, potentially providing viable sustainable and renewable alternatives to plastics and other fossil-fuel-derived materials and chemicals.
Maternal microbiota is crucial for the future health of a child. The transmission of microbes to offspring is a process that begins in the uterus and is influenced by the delivery method, breastfeeding and the mother’s diet. However, the mechanisms behind the protective role of maternal microbes on the baby’s health are not yet fully understood.
Effective treatment for obesity remains a challenge and the only intervention proven to maintain weight loss is bariatric surgery. Intrigued by the beneficial effect that this procedure has on the composition of gut microbiota, Dr Fredrik Bäckhed explores the possibility of mimicking these changes to develop a treatment for obesity that won’t require going under the knife.
EU-funded researchers planted, harvested, processed and analysed the life cycle of woody crops to establish how efficient and environmentally friendly they are as a source of fuel for electricity and heat.
Diseases affecting the retina cause one quarter of worldwide blindness. To date, there are no treatments to restore lost retinal cells and visual function, making it urgent to find new therapeutic approaches. Can stem cells be the solution? Prof. Majlinda Lako aims at growing artificial replicas of the human retina using stem cells.
The abundant presence of a certain bacteria in our intestine, Akkermansia muciniphila, to give it its full name, is an excellent sign according to metabolism and nutrition specialist prof. Patrice Cani. With his team, they discovered the role of these bacteria in reducing cardiometabolic risk factors - like insulin resistance or hypertension – that are leading causes in the development of cardiovascular diseases and type-2 diabetes.