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At the forefront of medicine, gene therapy is based on the insertion of genes into an individual's cells and tissues to treat a disease. Scientists are currently testing several approaches to this experimental technique. One of them, Prof. Seppo Ylä-Herttuala, intends to develop a novel method to treat myocardial ischemia by activating endogenous genes to propel angiogenesis. If successful, he will open a new era in gene therapy.
More than 100 million people worldwide suffer from valvular heart disease, affecting one or more of the heart’s four valves and causing breathlessness, chest pain, dizziness and fainting. If severe valvular heart disease is not properly treated, chances of surviving decrease, especially in the elderly. The only effective therapy is heart valve replacement, which may entail some risks and lead to revision surgeries. What can be done to improve safety and durability of artificial heart valves?
Water is a peculiar liquid. In fact, it's thanks to some of its peculiarities that our "blue" planet looks the way it does, and that life has evolved most of the characteristics we recognise today. ERC grantee Prof. Anders Nilsson has made his career out of studying water, in particular trying to understand the secret double life water leads at extremely cold temperatures.
Based on University of Turku's press release
For more than 3000 years, men have captured wild Asian elephants to use them for work or entertainment. In a new study published today in Nature Communications, ERC grantee Virpi Lummaa shows the harmful effects of these ongoing practices on wild-caught animals. The findings are based on detailed records from the past 100 years over a population of 5000 timber elephants from Myanmar.
Group theory, functional analysis and ergodic theory – three distinct areas of mathematics that meet within the theory of von Neumann algebras. The RIGIDITY project, funded by the ERC, aims to classify families of von Neumann algebras.
Understanding complex structures means separating irrelevant information to get to something simpler and easier to understand. When you look at something from a distance – although you don’t see all the details, you can still describe what you see. ERC grantee Balázs Szegedy has developed several mathematical tools for providing a compressed yet useful view of complex structures.
How does one infer the dynamics of a DNA minicircle in solution? How does one align the neuronal firing patterns of several neurons across individuals? These questions are intrinsically statistical, but nevertheless escape the traditional tools of statistics. The ComplexData project investigated such questions from a mathematical and an applied context.
Once limited to modelling physical problems in engineering, today Partial Differential Equations (PDEs) are used by a diverse array of fields, from natural resources to meteorology, aeronautics, oil and gas and biomedicine – to name only a few. But key mathematical issues remain unsolved, particularly when addressing their control, a must in technological transfer. The ERC-funded DYCON project aims to find answers.
Funded by the ERC, Prof. Anna Wienhard studies several new geometric forms that have been discovered over the past 20 years. These structures are closely related to the generalisation of Teichmüller space, which describes how the surface of a pretzel can be endowed with the geometry of an Escher painting.
How do you study arithmetic objects like integer points using the theory of dynamical systems? The answer is homogenous dynamics, and this connection goes both ways. The GMODGAMMADYNAMICS project, funded by an ERC grant, took a broad approach towards studying this rich interplay.