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Toxicology and pharmacology assays are currently carried out in cell lines or experimental animals. Scientists of the TOXANOID project developed mini organs in a dish, which outperform existing in vitro systems.
Colorectal cancer (CRC) is the second most common cause of cancer-related deaths. European researchers developed novel ex vivo three-dimensional organoid cultures that replicate genetic events in CRC, as tools to test novel therapeutics.
Cell transplantation is a promising new approach for organ regeneration in disease or after injury. To support the differentiation of hepatocytes from stem cells, European researchers developed ex vivo organoids which precisely mimic liver architecture.
Neglect, pollution, natural hazards and climate change are all playing their part in the damage to cultural heritage. This non-renewable resource, in all its diverse physical forms, needs safeguarding for future generations. EU-funded research projects have been carefully investigating the preservation and the sustainable management of these valuable assets to increase their overall resilience. Innovative solutions and techniques, assessment systems, mitigation strategies, risk management models, disaster prevention, quick damage assessment, ICT tools and guidelines have been some of the major results successfully delivered by both FP7 and H2020 projects in the field of cultural heritage.
Vernachlässigung, Umweltbelastung, Naturgefahren und der Klimawandel tragen alle zur Schädigung des kulturellen Erbes bei. Diese nicht erneuerbare Ressource muss in all ihren verschiedenen physischen Formen für zukünftige Generationen bewahrt werden. EU-finanzierte Forschungsvorhaben, einschließlich der Vorhaben, die in diesem neuen CORDIS Results Pack vorgestellt wurden, haben die Erhaltung und nachhaltige Bewirtschaftung dieser wertvollen Kulturgüter sorgfältig untersucht, um ihre allgemeine Widerstandsfähigkeit zu erhöhen. Innovative Lösungen und Techniken, Bewertungssysteme, Minderungsstrategien, Risikomanagementmodelle, Katastrophenvorbeugung, eine schnelle Schadensbewertung sowie IKT-Tools und -Leitlinien gehörten zu den wichtigsten Ergebnissen, die sowohl im Rahmen der RP7- als auch der H2020-Projekte im Bereich des kulturellen Erbes erfolgreich erzielt wurden.
Incuria, inquinamento, calamità naturali e cambiamenti climatici stanno tutti facendo la loro parte nel danneggiamento del patrimonio culturale. Questa risorsa non rinnovabile, in tutte le sue varie forme fisiche, ha bisogno di essere salvaguardata per le generazioni future. Progetti di ricerca finanziati dall’UE, inclusi quelli presentati in questo nuovo CORDIS Results Pack, hanno studiato con attenzione la conservazione e la gestione sostenibile di questi preziosi beni al fine di aumentare la loro resilienza complessiva. Soluzioni e tecniche innovative, sistemi di valutazione, strategie di mitigazione, modelli di gestione dei rischi, prevenzione delle catastrofi, valutazione rapida dei danni, strumenti TIC e linee guida sono stati alcuni dei principali risultati ottenuti sia da progetti del 7° PQ sia di Orizzonte 2020 nel campo del patrimonio culturale.
ERC grantee Alvaro Mata, from Queen Mary’s School of Engineering and Materials Science, has developed a new way to grow mineralised materials which could regenerate hard tissues such as dental enamel and bone. The findings are reported today in Nature Communications.
The human brain is a remarkable organ, but how did it evolve to give us such unprecedented cognitive abilities? ERC grantee Pierre Vanderhaeghen and his team from ULB, VIB-KU Leuven turned to the genome for answers: a specific set of genes, found only in humans, could play a determinant role on the size of our brain. Published today in Cell, Vanderhaeghen's EU-funded research helps to unlock the secrets of human evolution.
'Silent killers'. This is how liver diseases are often described. But, are they really that silent? ERC grantee Mathieu Vinken, a pharmacist by training and worldwide expert in toxicology based at Vrije Universiteit Brussel (VUB), has just proven the contrary.
Prof. Giulio Superti-Furga and his team work on understanding the movement of molecules across human cells. In a paper recently published on Cell Host & Microbe, they outline the significance of a single protein, SLC4A7, in phagocytosis, the body's first line of defence against infection. These results, however, go beyond the context of infectious diseases, with repercussions on our knowledge of processes like inflammation and cancer.