The tails of our DNA – telomeres – are the focus of many aging studies, as their length affects our health and longevity. A new study by ERC grantee Sonja Entringer shows that supporting the psychological wellbeing of mothers during pregnancy could have a positive effect on our telomeres at birth, boosting our long-term health. We spoke with her on the occasion of the publication of a paper in the American Journal of Psychiatry based on a collaboration between her team at the Charité Universitätsmedizin Berlin, and partners in Finland and the USA.
About the size of a big cherry, the first-of-its-kind 3D printed heart has cells, blood vessels, ventricles and chambers. This feat is the work of Prof. Tal Dvir and his team at Tel Aviv University. They managed to engineer such miniature organs using cells and biological materials that are originated from human patients. Besides the remarkable technical achievement, this breakthrough could potentially be the answer to the shortage of organ donors in the future.
Diseases affecting the retina cause one quarter of worldwide blindness. To date, there are no treatments to restore lost retinal cells and visual function, making it urgent to find new therapeutic approaches. Can stem cells be the solution? Prof. Majlinda Lako aims at growing artificial replicas of the human retina using stem cells.
Key nutrients can improve vision both in ageing and in healthy eyes, according to EU-funded research. Doctors are now prescribing supplements of these nutrients, while the researchers are investigating other possible health benefits.
An EU-funded project is exploring what keeps people committed to a task even when they get bored, distracted or are tempted to stop. The findings could foster productivity-boosting strategies, improve robot-human interactions and even help treat borderline personality disorder.
At the forefront of medicine, gene therapy is based on the insertion of genes into an individual's cells and tissues to treat a disease. Scientists are currently testing several approaches to this experimental technique. One of them, Prof. Seppo Ylä-Herttuala, intends to develop a novel method to treat myocardial ischemia by activating endogenous genes to propel angiogenesis. If successful, he will open a new era in gene therapy.
More than 100 million people worldwide suffer from valvular heart disease, affecting one or more of the heart’s four valves and causing breathlessness, chest pain, dizziness and fainting. If severe valvular heart disease is not properly treated, chances of surviving decrease, especially in the elderly. The only effective therapy is heart valve replacement, which may entail some risks and lead to revision surgeries. What can be done to improve safety and durability of artificial heart valves?
Cell transplantation is a promising new approach for organ regeneration in disease or after injury. To support the differentiation of hepatocytes from stem cells, European researchers developed ex vivo organoids which precisely mimic liver architecture.
'Silent killers'. This is how liver diseases are often described. But, are they really that silent? ERC grantee Mathieu Vinken, a pharmacist by training and worldwide expert in toxicology based at Vrije Universiteit Brussel (VUB), has just proven the contrary.
For the first time ever, a team of scientists and clinicians led by the EU-funded researcher Mickael Tanter has managed to record the brain activity of a premature new-born baby during resting and during an epileptic seizure. Using a non-invasive ultrasound technology, this world premiere is a real game changer for researchers and the medical profession, offering a massive range of applications in neuroimaging and beyond. It is published today in Science Translational Medicine.
